Publications
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110 publications from 2021
MacMahon Copas AN, McComish SF, Fletcher JM, Caldwell MA., The Pathogenesis of Parkinson's Disease: A Complex Interplay Between Astrocytes, Microglia, and T Lymphocytes?, Frontiers in neurology, 12, 2021, p666737
Kirby B, Fletcher JM., Mechanism of action of dimethyl fumarate: a small molecule with big effects., The British journal of dermatology, 185, (3), 2021, p483-484
Dieter Waschbuesch, Elena Purlyte, Amir R Khan, Dual arginine recognition of LRRK2 phosphorylated Rab GTPases, Biophysical Journal, 120, (9), 2021, p1846 - 1855
Dieter Waschbuesch, Kerryn Berndsen, Pawel Lis, Axel Knebel, Yuko PY Lam, Dario R Alessi & Amir R Khan, Structural basis for the specificity of PPM1H phosphatase for Rab GTPases, EMBO reports, 22: e52675, 2021, p10.15252/embr.202152675
O'Brien, K.L. and Assmann, N. and O'Connor, E. and Keane, C. and Walls, J. and Choi, C. and Oefner, P.J. and Gardiner, C.M. and Dettmer, K. and Finlay, D.K., De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells, European Journal of Immunology, 51, (1), 2021, p91-102
Slattery, K. and Woods, E. and Zaiatz-Bittencourt, V. and Marks, S. and Chew, S. and Conroy, M. and Goggin, C. and Maceochagain, C. and Kennedy, J. and Lucas, S. and Finlay, D.K. and Gardiner, C.M., TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer, Journal for ImmunoTherapy of Cancer, 9, (2), 2021
Gleeson, L.E. and Roche, H.M. and Sheedy, F.J., Obesity, COVID-19 and innate immunometabolism, British Journal of Nutrition, 125, (6), 2021, p628-632
Jones, S.A. and Bryant, C. and Lloyd, C.M. and Mcinnes, I. and O'neill, L., A Vision for Cytokine Biology with 20/20 Clarity, Function, 2, (1), 2021
Richard Porter, Targeting Bioenergetics in Cancer, Trinity St. James Cancer Institute (TSJCI) Cancer Research Seminarses, online, May 2021, 2021
Maloney BT, Kubisztal M, Karavyraki M, Rooney MF, Knox A and Porter RK, The Potential of Nicotinamide N-Methyltransferase (NNMT) as an Anti-Cancer Target in Cultured Human Oral Squamous Cancer Cells (OSCC)., European Dental Students Association Meeting Abstracts, European Dental Students Association, online, Sept 2021, 2021
Maloney BT, Kubisztal M, Karavyraki M, Rooney MF, Knox A and Porter RK, The Potential of Nicotinamide N-Methyltransferase (NNMT) as an Anti-Cancer Target in Cultured Human Oral Squamous Cancer Cells (OSCC), Royal Academy of Medicine Ireland (RAMI) Meeting Abstracts, Royal Academy of Medicine Ireland (RAMI), Dublin, Dec 2021, 2021
Maloney BT, Kubisztal M, Karavyraki M, Rooney MF, Knox A and Porter RK, The Potential of Nicotinamide N-Methyltransferase (NNMT) as an Anti-Cancer Target in Cultured Human Oral Squamous Cancer Cells (OSCC)., Irish Association of Dental Research (IADR) Conference Abstracts, Irish Association of Dental Research (IADR) Conference, Belfast UK, Oct 2021 , 2021
Viviana Marzaioli, Mary Canavan, Alex Donnolly, Siobhan Wade, Alexander Fraser, Tim O'Sullivan, Sinead Harney, Arthritis Ireland, Douglas J. Veale, Ursula Fearon, Knowledge of disease, diagnosis, adherence and impact of research in an Irish cohort of patients with inflammatory arthritis, HRB Open Research, 4, 2021, p60
Canavan M, Marzaioli V, Bhargava V, Nagpal S, Gallagher P, Hurson C, Mullan R, Veale DJ, Fearon U, Functionally Mature CD1c+ Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium., Frontiers in immunology, 2021
