Publications
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76 publications from 2022
Floudas A, Smith CM, Tynan O, Neto N, Krishna V, Wade SM, Hanlon M, Cunningham C, Marzaioli V, Canavan M, Fletcher JM, Mullan RH, Cole S, Hao LY, Monaghan MG, Nagpal S, Veale DJ, Fearon U., Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis., Annals of the rheumatic diseases, 2022, pannrheumdis-2021-221761
Al-Sayyar, A. and Hulme, K.D. and Thibaut, R. and Bayry, J. and Sheedy, F.J. and Short, K.R. and Alzaid, F., Respiratory Tract Infections in Diabetes â" Lessons From Tuberculosis and Influenza to Guide Understanding of COVID-19 Severity, Frontiers in Endocrinology, 13, (919223), 2022
Drakeford, C. and Aguila, S. and Roche, F. and Hokamp, K. and Fazavana, J. and Cervantes, M.P. and Curtis, A.M. and Hawerkamp, H.C. and Dhami, S.P.S. and Charles-Messance, H. and Hackett, E.E. and Chion, A. and Ward, S. and Ahmad, A. and Schoen, I. and Breen, E. and Keane, J. and Murphy, R. and Preston, R.J.S. and Oâ Sullivan, J.M. and Sheedy, F.J. and Fallon, P. and Oâ Donnell, J.S., von Willebrand factor links primary hemostasis to innate immunity, Nature Communications, 13, (1), 2022
Toller-Kawahisa, J.E. and O'Neill, L.A.J., How neutrophil metabolism affects bacterial killing, Open Biology, 12, (11), 2022
Paolicelli, R.C. and Sierra, A. and Stevens, B. and Tremblay, M.-E. and Aguzzi, A. and Ajami, B. and Amit, I. and Audinat, E. and Bechmann, I. and Bennett, M. and Bennett, F. and Bessis, A. and Biber, K. and Bilbo, S. and Blurton-Jones, M. and Boddeke, E. and Brites, D. and BrÎne, B. and Brown, G.C. and Butovsky, O. and Carson, M.J. and Castellano, B. and Colonna, M. and Cowley, S.A. and Cunningham, C. and Davalos, D. and De Jager, P.L. and de Strooper, B. and Denes, A. and Eggen, B.J.L. and Eyo, U. and Galea, E. and Garel, S. and Ginhoux, F. and Glass, C.K. and Gokce, O. and Gomez-Nicola, D. and González, B. and Gordon, S. and Graeber, M.B. and Greenhalgh, A.D. and Gressens, P. and Greter, M. and Gutmann, D.H. and Haass, C. and Heneka, M.T. and Heppner, F.L. and Hong, S. and Hume, D.A. and Jung, S. and Kettenmann, H. and Kipnis, J. and Koyama, R. and Lemke, G. and Lynch, M. and Majewska, A. and Malcangio, M. and Malm, T. and Mancuso, R. and Masuda, T. and Matteoli, M. and McColl, B.W. and Miron, V.E. and Molofsky, A.V. and Monje, M. and Mracsko, E. and Nadjar, A. and Neher, J.J. and Neniskyte, U. and Neumann, H. and Noda, M. and Peng, B. and Peri, F. and Perry, V.H. and Popovich, P.G. and Pridans, C. and Priller, J. and Prinz, M. and Ragozzino, D. and Ransohoff, R.M. and Salter, M.W. and Schaefer, A. and Schafer, D.P. and Schwartz, M. and Simons, M. and Smith, C.J. and Streit, W.J. and Tay, T.L. and Tsai, L.-H. and Verkhratsky, A. and von Bernhardi, R. and Wake, H. and Wittamer, V. and Wolf, S.A. and Wu, L.-J. and Wyss-Coray, T., Microglia states and nomenclature: A field at its crossroads, Neuron, 110, (21), 2022, p3458-3483
Sullivan, G.P. and Davidovich, P. and Muñoz-Wolf, N. and Ward, R.W. and Hernandez Santana, Y.E. and Clancy, D.M. and Gorman, A. and Najda, Z. and Turk, B. and Walsh, P.T. and Lavelle, E.C. and Martin, S.J., Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement, Science immunology, 7, (78), 2022, peade5728
Richard Porter, A Role for Cannabinoids in Preventing Cachexia in an in vitro Human Muscle Cell Model, Drug Repurposing II,, London, Feb 2022, 2022, UK Biochemical Society
