Publications
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42 publications from 2019
Galván-Peña, S., Carroll, R.G., Newman, C., (...), Modis, L.K., O'Neill, L.A., Malonylation of GAPDH is an inflammatory signal in macrophages, Nature Communications, 10, (1), 2019, p338-
Qasim Warraich M, Ghion A, Perdisatt L, Oâ Neill L, Casey A, Oâ Connor C, In vitro cytotoxicity, cellular uptake, reactive oxygen species and cell cycle arrest studies of novel ruthenium(II) polypyridyl complexes towards A549 lung cancer cell line, Drug and Chemical Toxicology, 2019
Gul S.-E, Oâ neill L, Cassidy J, Naydenova I, Modified surface relief layer created by holographic lithography: Application to selective sodium and potassium sensing, Sensors (Switzerland), 19, (5), 2019
Oâ Neill L.A.J, Artyomov M.N, Itaconate: the poster child of metabolic reprogramming in macrophage function, Nature Reviews Immunology, 19, (5), 2019, p273 - 281
Finlay, D.K., N-myristoylation of AMPK controls T cell inflammatory function, Nature Immunology, 20, (3), 2019, p252-254
Saraswati AP, Relitti N, Brindisi M, Gemma S, Zisterer D, Butini S & Campiani G, Raising the bar in anticancer therapy:recent advances in, and perspectives on, telomerase inhibitors, Drug Discovery Today, 2019
Jones N, Vincent EE, Cronin JG, Panetti S, Chambers M, Holm SR, Owens SE, Francis NJ, Finlay DK, Thornton CA, Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation, Nature Communications, 10, (1), 2019, p2042-
O'Brien A, Loftus RM, Pisarska MM, Tobin LM, Bergin R, Wood NAW, Foley C, Mat A, Tinley FC, Bannan C, Sommerville G, Veerapen N, Besra GS, Sinclair LV, Moynagh PN, Lynch L, Finlay DK, O'Shea D Hogan AE, Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses, Journal of Immunology, 202, (12), 2019, p3404 - 3411
Neher J.J, Cunningham C, Priming Microglia for Innate Immune Memory in the Brain, Trends in Immunology, 40, (4), 2019, p358 - 374
Skelly D.T, Griffin à .W, Murray C.L, Harney S, Oâ Boyle C, Hennessy E, Dansereau M.-A, Nazmi A, Tortorelli L, Rawlins J.N, Bannerman D.M, Cunningham C, Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms (Molecular Psychiatry, (2018), 10.1038/s41380-018-0075-8), Molecular Psychiatry, 2019
Connolly R, Denton M.D, Humphreys H, McLoughlin R.M, Would hemodialysis patients benefit from a Staphylococcus aureus vaccine?, Kidney International, 95, (3), 2019, p518 - 525
O'Brien E.C, McLoughlin R.M, Considering the â~Alternativesâ for Next-Generation Anti-Staphylococcus aureus Vaccine Development, Trends in Molecular Medicine, 25, (3), 2019, p171 - 184
Lacey K.A, Mulcahy M.E, Towell A.M, Geoghegan J.A, McLoughlin R.M, Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target, PLoS pathogens, 15, (4), 2019, pe1007713-
Harmon C, Robinson M.W, Hand F, Almuaili D, Mentor K, Houlihan D.D, Hoti E, Lynch L, Geoghegan J, O'Farrelly C, Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis, Cancer immunology research, 7, (2), 2019, p335 - 346
Kohlgruber A.C, Gal-Oz S.T, LaMarche N.M, Shimazaki M, Duquette D, Koay H.-F, Nguyen H.N, Mina A.I, Paras T, Tavakkoli A, von Andrian U, Uldrich A.P, Godfrey D.I, Banks A.S, Shay T, Brenner M.B, Lynch L, Erratum to: γΎ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis (Nature Immunology, (2018), 19, 5, (464-474), 10.1038/s41590-018-0094-2), Nature Immunology, 20, (3), 2019, p373-
Schwartz C, Moran T, Saunders S.P, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, Oâ Neill L, Irvine A.D, McKenzie A.N.J, Ogg G, Walsh P.T, Demengeot J, Fallon P.G, Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β, Allergy: European Journal of Allergy and Clinical Immunology, 2019, p1--
Wilk M.M, Borkner L, Misiak A, Curham L, Allen A.C, Mills K.H.G, Immunization with whole cell but not acellular pertussis vaccines primes CD4 T
Quinn S.M, Raverdeau M, McGinley A.M, Mills K.H.G, Helminths products directly modulate TÂ cells that mediate experimental autoimmune encephalomyelitis, European Journal of Immunology, 2019
Raverdeau M, Christofi M, Malara A, Wilk M.M, Misiak A, Kuffova L, Yu T, McGinley A.M, Quinn S.M, Massilamany C, Reddy J, Forrester J.V, Mills K.H.G, Retinoic acid-induced autoantigen-specific type 1 regulatory T cells suppress autoimmunity, EMBO Reports, 20, (5), 2019
Clowry, J., Irvine, A.D., McLoughlin, R.M., Next-generation anti"Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?, Journal of Allergy and Clinical Immunology, 143, (1), 2019, p78-81