Divangahi, M. and Aaby, P. and Khader, S.A. and Barreiro, L.B. and Bekkering, S. and Chavakis, T. and van Crevel, R. and Curtis, N. and DiNardo, A.R. and Dominguez-Andres, J. and Duivenwoorden, R. and Fanucchi, S. and Fayad, Z. and Fuchs, E. and Hamon, M. and Jeffrey, K.L. and Khan, N. and Joosten, L.A.B. and Kaufmann, E. and Latz, E. and Matarese, G. and van der Meer, J.W.M. and Mhlanga, M. and Moorlag, S.J.C.F.M. and Mulder, W.J.M. and Naik, S. and Novakovic, B. and Oâ Neill, L. and Ochando, J. and Ozato, K. and Riksen, N.P. and Sauerwein, R. and Sherwood, E.R. and Schlitzer, A. and Schultze, J.L. and Sieweke, M.H. and Benn, C.S. and Stunnenberg, H. and Sun, J. and van de Veerdonk, F.L. and Weis, S. and Williams, D.L. and Xavier, R. and Netea, M.G., Trained immunity, tolerance, priming and differentiation: distinct immunological processes, Nature Immunology, 22, (1), 2021, p2-6
Hooftman, A. and O'Neill, L.A.J., Can NLRP3 inhibitors improve on dexamethasone for the treatment of COVID-19?, Current Research in Pharmacology and Drug Discovery, 2, (100048), 2021
Peace, C.G. and O'Neill, L.A.J., Ironing Out Vaccine Efficacy, Med, 2, (2), 2021, p113-114
Day, E.A. and Oâ Neill, L.A.J., Targeting mitochondria to beat HIV-1, Nature Immunology, 22, (4), 2021, p398-399
Tummala, P. and Rooke, M. and Dahlstrom, J.E. and Takahashi, S. and Casarotto, M.G. and Fernando, N. and Hughes, M.M. and O'neill, L.A.J. and Board, P.G., Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation, Carcinogenesis, 42, (6), 2021, p853-863
Divangahi, M. and Aaby, P. and Khader, S.A. and Barreiro, L.B. and Bekkering, S. and Chavakis, T. and van Crevel, R. and Curtis, N. and DiNardo, A.R. and Dominguez-Andres, J. and Duivenvoorden, R. and Fanucchi, S. and Fayad, Z. and Fuchs, E. and Hamon, M. and Jeffrey, K.L. and Khan, N. and Joosten, L.A.B. and Kaufmann, E. and Latz, E. and Matarese, G. and van der Meer, J.W.M. and Mhlanga, M. and Moorlag, S.J.C.F.M. and Mulder, W.J.M. and Naik, S. and Novakovic, B. and Oâ Neill, L. and Ochando, J. and Ozato, K. and Riksen, N.P. and Sauerwein, R. and Sherwood, E.R. and Schlitzer, A. and Schultze, J.L. and Sieweke, M.H. and Benn, C.S. and Stunnenberg, H. and Sun, J. and van de Veerdonk, F.L. and Weis, S. and Williams, D.L. and Xavier, R. and Netea, M.G., Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (Nature Immunology, (2021), 22, 1, (2-6), 10.1038/s41590-020-00845-6), Nature Immunology, 22, (7), 2021, p928
Zotta, A. and Hooftman, A. and Oâ Neill, L.A.J., SARS-CoV-2 targets MAVS for immune evasion, Nature Cell Biology, 23, (7), 2021, p682-683
Buckley, C.D. and Chernajovsky, L. and Chernajovsky, Y. and Modis, L.K. and Oâ Neill, L.A. and Brown, D. and Connor, R. and Coutts, D. and Waterman, E.A. and Tak, P.P., Immune-mediated inflammation across disease boundaries: breaking down research silos, Nature Immunology, 22, (11), 2021, p1344-1348
Santarsiero, A. and Convertini, P. and Todisco, S. and Pierri, C.L. and De Grassi, A. and Williams, N.C. and Iacobazzi, D. and De Stefano, G. and Oâ Neill, L.A.J. and Infantino, V., ACLY nuclear translocation in human macrophages drives proinflammatory gene expression by NF-κB acetylation, Cells, 10, (11), 2021
Diskin, C. and Corcoran, S.E. and Tyrrell, V.J. and McGettrick, A.F. and Zaslona, Z. and O'Donnell, V.B. and Nolan, D.P. and O'Neill, L.A.J., The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2, Journal of immunology (Baltimore, Md. : 1950), 207, (10), 2021, p2551-2560
