John Reynolds
Professor & Head of Department, Surgery

Publications and Further Research Outputs

Peer-Reviewed Publications

Donohoe C.L, Lysaght J, O'Sullivan J, Reynolds J.V, Emerging Concepts Linking Obesity with the Hallmarks of Cancer, Trends in Endocrinology and Metabolism, 28, (1), 2017, p46 - 62 Journal Article, 2017 URL DOI

Guinan, E.M., Dowds, J., Donohoe, C., Reynolds, J.V., Hussey, J., The physiotherapist and the esophageal cancer patient: From prehabilitation to rehabilitation, Diseases of the Esophagus, 30, (1), 2017, p1-12 Journal Article, 2017 DOI

O†Brien H, Mohan H, Hare C.O, Reynolds J.V, Kenny R.A, Mind Over Matter? The Hidden Epidemic of Cognitive Dysfunction in the Older Surgical Patient, Annals of Surgery, 265, (4), 2017, p677-691 Journal Article, 2017 URL DOI

Ahmed Z, Elliott J.A, King S, Donohoe C.L, Ravi N, Reynolds J.V, Risk Factors for Anastomotic Stricture Post-esophagectomy with a Standardized Sutured Anastomosis, World Journal of Surgery, 41, (2), 2017, p487 - 497 Journal Article, 2017 URL DOI

Widdowson W.M, McGowan A, Phelan J, Boran G, Reynolds J, Gibney J, Vascular disease is associated with the expression of genes for intestinal cholesterol transport and metabolism, Journal of Clinical Endocrinology and Metabolism, 102, (1), 2017, p326 - 335 Journal Article, 2017 DOI URL

Conroy M.J, Galvin K.C, Doyle S.L, Kavanagh M.E, Mongan A.-M, Cannon A, Moore G.Y, Reynolds J.V, Lysaght J, Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients, Inflammation, 39, (5), 2016, p1729 - 1736 Journal Article, 2016 DOI URL

Conroy M.J, Galvin K.C, Kavanagh M.E, Mongan A.M, Doyle S.L, Gilmartin N, O'Farrelly C, Reynolds J.V, Lysaght J, CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer, Immunology and Cell Biology, 94, (6), 2016, p531 - 537 Journal Article, 2016 URL DOI

Messager M, de Steur W, Boelens P.G, Jensen L.S, Mariette C, Reynolds J.V, Osorio J, Pera M, Johansson J, KoÅ'odziejczyk P, Roviello F, De Manzoni G, Mönig S.P, Allum W.H, Description and analysis of clinical pathways for oesophago-gastric adenocarcinoma, in 10 European countries (the EURECCA upper gastro intestinal group â€" European Registration of Cancer Care), European Journal of Surgical Oncology, 42, (9), 2016, p1432 - 1447 Journal Article, 2016 URL DOI

Conroy M.J, Fitzgerald V, Doyle S.L, Channon S, Useckaite Z, Gilmartin N, O†Farrelly C, Ravi N, Reynolds J.V, Lysaght J, The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function, Journal of Leukocyte Biology, 100, (6), 2016, p1435 - 1442 Journal Article, 2016 DOI URL

Heneghan H.M, Donohoe C, Elliot J, Ahmed Z, Malik V, Ravi N, Reynolds J.V, Can CT-PET and endoscopic assessment PostNeoadjuvant Chemoradiotherapy predict residual disease in esophageal cancer?, Annals of Surgery, 264, (5), 2016, p831 - 838 Journal Article, 2016 DOI URL

Guinan, E.M., Doyle, S.L., O"Neill, L., Dunne, M.R., Foley, E.K., O"Sullivan, J., Reynolds, J.V., Hussey, J., Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study, Supportive Care in Cancer, 25, (3), 2016, p749 - 756 Journal Article, 2016 DOI

Kavanagh ME, Conroy MJ, Clarke NE, Gilmartin NT, O'Sullivan KE, Feighery R, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Lysaght J, Impact of the inflammatory microenvironment on T-cell phenotype in the progression from reflux oesophagitis to Barrett oesophagus and oesophageal adenocarcinoma., Cancer letters, 370, (1), 2016, p117-24 Journal Article, 2016 DOI

Elliott, J.A., Docherty, N.G., Eckhardt, H.-G., Doyle, S.L., Guinan, E.M., Ravi, N., Reynolds, J.V., Roux, C.W.L., Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study, Annals of Surgery, 2016 Journal Article, 2016 TARA - Full Text DOI

Messager M, De Steur W.O, Van Sandick J.W, Reynolds J, Pera M, Mariette C, Hardwick R.H, Bastiaannet E, Boelens P.G, Van Develde C.J.H, Allum W.H, Variations among 5 European countries for curative treatment of resectable oesophageal and gastric cancer: A survey from the EURECCA Upper GI Group (EUropean REgistration of Cancer CAre), European Journal of Surgical Oncology, 42, (1), 2016, p116 - 122 Journal Article, 2016 URL DOI

Donohoe C.L, Reynolds J.V, Letter to the Co-Editors-in-Chief, Radiotherapy and Oncology, Radiotherapy and Oncology, 118, (1), 2016, p215- Journal Article, 2016 URL DOI

Phelan JJ, Feighery R, Eldin OS, Meachair SÓ, Cannon A, Byrne R, MacCarthy F, O'Toole D, Reynolds JV, O'Sullivan J, Examining the connectivity between different cellular processes in the Barrett tissue microenvironment., Cancer letters, 371, (2), 2016, p334-46 Journal Article, 2016 DOI

Mongan A.M, Lynam-Lennon N, Casey R, Maher S, Pidgeon G, Reynolds J.V, O†Sullivan J, Erratum to: Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma (Clin Transl Oncol, 10.1007/s12094-015-1411-y), Clinical and Translational Oncology, 18, (6), 2016, p651- Journal Article, 2016 DOI URL

Malik V, Johnston C, O'Toole D, Lucey J, O'Farrell N, Claxton Z, Reynolds J.V, Metabolic tumor volume provides complementary prognostic information to EUS staging in esophageal and junctional cancer, Dis Esophagus., 2016, p1= Journal Article, 2016 DOI URL

Walsh S.M, Casey S, Kennedy R, Ravi N, Reynolds J.V, Does the modified Glasgow Prognostic Score (mGPS) have a prognostic role in esophageal cancer?, Journal of Surgical Oncology, 113, (7), 2016, p732 - 737 Journal Article, 2016 URL DOI

Duggan S.P, Behan F.M, Kirca M, Zaheer A, McGarrigle S.A, Reynolds J.V, Vaz G.M.F, Senge M.O, Kelleher D, The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival, Scientific Reports, 6, 2016, p32638 - Journal Article, 2016 DOI TARA - Full Text URL

Abdel-Latif M.M, Inoue H, Kelleher D, Reynolds J.V, Factors regulating nuclear factor-kappa B activation in esophageal cancer cells: Role of bile acids and acid, Journal of Cancer Research and Therapeutics, 12, (1), 2016, p364 - 373 Journal Article, 2016 DOI URL

O'Farrell N.J, Feighery R, Picardo S.L, Lynam-Lennon N, Biniecka M, McGarrigle S.A, Phelan J.J, MacCarthy F, O'Toole D, Fox E.J, Ravi N, Reynolds J.V, O'Sullivan J, Changes in mitochondrial stability during the progression of the Barrett's esophagus disease sequence, BMC Cancer, 16, (1), 2016, p497- Journal Article, 2016 URL TARA - Full Text DOI

Elliott J.A, Reynolds J.V, le Roux C.W, Docherty N.G, Physiology, pathophysiology and therapeutic implications of enteroendocrine control of food intake, Expert Review of Endocrinology and Metabolism, 11, (6), 2016, p475 - 499 Journal Article, 2016 DOI URL

Lynam-Lennon N., Bibby B., Mongan A., Marignol L., Paxton C., Geiersbach K., Geiersbach K., Bronner M., Bronner M., O"Sullivan J., Reynolds J., Maher S., Maher S., Low MiR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma, Molecular Medicine, 22, 2016, p388-397 Journal Article, 2016 DOI

Malik V, Harmon M, Johnston C, Fagan A.J, Claxton Z, Ravi N, O''Toole D, Muldoon C, Keogan M, Reynolds J.V, Meaney J.F.M, Whole Body MRI in the Staging of Esophageal Cancer-A Prospective Comparison with Whole Body <sup>18</sup>F-FDG PET-CT, Digestive Surgery, 32, (5), 2015, p397 - 408 Journal Article, 2015 URL DOI

