Publications
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115 peer reviewed publications from 2009
Pettersson-Kastberg, J., Mossberg, A.-K., Trulsson, M., Yong, Y.J., Min, S., Lim, Y., O'Brien, J.E., Svanborg, C., Mok, K.H., "-Lactalbumin, Engineered to be Nonnative and Inactive, Kills Tumor Cells when in Complex with Oleic Acid: A New Biological Function Resulting from Partial Unfolding, Journal of Molecular Biology, 394, (5), 2009, p994-1010
Murphy, J.E.J. and Porter, R.K., The control of oxidative phosphorylation in the adrenal gland (Y1) cell line, Advances in Experimental Medicine and Biology, 645, 2009, p35-41
Ryan, T.J. and Grant, S.G.N., Erratum: The origin and evolution of synapses (Nature Reviews Neuroscience (2009) 10 (701-712)), Nature Reviews Neuroscience, 10, (11), 2009, p829
Richard K. Porter, "Mitochondrial Uncoupling Protein 1 and Immune Function" , COST meeting , Balearic Islands University, Palma, Mallorca, Spain., March, 2009, COST Mitofood
Richard K. Porter, "Efficiency of Energy Transduction in Mammals" , Invitation to Nencki Institute Warsaw, Poland., Nencki Institute Warsaw, Poland., July, 2009, Adam Szewczyk
Ryan, T.J., Grant, S.G.N., The origin and evolution of synapses, 10, (10), 2009, p701-712
Daniela Zisterer, Mary Meegan, Niamh O'Boyle, Miriam Carr, Lisa Greene and Thomas Greene, 'Combretastatin Derivatives and Uses Therefor', European Patent Office, EP2338877 A1, 2009
Lee, JH ; Budanov, AV ; Bier, E ; Karin, M, Sestrin, a novel regulator of TOR-dependent cell growth and metabolism, DEVELOPMENTAL BIOLOGY, 68th Annual Meeting of the Society-for-Developmental-Biology, San Francisco, CA, JUL 23-27, 331, (2), ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2009, pp481 - 481
Onnis, V., Kinsella, G.K., Carta, G., Fayne, D., Lloyd, D.G., Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-", Future Medicinal Chemistry, 1, (3), 2009, p483-499
Stevenson, N.J., Addley, M.R., Ryan, E.J., Boyd, C.R., Carroll, H.P., Paunovic, V., Bursill, C.A., Miller, H.C., Channon, K.M., McClurg, A.E., Armstrong, M.A., Coulter, W.A., Greaves, D.R., Johnston, J.A., CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression, Journal of Leukocyte Biology, 85, (2), 2009, p289-297
Meade, K.G., Narciandi, F., Cahalane, S., Reiman, C., Allan, B., O'Farrelly, C., Comparative in vivo infection models yield insights on early host immune response to Campylobacter in chickens, Immunogenetics, 61, (2), 2009, p101-110
Lynch, L.A., O'Connell, J.M., Kwasnik, A.K., Cawood, T.J., O'Farrelly, C., O'Shea, D.B., Are natural killer cells protecting the metabolically healthy obese patient?, Obesity, 17, (3), 2009, p601-605
Mcgrath, E., Ryan, E.J., Lynch, L., Golden-Mason, L., Mooney, E., Eogan, M., O'herlihy, C., O'Farrelly, C., Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility, American Journal of Reproductive Immunology, 61, (4), 2009, p265-276
Chapwanya, A., Meade, K.G., Doherty, M.L., Callanan, John.J., Mee, J.F., O'Farrelly, C, Histopathological and molecular evaluation of Holstein-Friesian cows postpartum: Toward an improved understanding of uterine innate immunity, Theriogenology, 71, (9), 2009, p1396-1407
Nanda, K.S., Ryan, E.J., Murray, B.F., Brady, J.J., McKenna, M.J., Nolan, N., O'Farrelly, C., Hegarty, J.E., Effect of Chronic Hepatitis C Virus Infection on Bone Disease in Postmenopausal Women, Clinical Gastroenterology and Hepatology, 7, (8), 2009, p894-899
MacHugh, D.E., Gormley, E., Park, S.D.E., Browne, J.A., Taraktsoglou, M., O'Farrelly, C., Meade, K.G., Gene expression profiling of the host response to mycobacterium bovis infection in cattle, Transboundary and Emerging Diseases , 56, (6-7), 2009, p204-214
