Publications
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23 peer reviewed publications from 2023
Schmitt, P. and Borkner, L. and Jazayeri, S.D. and McCarthy, K.N. and Mills, K.H., Nasal vaccines for pertussis, Current Opinion in Immunology, 84, (102355), 2023
Diallo, B.K. and Chasaide, C.N. and Wong, T.Y. and Schmitt, P. and Lee, K.S. and Weaver, K. and Miller, O. and Cooper, M. and Jazayeri, S.D. and Damron, F.H. and Mills, K.H.G., Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection, npj Vaccines, 8, (1), 2023
Ryan, T.A.J. and Hooftman, A. and Rehill, A.M. and Johansen, M.D. and Brien, E.C.O. and Toller-Kawahisa, J.E. and Wilk, M.M. and Day, E.A. and Weiss, H.J. and Sarvari, P. and Vozza, E.G. and Schramm, F. and Peace, C.G. and Zotta, A. and Miemczyk, S. and Nalkurthi, C. and Hansbro, N.G. and McManus, G. and Oâ Doherty, L. and Gargan, S. and Long, A. and Dunne, J. and Cheallaigh, C.N. and Conlon, N. and Carty, M. and Fallon, P.G. and Mills, K.H.G. and Creagh, E.M. and Donnell, J.S.O. and Hertzog, P.J. and Hansbro, P.M. and McLoughlin, R.M. and Wygrecka, M. and Preston, R.J.S. and ZasÅ'ona, Z. and Neill, L.A.J.O., Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon, Nature Communications, 14, (1), 2023
Ryan, T.A.J. and Hooftman, A. and Rehill, A.M. and Johansen, M.D. and Oâ Brien, E.C. and Toller-Kawahisa, J.E. and Wilk, M.M. and Day, E.A. and Weiss, H.J. and Sarvari, P. and Vozza, E.G. and Schramm, F. and Peace, C.G. and Zotta, A. and Miemczyk, S. and Nalkurthi, C. and Hansbro, N.G. and McManus, G. and Oâ Doherty, L. and Gargan, S. and Long, A. and Dunne, J. and Cheallaigh, C.N. and Conlon, N. and Carty, M. and Fallon, P.G. and Mills, K.H.G. and Creagh, E.M. and Oâ Donnell, J.S. and Hertzog, P.J. and Hansbro, P.M. and McLoughlin, R.M. and Wygrecka, M. and Preston, R.J.S. and ZasÅ'ona, Z. and Oâ Neill, L.A.J., Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon (Nature Communications, (2023), 14, 1, (3513), 10.1038/s41467-023-39174-1), Nature Communications, 14, (1), 2023
Wang S., Malebari A.M., Greene T.F., Kandwal S., Fayne D., Nathwani S.M., Zisterer D.M., Twamley B., O'Boyle N.M., Meegan M.J., Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells, Pharmaceuticals, 16, (7), 2023, p1000-
Haley R. Dolton, Andrew L. Jackson, Robert Deaville, Jackie Hall , Graham Hall , Gavin McManus , Matthew W. Perkins , Rebecca A. Rolfe , Edward P. Snelling , Jonathan D. R. Houghton , David W. Sims Nicholas L. Payne, Regionally endothermic traits in planktivorous basking sharks Cetorhinus maximus, ENDANGERED SPECIES RESEARCH, 51, 2023, p227 - 232
Kate Keogh, Clare McKenna, Sinead M. Waters, Richard K. Porter, Claire Fitzsimons, Mark McGee & David A. Kenny, Effect of breed and diet on the M. longissimus thoracis et lumborum transcriptome of steers divergent for residual feed intake, Scientific Reports , 13(9034), 2023
Baran, M. and Feriotti, C. and McGinley, A. and Carlile, S.R. and Jiang, Z. and Calderon-Gonzalez, R. and Dumigan, A. and Sá-Pessoa, J. and Sutton, C.E. and Kearney, J. and McLoughlin, R.M. and Mills, K.H.G. and Fitzgerald, K.A. and Bengeochea, J.A. and Bowie, A.G., PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection, Cell Reports, 42, (4), 2023
Cunningham KT, Mills KHG., Modulation of haematopoiesis by protozoal and helminth parasites., Parasite immunology, 2023, pe12975