ZQ Ge, RK Porter, MF Rooney , COMPARASION OF PHENOTYPES ASSOCIATED WITH A HIGHLY INVASIVE TRIPLE-NEGATIVE BREAST CANCER (TNBC) CELL LINE AND ITS PARENTAL COUNTERPART , 12th International Cancer Conference 2022 Meeting Abstracts, 12th International Cancer Conference 2022 , TBSI, Oct 2022, 2022
Maloney BT, Kubisztal M, Karavyraki M, Rooney MF, Knox A and Porter RK, The Potential of Nicotinamide N-Methyltransferase (NNMT) as an Anti-Cancer Target in Cultured Human Oral Squamous Cancer Cells (OSCC), Irish Association of Dental Research (IADR) Conference, IADR International Division Meeting Abstract, Irish Association of Dental Research (IADR) Conference, IADR International Division, Chengdu, China, June 2022, 2022
Mallon PW, Horgan M, McAloon CG, Lunn PD, Little J, Beck A, Bennett A, Shaver N, Conway A, O'Regan R, Whelan B, Rapid Testing Expert Advisory Group, Ireland, Members of the Rapid Testing Expert Advisory Group., Development of a risk assessment profile tool to determine appropriate use of SARS-CoV-2 rapid antigen detection tests for different activities and events in Ireland, since October 2021., Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 27, (3), 2022
Cervantes-Silva MP, Carroll RG, Wilk MM, Moreira D, Payet CA, O'Siorain JR, Cox SL, Fagan LE, Klavina PA, He Y, Drewinski T, McGinley A, Buel SM, Timmons GA, Early JO, Preston RJS, Hurley JM, Finlay DK, Schoen I, Javier Sánchez-García F, Mills KHG, Curtis AM., The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing., Nature communications, 13, (1), 2022, p7217
Campiani, G., Khan, T., Ulivieri, C., Staiano, L., Papulino, C., Magnano, S., Nathwani, S., Ramunno, A., Lucena-Agell, D., Relitti, N. and Federico, S., Pozzetti, L., Carullo, G., Casagni, A., Brogi, S., Vanni, F., Galatello, P., Ghanim, M., McCabe, N., Lamponi, S., Valoti, M., Ibrahim, O., O'Sullivan, J., Turkington, R., Kelly, V.P., VanWemmel, R., Fernando Díaz, J., Gemma, S., Zisterer, D., Altucci, L., De Matteis, A., Butini, S., Benedetti, R., Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy, European Journal of Medicinal Chemistry, 235, 2022, p114274-
Eavan C. McLoughlin, Patricia Hannon Barroeta, Daniela M. Zisterer, and Niamh M. O'Boyle, P41: A comparison of chiral diastereomeric versus kinetic enzymatic resolution for enantioseparation of microtubule depolymerising beta-lactams, 30th Annual GP2A Medicinal Chemistry Conference, Dublin, 24-26 August 2022, 2022
Singh S, O'Reilly S, Gewaid H, Bowie AG, Gautier V, Worrall DM., Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication., International journal of molecular sciences, 23, (20), 2022, p12522
Richard K. Porter, Is there a role for Interleukin-6 (IL-6) in Cancer Metabolism? - Evidence of a role for Interleukin-6 in anoikis resistance and bioenergetic programming in oral squamous cell carcinoma, European Society of Clinical Investigation (ESCI), Bari, Italy., June, 2022, Piero Portincasa
Richard K. Porter, A comparison of bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells, Bioblast 2022: BEC Inaugural Conference, Innsbruck, Austria, June, 2022, Erich Gnaiger
Salma Mohammed Ajahdali , Modulation of hepatic autophagy for therapeutic correction of type 2 diabetes, Trinity College Dublin, 2022
John Noone, Marilena Karavyraki, Mary F. Rooney, Andrew Yates, Saoirse E. O'Sullivan, Richard K. Porter., A Role for Cannabinoids in Preventing Cachexia in an in vitro Human Muscle Cell Model., https://www.eventsforce.net/biochemsoc/frontend/reg/absViewDocumentFE.csp?documentID=3539&eventID=130, Drug Repurposing II, London, May 2022, edited by UK Biochemical Society , 2022