Nemeth, E., Baird, A.W., O'Farrelly, C., Microanatomy of the liver immune system, Seminars in Immunopathology, 31, (3), 2009, p333-343
O'Neill, L.A.J., O'Farrelly, C., The immune system as an invisible, silent Grand Fugue, Nature Immunology, 10, (10), 2009, p1043-1045
Meade, K.G., O'Gorman, G.M., Hill, E.W., Narciandi, F., Agaba, M., Kemp, S.J., O'Farrelly, C., MacHugh, D.E., Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle, Molecular Immunology, 47, (2-3), 2009, p196-204
Fernandes, H., Franklin, E., Recacha, R., Houdusse, A., Goud, B., Khan, A.R., Structural aspects of Rab6-effector complexes, Biochemical Society Transactions, 37, (5), 2009, p1037-1041
Crowley, P.B., Matias, P.M., Khan, A.R., Roessle, M., Svergun, D.I., Metal-mediated self-assembly of a β-sandwich protein, Chemistry - A European Journal , 15, (46), 2009, p12672-12680
Downing, T., Lynn, D.J., Connell, S., Lloyd, A.T., Bhuiyan, A.K.F.H., Silva, P., Naqvi, A.N., (...), Bradley, D.G. , Erratum: Contrasting evolution of diversity at two disease-associated chicken genes (Immunogenetics DOI: 10.1007/s00251-009-0359-x), 2009, - 421-422
Onnis V, Kinsella GK, Carta G, Fayne D, Lloyd DG, Rational structure-based drug design and optimization in the ligand-binding domain of the glucocorticoid receptor-"., Future medicinal chemistry, 1, (2), 2009, p345-59
Immunomodulation by zwitterionic polysaccharides in, Microbial Glycobiology: Structure, Relevance and Applications, Elsevier, 2009, [McLoughlin RM, Kasper DL]
Ly NP, Ruiz-Perez B, McLoughlin RM, Visness CM, Wallace PK, Cruikshank WW, Tzianabos AO, O'Connor GT, Gold DR, Gern JE, Characterization of regulatory T cells in urban newborns., Clinical and molecular allergy : CMA, 7, 2009, p8
Waugh C., Sinclair LV., Finlay DK., Bayascas J., Cantrell DA., Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation, Molecular Cellular Biology, 29, (21), 2009, p5952 - 5962
Finlay DK., Sinclair LV., Fejoo C., Waugh C., Hagenbeek TJ., Spits H., Cantrell DA. , Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes, Journal of Experimental Medcine, 206, (11), 2009, p2441 - 2454
Cormican P, Lloyd AT, Downing T, Connell SJ, Bradley D, O'Farrelly C, The avian Toll-Like receptor pathway--subtle differences amidst general conformity., Developmental and comparative immunology, 33, (9), 2009, p967-73
Effects of pH on enzymes in, editor(s)D.L Purich , Enzyme Kinetics and Mechanism, New York, USA, Academic Pres, 2009, pp124 - 178, [Tipton, K.F., McDonald, A.G., Dixon, H.B.F.]
McDonald AG, Tipton KF, Boyce S, Tracing metabolic pathways from enzyme data., Biochimica et biophysica acta, 1794, (9), 2009, p1364-71
McDonald AG, Boyce S, Tipton KF, ExplorEnz: the primary source of the IUBMB enzyme list., Nucleic acids research, 37, (Database issue), 2009, pD593-7
Monoacylglycerols: The Workhorse Lipids for Crystallizing Membrane Proteins in Mesophases in, editor(s)Dale J. Benos; Sidney A. Simon , Current Topics in Membranes, San Diego, Elsevier, 2009, pp83-108 , [M. Caffrey, J. Lyons, T. Smyth and D.J. Hart]
Caffrey M, Cherezov V, Crystallizing membrane proteins using lipidic mesophases., Nature Protocols, 4, (5), 2009, p706-31
Caffrey M, Crystallizing membrane proteins for structure determination: use of lipidic mesophases., Annual Review of Biophysics, 38, 2009, p29-51
Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH, Alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding, Journal of Molecular Biology, 394, (5), 2009, p994 - 1010
Gattin Z, Riniker S, Hore PJ, Mok KH, van Gunsteren WF, Temperature and urea induced denaturation of the TRP-cage mini protein TC5b: A simulation study consistent with experimental observations, Protein Science, 18, (10), 2009, p2090 - 2099