Diskin, C. and Zotta, A. and Corcoran, S.E. and Tyrrell, V.J. and Zaslona, Z. and O'Donnell, V.B. and O'Neill, L.A.J., 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages, Journal of immunology (Baltimore, Md. : 1950), 207, (10), 2021, p2561-2569
Umar, S. and Palasiewicz, K. and Volin, M.V. and Romay, B. and Rahat, R. and Tetali, C. and Arami, S. and Guma, M. and Ascoli, C. and Sweiss, N. and Zomorrodi, R.K. and Oâ Neill, L.A.J. and Shahrara, S., Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types, Cellular and Molecular Life Sciences, 78, (23), 2021, p7693-7707
Yin, M. and Oâ Neill, L.A.J., The role of the electron transport chain in immunity, FASEB Journal, 35, (12), 2021
Vanni, F. and Lopresti, L. and Zurli, V. and Kabanova, A. and Cattaneo, F. and Sicuranza, A. and Gozzetti, A. and Gemma, S. and Zisterer, D.M. and Bocchia, M. and Campiani, G. and Baldari, C.T. and Butini, S. and Ulivieri, C., A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in EΌ-TCL1 mice through the JNK/STAT4/p66Shc axis, Pharmacological Research, 174, (105965), 2021
McKenna, C. and Keogh, K. and Porter, R.K. and Waters, S.M. and Cormican, P. and Kenny, D.A., An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake, Scientific reports, 11, (1), 2021, p8942
The interplay between the immune system and viruses in, 2021, pp1-15 , [Wubben, R. and Efstathiou, C. and Stevenson, N.J.]
Zhang, Y. and Gargan, S. and Lu, Y. and Stevenson, N.J., An overview of current knowledge of deadly covs and their interface with innate immunity, Viruses, 13, (4), 2021
Almadhi, M.A. and Abdulrahman, A. and Sharaf, S.A. and AlSaad, D. and Stevenson, N.J. and Atkin, S.L. and AlQahtani, M.M., The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19, International Journal of Infectious Diseases, 105, 2021, p656-661
Gargan, S. and Stevenson, N.J., Unravelling the immunomodulatory effects of viral ion channels, towards the treatment of disease, Viruses, 13, (11), 2021
Alqahtani, M. and Mallah, S.I. and Stevenson, N. and Doherty, S., Vaccine trials during a pandemic: potential approaches to ethical dilemmas, Trials, 22, (1), 2021
E. Flis, G. Barber, C. Nulty, B. Keogh, P. McGuirk, A. Anand, J. O'Sullivan, M. Quante, E.M. Creagh. , Identification of TLR2 signalling mechanisms which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression, Cancers (Basel) , 13, (9), 2021, p2065 - 2081
Sherlock, L. and Mok, K. H., Metabolomics and Its Applications to Personalized Medicine, EKC 2019 Conference Proceedings, EKC 2019, Vienna, Austria, 2019, edited by Park, J. M. and Whang, D. R. , Springer Nature Singapore Pte Ltd, 2021, pp25 - 42
James C.S. Ho and Ines Ambite and K. H. Mok and Marek Babjuk and Catharina Svanborg, A scientific journey from discovery to validation of efficacy in cancer patients: HAMLET and alpha1-oleate, Molecular & Cellular Oncology, 8, (5), 2021
Anton{\'{\i, Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex, Nature Communications, 12, (1), 2021