Elliott J.A, Donohoe C.L, Reynolds J.V, Obesity and increased risk of esophageal adenocarcinoma, Expert Review of Endocrinology and Metabolism, 10, (5), 2015, p511 - 523 Journal Article, 2015 DOI URL

Low DE, Alderson D, Cecconello I, Chang AC, Darling GE, D"Journo XB, Griffin SM, Hölscher AH, Hofstetter WL, Jobe BA, Kitagawa Y, Kucharczuk JC, Law SY, Lerut TE, Maynard N, Pera M, Peters JH, Pramesh CS, Reynolds JV, Smithers BM, van Lanschot JJ, International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG)., Annals of surgery, 262, (2), 2015, p286-94 Journal Article, 2015 DOI

Heneghan H.M, Zaborowski A, Fanning M, Mchugh A, Doyle S, Moore J, Ravi N, Reynolds J.V, Prospective study of malabsorption and malnutrition after esophageal and gastric cancer surgery, Annals of Surgery, 262, (5), 2015, p803 - 808 Journal Article, 2015 URL DOI

Bibby B.A.S, Reynolds J.V, Maher S.G, MicroRNA-330-5p as a putative modulator of neoadjuvant chemoradiotherapy sensitivity in oesophageal adenocarcinoma, PLoS ONE, 10, (7), 2015, p013418- Journal Article, 2015 URL TARA - Full Text DOI

Anne-Marie Byrne , Spiros Bekiaris, Gina Duggan, David Prichard, Murat Kirca, Stephen Finn, John V Reynolds, Dermot Kelleher and Aideen Long, Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion, British Journal of Cancer, 113, 2015, p1332-1342 Journal Article, 2015 DOI TARA - Full Text

Picardo SL, O'Brien MP, Feighery R, O'Toole D, Ravi N, O'Farrell NJ, O'Sullivan JN, Reynolds JV, A Barrett's esophagus registry of over 1000 patients from a specialist center highlights greater risk of progression than population-based registries and high risk of low grade dysplasia., Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, 28, (2), 2015, p121-126 Journal Article, 2015 TARA - Full Text DOI

Donohoe C.L, Conneely J.B, Zilbert N, Hennessy M, Schofield S, Reynolds J.V, Docemur Docemus: Peer-Assisted Learning Improves the Knowledge Gain of Tutors in the Highest Quartile of Achievement but Not Those in the Lowest Quartile, Journal of Surgical Education, 72, (6), 2015, p1139 - 1144 Journal Article, 2015 URL DOI

Mongan AM, Kalachand R, King S, O'Farrell NJ, Power D, Ravi N, Muldoon C, O'Byrne K, Reynolds JV, Outcomes in gastric and junctional cancer using neoadjuvant and adjuvant chemotherapy (epirubicin, oxaliplatin, and capecitabine) and radical surgery., Irish journal of medical science, 184, (2), 2015, p417-423 Journal Article, 2015 DOI

Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, Tucker A, Love S, Nanji M, deCaestecker J, Ferry D, Rathbone B, Hapeshi J, Barr H, Moayyedi P, Watson P, Zietek B, Maroo N, Gay L, Underwood T, Boulter L, McMurtry H, Monk D, Patel P, Ragunath K, Al Dulaimi D, Murray I, Koss K, Veitch A, Trudgill N, Nwokolo C, Rembacken B, Atherfold P, Green E, Ang Y, Kuipers EJ, Chow W, Paterson S, Kadri S, Beales I, Grimley C, Mullins P, Beckett C, Farrant M, Dixon A, Kelly S, Johnson M, Wajed S, Dhar A, Sawyer E, Roylance R, Onstad L, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Reid BJ, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Fitzgerald R, Whiteman DC, Risch HA, Levine DM, Vaughan TL, Verhaar AP, van den Brande J, Toxopeus EL, Spaander MC, Wijnhoven BP, van der Laan LJ, Krishnadath K, Wijmenga C, Trynka G, McManus R, Reynolds JV, O'Sullivan J, MacMathuna P, McGarrigle SA, Kelleher D, Vermeire S, Cleynen I, Bisschops R, Tomlinson I, Jankowski J, Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus., Gastroenterology, 148, (2), 2015, p367-78 Journal Article, 2015 TARA - Full Text DOI

Heckel L, Fennell K.M, Reynolds J, Osborne R.H, Chirgwin J, Botti M, Ashley D.M, Livingston P.M, Unmet needs and depression among carers of people newly diagnosed with cancer, European Journal of Cancer, 51, (14), 2015, p2049 - 2057 Journal Article, 2015 URL DOI

Walsh S.M, Maphango N, Egan J.J, Reynolds J.V, Successful surgical management of early esophageal cancer in a patient with cystic fibrosis post-bilateral lung transplantation, BMJ case reports, 2015, 2015, p210342- Journal Article, 2015 URL DOI

Conroy MJ, Dunne MR, Donohoe CL, Reynolds JV, Obesity-associated cancer: an immunological perspective, Proceedings of the Nutrition Society, 2015, p1-14 Journal Article, 2015 Other URL

Abdel-Latif MM, Kelleher D, Reynolds JV, Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinoma., European journal of cancer (Oxford, England : 1990), 51, (4), 2015, 464-472 Journal Article, 2015 DOI

Elliott J.A, Jackson S, King S, Mchugh R, Docherty N.G, Reynolds J.V, Le Roux C.W, Gut hormone suppression increases food intake after esophagectomy with gastric conduit reconstruction, Annals of Surgery, 262, (5), 2015, p824 - 830 Journal Article, 2015 DOI URL

Croghan, S., McCormack, O., Muldoon, C., Ravi, N., Reynolds, J.V., Metachronous adenocarcinoma of the remnant oesophagus 15 years following multimodal therapy, Irish Medical Journal, 108, (1), 2015, p22-3 Journal Article, 2015

El-Mashed S., O'Donovan T., Kay E., Abdallah A., Cathcart M., O'Sullivan J., O'Grady A., Reynolds J., O'Reilly S., O'Sullivan G., McKenna S., LC3B globular structures correlate with survival in esophageal adenocarcinoma, BMC Cancer, 15, (1), 2015, p582- Journal Article, 2015 DOI TARA - Full Text

Kavanagh ME, O'Sullivan KE, O'Hanlon C, O'Sullivan JN, Lysaght J, Reynolds JV, The esophagitis to adenocarcinoma sequence; the role of inflammation., Cancer letters, 345, (2), 2014, p182-9 Journal Article, 2014 TARA - Full Text DOI

Moran T, Lawlor P, Brennan M, Ravi N, Reynolds JV, Oesophageal manometry: 10-year audit from a specialist centre, and early experience with high-resolution manometry., Irish journal of medical science, 184, (2), 2014, p379-87 Journal Article, 2014 TARA - Full Text DOI

Elliott JA, McCormack O, Tchrakian N, Conlon N, Ryan CE, Lim KT, Ullah N, Mahmud N, Ravi N, McKiernan S, Feighery C, Reynolds JV, Eosinophilic ascites with marked peripheral eosinophilia: a diagnostic challenge., European journal of gastroenterology & hepatology, 26, (4), 2014, p478-84 Journal Article, 2014 TARA - Full Text DOI

Lynam-Lennon, N., Maher, S.G., Maguire, A., (...), Reynolds, J.V., O'Sullivan, J., Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma, PLoS ONE , 9, (6), 2014, pe100738- Journal Article, 2014 TARA - Full Text DOI

O'Sullivan KE, Reynolds JV, O'Hanlon C, O'Sullivan JN, Lysaght J, Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?, Journal of gastrointestinal cancer, 45, (1), 2014, p1-11 Journal Article, 2014 DOI

Mongan, A.M., Kalachand, R., King, S., (...), O'Byrne, K., Reynolds, J.V. , Outcomes in gastric and junctional cancer using neoadjuvant and adjuvant chemotherapy (epirubicin, oxaliplatin, and capecitabine) and radical surgery, Irish Journal of Medical Science, 184, (2), 2014, p417-423 Journal Article, 2014 DOI

