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Professor Cliona O'Farrelly

Comparative Immunology

Photo of C. O'Farrelly

Professor Cliona O’Farrelly
Phone: +353-1-8963175
Fax: +353-1-6772400
Location: Room 4.12, Trinity Biomedical Sciences Institute

A certificate for highly cited research in the journal Veterinary Immunology and Immunopathology was awarded in November 2016 to Prof. O'Farrelly by the editors of the journal in recognition of the contribution to the quality of the journal made by her paper “Endometrial epithelial cells are potent producers of tracheal antimicrobial peptide and serum amyloid A3 gene expression in response to E. coli stimulation”.

SFI Resistance Study

For information on the SFI-funded HCV Resistance Study, involving Irish women exposed to contaminated Anti-D, please see our Hepatitis C page.


View audio/video clip of Prof O'Farrelly talking about her research (mp4, 54.4MB)

The gut, liver and uterus are sites of intense immunological activity even when healthy.  In these organs, harmless foreign antigens of commensal and foetal origin require tolerance while at the same time, effective tumour and pathogen surveillance must be maintained. The Comparative Immunology Group (CIG) studies immune responses within these different organs in both humans and mammals. Our studies investigate genes, molecules and mechanisms of the innate immune system with the aim of gaining novel insights into immune processes.

Liver Immunology:

Reproductive Immunology:

Cancer Immunology:

Comparative Immunology:


Information on teaching and outreach activities and achievements.
More details


Post-Doctoral Researchers: Dr Mark Robinson and Dr Lena Fischer
Research Associates: Margaret Needham
Clinical Researchers: Dr Fiona Hand
Graduate Students: Cathal Harmon, Paul Kelly, Amy Brewer (Teagasc), Dalal Almuaili, Jamie Sugrue and Sarah Swoboda
Lab personnel details


Dr Kieran Meade, Teagasc
Professor Suzanne Norris, St. James’s Hospital
Members of the Irish Hepatitis C Outcomes Research Network (ICORN)
Dr Andrew Lloyd, Carlow Institute of Technology
Professor Hidde Ploegh, MIT
Dr Lydia Lynch, Harvard/School of Biochemistry and Immunology, Trinity College Dublin


Our group is currently funded by Science Foundation Ireland, the Health Research Board, the Irish Department of Agriculture and Food, and Teagasc, the Irish Agriculture and Food Development Authority.

C O'Farrelly funders


Informal enquiries from talented and enthusiastic researchers are welcome and we are interested in supporting PhD and Fellowship applications. If you are keen to pursue PhD or postdoctoral research in our group, please email, describing your particular interests and how they align with our research.



Last updated 24 July 2018 (Email).