Escartin, C. and Galea, E. and Lakatos, A. and Oâ Callaghan, J.P. and Petzold, G.C. and Serrano-Pozo, A. and SteinhÀuser, C. and Volterra, A. and Carmignoto, G. and Agarwal, A. and Allen, N.J. and Araque, A. and Barbeito, L. and Barzilai, A. and Bergles, D.E. and Bonvento, G. and Butt, A.M. and Chen, W.-T. and Cohen-Salmon, M. and Cunningham, C. and Deneen, B. and De Strooper, B. and DÃaz-Castro, B. and Farina, C. and Freeman, M. and Gallo, V. and Goldman, J.E. and Goldman, S.A. and Götz, M. and Gutiérrez, A. and Haydon, P.G. and Heiland, D.H. and Hol, E.M. and Holt, M.G. and Iino, M. and Kastanenka, K.V. and Kettenmann, H. and Khakh, B.S. and Koizumi, S. and Lee, C.J. and Liddelow, S.A. and MacVicar, B.A. and Magistretti, P. and Messing, A. and Mishra, A. and Molofsky, A.V. and Murai, K.K. and Norris, C.M. and Okada, S. and Oliet, S.H.R. and Oliveira, J.F. and Panatier, A. and Parpura, V. and Pekna, M. and Pekny, M. and Pellerin, L. and Perea, G. and Pérez-Nievas, B.G. and Pfrieger, F.W. and Poskanzer, K.E. and Quintana, F.J. and Ransohoff, R.M. and Riquelme-Perez, M. and Robel, S. and Rose, C.R. and Rothstein, J.D. and Rouach, N. and Rowitch, D.H. and Semyanov, A. and Sirko, S. and Sontheimer, H. and Swanson, R.A. and Vitorica, J. and Wanner, I.-B. and Wood, L.B. and Wu, J. and Zheng, B. and Zimmer, E.R. and Zorec, R. and Sofroniew, M.V. and Verkhratsky, A., Reactive astrocyte nomenclature, definitions, and future directions, Nature Neuroscience, 24, (3), 2021, p312-325
O'Neill, E. and Griffin, Ã .W. and O'Sullivan, R. and Murray, C. and Ryan, L. and Yssel, J. and Harkin, A. and Cunningham, C., Acute neuroinflammation, sickness behavior and working memory responses to acute systemic LPS challenge following noradrenergic lesion in mice, Brain, Behavior, and Immunity, 94, 2021, p357-368
McGarry, N. and Murray, C.L. and Garvey, S. and Wilkinson, A. and Tortorelli, L. and Ryan, L. and Hayden, L. and Healy, D. and Griffin, E.W. and Hennessy, E. and Arumugam, M. and Skelly, D.T. and Mitchell, K.J. and Cunningham, C., Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age, Brain, Behavior, and Immunity, 95, 2021, p413-428
Lopez-Rodriguez, A.B. and Hennessy, E. and Murray, C.L. and Nazmi, A. and Delaney, H.J. and Healy, D. and Fagan, S.G. and Rooney, M. and Stewart, E. and Lewis, A. and de Barra, N. and Scarry, P. and Riggs-Miller, L. and Boche, D. and Cunningham, M.O. and Cunningham, C., Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction, Alzheimer's and Dementia, 17, (10), 2021, p1735-1755
Malebari A.M., Wang S., Greene T.F., O'Boyle N.M., Fayne D., Khan M.F., Nathwani S.M., Twamley B., McCabe T., Zisterer D.M., Meegan M.J., Synthesis and antiproliferative evaluation of 3-chloroazetidin-2-ones with antimitotic activity: Heterocyclic bridged analogues of combretastatin A-4, Pharmaceuticals, 14, (11), 2021, part. 1119-
Hanlon MM, Canavan M, Barker BE, Fearon U., Metabolites as drivers and targets in Rheumatoid Arthritis., Clinical and experimental immunology, 2021
Doran, C.G., Sugisawa, R., Carty, M., Roche, F., Fergus, C., Hokamp, K., Kelly, V.P. and Bowie, A.G., Next generation SARM1 knockout and epitope tagged CRISPR-Cas9-generated isogenic mice reveal that SARM1 does not participate in regulating nuclear transcription, despite confirmation of protein expression in macrophages, bioRxiv, 2021
Feng Gu, Aileen Krüger, Hannes G Roggenkamp, Rick Alpers, Dmitri Lodygin, Vincent Jaquet, Franziska Möckl, Lola C Hernandez C, Kai Winterberg, Andreas Bauche, Anette Rosche, Helmut Grasberger, John Y Kao, Daniel Schetelig, René Werner, Katrin Schröder, Michael Carty, Andrew G Bowie, Samuel Huber, Chris Meier, Hans-Willi Mittrücker, Joerg Heeren, Karl-Heinz Krause, Alexander Flügel, Björn-Philipp Diercks, Andreas H Guse, Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation, Science Signaling, 14, (709), 2021