Kavanagh, M.E., O'Sullivan, K.E., O'Hanlon, C., (...), Lysaght, J., Reynolds, J.V., The esophagitis to adenocarcinoma sequence; the role of inflammation, Cancer Letters, 345, (2), 2014, p182-189 Journal Article, 2014 DOI

Nur MM, Finn S, Reynolds JV, Identification of potential therapeutic molecular targets preferentially expressed by esophageal cancer cells., Expert review of anticancer therapy, 14, (3), 2014, p267-9 Journal Article, 2014 DOI

Donohoe CL, Reynolds JV, Defining a successful esophagectomy., Annals of surgery, 259, (5), 2014, pe82 Journal Article, 2014 TARA - Full Text DOI

O'Sullivan KE, Phelan JJ, O'Hanlon C, Lysaght J, O'Sullivan JN, Reynolds JV., The role of inflammation in cancer of the esophagus., Expert Reviews Gastroenterology Hepatology, 8, (7), 2014, p749 - 760 Journal Article, 2014 TARA - Full Text DOI

Valkenet K., Trappenburg J.C., Gosselink R., Sosef M.N., Willms J., Rosman C., Pieters H., Scheepers J.J., de Heus S.T., Reynolds J.V., Guinan EM., Ruurda J.P., Rodrigo E.H., Nafteux P., Fontaine M., Kouwenhoven E.A., Kerkemeyer M., van der Peet D.L., Hania S.W., van Hillegersberg R., Backx F.J. , Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (the PREPARE study): study protocol for a randomized controlled trial, Trials, 15, (1), 2014, p144- Journal Article, 2014 TARA - Full Text

. Donohoe CL, O'Farrell NJ, Doyle SL, Reynolds JV., The role of obesity in gastrointestinal cancer: evidence and opinion, Therap Adv Gastroenterol, 7, (1), 2014, p38-50 Journal Article, 2014 TARA - Full Text DOI

Lynam-Lennon N, Connaughton R, Carr E, Mongan AM, O'Farrell NJ, Porter RK, Brennan L, Pidgeon GP, Lysaght J, Reynolds JV, O'Sullivan J, Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma., BMC cancer, 14, 2014, p907 Journal Article, 2014 TARA - Full Text DOI

Elliott J.A, O'Farrell N.J, King S, Halpenny D, Malik V, Muldoon C, Johnston C, Reynolds J.V, Value of CT-PET after neoadjuvant chemoradiation in the prediction of histological tumour regression, nodal status and survival in oesophageal adenocarcinoma, British Journal of Surgery, 101, (13), 2014, p1702 - 1711 Journal Article, 2014 DOI URL

Howard JM, Cathcart MC, Healy L, Beddy P, Muldoon C, Pidgeon GP, Reynolds JV, Leptin and adiponectin receptor expression in oesophageal cancer., The British journal of surgery, 101, (6), 2014, p643-52 Journal Article, 2014 DOI TARA - Full Text

Lynam-Lennon N, Maher SG, Maguire A, Phelan J, Muldoon C, Reynolds JV, O'Sullivan J, Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma., PloS one, 9, (6), 2014, pe100738 Journal Article, 2014 DOI TARA - Full Text

Mc Cormack O, Reynolds J.V, Intermittent facial flushing and diarrhea, New England Journal of Medicine, 371, (3), 2014, p260- Journal Article, 2014 URL DOI

de Steur, W. O. Henneman, D. Allum, W. H. Dikken, J. L. van Sandick, J. W. Reynolds, J. Mariette, C. Jensen, L. Johansson, J. Kolodziejczyk, P. Hardwick, R. H. van de Velde, C. J. H., Common data items in seven European oesophagogastric cancer surgery registries: Towards a European Upper GI Cancer Audit (EURECCA Upper GI), European Journal of Surgical Oncology (EJSO), 40, (3), 2014, p325 - 329 Journal Article, 2014 TARA - Full Text

Valkenet K, Trappenburg JC, Gosselink R, Sosef MN, Willms J, Rosman C, Pieters H, Scheepers JJ, de Heus SC, Reynolds JV, Guinan E, Ruurda JP, Rodrigo EH, Nafteux P, Fontaine M, Kouwenhoven EA, Kerkemeyer M, van der Peet DL, Hania SW, van Hillegersberg R, Backx FJ, Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (PREPARE study): study protocol for a randomized controlled trial., Trials, 15, (1), 2014, p144 Journal Article, 2014 TARA - Full Text DOI

Da Mota, Benoit Fritsch, Virgile Varoquaux, Gaël Banaschewski, Tobias Barker, Gareth J. Bokde, Arun L. W. Bromberg, Uli Conrod, Patricia Gallinat, Jürgen Garavan, Hugh Martinot, Jean-Luc Nees, Frauke Paus, Tomas Pausova, Zdenka Rietschel, Marcella Smolka, Michael N. Ströhle, Andreas Frouin, Vincent Poline, Jean-Baptiste Thirion, Bertrand, Randomized parcellation based inference, NeuroImage, 2014 Journal Article, 2014

Mc Cormack O, Zaborowski A, King S, Healy L, Daly C, O"Farrell N, Donohoe CL, Ravi N, Reynolds JV, New-onset atrial fibrillation post-surgery for esophageal and junctional cancer: incidence, management, and impact on short- and long-term outcomes., Annals of surgery, 260, (5), 2014, p772-8; discussion 778 Journal Article, 2014 DOI

Phelan JJ, MacCarthy F, Feighery R, O'Farrell NJ, Lynam-Lennon N, Doyle B, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Differential expression of mitochondrial energy metabolism profiles across the metaplasia-dysplasia-adenocarcinoma disease sequence in Barrett's oesophagus., Cancer letters, 354, (1), 2014, p122-31 Journal Article, 2014 TARA - Full Text DOI

Horan M, Weitz A, Mc Cormack O, Muldoon C, Ravi N, Reynolds JV, Severe dysphagia, candidiasis, and an oesophageal mass, but over 50 biopsies negative for malignancy., Dysphagia, 29, (1), 2014, p109-12 Journal Article, 2014 DOI

Mc Cormack O, Reynolds JV, Images in clinical medicine. Intermittent facial flushing and diarrhea., The New England journal of medicine, 371, (3), 2014, p260 Journal Article, 2014 TARA - Full Text DOI

Lahiff C, Schilling C, Cathcart MC, Mulligan N, Doran P, Muldoon C, Murray D, Pidgeon GP, Reynolds JV, Macmathuna P, Prognostic significance of neuroepithelial transforming gene 1 in adenocarcinoma of the oesophagogastric junction., The British journal of surgery, 101, (2), 2014, p55-62 Journal Article, 2014 TARA - Full Text DOI

Martin-Smith JD, Larkin JO, Ravi N, Reynolds JV, Severe epigastric pain following a birthday party., Irish medical journal, 106, (1), 2013, p23 Journal Article, 2013 TARA - Full Text

Mc Cormack O, Cooney JM, Doherty CP, Muldoon C, Reynolds JV, Paraneoplastic limbic encephalitis from esophagogastric squamous cell carcinoma successfully managed by radical gastrectomy., Surgery, 154, (3), 2013, p638-40 Journal Article, 2013 DOI

Mongan AM, Malik V, Rowley S, Claxton Z, Muldoon C, O'Toole D, Ravi N, Reynolds JV, Presentation and management of gastrointestinal stromal tumours., Irish medical journal, 106, (6), 2013, p176-9 Journal Article, 2013 TARA - Full Text

Donohoe CL, O'Farrell NJ, Grant T, King S, Clarke L, Muldoon C, Reynolds JV, Classification of pathologic response to neoadjuvant therapy in esophageal and junctional cancer: assessment of existing measures and proposal of a novel 3-point standard., Annals of surgery, 258, (5), 2013, p784-92; discussion 792 Journal Article, 2013 DOI

McCarron E, McCormack O, Cronin T, McGowan A, Healy ML, O'Rourke D, Crushell E, Ravi N, Reynolds JV, Management of maple syrup urine disease in the peri-operative period., Irish medical journal, 106, (9), 2013, p277-8 Journal Article, 2013 TARA - Full Text

Awan FN, Zulkifli MS, McCormack O, Manzoor T, Ravi N, Mehigan B, Reynolds JV, Factors involved in unplanned admissions from general surgical day-care in a modern protected facility., Irish medical journal, 106, (5), 2013, p153-4 Journal Article, 2013 TARA - Full Text