Mary Rooney, Nuno Neto, Michael Monaghan, Emmeline Hill, Richard K. Porter, Conditionally immortalised equine skeletal muscle cell lines for in vitro analysis, Biochemistry and Biophysics Reports, 2022
Marilena Karavyraki, Erich Gnaiger, Richard K. Porter, Bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells, Bioenergetics Communications (BEC), (2022), 2022
Herrera-Uribe J, Naylor P, Rajab E Coskuner G, Jassim MS Jassim, Al-Qahtani M & Stevenson NJ., Long term detection and quantification of SARS-CoV-2 RNA in wastewater in Bahrain., Journal of Hazardous Material Advances, 7, 2022, p1 - 9, p1-9
David Finlay, Amino acid regulation natural conventional DC Function , Gordon Conference on "Immunometabolism in Health and Disease", Bryant University, Rhode Island, USA, June 19th -24th, 2022
David Finlay, QUAS-R: Glutamine (Q) Uptake Assay with Single cell Resolution reveals metabolic heterogeneity with immune populations, Cytometry Society of Ireland annual conference, Dublin, Ireland, 25th October, 2022, Cytometry Society of Ireland
David Finlay, Fuels that drive your CARs! Optimizing NK cell metabolism for cellular therapies, Company seminar series, Online, 3rd June, 2022, Takeda Pharmaceutical Company Limited
David Finlay, Nutrients and metabolites controlling NK cell responses, Institutional seminar series, online, 26nd February, 2022, Karolinska institutet
David Finlay, Nutrient transport and anti-tumour NK cell responses, 19th Meeting of the society for natural immunity (NK2022), Florida, USA, 14th May, 2022, Society for natural immunity
Leonard R. Pelgrom, Gavin Davis, Simon O'Shaughnessy, Sander Van Kasteren, David Finlay, Linda V. Sinclair, QUAS-R: Glutamine (Q) Uptake Assay with Single cell Resolution reveals metabolic heterogeneity with immune populations. , BioRxiv, 2022
Alejandro J Brenes, Jens L Hukelmann, Laura Spinelli, Andrew JM Howden, Julia M Marchingo, Linda V Sinclair, Christina Rollings, Olivia J James, Iain R Phair, Stephen P Matthews, Sarah H Ross, Simon C Arthur, Mahima Swamy, David K Finlay, Angus L Lamond, Doreen A Cantrell, Immunological Proteome Resource, BioRxiv, 2022
Currivan, E., Finlay, DK., Moreira, D., Dendritic cells metabolism: a strategic path to improve antitumoral DC vaccination, Clinical and experimental immunology, 208, (2), 2022, p1993 - 2001
Farid, E. and Herrera-Uribe, J. and Stevenson, N.J., The Effect of Age, Gender and Comorbidities Upon SARS-CoV-2 Spike Antibody Induction After Two Doses of Sinopharm Vaccine and the Effect of a Pfizer/BioNtech Booster Vaccine, Frontiers in Immunology, 13, (817597), 2022
Tsui, A. and Searle, S.D. and Bowden, H. and Hoffmann, K. and Hornby, J. and Goslett, A. and Weston-Clarke, M. and Hamill Howes, L. and Street, R. and Perera, R. and Taee, K. and Kustermann, C. and Chitalu, P. and Razavi, B. and Magni, F. and Das, D. and Kim, S. and Chaturvedi, N. and Sampson, E.L. and Rockwood, K. and Cunningham, C. and Ely, E.W. and Richardson, S.J. and Brayne, C. and Muniz Terrera, G. and Tieges, Z. and MacLullich, A. and Davis, D., The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study, The Lancet Healthy Longevity, 3, (4), 2022, pe232-e241
Guy, C. and Bowie, A.G., Recent insights into innate immune nucleic acid sensing during viral infection, Current Opinion in Immunology, 78, (102250), 2022
