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INCHSA Labs and Equipment


Screening Lab Layout


Data Analysis Lab

INCHSA Equipment Portfolio

Equipment Portfolio Imaging


Equipment Portfolio Portfolio

The Cellomics KineticScan features

  • High Resolution Cellular and Sub-cellular Imaging with sub-cellular resolution.
  • Kinetic Assay Scheduling Software Permits fully automated, unattended execution of complex experimental protocols.
  • Integrated Liquid Handling for reagent delivery, mixing and cell washing during live cell experiments.
  • Onboard Environmental Control Enables live cell experiments physiological conditions throughout the assay time course.
  • Flexible Optical System allow use with a wide variety of fluorescent reporters, including FRET and ratio metric imaging.
  • Because of this units advanced functionality and on board environmental control and liquid handling, we currently reserve this system as a dedicated assay development and live cell assay system.

Equipment Portfolio Imaging

The GE INcell 1000 Fixed Endpoint Screening Machine with Robotic Plate Handling Robot Features .

  • High Resolution Cellular and Sub-cellular Imaging with sub-cellular resolution.
  • Kinetic Assay Scheduling Software Permits fully automated, unattended execution of complex experimental protocols.
  • Integrated Liquid Handling for reagent delivery, mixing and cell washing during live cell experiments.
  • Onboard Environmental Control Enables live cell experiments physiological conditions throughout the assay time course.
  • Flexible Optical System allow use with a wide variety of fluorescent reporters, including FRET and ratio metric imaging.
  • Because of this units advanced functionality and on board environmental control and liquid handling, we currently reserve this system as a dedicated assay development and live cell assay system.
  • Plate handler fully automated and integrated with Overlord II software.
  • A full range of application specific image analysis algorithms covering a vast range of biology's

Equipment Portfolio Imaging

The GE INcell 1000 Kinetic Assay Development Machine showing screen shot from Incell Investigator image analysis software

  • High Resolution Cellular and Sub-cellular Imaging with sub-cellular resolution.
  • Kinetic Assay Scheduling Software Permits fully automated, unattended execution of complex experimental protocols.
  • Integrated Liquid Handling for reagent delivery, mixing and cell washing during live cell experiments.
  • Onboard Environmental Control Enables live cell experiments physiological conditions throughout the assay time course.
  • Flexible Optical System allow use with a wide variety of fluorescent reporters, including FRET and ratio metric imaging.
  • Because of this units advanced functionality and on board environmental control and liquid handling, we currently reserve this system as a dedicated assay development and live cell assay system.
  • A full range of application specific image analysis algorithms covering a vast range of biology's 
  • Optigrid Confocality
  • Full Environmental control permitting long term live cell assays
  • Onboard automated Liquid handling for treating cells in situ. 

Equipment Portfolio

Plate Handling Robot


Plate Handling Equipment

Selective Compliant Articulated Robot Arm (SCARA)

Features

  • Fully automated and integrated using Overlord II automation and scheduling software
  • Stack Capacity 90 SBS standard micro-plates.
  • Designed for fully unsupervised operation

Plate Handling Sealer

Plate Handling Sealer

Porvair Mini Seal

Features

  • Will Seal a wide range of plates
  • Pre-programmable temperature and
  • Safety features e.g. Double hand actuation
  • Small foot print
  • Adhesive seals have not performed well for us

Liquid Handling

Liquid Handling Figure 1

The Matrix Hydra                                                       Screen shot of graphical user interface

  • Fully automated liquid handling system, has a 96 well head which can dispense liquids directly into 96 or 384 well plates.
  • Can aspirate and dispense volumes ranging from 1 - 580 micro litres.
  • Fully automated moving stage with 3 plate positions and a dedicated active wash bath.
  • Active wash bath can clean 96 tip head during liquid handling tasks, preventing risk of cross contamination between experiments.
  • Functions include; Bulk aspirating, dispensing, Plate replication, plate washing, Plate reformatting (96 to 384 and vice versa).
  • Intuitive graphical user interface

Liquid Handling Equipment Figure 2

The Deerac Equator                                                     Screen Shot of Graphic User Interface

Deerac Equator

  • 8 channel liquid dispenensing system.
  • Dynamic range of dispensing volumes 50nl-1ml per channel, nano spotting.
  • Cell dispensing and gradient functions.
  • Can be used with 96,384,1536 well plates, 4 plate positions, fully automated.

Liquid Handling

Liquid Handling Equipment

Matrix Wellmate.

  • Designed for bulk dispensing of reagents and cells.
  • Compatible for both 96 and 384 SBS format plates.
  • Dispensing range 1 -200 ul
  • 8 channel system featuring disposable dispensing head

Liquid Handling Figure 4

Apricot personal 550 liquid handling system

  • Utilises either fixed or disposable tips
  • Semi automated
  • Compatible with 96 and 384 SBS compatible micro plates
  • Will perform serial dispensing for rapid plate filling or dosing.

High Throughput Electro-poration

High Throughput Electro-poration

BTX High Throughput Square wave electro-porator

  • Capable of transfecting 96 samples  simultaneously
  • Proven utility with siRNA and plasmids
  • Excellent means of transfecting primary cells
  • Fully programmable and automated

The Perkin Elmer Victor II

The Perkin Elmer Victor II

  • Plate reader and liquid handler
  • Capable of reading 96 and 384 microplates.
  • Suitable for absorbance, Fluorescence and luminescence assays.
  • Fully automated

The Cedex XS is a semi-automated image-based cell analyzer

Cedex XS

Measurement results of Cedex XS: cell viability
cell diameter
cell size
cell morphology
aggregation rate
specific growth rate and doubling time

The CellaVista Automated imaging platform

The CellaVista Automated imaging platform

Culture system Range SBS format 6, 12, 24, 48, 96 and 384 well microplates, culture dishes, microscope slides, T-flasks Nunclon 75; for non-SBS formats, an additional adapter may be required.
Illumination Brightfield + up to 6 fluorescence options
Objective Lenses 4x + 2x, 10x, 20x, 40x