Fitzgerald C, Mc Cormack O, Reynolds JV, Severe intractable postprandial chest pain., JAMA : the journal of the American Medical Association, 310, (4), 2013, p424-7 Journal Article, 2013 DOI

Donohoe CL, Reynolds JV, Oesophageal Perforations Commentary., Digestive surgery, 30, (1), 2013, p26-27 Journal Article, 2013 DOI

O'Farrell NJ, Reynolds JV, Ravi N, Larkin JO, Malik V, Wilson GF, Muldoon C, O'Toole D, Evolving changes in the management of early oesophageal adenocarcinoma in a tertiary centre., Irish journal of medical science, 182, (3), 2013, p363-9 Journal Article, 2013 DOI

Doyle SL, Bennett AM, Donohoe CL, Mongan AM, Howard JM, Lithander FE, Pidgeon GP, Reynolds JV, Lysaght J, Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research., Nutrition research (New York, N.Y.), 33, (3), 2013, p171-9 Journal Article, 2013 DOI

Mc Cormack O, Meaney JF, Reynolds JV, Resolving sclerosing mesenteritis., Surgery, 153, (6), 2013, p879-80 Journal Article, 2013 DOI

Allott EH, Lysaght J, Cathcart MC, Donohoe CL, Cummins R, McGarrigle SA, Kay E, Reynolds JV, Pidgeon GP, MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation., Molecular carcinogenesis, 52, (2), 2013, p144-54 Journal Article, 2013 DOI

O'Sullivan KE, Larkin JO, Guiney M, Reynolds JV, Necrotising pancreatitis presenting as a painful mass in the groin and sepsis., BMJ case reports, 2013, 2013 Journal Article, 2013 DOI

DeVault K, McMahon BP, Celebi A, Costamagna G, Marchese M, Clarke JO, Hejazi RA, McCallum RW, Savarino V, Zentilin P, Savarino E, Thomson M, Souza RF, Donohoe CL, O'Farrell NJ, Reynolds JV, Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus., Annals of the New York Academy of Sciences, 1300, 2013, p278-95 Journal Article, 2013 DOI

O'Farrell NJ, Donohoe CL, Muldoon C, Costelloe JM, King S, Ravi N, Reynolds JV, Lack of Independent Significance of a Close (<1 mm) Circumferential Resection Margin Involvement in Esophageal and Junctional Cancer., Annals of surgical oncology, 20, (8), 2013, p2727-33 Journal Article, 2013 DOI

O'Sullivan KE, Moriarty AR, Larkin JO, Reynolds JV, Curative surgical management of isolated adrenal recurrence of oesophageal adenocarcinoma., BMJ case reports, 2013, 2013, p00-0 Journal Article, 2013 DOI

O'Farrell NJ, Malik V, Donohoe CL, Johnston C, Muldoon C, Reynolds JV, O'Toole D, Appraisal of staging endoscopic ultrasonography in a modern high-volume esophageal program., World journal of surgery, 37, (7), 2013, p1666-72 Journal Article, 2013 DOI

Fang Y, Chen X, Bajpai M, Verma A, Das KM, Souza RF, Garman KS, Donohoe CL, O'Farrell NJ, Reynolds JV, Dvorak K, Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma., Annals of the New York Academy of Sciences, 1300, 2013, p187-99 Journal Article, 2013 DOI

Costelloe J, Mc Cormack O, Reynolds JV, Dissecting intramural hematoma of the esophagus., Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, 26, (3), 2013, p346 Journal Article, 2013 TARA - Full Text DOI

Fitzgerald C, Mc Cormack O, Awan F, Elliott J, Ravi N, Reynolds JV, Incarcerated thoracic gastric herniation after nephrectomy: a report of two cases., Case reports in surgery, 2013, 2013, p896452 Journal Article, 2013 DOI TARA - Full Text

Guevara G, O'Connor E, McCormack O, Harmon M, Finn S, Muldoon C, Ravi N, Reynolds JV, Diffuse oesophageal leiomyomatosis., ANZ journal of surgery, 2013 Journal Article, 2013 TARA - Full Text DOI

Moriarity AR, Larkin JO, O'Sullivan KE, Ravi N, Reynolds JV, Spontaneous perforation of the esophagus in a patient with achalasia., The Annals of thoracic surgery, 96, (4), 2013, p1456-7 Journal Article, 2013 DOI

Picardo SL, Maher SG, O'Sullivan JN, Reynolds JV, Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer., Digestive surgery, 29, (3), 2012, p251-60 Journal Article, 2012 DOI

Reynolds JV, Donohore CL, McGillycuddy E, Ravi N, O'Toole D, O'Byrne K, Hollwyood D. , Evolving progress in oncologic and operative outcomes for esophageal and junctional cancer: Lessons from the experience of a high-volume esophageal center, The Journal of Thoracic and Cardiovascular Surgery, 145, (3), 2012, p1130-1137 Journal Article, 2012 DOI

O'Kelly F, Lim KT, Hayes B, Shields W, Ravi N, Reynolds JV, The Houdini effect--an unusual case of blunt abdominal trauma resulting in perforative appendicitis., Irish medical journal, 105, (3), 2012, p86-7 Journal Article, 2012

Doyle SL, Donohoe CL, Lysaght J, Reynolds JV, Viseral obesity, metabolic syndrome, insulin resistance and cancer, Proceedings of the Nutrition Society, 71, (1), 2012, p181-9 Journal Article, 2012 DOI

SL Doyle, C Donohoe, S Finn, J Howard, FE Lithander, JV Reynolds, G Pidgeon, J Lysaght , IGF-1 and its Receptor in Esophageal Cancer: Association with Adenocarcinoma and Visceral Obesity, American Journal of Gastroenterology, 107, 2012, p196 - 204 Journal Article, 2012 DOI URL

Crosby DA, Donohoe CL, Fitzgerald L, Muldoon C, Hayes B, O'Toole D, Reynolds JV, Gastric neuroendocrine tumours., Digestive surgery, 29, (4), 2012, p331-48 Journal Article, 2012 DOI

Healy LA, Howard JM, Ryan AM, Beddy P, Mehigan B, Stephens R, Reynolds JV, Metabolic syndrome and leptin are associated with adverse pathological features in male colorectal cancer patients., Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 14, (2), 2012, p157-65 Journal Article, 2012 DOI

O'Flaherty JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K, The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7, (12), 2012, p1880-90 Journal Article, 2012 DOI

Su Z, Gay LJ, Strange A, Palles C, Band G, Whiteman DC, Lescai F, Langford C, Nanji M, Edkins S, van der Winkel A, Levine D, Sasieni P, Bellenguez C, Howarth K, Freeman C, Trudgill N, Tucker AT, Pirinen M, Peppelenbosch MP, van der Laan LJ, Kuipers EJ, Drenth JP, Peters WH, Reynolds JV, Kelleher DP, McManus R, Grabsch H, Prenen H, Bisschops R, Krishnadath K, Siersema PD, van Baal JW, Middleton M, Petty R, Gillies R, Burch N, Bhandari P, Paterson S, Edwards C, Penman I, Vaidya K, Ang Y, Murray I, Patel P, Ye W, Mullins P, Wu AH, Bird NC, Dallal H, Shaheen NJ, Murray LJ, Koss K, Bernstein L, Romero Y, Hardie LJ, Zhang R, Winter H, Corley DA, Panter S, Risch HA, Reid BJ, Sargeant I, Gammon MD, Smart H, Dhar A, McMurtry H, Ali H, Liu G, Casson AG, Chow WH, Rutter M, Tawil A, Morris D, Nwokolo C, Isaacs P, Rodgers C, Ragunath K, MacDonald C, Haigh C, Monk D, Davies G, Wajed S, Johnston D, Gibbons M, Cullen S, Church N, Langley R, Griffin M, Alderson D, Deloukas P, Hunt SE, Gray E, Dronov S, Potter SC, Tashakkori-Ghanbaria A, Anderson M, Brooks C, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood N, Trynka G, Wijmenga C, Cazier JB, Atherfold P, Nicholson AM, Gellatly NL, Glancy D, Cooper SC, Cunningham D, Lind T, Hapeshi J, Ferry D, Rathbone B, Brown J, Love S, Attwood S, MacGregor S, Watson P, Sanders S, Ek W, Harrison RF, Moayyedi P, de Caestecker J, Barr H, Stupka E, Vaughan TL, Peltonen L, Spencer CC, Tomlinson I, Donnelly P, Jankowski JA, Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus., Nature genetics, 44, (10), 2012, p1131-6 Journal Article, 2012 DOI