Wilhelm K, Darinskas A, Noppe W, Duchardt E, Mok KH, Vukojević V, Schleucher J, Morozova-Roche LA, Protein oligomerization induced by oleic acid at the solid-liquid interface--equine lysozyme cytotoxic complexes, FEBS Journal, 276, (15), 2009, p3975 - 3989
Shun-ichiro Oda, Martina Schroder, Amir R. Khan, Structural Basis for Targeting of Human RNA Helicase DDX3 by Poxvirus Protein K7, Structure (Cell Press), 17, 2009, p1528 - 1537
Creagh EM, Brumatti G, Sheridan C, Duriez PJ, Taylor RC, Cullen SP, Adrain C, Martin SJ, Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival., PloS one, 4, (3), 2009, pe5055
Hayes, J.M. and Mantle, T.J., The effect of pH on the initial rate kinetics of the dimeric biliverdin-IXα reductase from the cyanobacterium Synechocystis PCC6803 , FEBS Journal, 276, 2009, p4414-4425
Franklin, E., Browne, S., Horan, A.E., Inomata,K., Hammam, M.A.S., Kinoshita, H., Lamparter,T., Golfis, G. and Mantle, T.J. , The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXα reductase and human biliverdin-IXβ reductase , FEBS Journal, 276, 2009, p4405-4413
Corr, S.C. and O'Neill, L.A.J. , Genetic Variation in Toll-Like Receptor Signalling and the Risk of Inflammatory and Immune Diseases, Journal of Innate Immunity, 1, (4), 2009, p350 - 357
Clive Holmes, Colm Cunningham, Elina Zotova, Jan Woolford, Christine Dean, Sara Kerr, David Culliford, and Hugh Perry, Systemic inflammation and disease progression in Alzheimer's disease, Neurology, 73, (10), 2009, p768 - 774
O'Neill LA, Boosting the brain's ability to block inflammation via microRNA-132., Immunity, 31, (6), 2009, p854-855
O'Neill LA, A feed-forward loop involving hyaluronic acid and toll-like receptor-4 as a treatment for colitis?, Gastroenterology., 137, (6), 2009, p1889-1891
McCormack WJ, Parker AE, O'Neill LA., Toll-like receptors and NOD-like receptors in rheumatic diseases., Arthritis Research & Therapy , 11, (5), 2009, p243
Carpenter S, Carlson T, Dellacasagrande J, Garcia A, Gibbons S, Hertzog P, Lyons A, Lin LL, Lynch M, Monie T, Murphy C, Seidl KJ, Wells C, Dunne A, O'Neill LA. , TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain., Journal of Immunology, 183, (6), 2009, p3989-3995
O'Neill LA., DNA makes RNA makes innate immunity, Cell, 138, (3), 2009, p428-430
Carpenter S, O'Neill LA , Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins., Biochemistry Journal, 422, (1), 2009, p1-10
Ferwerda B, Alonso S, Banahan K, McCall MB, Giamarellos-Bourboulis EJ, Ramakers BP, Mouktaroudi M, Fain PR, Izagirre N, Syafruddin D, Cristea T, Mockenhaupt FP, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Sundaresan S, Bedu-Addo G, van Crevel R, Hamann L, Oh DY, Schumann RR, Joosten LA, de la Rúa C, Sauerwein R, Drenth JP, Kullberg BJ, van der Ven AJ, Hill AV, Pickkers P, van der Meer JW, O'Neill LA, Netea MG., Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock, Proceedings of the National Academy of Science USA, 106, (25), 2009, p10272-10277
O'Neill LA, Bryant CE, Doyle SL, Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer., Pharmacological Reviews, 61, (2), 2009, p177-97
Corr SC, O'Neill LA, Listeria monocytogenes infection in the face of innate immunity., Cellular microbiology, 11, (5), 2009, p703 - 709
O'Neill LA, Regulation of signaling by non-degradative ubiquitination., The Journal of Biological Chemistry, 284, (13), 2009, p8209
Nomenclature and potential functions of copper amine oxidases. in, editor(s)G. Floris & B. Mondovi , Copper Amine Oxidases, Boca Raton, FL, USA , CRC Press, 2009, pp5 - 17, [S. Boyce, K.F. Tipton, M.I. O'Sullivan, G.P. Davey. M. Motherway Gildea, A.G. McDonald, A. Olivieri, and J. O'Sullivan]