Coyle, R. and O'Sullivan, M.J. and Zisterer, D.M., Targeting inhibitor of apoptosis proteins (IAPs) with IAP inhibitors sensitises malignant rhabdoid tumour cells to cisplatin, Cancer Treatment and Research Communications, 32, (100579), 2022
Hannon Barroeta, P. and Magnano, S. and O'Sullivan, M.J. and Zisterer, D.M., Evaluation of targeting autophagy for the treatment of malignant rhabdoid tumours, Cancer Treatment and Research Communications, 32, (100584), 2022
McCabe, N.H. and Stevenson, L. and Scanlon, E. and Douglas, R. and Kennedy, S. and Keminer, O. and WindshÃŒgel, B. and Zisterer, D. and Kennedy, R.D. and Blayney, J.K. and Turkington, R.C., Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches, Cancers, 14, (15), 2022
McKenna, E. and Wubben, R. and Isaza-Correa, J.M. and Melo, A.M. and Mhaonaigh, A.U. and Conlon, N. and Oâ Donnell, J.S. and NÃ Cheallaigh, C. and Hurley, T. and Stevenson, N.J. and Little, M.A. and Molloy, E.J., Neutrophils in COVID-19: Not Innocent Bystanders, Frontiers in Immunology, 13, (864387), 2022
McGettrick, A.F. and Oâ Neill, L.A.J., The itaconate family of immunomodulators grows, Nature Metabolism, 4, (5), 2022, p499-500
Ryan, T.A.J. and O'Neill, L.A.J., Innate immune signaling and immunothrombosis: New insights and therapeutic opportunities, European Journal of Immunology, 52, (7), 2022, p1024-1034
Weiss, H.J. and Oâ Neill, L.A.J., Of Flies and Menâ"The Discovery of TLRs, Cells, 11, (19), 2022
Turley, J.L. and Lavelle, E.C., Resolving adjuvant mode of action to enhance vaccine efficacy, Current Opinion in Immunology, 77, (102229), 2022
Mills, K.H.G., Innate lymphoid cells recruit T cells to turn up the heat on tumors, Cancer Cell, 40, (4), 2022, p362-364
McDonald AG, Tipton KF., Enzyme nomenclature and classification: the state of the art, FEBS Journal, (Jan), 2022, pfebs.16274
McDonald A.G., Tipton K.F., Parameter reliability and understanding enzyme function, Molecules, 27, (1), 2022, p263
O-Glycologue: A Formal-Language-Based Generator of O-Glycosylation Networks in, editor(s)Davey, G.P. , Glycosyltion, New York, Humana, 2022, pp223 - 236, [McDonald A.G., Davey G.P.]
Vincent P. Kelly, RNA modifications as targets for autoimmunity , RNA Associated Mechanism Conference: In Immunity and Disease, Steamboat Colorado, 28th Aug - 1st Sept , 2022, Uttiya Basa, Vincent Kelly, Nina Papvasilou, Jayantha Chaudhuri
Malebari AM, Duffy Morales G, Twamley B, Fayne D, Khan MF, McLoughlin EC, O'Boyle NM, Zisterer DM, Meegan MJ., Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones., Pharmaceuticals (Basel, Switzerland), 15, (9), 2022, p1044
Benevenuto SGM, Domenico MD, Yariwake VY, Dias CT, Mendes-da-Silva C, Alves NO, Caumo SEDS, Vasconcellos P, Morais DR, Cardoso MS, Ianicelli J, Waked D, Davey GP, Boylan F, Costa JL, Veras MM., Prenatal exposure to Cannabis smoke induces early and lasting damage to the brain., Neurochemistry International, 160, 2022
McDonald AG, Mariethoz J, Davey GP, Lisacek F., In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesis., Scientific Reports, 27, (12(1)), 2022, p10846-
Hooftman, A. and O'Neill, L.A.J., Nanoparticle asymmetry shapes an immune response, Nature, 601, (7893), 2022, p323-325
Baldanti, F. and Ganguly, N.K. and Wang, G. and Möckel, M. and Oâ Neill, L.A. and Renz, H. and dos Santos Ferreira, C.E. and Tateda, K. and Van Der Pol, B., Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future, Critical Reviews in Clinical Laboratory Sciences, 2022