Ciara G Doran, Ryoichi Sugisawa, Michael Carty, Fiona Roche, Claire Fergus, Karsten Hokamp, Vincent P Kelly, Andrew G Bowie, CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages, Journal of Biological Chemistry, 297, (6), 2021
Turley JL, Lavelle EC., Fatballs foster fabulous follicles., Immunity, 54, (12), 2021, p2695-2697
Muñoz-Wolf N, Lavelle EC., Promotion of trained innate immunity by nanoparticles., Seminars in immunology, 2021, p101542
Nidhi Kedia-Mehta, Laura Tobin, Vanessa Zaiatz-Bittencourt, Marta M Pisarska, Conor De Barra, Chloe Choi, Einas Elamin, Donal O'Shea , Clair M Gardiner, David K Finlay, Andrew E Hogan , Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity, Blood Advances, 5, (21), 2021, p4447-4455
David Finlay, Nutrients and Metabolites controlling lymphocyte responses, Portuguese Society of Immunology annual meeting, Online, 21st May, 2021, Portuguese Society of Immunology
David Finlay, Nutrients and Metabolites controlling Natural Killer cell responses, Agilent Technologies Webinar Series, Online, 18th Nov, 2021, Agilent Technologies
David Finlay, Nutrients and Metabolites controlling Natural Killer cell responses, Leeds Institute of Medical Research Virtual seminar series, Online, 21st Oct, 2021, Dr Robert Salmond
David Finlay, Science, Nutrients and Immunity. What is the stress about?, ISI Early Career Researchers Meeting, Dublin, 25th Nov, 2021, Irish Society of Immunology
David Finlay, Natural Killer cell and cancer cell metabolism intertwined, EMBO Workshop on Cancer Immunometabolism, Sitges, Spain, 29th Nov - 1st Dec, 2021, EMBO
Magnano S, Hannon Barroeta P, Duffy R, O'Sullivan J, Zisterer DM., Cisplatin induces autophagy-associated apoptosis in human oral squamous cell carcinoma (OSCC) mediated in part through reactive oxygen species., Toxicology and applied pharmacology, 427, 2021, p115646
Choi C, Finlay DK, Optimising NK cell metabolism to increase the efficacy of cancer immunotherapy, Stem Cell Res Ther, 12, (1), 2021
Timmons GA, Carroll RG, O'Siorain JR, Cervantes-Silva MP, Fagan LE, Cox SL, Palsson-McDermott E, Finlay DK, Vincent EE, Jones N, Curtis AM, The Circadian Clock Protein BMAL1 Acts as a Metabolic Sensor In Macrophages to Control the Production of Pro IL-1β, Frontiers in Immunology, (12), 2021
Woods E, Zaiatz-Bittencourt V, Bannan C, Bergin C, Finlay DK, Hoffmann M, Brown A, Turner B, Makvandi-Nejad S, Vassilev V, Capone S, Folgori A, Hanke T, Barnes E, Dorrell L, Gardiner CM, Specific human cytomegalovirus signature detected in NK cell metabolic changes post vaccination, NPJ Vaccines, 6, (1), 2021, p112-
Vincent P. Kelly, RNA at the therapeutic frontier: Autoimmunity, cancer & neurodegeneration, UCC Biochemical Society, University College Cork, 1st Dec, 2021, Dr. Gary Loughran
Fox PG, Schiavetti F, Rappuoli R, McLoughlin RM, Bagnoli F, Staphylococcal Protein A Induces Leukocyte Necrosis by Complexing with Human Immunoglobulins., mBio, 2021
Vozza EG, Mulcahy ME, McLoughlin RM, Making the Most of the Host; Targeting the Autophagy Pathway Facilitates Staphylococcus aureus Intracellular Survival in Neutrophils., Frontiers in immunology, 2021