McDonald AG, Tipton KF and Davey GP, Mathematical modelling of metabolism, The Biochemist, 31, 2009, p24 - 27
Black WJ, Stagos D, Marchitti SA, Nebert DW, Tipton KF, Bairoch A and Vasilio V., Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature., Pharmocogenetics and Genomica, 2009
Mills, K.H.G., Jarnicki, AJ, Toomey D, TCD, Compositions and methods for the treatment of cancer and infectious diseases, 2009, 12/085787
Mills, K.H.G. and Higgins, S., TCD, Compounds and methods for the treatment of autoimmune and inflammatory disorders, 2009, PCT/EP2009/067819
Downing T, Lynn DJ, Connell S, Lloyd AT, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, Hanotte O, O'Farrelly C, Bradley DG, Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus., BMC Evolutionary Biology, 9, 2009, part. no. 136
Downing T, Cormican P, O'Farrelly C, Bradley DG, Lloyd AT, Evidence of the adaptive evolution of immune genes in chicken, BMC Research Notes, 2, (254), 2009, part. no. 254
Diana Spitznagel, Charles Ebikeme, Marc Biran, Nóirín Nic a' Bháird, Frédéric Bringaud, Gary T. M. Henehan and Derek P. Nolan, Alanine aminotransferase of Trypanosoma brucei- a key role in proline metabolism in procyclic life forms, FEBS Journal, 276, (23), 2009, p7187 - 7199
Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin CP, Lloyd DG, Auld DS, Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries., Nature Biotechnology, 27, (11), 2009, p1050-5
Knox AJ, Price T, Pawlak M, Golfis G, Flood CT, Fayne D, Williams DC, Meegan MJ, Lloyd DG, Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin., Journal of medicinal chemistry, 52, (8), 2009, p2177-80
Lynch L, O'Shea D, Winter DC, Geoghegan J, Doherty DG, O'Farrelly C, Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity., European Journal of Immunology, 39, (7), 2009, p1893-1901
Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, Tubridy N and Mills KHG, CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis, Journal of Immunology, 183, 2009, p7602 - 7610
Dunne PJ, Moran B, Cummins RC and Mills KH , CD11c+CD8alpha+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis. , The Journal of Immunology, 183, 2009, p400 - 410
Mills KH, Dunne A, Immune modulation: IL-1, master mediator or initiator of inflammation, Nature Medicine, 15, (12), 2009, p1363-1364
Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM, A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4., The Journal of Nutrition, 139, (12), 2009, p2351-2357
Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, O'Farrelly C, Tubridy N, Mills KH, CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis., Journal of Immunology , 183, (11), 2009, p7602-7610
Becker CE, Creagh EM, O'Neill LA, Rab39a binds caspase-1 and is required for caspase-1-dependent il-1{beta} secretion, Journal of Biological Chemistry, 284, (50), 2009, p34531-34537
McElligott, AM, Maginn, EN, Greene, LM, McGuckin, S, Hayat, A, Browne, PV, Butini, S, Campiani, G, Catherwood, MA, Vandenberghe, E, Williams, DC, Zisterer, DM, Lawler, M, The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia., Cancer Research, 69, (21), 2009, p8366 - 8375
de Roos, B, Rungapamestry, V, Ross, K, Rucklidge, G, Reid, M, Duncan, G, Horgan, G, Toomey, S, Browne, J, Loscher, CE, Mills, KH, Roche, HM, Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet., Proteomics, 9, (12), 2009, p3244 - 3256
Walsh, KP, Brady, MT, Finlay, CM, Boon, L, Mills, KH, Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses., Journal of Immunology , 183, (3), 2009, p1577 - 1586
Oral delivery of vaccines in, editor(s)J Fix. and V H.L. Lee , Oral Peptide and Protein Drug Delivery, New York , Marcel Dekker, 2009, [Lavelle, E.C. and O'Hagan, D.T.]