Hambly R, Gatault S, Smith CM, Iglesias-Martinez LF, Kearns S, Rea H, Marasigan V, Lynam-Loane K, Kirthi S, Hughes R, Fletcher JM, Kolch W, Kirby B., B-cell and complement signature in severe hidradenitis suppurativa that does not respond to adalimumab., The British journal of dermatology, 188, (1), 2023, p52-63
Smith CM, Hambly R, Gatault S, Iglesias-Martinez LF, Kearns S, Rea H, Marasigan V, Lynam-Loane K, Kirthi S, Hughes R, Fletcher JM, Kolch W, Kirby B., B-cell-derived transforming growth factor-ß may drive the activation of inflammatory macrophages and contribute to scarring in hidradenitis suppurativa., The British journal of dermatology, 188, (2), 2023, p290-310
Huete-Carrasco J, Lavelle EC., Immunostimulatory nanoparticles go viral., Nature materials, 22, (3), 2023, p273-275
Barker BE, Hanlon MM, Marzaioli V, Smith CM, Cunningham CC, Fletcher JM, Veale DJ, Fearon U, Canavan M., The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis., Frontiers in medicine, 10, 2023, p1029021
Petrasca A, Hambly R, Molloy O, Kearns S, Moran B, Smith CM, Hughes R, O'Donnell M, Zaborowski A, Winter D, Fletcher JM, Kirby B, Malara A., Innate lymphoid cell (ILC) subsets are enriched in the skin of patients with hidradenitis suppurativa., PloS one, 18, (2), 2023, pe0281688
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ., Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. , Nature, 2023, p32
McGettrick AF, O'Neill LA., Two for the price of one: itaconate and its derivatives as an anti-infective and anti-inflammatory immunometabolite., Current opinion in immunology, 80, 2023, p102268
Zhang, Jilei, Zhang, Yongguo, McGrenaghan, Callum J., Kelly, Vincent P., Xia, Yinglin, Sun, Jun, Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel Disease, Cellular and Molecular Gastroenterology and Hepatology, 2023
Hung SH, Elliott GI, Ramkumar TR, Burtnyak L, McGrenaghan CJ, Alkuzweny S, Quaiyum S, Iwata-Reuyl D, Pan X, Green BD, Kelly VP, de Crécy-Lagard V, Swairjo MA., Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate., Nucleic acids research, 51, (2), 2023, p935-951
Sake JA, Selo MA, Burtnyak L, Dähnhardt HE, Helbet C, Mairinger S, Langer O, Kelly VP, Ehrhardt C., Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 181, 2023, p106364
Muñoz-Wolf, N. and Ward, R.W. and Hearnden, C.H. and Sharp, F.A. and Geoghegan, J. and O'Grady, K. and McEntee, C.P. and Shanahan, K.A. and Guy, C. and Bowie, A.G. and Campbell, M. and Roces, C.B. and Anderluzzi, G. and Webb, C. and Perrie, Y. and Creagh, E. and Lavelle, E.C., Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles, Cell Reports Medicine, 4, (1), 2023
Curham, L.M. and Mannion, J.M. and Daly, C.M. and Wilk, M.M. and Borkner, L. and Lalor, S.J. and McLoughlin, R.M. and Mills, K.H.G., Bystander activation of Bordetella pertussis-induced nasal tissue-resident memory CD4 T cells confers heterologous immunity to Klebsiella pneumoniae, European Journal of Immunology, 2023
O'Connor, C., Jordan, K., Vagg, T., Murphy, C.E., Barry, D.B., Toulouse, A., Flecther, J., Downer, E.J. , Animated teaching improves student learning of human gastrulation and neurulation., Annals of Anatomy, in press, 2023
Mills, K.H.G., IL-17 and IL-17-producing cells in protection versus pathology, Nature Reviews Immunology, 2023, p38-54