O'Brien MB, McLoughlin RM, Roche C, Nelson CD, Meade KG, Effect of IL-8 haplotype on temporal profile in circulating concentrations of interleukin 8 and 25(OH) vitamin D in Holstein-Friesian calves., Veterinary immunology and immunopathology, 2021
Douglas E, Brignoli T, Recker M, O"Brien E, McLoughlin RM, Massey RC, Self-sensitisation of Staphylococcus aureus to the antimicrobial factors found in human blood, 2021
Clegg J, Soldaini E, McLoughlin RM, Rittenhouse S, Bagnoli F, Phogat S, Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies., Frontiers in immunology, 2021
Megan B. O"Brien, Charlotte L. Beynon, Rachel M. McLoughlin, Kieran G. Meade, The immune response in bovine primary dermal fibroblasts is influenced by Interleukin 8 promoter haplotype and vitamin D, Veterinary Immunology and Immunopathology, 238, 2021, p110291
Vincent P. Kelly, Genome engineering - Better humans.....and a better world?, UCC Technology Conference, University College Cork, 27th Nov, 2021, UCC MRT Society
Ofir-Birin Y, Ben Ami Pilo H, Cruz Camacho A, Rudik A, Rivkin A, Revach OY, Nir N, Block Tamin T, Abou Karam P, Kiper E, Peleg Y, Nevo R, Solomon A, Havkin-Solomon T, Rojas A, Rotkopf R, Porat Z, Avni D, Schwartz E, Zillinger T, Hartmann G, Di Pizio A, Quashie NB, Dikstein R, Gerlic M, Torrecilhas AC, Levy C, Nolte-'t Hoen ENM, Bowie AG, Regev-Rudzki N., Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration., Nature communications, 12, (1), 2021, p4851
Floudas A, Neto N, Orr C, Canavan M, Gallagher P, Hurson C, Monaghan MG, Nagpar S, Mullan RH, Veale DJ, Fearon U., Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis., Annals of the rheumatic diseases, 2021
Floudas A, Canavan M, McGarry T, Mullan R, Nagpal S, Veale DJ, Fearon U., ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis, Cells, ;10(3):, (64), 2021, pdoi: 10.33-
Saoirse Elizabeth O'Sullivan, Andrew S Yates, Richard Porter, The peripheral cannabinoid receptor type 1 (CB1) as a molecular target for modulating body weight in man, Molecules, 26, (20), 2021, p6178-
McDonald AG, Davey GP, O-Glycologue: A Formal-Language-Based Generator of O-Glycosylation Networks, Methods Mol Biol., 2370, 2021, p223 - 236
Hayes JM, O'Hara DM, Davey GP, Metabolic Labeling of Primary Neurons Using Carbohydrate Click Chemistry, Methods Mol Biol, 2021, p315 - 322
O'Farrell LK, Fraser AD, Davey GP, Monitoring the Sialome on Human Immune Cells , Methods Mol Biol, 2370, 2021, p323 - 329
Smith J, Millán-Martín S, Mittermayr S, Hilborne V, Davey G, Polom K, Roviello F, Bones J., 2-Dimensional ultra-high performance liquid chromatography and DMT-MM derivatization paired with tandem mass spectrometry for comprehensive serum N-glycome characterization, Analytica Chimica Acta, 1179, (338840), 2021
Lavelle, E.C. and Ward, R.W., Mucosal vaccines â" fortifying the frontiers, Nature Reviews Immunology, 2021
Lavelle, E.C. and Ward, R.W., Publisher Correction: Mucosal vaccines â" fortifying the frontiers (Nature Reviews Immunology, (2021), 10.1038/s41577-021-00583-2), Nature Reviews Immunology, 2021
Scott, L.M. and Vincent, E.E. and Hudson, N. and Neal, C. and Jones, N. and Lavelle, E.C. and Campbell, M. and Halestrap, A.P. and Dick, A.D. and Theodoropoulou, S., Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors, JCI Insight, 6, (8), 2021