Ryan, A.M. , Healy, L.A., Reynolds, J.V. , Reply to letter, questions about the evidence regarding the benefits of enteral nutrition enriched with eicosapentaenoic acid in esophageal cancer surgery, 2012, - e16 Miscellaneous, 2012 DOI

Costelloe J, O'Connell C, Mc Cormack O, Maccarthy F, Halpenny DF, Shatwan R, Muldoon C, Ravi N, Reynolds JV, Malignant Gastrocolic Fistula as a Late Complication of Radiation Therapy., Journal of gastrointestinal cancer, 43, (SUPPL. 1), 2012, pS269-S272 Journal Article, 2012 DOI

Hötte GJ, Linam-Lennon N, Reynolds JV, Maher SG, Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance., Radiation research, 177, (3), 2012, p272-9 Journal Article, 2012 DOI

Mc Cormack O, Timlin M, Mc Gowan A, Healy ML, Ravi N, Reynolds JV, Management of squamous cell cancer of the oesophagus in a patient with a polyglandular endocrinopathy (APECED) and achalasia., Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 16, (10), 2012, p1963-6 Journal Article, 2012 DOI

Lahiff C, Shields W, Cretu I, Mahmud N, McKiernan S, Norris S, Silke B, Reynolds JV, O'Toole D., Upper gastrointestinal bleeding: predictors of risk in a mixed patient group including variceal and nonvariceal haemorrhage, European Journal of Gastroenterology & Hepatology, 24, (2), 2012, p149-54 Journal Article, 2012 DOI

Geoghegan AR, Donohoe CL, Reynolds JV, Acute intestinal failure in surgical patients: an audit of incidence, management, and outcomes in an Irish hospital, and compliance with ASGBI guidelines, 181, 4, 2012, p467-71 Journal Article, 2012 DOI

Babar M, Ryan AW, Anderson LA, Segurado R, Turner G, Murray LJ, Murphy SJ, Johnston BT, Comber H, Reynolds JV, McManus R, Genes of the Interleukin-18 pathway are associated with susceptibility to Barrett's Esophagus and Esophageal Adenocarcinoma, American Journal of Gastroenterology, 107, (9), 2012, p1331-1341 Journal Article, 2012 DOI

Donohoe CL, Feeney C, Carey MF, Reynolds JV., Perioperative evaluation of the obese patient, Journal of Clinical Anesthesia, 2012 Review Article, 2012

Naidoo J, O'Toole T, Kennedy MJ, Reynolds JV, A single institution experience of streptozotocin/fluorouracil combination chemotherapy: a case series, Irish Journal of Medical Science, 181, (2), 2012, p211-4 Journal Article, 2012 DOI

Donohoe CL, Doyle SL, McGarrigle S, Cathcart MC, Daly E, O'Grady A, Lysaght J, Pidgeon GP, Reynolds JV., Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma, British Journal of Surgery, 99, (3), 2012, p387-96 Journal Article, 2012 DOI

Allott EH, Oliver E, Lysaght J, Gray SG, Reynolds JV, Roche HM, Pidgeon GP, The SGBS cell strain as a model for the in vitro study of obesity and cancer., Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 14, (10), 2012, p774-82 Journal Article, 2012 DOI

Donohoe CL, O'Farrell NJ, Ravi N, Reynolds JV, Evidence-based selective application of transhiatal esophagectomy in a high-volume esophageal center., World journal of surgery, 36, (1), 2012, p98-103 Journal Article, 2012 DOI

Allott EH, Morine MJ, Lysaght J, McGarrigle SA, Donohoe CL, Reynolds JV, Roche HM, Pidgeon GP, Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis., Clinical and translational gastroenterology, 3, 2012, pe12 Journal Article, 2012 DOI TARA - Full Text

Malik V, Johnston C, Donohoe C, Claxton Z, Lucey J, Ravi N, Reynolds JV, (18)F-FDG PET-detected synchronous primary neoplasms in the staging of esophageal cancer: incidence, cost, and impact on management., Clinical nuclear medicine, 37, (12), 2012, p1152-8 Journal Article, 2012 DOI

Mary-Clare Cathcart, Kenneth J. O'Byrne, John V. Reynolds, Jacintha O' Sullivan, Graham P. Pidgeon, COX-Derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1825, (1), 2012, p49-63 Journal Article, 2012 TARA - Full Text

Iland HJ, Bradstock K, Supple SG, Catalano A, Collins M, Hertzberg M, Browett P, Grigg A, Firkin F, Hugman A, Reynolds J, Di Iulio J, Tiley C, Taylor K, Filshie R, Seldon M, Taper J, Szer J, Moore J, Bashford J, Seymour JF, All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)., Blood, 120, (8), 2012, p1570-80; quiz 1752 Journal Article, 2012 DOI

Donohoe CL, Macgillicuddy E, Reynolds JV, The impact of young age on outcomes in esophageal and junctional cancer, Diseases of the Esophagus, 24, (8), 2011, p560-568 Journal Article, 2011 DOI

Stephen G. Maher, Dermot T. McDowell, Ben C. Collins, Cian Muldoon, William M. Gallagher, John V. Reynolds, Serum proteomic profiling reveals that pre-treatment complement protein levels are predictive of esophageal cancer patient response to neo-adjuvant chemoradiation, Annals of Surgery, 254, (5), 2011, p809 - 817 Journal Article, 2011

Claire L. Donohoe, Aoife M. Ryan, and John V. Reynolds, Cancer Cachexia:Mechanisms and Clinical Implications, Gastroenterology Research and Practice, 2011, (601434), 2011, p13 Review Article, 2011 TARA - Full Text

Donohoe CL, Doyle SL, Reynolds JV, Visceral adiposity, insulin resistance and cancer risk, Diabetology & Metabolic Syndrome , 3, (12), 2011 Journal Article, 2011 TARA - Full Text URL DOI

Loh JK, O'Kelly F, Lim KT, Shields W, Ravi N, Keeling NP, Reynolds JV, Triple-vessel mesenteric ischaemia presenting with gastric ulceration., Irish journal of medical science, 180, (2), 2011, p537-40 Journal Article, 2011 DOI

Maher SG, Reynolds JV, Basic concepts of inflammation and its role in carcinogenesis., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 185, 2011, p1-34 Journal Article, 2011 DOI

Ryan AM, Duong M, Healy L, Ryan SA, Parekh N, Reynolds JV, Power DG, Obesity, metabolic syndrome and esophageal adenocarcinoma: epidemiology, etiology and new targets., Cancer epidemiology, 35, (4), 2011, p309-19 Journal Article, 2011 DOI

Lysaght J, Allott EH, Donohoe CL, Howard JM, Pidgeon GP, Reynolds JV., T lymphocyte activation in visceral adipose tissue of patients with oesophageal adenocarcinoma., British Journal of Surgery, 98, (7), 2011, p964 - 974 Journal Article, 2011 DOI

Mc Ardle A, Conneely JB, Ravi N, Reynolds JV, Duodenal duplication cyst presenting with gastric outlet obstruction in an adult male, Endoscopy, 43, 2011, pe352-3 Journal Article, 2011

Howard JM, Ryan L, Lim KT, Reynolds JV, Oesophagectomy in the management of end-stage achalasia - case reports and a review of the literature., International journal of surgery (London, England), 9, (3), 2011, p204-8 Journal Article, 2011 DOI

Donohoe CL, Nguyen M, Cook J, Murray SG, Chen N, Zaki F, Mehigan BJ, McCormick PH, Reynolds JV, Fast-track protocols in colorectal surgery., The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 9, (2), 2011, p95-103 Journal Article, 2011 DOI

J. Lysaght, E.P. van der Stok, E.H. Allott, R. Casey, C.L. Donohoe, J.M. Howard, S.A. McGarrigle, N. Ravi, J.V. Reynolds, G.P. Pidgeon, Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue, Cancer Letters, 312, (1), 2011, p62-72 Journal Article, 2011 TARA - Full Text

Larkin JO, Moriarity AR, O'Mahony D, Meaney J, Ravi N, Reynolds JV, Gallstone ileus in evolution., ANZ journal of surgery, 81, (4), 2011, p287-8 Journal Article, 2011 DOI