Sutton, C.E., Lalor, S.J., Sweeney, C.M., Brereton, C.F., Lavelle, E.C. and Mills, K.H.G , Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity., Immunity, 31, (2), 2009, p331-341
Brereton CF, Sutton CE, Lalor SJ, Lavelle EC, Mills KH., Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease., Journal of Immunology, 183, (3), 2009, p1715-2173
Sharp, F., Ruane, D., Claas, B., Creagh, E., Harris, J., Malyala, P., Singh, M., O'Hagan, D.T., Pétrilli, V., Tschopp, J., O'Neill, L.A.J. and *Lavelle, E.C, Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome., Proceedings of the National Academy of Sciences of the U.S.A, 106, (3), 2009, p870-875
Alexander U. Lüthi, Sean P. Cullen, Edel A. McNeela, Patrick J. Duriez, Inna S. Afonina, Clare Sheridan, Gabriela Brumatti, Rebecca C. Taylor, Kristof Kersse, Peter Vandenabeele, Ed C. Lavelle, and Seamus J. Martin, Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases, Immunity, 31, (1), 2009, p84-98
Ronan G. Shaughnessy, Kieran G. Meade, Sarah Cahalane, Brenda Allan, Carla Reiman, John J. Callanan and Cliona O' Farrelly, Innate immune gene expression differentiates the early avian intestinal response between Salmonella and Campylobacter, Veterinary Immunology and Immunopathology, 132, (2-4), 2009, p191-198
McDonald, Andrew G., Tipton, Keith F. and Boyce, Sinéad, Tracing metabolic pathways from enzyme data , BBA - Proteins & Proteomics, 1794, (9), 2009, p1364-1371
Lyons, A, McQuillan, K, Deighan, BF, O'Reilly, JA, Downer, EJ, Murphy, AC, Watson, M, Piazza, A, O'Connell, F, Griffin, R, Mills, KH, Lynch, MA, Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide., Brain, Behavior, and Immunity, 23, (7), 2009, p1020 - 1027
Telford, JE, Kilbride SM and Davey GP, Complex I is rate limiting for oxygen consumption in the nerve terminal. , Journal Biological Chemistry, 284, 2009, p9109 - 9114
Thanavala,Y., Lavelle, EC. and Ogra,P. , All things mucosal, Expert Reviews in Vaccines , 8, (2), 2009, p139 - 142
Lavelle, E.C., Thanavala, J. and Ogra,P. , Mucosal immunity on the banks of the Duoro, Human Vaccines, 5, (5), 2009, p1 - 3
Harris, J., Hope, J. and Lavelle, E.C. , Autophagy and the immune response to TB, Transboundary and Emerging Diseases , 56, (6-7), 2009, p248-254
The role of NK cells in bacterial infection in, editor(s)Zimmer, J , Natural Killer cells - at the forefront of modern immunology, Springer, 2009, [McSharry, B and Gardiner, CM]
Day IJ, Maeda K, Paisley HJ, Mok KH, Hore PJ, Refolding of RNase A monitord by real-time photo-CIDNP NMR spectroscopy, Journal of Biomolecular NMR, 44, (2), 2009, p77 - 86
Bernard E, Parthsarathi L, Cho M-K, Aylward K, Raab M, Daxecker H, O'Dushlaine CT, Shields DC, Devocelle M, Keyes T, Cosgrave L, O'Neill S, Mok KH, Moran N, Ligand Switching in Cell-Permeable Peptides: Manipultation of the alpha integrin signature motif, ACS Chemical Biology, 4, (6), 2009, p457 - 471
Pettersson-Kastberg J, Aits S, Gustafsson L, Mossberg A-K, Storm P, Trulsson M, Persson F, Mok KH, Svanborg C, Can misfolded proteins be beneficial? The HAMLET case. (Review), Annals of Medicine, 41, (3), 2009, p162 - 176
N.M. Curtin, N.T. Boyle, K.H.G. Mills and T.J. Connor, Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide., Brain Behavior and Immunity, 23, 2009, p535 - 547
Mills, KH, Designer adjuvants for enhancing the efficacy of infectious disease and cancer vaccines based on suppression of regulatory T cell induction., Immunology letters, 122, (2), 2009, p108-111
Boland C, Hayes PA, Santa-Maria I, Nishimura S and Kelly VP, Queuosine formation in eukaryotic tRNA occurs via a mitochondrial localized heteromeric transglycoslase. , Journal of Biological Chemistry, 284, (27), 2009, p18218-18227
Orla Cunningham, Suzanne Campion, V Hugh Perry, Nicolai Sidenius, Fabian Docagne and Colm Cunningham, Microglia and the urokinase plasminogen activator receptor (uPAR) / uPA system in innate brain inflammation, GLIA, 57, (16), 2009, p1802 - 1814
Niaobh O'Donoghue, Trevor Sweeney, Robin Donagh, Kieran Clarke and Richard K. Porter , Control of Choline Oxidation in Rat Kidney Mitochondria, Biochimica Biophysica Acta (Bioenergetics), 1787, 2009, p1135 - 1139
Bright S.A., Greene, L.M., Greene, T.F., Campiani, G., Buitini, S., Brindisi, M., Lawler, M., Meegan, M.J., Williams, D.C. and Zisterer, D.M. , The novel pyrrolo-1,5-benzoxazepine, PBOX-21, potentiates the apoptotic efficacy of STI571 (imatinib mesylate) in human chronic myeloid leukaemia cells, Biochemical Pharmacology, 77, (3), 2009, p310-321
Bane, F.T., Pennington, S.R., Campiani, G., Williams, D.C., Zisterer, D.M. & Mc Gee, M.M. , The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells., Journal of Pharmacology and Experimental Therapeutics, 329, 2009, p38-47
Role of Toll-Like Receptors in the Innate Immune Response to RNA Viruses in, editor(s)Brasier, A.R. et al. , Cellular Signaling and Innate Immune Responses to RNA Virus Infections, ASM Press, 2009, [Keating, S.E. & Bowie A.G.]