Albutti, A. and Longet, S. and McEntee, C.P. and Quinn, S. and Liddicoat, A. and Rîmniceanu, C. and Lycke, N. and Lynch, L. and Cardell, S. and Lavelle, E.C., Type ii nkt cell agonist, sulfatide, is an effective adjuvant for oral heat-killed cholera vaccines, Vaccines, 9, (6), 2021
Turley, J.L. and Moran, H.B.T. and McEntee, C.P. and O'Grady, K. and Muñoz-Wolf, N. and Jin, L. and Follmann, F. and Andersen, P. and Andersson, M. and Lavelle, E.C., Chitin-derived polymer deacetylation regulates mitochondrial reactive oxygen species dependent cGAS-STING and NLRP3 inflammasome activation, Biomaterials, 275, (120961), 2021
Murphy, D.M. and Mills, K.H.G. and Basdeo, S.A., The Effects of Trained Innate Immunity on T Cell Responses; Clinical Implications and Knowledge Gaps for Future Research, Frontiers in Immunology, 12, (706583), 2021
Borkner, L. and Curham, L.M. and Wilk, M.M. and Moran, B. and Mills, K.H.G., Correction: IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils (Mucosal Immunology, (2021), 14, 5, (1183-1202), 10.1038/s41385-021-00407-5), Mucosal Immunology, 14, (5), 2021, p1218-1219
Vincent P. Kelly, Queuine-mimetics - hitting the reset button in autoimmunity, European Epitranscriptomics Network, Online (Trento Italy), 21st Sept, 2021, Prof. Alessandro Quattrone
James J. Phelan and Frederick J. Sheedy., Phagocyte metabolism: neutrophils have their cake but don't eat it., Trends in Immunology, 2021
Elisabeth Littwitz-Salomon Diana Moreira Joe N. Frost Chloe Choi Kevin T. Liou David K. Ahern Simon O'Shaughnessy Bernd Wagner Christine A. Biron Hal Drakesmith Ulf Dittmer David K Finlay , Metabolic requirements of NK cells during the acute response against retroviral infection, Nature Communications, 12, (1), 2021, p5373-
Ghanim M, Relitti N, McManus G, Butini S, Cappelli A, Campiani G, Mok KH, Kelly VP, A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds., Scientific reports, 2021
Agnew, A., Nulty, C., Creagh, E.M., Regulation, Activation and Function of Caspase-11 during Health and Disease., International Journal of Molecular Science, 22, (4), 2021, p1506-
McKenna E, Mhaonaigh AU, Wubben R, Dwivedi A, Hurley T, Kelly LA, Stevenson NJ, Little MA, Molloy EJ, Neutrophils: Need for Standardized Nomenclature., Frontiers in immunology, 2021
McDonald AG and Davey GP , Simulating the enzymes of ganglioside biosynthesis with Glycologue, Beilstein Journal of Organic Chemistry , 2021
Cunningham KT, Mills KHG., Trained Innate Immunity in Hematopoietic Stem Cell and Solid Organ Transplantation., Transplantation, 2021
Lynne A. Kelly, Mary I. O"Dea, Zunera Zareen, Ashanty M. Melo, Ellen McKenna, Tammy Strickland, Victoria Mc Eneaney, Veronica Donoghue, Geraldine Boylan, Deirdre Sweetman, John Butler, Claudine Vavasseur, Jan Miletin, Afif F.El"Khuffash, Luke A.J. O"Neill, John J. O"Leary, Eleanor J. Molloy, Altered Inflammasome activation in Neonatal Encephalopathy persists in Childhood, Clinical & Experimental Immunology, 2021
Borkner L, Curham LM, Wilk MM, Moran B, Mills KHG., IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils., Mucosal immunology, 2021
Carty M, Guy C, Bowie AG., Detection of Viral Infections by Innate Immunity., Biochemical pharmacology, 183, 2021, p114316
Cunningham Kyle , Finlay Conor , Mills Kingston H, Helminth Imprinting of Hematopoietic Stem Cells Sustains Anti-Inflammatory Trained Innate Immunity That Attenuates Autoimmune Disease, Journal of Immunology, 206, (7), 2021, p1618 - 1630
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