Toller-Kawahisa, J.E. and Oâ Neill, L.A.J., Creating ATP via creatine kinase B for NLRP3 activation, Nature Immunology, 2022
Peace, C.G. and Oâ Neill, L.A.J., The role of itaconate in host defense and inflammation, Journal of Clinical Investigation, 132, (2), 2022
Ryan, D.G. and Knatko, E.V. and Casey, A.M. and Hukelmann, J.L. and Dayalan Naidu, S. and Brenes, A.J. and Ekkunagul, T. and Baker, C. and Higgins, M. and Tronci, L. and Nikitopolou, E. and Honda, T. and Hartley, R.C. and O'Neill, L.A.J. and Frezza, C. and Lamond, A.I. and Abramov, A.Y. and Arthur, J.S.C. and Cantrell, D.A. and Murphy, M.P. and Dinkova-Kostova, A.T., Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response, iScience, 25, (2), 2022
Runtsch, M.C. and Angiari, S. and Hooftman, A. and Wadhwa, R. and Zhang, Y. and Zheng, Y. and Spina, J.S. and Ruzek, M.C. and Argiriadi, M.A. and McGettrick, A.F. and Mendez, R.S. and Zotta, A. and Peace, C.G. and Walsh, A. and Chirillo, R. and Hams, E. and Fallon, P.G. and Jayamaran, R. and Dua, K. and Brown, A.C. and Kim, R.Y. and Horvat, J.C. and Hansbro, P.M. and Wang, C. and O'Neill, L.A.J., Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages, Cell Metabolism, 34, (3), 2022, p487-501.e8
Ryan, T.A.J. and Preston, R.J.S. and Oâ Neill, L.A.J., Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants, Biochemical Journal, 479, (6), 2022, p731-750
Pinkerton, J.W. and Kim, R.Y. and Brown, A.C. and Rae, B.E. and Donovan, C. and Mayall, J.R. and Carroll, O.R. and Khadem Ali, M. and Scott, H.A. and Berthon, B.S. and Baines, K.J. and Starkey, M.R. and Kermani, N.Z. and Guo, Y.-K. and Robertson, A.A.B. and O'Neill, L.A.J. and Adcock, I.M. and Cooper, M.A. and Gibson, P.G. and Wood, L.G. and Hansbro, P.M. and Horvat, J.C., Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma, Journal of Allergy and Clinical Immunology, 149, (4), 2022, p1270-1280
Campiani, G. and Khan, T. and Ulivieri, C. and Staiano, L. and Papulino, C. and Magnano, S. and Nathwani, S. and Ramunno, A. and Lucena-Agell, D. and Relitti, N. and Federico, S. and Pozzetti, L. and Carullo, G. and Casagni, A. and Brogi, S. and Vanni, F. and Galatello, P. and Ghanim, M. and McCabe, N. and Lamponi, S. and Valoti, M. and Ibrahim, O. and O'Sullivan, J. and Turkington, R. and Kelly, V.P. and VanWemmel, R. and DÃaz, J.F. and Gemma, S. and Zisterer, D. and Altucci, L. and De Matteis, A. and Butini, S. and Benedetti, R., Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy, European Journal of Medicinal Chemistry, 235, (114274), 2022
Williams, N.C. and Ryan, D.G. and Costa, A.S.H. and Mills, E.L. and Jedrychowski, M.P. and Cloonan, S.M. and Frezza, C. and O'Neill, L.A., Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages, Journal of Biological Chemistry, 298, (2), 2022
Gibbons, L. and Ozaki, E. and Greene, C. and Trappe, A. and Carty, M. and Coppinger, J.A. and Bowie, A.G. and Campbell, M. and Doyle, S.L., SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration, Frontiers in Neuroscience, 16, (852114), 2022
Wahaab, A. and Mustafa, B.E. and Hameed, M. and Stevenson, N.J. and Anwar, M.N. and Liu, K. and Wei, J. and Qiu, Y. and Ma, Z., Potential role of flavivirus ns2b-ns3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: A review, Viruses, 14, (1), 2022