Donohoe Cl, O'Farrell NJ, Ravi N, Reynolds JV, Evidence-based selective application of transhiatal esophagectomy in a high-volume esophageal center, World Journal of Surgery, 36, (1), 2011, p98-103 Journal Article, 2011 DOI

Feeney C, Reynolds JV, Hussey J, Preoperative physical activity levels and postoperative pulmonary complications post-esphagectomy, Diseases of the Esophagus, 24, 2011, p489 - 494 Journal Article, 2011

Larkin JO, Cooke F, Ravi N, Reynolds JV, Internal hernia following total gastrectomy with Roux-en-Y reconstruction., Annals of the Royal College of Surgeons of England, 93, (6), 2011, pe71-3 Journal Article, 2011 DOI TARA - Full Text

Reynolds JV, Donohoe CL, Ravin N, O'Byrne K, Hollywood D., Modern operative and oncological outcome in oesophagel cancer, Irish Medical Journal, 104, 2011, p235-9 Journal Article, 2011 TARA - Full Text

Paszko E, Ehrhardt C, Senge MO, Kelleher DP, Reynolds JV, Nanodrug applications in photodynamic therapy., Photodiagnosis and photodynamic therapy, 8, (1), 2011, p14-29 Journal Article, 2011 DOI TARA - Full Text

Reynolds JV, Donohoe CL, Doyle SL, Diet, obesity and cancer., Irish journal of medical science, 180, (2), 2011, p521-7 Journal Article, 2011 DOI

Donohoe CL, McGillycuddy E, Reynolds JV, Long-term health-related quality of life for disease-free esophageal cancer patients., World journal of surgery, 35, (8), 2011, p1853-60 Journal Article, 2011 DOI

Philbin DM, Larkin JO, Ravi N, Wilson G, Reynolds JV, Recurrent melaena in a 21-year-old female., ANZ journal of surgery, 81, (3), 2011, p181-2 Journal Article, 2011 DOI

Carroll PA, Healy L, Lysaght J, Boyle T, Reynolds JV, Kennedy MJ, Pidgeon G, Connolly EM., Influence of the metabolic syndrome on leptin and leptin receptor in breast cancer., Molecular Carcinogenesis, 50, (8), 2011, p643 - 651 Journal Article, 2011 DOI

Mulholland HG, Murray LJ, Anderson LA, Cantwell MM, Vitamin D, calcium and dairy intake, and risk of oesophageal adenocarcinoma and its precursor conditions., The British journal of nutrition, 106, (5), 2011, p732-41 Journal Article, 2011 TARA - Full Text DOI

Howard JM, Beddy P, Ennis D, Keogan M, Pidgeon GP, Reynolds JV, Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma., The British journal of surgery, 97, (7), 2010, p1020-7 Journal Article, 2010

Byrne M, Reynolds JV, O'Donnell JS, Keogan M, White B, Byrne M, Murphy S, Maher SG, Pidgeon GP, Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery., British Journal of Cancer, 102, (1), 2010, p73-9 Journal Article, 2010 TARA - Full Text DOI

Doyle SL, Lysaght J, Reynolds JV, Obesity and post-operative complications in patients undergoing non-bariatric surgery., Obesity reviews : an official journal of the International Association for the Study of Obesity, 11, (12), 2010, p875-86 Journal Article, 2010

O'Kelly F, Lim KT, Ravi N, Mahmud N, Reynolds JV, The value of double balloon enteroscopy in diagnosing blue rubber bleb naevus syndrome: a case report., Cases Journal, 3, (29), 2010 Journal Article, 2010 URL TARA - Full Text DOI

Power DG, Reynolds JV, Localized adenocarcinoma of the esophagogastric junction--is there a standard of care?, Cancer treatment reviews, 36, (5), 2010, p400-9 Journal Article, 2010

Healy LA, Ryan AM, Carroll P, Ennis D, Crowley V, Boyle T, Kennedy MJ, Connolly E, Reynolds JV., Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer, Clinical Oncology, 22, (4), 2010, p281-288 Journal Article, 2010

Howard JM, Pidgeon GP, Reynolds JV, Leptin and gastrointestinal malignancies , Obesity Reviews, 11, (12), 2010, p863-874 Journal Article, 2010

Reynolds JV, Murphy TJ, Ravi N, Multimodality therapy for adenocarcinoma of the esophagus, gastric cardia, and upper gastric third., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 182, 2010, p155-66 Journal Article, 2010

Beddy P, Howard J, McMahon C, Knox M, de Blacam C, Ravi N, Reynolds JV, Keogan MT, Association of visceral adiposity with oesophageal and junctional adenocarcinomas., The British journal of surgery, 97, (7), 2010, p1028-34 Journal Article, 2010

Reynolds JV, Ravi N, Muldoon C, Larkin JO, Rowley S, O'Byrne K, Hollywood D, O'Toole D, Differential pathologic variables and outcomes across the spectrum of adenocarcinoma of the esophagogastric junction., World journal of surgery, 34, (12), 2010, p2821-9 Journal Article, 2010 DOI

Donohoe CL, Reynolds JV, Short bowel syndrome , Surgeon, 8, 2010, p270-9 Journal Article, 2010

Murphy SJ, Anderson LA, Ferguson HR, Johnston BT, Watson PR, McGuigan J, Comber H, Reynolds JV, Murray LJ, Cantwell MM, Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus., The Journal of nutrition, 140, (10), 2010, p1757-63 Journal Article, 2010

Lynam-Lennon N, Reynolds JV, Pidgeon GP, Lysaght J, Marignol L, Maher SG, Alterations in DNA repair efficiency are involved in the radioresistance of esophageal adenocarcinoma., Radiation research, 174, (6), 2010, p703 - 711 Journal Article, 2010 DOI

Malik V, Lucey JA, Duffy GJ, Wilson L, McNamara L, Keogan M, Gillham C, Reynolds JV, Early repeated 18F-FDG PET scans during neoadjuvant chemoradiation fail to predict histopathologic response or survival benefit in adenocarcinoma of the esophagus., Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51, (12), 2010, p1863-9 Journal Article, 2010

Duggan SP, Behan FM, Kirca M, Smith S, Reynolds JV, Long A, Kelleher D, An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, down regulated in Barrett's oesophagus, which regulates NF-kB activation and cytokine levels., Carcinogenesis, 5, 2010, p936 - 945 Journal Article, 2010 DOI URL

Healy LA, Ryan AM, Sutton E, Younger K, Mehigan B, Stephens R, Reynolds JV, Impact of obesity on surgical and oncological outcomes in the management of colorectal cancer., International journal of colorectal disease, 25, (11), 2010, p1293-9 Journal Article, 2010

Mary-Clare Cathcart, John V. Reynolds, Kenneth J. O'Byrne, Graham P. Pidgeon, The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer , Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1805, (2), 2010, p153-166 Journal Article, 2010 TARA - Full Text

Jayaprakash N, O'Kelly F, Lim KT, Reynolds JV., Management of synchronous adenocarcinoma of the esophago-gastric junction and ampulla of Vater: case report of a surgically challenging condition, Patient Safety in Surgery, 3, (23), 2009 Journal Article, 2009 DOI TARA - Full Text

Babar M, Abdel-Latif MM, Ravi N, Murphy A, Byrne PJ, Kelleher D, Reynolds JV., Pilot translational study of dietary vitamin C supplementation in Barrett's esophagus., Dis Esophagus, 23, (3), 2009 Journal Article, 2009

Martin-Smith JD, Larkin JO, O'Connell F, Ravi N, Reynolds JV , Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report, BMC Surgery, 9, (20), 2009 Journal Article, 2009 TARA - Full Text DOI

O'Kelly F, Lim KT, Cooke F, Ravi N, Reynolds JV., An unusual presentation of Boerhaave Syndrome: a case report, Cases Journal, 2, (8000), 2009 Journal Article, 2009 TARA - Full Text DOI

Stephen G. Maher, Charles M. Gillham, Shane P. Duggan, Paul C. Smyth, Nicola Miller, Cian Muldoon, Kenneth J. O'Byrne, Orla M. Sheils, Donal Hollywood, John V. Reynolds, Gene expression analysis of diagnostic biopsies predicts pathological response to neoadjuvant chemoradiotherapy of esophageal cancer., Annals of surgery, 250, (5), 2009, p729-37 Journal Article, 2009 DOI