Characterisation of viral proteins that inhibit TLR signal transduction in, editor(s)O'Neill, L.A.J and McCoy, C. , Toll-Like Receptors, Methods of Molecular Biology, Humana Press, 2009, [Stack, J & Bowie, A.G.]
Uncovering novel gene function in TLR signalling using siRNA in, editor(s)O'Neill, L.A.J and McCoy, C. , Toll-Like Receptors, Methods of Molecular Biology, Humana Press, 2009, [Carty, M., Keating, S. & Bowie, A.G. ]
Kalverda AP, Thompson GS, Vogel A, Schröder M, Bowie AG, Khan AR & Homans SW, Poxvirus K7 protein adopts a Bcl-2 fold: Biochemical mapping of its interactions with human DEAD box RNA helicase DDX3., Journal of Molecular Biology, 385, (3), 2009, p843-853
Recacha R, Boulet A, Jollivet F, Monier S, Houdusse A, Goud B & Khan AR , Structural basis for recruitment of Rab6-Interacting Protein 1 to Golgi via a RUN domain., Structure, 17, (1), 2009, p21-30
Nomenclature and Potential Functions of Copper Amine Oxidases in, editor(s)Giovanni Floris and Bruno Mondovi , Copper Amine Oxidases: Structures, Catalytic Mechanisms and Role in Pathophysiology, CRC Press, 2009, [S. Boyce, K. F. Tipton, M. I. O'Sullivan, G. P. Davey, M. Motherway Gildea, A. G. McDonald, A. Olivieri, and J. O'Sullivan]
Onnis V, Kinsella GK, Carta G, Fayne D, Lloyd DG., Rational ligand based drug design and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor á, Future Medicinal Chemistry, 1, (2), 2009, p345 - 359
O'Neill LAJ and McCoy C, Toll-like receptor protocols. Methods in Molecular Medicine Series, 517, New Jersey USA , Humana Press, 2009
Palsson-McDermott E, Doyle S, McGettrick A, Hardy M, Husebye H, Banahan K, Gong M, Golenbock , Espevik T and O'Neill LAJ, TAG: a GOLD domain-containing splice variant of TRAM that negatively regulates the MyD88-independent pathway in TLR4 signaling, Nature Immunology, 10, 2009, p579 - 586
Sheedy FJ, O'Neill LA., Adding fuel to fire: microRNAs as a new class of mediators of inflammation., Annals of the Rheumatic Diseases, 67 , (Suppl 3), 2009, piii50 - iii55
Freinbichler, W., Tipton, K.F., Della Corte, L. and Linert, W. , Mechanistic aspects of the Fenton reaction under conditions approximated to the extracellular fluid. , Journal of Inorganic Biochemistry, 103, (1), 2009, p28 - 34
Downing, T, Lynn, DJ, Connell, S, Lloyd, AT, Bhuiyan, AF, Silva, P, Naqvi, AN, Sanfo, R, Sow, RS, Podisi, B, O'Farrelly, C, Hanotte, O, Bradley, DG, Contrasting evolution of diversity at two disease-associated chicken genes., Immunogenetics, 61, (1), 2009, p303 - 314
Keating, SE, Bowie, AG, The role of non-degradative ubiquitination in interleukin-1 and Toll-like receptor signalling., The Journal of Biological Chemistry, 284, (13), 2009, p8211 - 8215
David J. Sanderson, Colm Cunningham, Robert, M.J. Deacon, David, M. Bannerman, V. Hugh Perry, & J. Nicholas P. Rawlins., A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning, Behavioural Brain Research, 201, (1), 2009, p103 - 111
N.M. Curtin, K.H.G. Mills and T.J. Connor, Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: Reversal by the anxiolytic chlordiazepoxide, Brain Behavior and Immunity, 23, (3), 2009, p371 - 379
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