Zhang, Y. and Gargan, S. and Roche, F.M. and Frieman, M. and Stevenson, N.J., Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells, Viruses, 14, (4), 2022
Mannion JM, McLoughlin RM, Lalor SJ, The Airway Microbiome-IL-17 Axis: a Critical Regulator of Chronic Inflammatory Disease, Clinical Reviews in Allergy & Immunology,, March 11, 2022
Cooper AJR, Clegg J, Cassidy FC, Hogan AE, McLoughlin RM., Human MAIT Cells Respond to Staphylococcus aureus with Enhanced Anti-Bacterial Activity., Microorganisms, 10, (1), 2022
Marilena Karavyraki, Richard K. Porter, Evidence of a role for interleukin-6 in anoikis resistance in oral squamous cell carcinoma., Medical Oncology, 39, 2022, p60-
Hyesoo Jeon and Jerrard M. Hayes and K. H. Mok, In Silico Analysis of Therapeutic Antibody Aggregation and the Influence of Glycosylation, Glycosylation, 2022, p169--183
Hough, K. and Verschuur, C.A. and Cunningham, C. and Newman, T.A., Macrophages in the cochlea; an immunological link between risk factors and progressive hearing loss, GLIA, 70, (2), 2022, p219-238
McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG, Fallon PG, Maher TM, Hogaboam CM, Molyneaux PL, Hirani N, Armstrong ME, Donnelly SC., Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis., American journal of respiratory and critical care medicine, 2022
Marzaioli V, Canavan M, Floudas A, Flynn K, Mullan R, Veale DJ, Fearon U., CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting., Frontiers in Immunology, 2022
McDonnell, C.M. and Ghanim, M. and Mike Southern, J. and Kelly, V.P. and Connon, S.J., De-novo designed β-lysine derivatives can both augment and diminish the proliferation rates of E. coli through the action of Elongation Factor P, Bioorganic and Medicinal Chemistry Letters, 59, (128545), 2022
Claudia Feriotti, Joana Sa-Pessoa, Ricardo Calderon-Gonzalez, Lili Gu, Brenda Morris, Ryoichi Sugisawa, Jose L Insua, Michael Carty, Amy Dumigan, Rebecca J Ingram, Adrien Kissenpfening, Andrew G Bowie, Jose A Bengoechea, Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity., Cell Reports, 40, (6), 2022, p111167-
Laura K Finnegan, Naomi Chadderton, Paul F Kenna, Arpad Palfi, Michael Carty, Andrew G Bowie, Sophia Millington-Ward, Gwyneth Jane Farrar, SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration, International Journal of Molecular Sciences, 2022
Ryan, L. and Mills, K.H.G., Sex differences regulate immune responses in experimental autoimmune encephalomyelitis and multiple sclerosis, European Journal of Immunology, 52, (1), 2022, p24-33
Fitzgerald, H.K.; O'Rourke, S.A.; Desmond, E.; Neto, N.G.B.; Monaghan, M.G.; Tosetto, M.; Doherty, J.; Ryan, E.J.; Doherty, G.A.; Nolan, D.P.; Fletcher, J.M.; Dunne, A, The Trypanosoma brucei-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells, Antioxidants, 11, 2022, p164-
Lynch RI, Lavelle EC., Immuno-modulatory biomaterials as anti-inflammatory therapeutics., Biochemical pharmacology, 197, 2022, p114890
Rebecca Amet, Viola Previtali, Helene B. Mihigo, Emily Sheridan, Sarah Brophy , Nadhim Kamil Hante, Maria Jose Santos-Martinez, Patrick J. Hayden, Paul V. Browne, Isabel Rozas, Anthony M. McElligott , Daniela M. Zisterer , A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma , Life Sciences, 290, 2022
Townsend L, Dyer AH, Naughton A, Imangaliyev S, Dunne J, Kiersey R, Holden D, Mooney A, Leavy D, Ridge K, Sugrue J, Aldoseri M, Kelliher JH, Ní Cheallaigh C, Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression, Heliyon, 8, (4), 2022, pe09230 - e09236