Smith FM, Gallagher WM, Fox E, Stephens RB, Rexhepaj E, Petricoin EF 3rd, Liotta L, Kennedy MJ, Reynolds JV, Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy, Annals of Surgery, 245, (2), 2007, p259 - 266 Journal Article, 2007 URL

O'Riordan JM, Rowley S, Murphy JO, Ravi N, Byrne PJ, Reynolds JV, Impact of Solitary Involved Lymph Node on Outcome in Localized Cancer of the Esophagus and Esophagogastric Junction , Journal of Gastrointestinal Surgery, 11, (4), 2007, p493 - 499 Journal Article, 2007 URL

Malik V, Keogan M, Gilham C, Duffy G, Ravi N, Reynolds JV, FDG-PET scanning in teh management of cancer of the oesophagus and oesophagogastric junction: early experience with 100 consecutive cases, Irish Journal of Medical Science, 175, (4), 2006, p48 - 54 Journal Article, 2006 URL

MacGuill M, Mulligan E, Ravi N, Rowley S, Byrne PJ, Hollywood D, Kennedy J, Keeling PN, Reynolds JV. , Clinicopathologic factors predicting complete pathological response to neoadjuvant chemoradiotherapy in esophageal cancer., Diseases of the Esophagus, 19, (4), 2006, p273 - 276 Journal Article, 2006 URL

Anderson LA, Johnston BT, Watson RG, Murphy SJ, Ferguson HR, Comber H, McGuigan J, Reynolds JV, Murray LJ. , Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence., Cancer Research, 66, (9), 2006, p4975 - 4982 Journal Article, 2006 URL

Abdel-Latif MM, Windle H, Terres A, Eidhin DN, Kelleher D, Reynolds JV, Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells, Journal of Gastrointestinal Surgery, 10, (4), 2006, p551 - 562 Journal Article, 2006 URL

Prichard R, Butt J, Al-Sariff N, Frohlich S, Murphy S, Manning B, Ravi N, Reynolds JV, Management of spontaneous rupture of the oesophagus (Boerhaave's syndrome): single centre experience of 18 cases, Irish Journal of Medical Science, 175, (4), 2006, p66 - 70 Journal Article, 2006 URL

Gillham CM, Lucey JA, Keogan M, Duffy GJ, Malik V, Raouf AA, O'Byrne K, Hollywood D, Muldoon C, Reynolds JV, (18)FDG uptake during induction chemoradiation for oesophageal cancer fails to predict histomorphological tumour response., British Journal of Cancer, 95, (9), 2006, p1174 - 1179 Journal Article, 2006 URL

Reynolds JV, Ravi N, Hollywood D, Kennedy Mj, Rowley S, Ryan A, Hughes N, Carey M, Byrne P, Neoadjuvant chemoradiation may increase the risk of respiratory complications and sepsis after transthoracic esophagectomy, Journal of Thoracic and Cardiovascular Surgery, 132, (3), 2006, p549 - 555 Journal Article, 2006 URL

Byrne PJ, Power C, Lawlor P, Ravi N, Reynolds JV, Laryngopharyngeal reflux in patients with symptoms of gastroesophageal reflux disease., Diseases of the Esophagus, 19, (5), 2006, p377 - 381 Journal Article, 2006 URL

Reynolds JV, McLaughlin R, Moore J, Rowley S, Ravi N, Byrne PJ. , Prospective evaluation of quality of life in patients with localized oesophageal cancer treated by multimodality therapy or surgery alone., The British Journal of Surgery, 93, (9), 2006, p1084 - 1090 Journal Article, 2006 URL

Ryan AM, Rowley SP, Healy LA, Flood PM, Ravi N, Reynolds JV. , Post-oesophagectomy early enteral nutrition via a needle catheter jejunostomy: 8-year experience at a specialist unit., Clinical Nutrition, 25, (3), 2006, p386 - 393 Journal Article, 2006 URL

Mahmood Z, Byrne PJ, McMahon BP, Murphy EM, Arfin Q, Ravi N, Weir DG, Reynolds JV. , Comparison of transesophageal endoscopic plication (TEP) with laparoscopic Nissen fundoplication (LNF) in the treatment of uncomplicated reflux disease., The American Journal of Gastroenterology, 101, (3), 2006, p431 - 436 Journal Article, 2006 URL

Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D., Low pH results in co-ordinate regulation of gene expression in oesophageal cells, Carcinogenesis, 27, (2), 2006, p319 - 327 Journal Article, 2006 DOI TARA - Full Text

Smith FM, Reynolds JV, Miller N, Stephens RB, Kennedy MJ, Pathological and molecular predictors of the response of rectal cancer to neoadjuvant radiochemotherapy., European Journal of Surgical Oncology, 32, (1), 2006, p55 - 64 Journal Article, 2006 URL

Ryan AM, Rowley SP, Fitzgerald AP, Ravi N, Reynolds JV. , Adenocarcinoma of the oesophagus and gastric cardia: male preponderance in association with obesity., European Journal of Cancer, 42, (8), 2006, p1151 - 1158 Journal Article, 2006 URL

Ravi N, Stuart RC, Byrne PJ, Reynolds JV. , Effect of physical exercise on esophageal motility in patients with esophageal disease., Diseases of the Esophagus, 18, (6), 2005, p374 - 377 Journal Article, 2005 URL

Abdel-Latif MM, Raouf AA, Sabra K, Kelleher D, Reynolds JV, Vitamin C enhances chemosensitization of esophageal cancer cells in vitro, Journal of Chemotherapy, 17, (5), 2005, p539 - 549 Journal Article, 2005 URL

Jabbar A, Reynolds JV, Plunkett PK, Stab to second intercostal space: a bubbling extrapleural wound., Èmergency Medicine Journal, 22, (12), 2005, p916 - 918 Journal Article, 2005 URL

E. D. Mulligan, B. Dunne, M. Griffin, N. Keeling and J. V. Reynolds, Margin involvement and outcome in oesophageal carcinoma: a 10-year experience in a specialist unit, European journal of surgical oncology, 30, (3), 2004, p313-7 Journal Article, 2004 URL

J. M. O'Riordan, P. J. Byrne, N. Ravi, P. W. Keeling and J. V. Reynolds, Long-term clinical and pathologic response of Barrett's esophagus after antireflux surgery, American journal of surgery, 188, (1), 2004, p27-33 Journal Article, 2004 URL

J. M. O'Riordan, O. N. Tucker, P. J. Byrne, G. S. McDonald, N. Ravi, P. W. Keeling and J. V. Reynolds, Factors influencing the development of Barrett's epithelium in the esophageal remnant postesophagectomy, The American journal of gastroenterology, 99, (2), 2004, p205-11 Journal Article, 2004 URL

P. M. Lawlor, J. A. McCullough, P. J. Byrne and J. V. Reynolds, Gastric myoelectrical activity post-chemoradiotherapy and esophagectomy: a prospective study using subscapular surface recording, Diseases of the esophagus, 17, (1), 2004, p76-80 Journal Article, 2004 URL

M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of surgery, 239, (4), 2004, p491-500 Journal Article, 2004 URL

K. J. Sweeney, M. R. Kell, C. Coates, T. Murphy and J. V. Reynolds, Serum antigen(s) drive the proinflammatory T cell response in acute pancreatitis, The British journal of surgery, 90, (3), 2003, p313-9 Journal Article, 2003 URL

Z. Mahmood, B. P. McMahon, Q. Arfin, P. J. Byrne, J. V. Reynolds, E. M. Murphy and D. G. Weir, Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up, Gut, 52, (1), 2003, p34-9 Journal Article, 2003 URL

A. A. Raouf, D. A. Evoy, E. Carton, E. Mulligan, M. M. Griffin and J. V. Reynolds, Loss of Bcl-2 expression in Barrett's dysplasia and adenocarcinoma is associated with tumor progression and worse survival but not with response to neoadjuvant chemoradiation, Diseases of the esophagus, 16, (1), 2003, p17-23 Journal Article, 2003 URL

E. M. Connolly, E. Gaffney and J. V. Reynolds, Gastrointestinal stromal tumours, The British journal of surgery, 90, (10), 2003, p1178-86 Journal Article, 2003 URL