Müller M, Legrand C, Tuorto F, Kelly VP, Atlasi Y, Lyko F, Ehrenhofer-Murray AE., Queuine links translational control in eukaryotes to a micronutrient from bacteria., Nucleic acids research, 2019
Vincent P. Kelly, The queuine micronutrient pathway as a therapeutic target in autoimmune disease, Translational Medicine Research Program, The Hospital for Sick Children, Toronto Canada, 14th Jan 2019, 2019, Dr. Colin McKerlie
Carty M, Bowie AG., SARM: from immune regulator to cell executioner., Biochemical pharmacology, 2019
Mary F Rooney, Emmeline W Hill, Vincent Kelly and Richard K Porter, Genotype variation at the MSTN locus is associated with skeletal muscle Coenzyme Q level in untrained Thoroughbred horses., Cell Symposium: Exercise Metabolism, Sitges, Barcelona, Spain, May, 2019
Richard K. Porter, Oxygen Consumption as a measure of Cellular Energy Metabolism, Institute of Genomics and Integrative Biology, New Delhi, India, February, 2019
Richard K. Porter, Oxygen Consumption as a measure of Cellular Energy Metabolism, Indian Institute of Science, Bangalore, India, February, 2019
Emma O'Connor, Richard K. Porter, Patrick T. Walsh, The Role of Mitochondrial Uncoupling Protein 3 in T Cell Function, Frontiers in Immunology, 2019
Nazmi, A., Field, R.H., Griffin, E.W., Haugh, O., Hennessy, E., Cox, D., Reis, R., Tortorelli, L., Murray, C.L., Lopez-Rodriguez, A.B., Lavelle, E.C., Dunne, A. and Cunningham,C. , Chronic neurodegeneration induces Type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression, Glia, 67, 2019, p1254 - 1276
O'Grady, K., Hearnden, C.C.H., Bento, D., Oleszycka, E., Andersen, P., Muñoz-Wolf, N. and Lavelle, E.C. , IL-33 is a negative regulator of vaccine-induced antigen-specific cellular immunity, The Journal of Immunology, 2019
Chang Y.-H., Nishimura S., Oishi H., Kelly V.P., Kuno A., Takahashi S., TRMT2A is a novel cell cycle regulator that suppresses cell proliferation, Biochemical and Biophysical Research Communications, 508, (2), 2019, p410 - 415, p410-415
David Finlay, Metabolic Regulation of NK cell responses, Immunometabolism: Fundamentals to Prospective New Therapies , Boston, 25th June, 2019, Abcam, Prof Luke O'Neill
David Finlay, NK cell metabolism; Implications for anti-tumour responses, Seminar, Imperial College London, 13th May, 2019, Prof Adam Byrne
David Finlay, Metabolic regulation of NK cell responses, Fuelling the immune response: UK immunometabolism meeting 2019, Newcastle, 14th March, 2019, British Society for Immunology's Immunometabolism Affinity Group
Brian Flood*, Joan Manils*, Ciara Nulty, Ewelina Flis, Sinead Kenealy, Gillian Barber, Joanna Fay, Kingston H. G. Mills, Elaine W. Kay and Emma M. Creagh. , Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis, Oncogene, 38, (14), 2019, p2658-2674
David Finlay, Metabolic regulation of Natural Killer cell anti-tumour responses, Seminar, Newcastle University, 13th March, 2019, Dr Kevin Marchbank
David Finlay, Metabolic regulation of NK cell responses, IACR annual conference, Belfast, 21st Feburary, 2019
David Finlay, Metabolic regulation of NK cell responses, Seminar, University of Dundee, 8th Feburary, 2019, Prof Doreen Cantrell
Katie O'Brien and David. K Finlay, Immunometabolism and Natural Killer cell responses, Nature Reviews Immunology, 19, (5), 2019, p282 - 290
Nidhi Kedia-Mehta and David. K Finlay, Competition for nutrients; an emerging role in controlling immune responses, Nature Communications, 10, (1), 2019, p2123-
Cunniffe GM, Díaz-Payno PJ, Sheehy EJ, Critchley SE, Almeida HV, Pitacco P, Carroll SF, Mahon OR, Dunne A, Levingstone TJ, Moran CJ, Brady RT, O'Brien FJ, Brama PAJ, Kelly DJ, Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues, Biomaterials. , 188, 2019, p63-73
Sadhbh O'Neill, Richard K. Porter, Vanesa G. Martinez, Lorraine, O'Driscoll , 2-Deoxy-D-Glucose preferentially inhibits aggressive triple-negative breast cancer cells by targeting glycolysis and the cancer stem cell phenotype , Scientific Reports, 9, (1), 2019, p3788 - 3798
McKenna C, Porter RK, Waters SM, Cormican P, McGee M, Kelly AK and Kenny D, An examination of the transcriptional control of energetic efficiency in skeletal muscle and hepatic tissue from beef cattle divergent for residual feed intake, 2019