P. J. Byrne, E. D. Mulligan, J. O'Riordan, P. W. Keeling and J. V. Reynolds, Impaired visceral sensitivity to acid reflux in patients with Barrett's esophagus. The role of esophageal motility*, Diseases of the esophagus, 16, (3), 2003, p199-203 Journal Article, 2003 URL

J. A. McCullough, D. Evoy, K. J. Sweeney, C. Meyers, N. Ravi, N. Keeling, P. J. Byrne and J. V. Reynolds, D2 lymphadenectomy in the management of gastric cancer, Irish journal of medical science, 172, (3), 2003, p132-5 Journal Article, 2003 URL

K. J. Sweeney, D. Evoy, S. Sultan, C. Coates, D. J. Moore, D. G. Shanik, M. R. Kell and J. V. Reynolds, Endovascular approach to abdominal aortic aneurysms limits the postoperative systemic immune response, European journal of vascular and endovascular surgery, 23, (4), 2002, p303-8 Journal Article, 2002 URL

J. P. McGrath, M. Browne, C. Riordan, N. Ravi and J. V. Reynolds, Expandable metal stents in the palliation of malignant dysphagia and oesophageal-respiratory fistulae, Irish medical journal, 94, (9), 2001, p270-2 Journal Article, 2001 URL

P. M. Lawlor, J. A. McCullough, P. J. Byrne and J. V. Reynolds, Electrogastrography: a non-invasive measurement of gastric function, Irish journal of medical science, 170, (2), 2001, p126-31 Journal Article, 2001 URL

B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British journal of cancer, 85, (10), 2001, p1499-503 Journal Article, 2001 URL

A. Raouf, D. Evoy, E. Carton, E. Mulligan, M. Griffin, E. Sweeney and J. V. Reynolds, Spontaneous and inducible apoptosis in oesophageal adenocarcinoma, British journal of cancer, 85, (11), 2001, p1781-6 Journal Article, 2001 URL

K. J. Sweeney, I. Rowe, P. Lawlor, P. Byrne and J. V. Reynolds, The isolated hypertensive lower oesophageal sphincter: audit in a specialist unit, Irish medical journal, 93, (8), 2000, p232-4 Journal Article, 2000 URL

E. D. Mulligan, T. Purcell, P. Lawlor, J. V. Reynolds and P. J. Byrne, Symptoms are a poor indication of severity of reflux in Barrett's oesophagus, The British journal of surgery, 87, (3), 2000, p362-73 Journal Article, 2000 URL

E. Carton, E. D. Mulligan, P. W. Keeling, A. Tanner, G. McDonald and J. V. Reynolds, Specialized intestinal metaplasia: analysis of prevalence, risk factors and association with gastro-oesophageal reflux disease, The British journal of surgery, 87, (3), 2000, p362-73 Journal Article, 2000 URL

E. Carton, M. T. Caldwell, G. McDonald, D. Rama, W. A. Tanner and J. V. Reynolds, Specialized intestinal metaplasia in patients with gastro-oesophageal reflux disease, The British journal of surgery, 87, (1), 2000, p116-21 Journal Article, 2000 URL

S. Kanwar, A. C. Windsor, F. Welsh, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Lack of correlation between failure of gut barrier function and septic complications after major upper gastrointestinal surgery, Annals of surgery, 231, (1), 2000, p88-95 Journal Article, 2000 URL

S. Kanwar, A. Windsor and J. V. Reynolds, Early enteral nutrition in acute pancreatitis, Nutrition (Burbank, Los Angeles County, Calif), 15, (11-Dec), 1999, p951-2 Journal Article, 1999 URL

F. K. Welsh, C. W. Ramsden, K. MacLennan, M. B. Sheridan, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Increased intestinal permeability and altered mucosal immunity in cholestatic jaundice, Annals of surgery, 227, (2), 1998, p205-12 Journal Article, 1998 URL

F. K. Welsh, S. M. Farmery, K. MacLennan, M. B. Sheridan, G. R. Barclay, P. J. Guillou and J. V. Reynolds, Gut barrier function in malnourished patients, Gut, 42, (3), 1998, p396-401 Journal Article, 1998 URL

A. C. Windsor, S. Kanwar, A. G. Li, E. Barnes, J. A. Guthrie, J. I. Spark, F. Welsh, P. J. Guillou and J. V. Reynolds, Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis, Gut, 42, (3), 1998, p431-5 Journal Article, 1998 URL

A. Klava, A. C. Windsor, S. M. Farmery, L. F. Woodhouse, J. V. Reynolds, C. W. Ramsden, A. W. Boylston and P. J. Guillou, Interleukin-10. A role in the development of postoperative immunosuppression, Archives of surgery (Chicago, Ill, 132, (4), 1997, p425-9 Journal Article, 1997 URL

J. Harbison, J. V. Reynolds, K. Sheahan, R. G. Gibney and J. M. Hyland, Evidence for the polyp-cancer sequence in gallbladder cancer, Irish medical journal, 90, (3), 1997, p98 Journal Article, 1997 URL

A. Blakeborough, R. G. McWilliams, U. Raja, P. J. Robinson, J. V. Reynolds and A. H. Chapman, Pseudolipoma of inverted Meckel's diverticulum: clinical, radiological and pathological correlation, European radiology, 7, (6), 1997, p900-4 Journal Article, 1997 URL

J. V. Reynolds, S. Kanwar, F. K. Welsh, A. C. Windsor, P. Murchan, G. R. Barclay and P. J. Guillou, 1997 Harry M. Vars Research Award. Does the route of feeding modify gut barrier function and clinical outcome in patients after major upper gastrointestinal surgery?, JPEN Journal of parenteral and enteral nutrition, 21, (4), 1997, p196-201 Journal Article, 1997 URL

A. Klava, A. Windsor, A. W. Boylston, J. V. Reynolds, C. W. Ramsden and P. J. Guillou, Monocyte activation after open and laparoscopic surgery, The British journal of surgery, 84, (8), 1997, p1152-6 Journal Article, 1997 URL

F. K. Welsh, S. M. Farmery, C. Ramsden, P. J. Guillou and J. V. Reynolds, Reversible impairment in monocyte major histocompatibility complex class II expression in malnourished surgical patients, JPEN Journal of parenteral and enteral nutrition, 20, (5), 1996, p344-8 Journal Article, 1996 URL

J. V. Reynolds, C. O'Farrelly, C. Feighery, P. Murchan, N. Leonard, G. Fulton, C. O'Morain, F. B. Keane and W. A. Tanner, Impaired gut barrier function in malnourished patients, The British journal of surgery, 83, (9), 1996, p1288-91 Journal Article, 1996 URL

J. V. Reynolds, W. P. Joyce, J. Dolan, K. Sheahan and J. M. Hyland, Pathological evidence in support of total mesorectal excision in the management of rectal cancer, The British journal of surgery, 83, (8), 1996, p1112-5 Journal Article, 1996 URL

J. V. Reynolds, P. Murchan, N. Leonard, P. Clarke, F. B. Keane and W. A. Tanner, Gut barrier failure in experimental obstructive jaundice, The Journal of surgical research, 62, (1), 1996, p11-Jun Journal Article, 1996 URL

J. V. Reynolds, Gut barrier function in the surgical patient, The British journal of surgery, 83, (12), 1996, p1668-9 Journal Article, 1996 URL

J. V. Reynolds, P. Murchan, H. P. Redmond, R. W. Watson, N. Leonard, A. Hill, P. Clarke, P. Marks, F. B. Keane and W. A. Tanner, Failure of macrophage activation in experimental obstructive jaundice: association with bacterial translocation, The British journal of surgery, 82, (4), 1995, p534-8 Journal Article, 1995 URL

A. C. Windsor, A. Klava, S. S. Somers, P. J. Guillou and J. V. Reynolds, Manipulation of local and systemic host defence in the prevention of perioperative sepsis, The British journal of surgery, 82, (11), 1995, p1460-7 Journal Article, 1995 URL

J. V. Reynolds, K. Walsh, J. Ruigrok and J. M. Hyland, Randomised comparison of silicone versus Teflon cannulas for peripheral intravenous nutrition, Annals of the Royal College of Surgeons of England, 77, (6), 1995, p447-9 Journal Article, 1995 URL

J. V. Reynolds and W. E. Enker, A simple, safe technique for stapled reconstruction after right hemicolectomy, Journal of the American College of Surgeons, 181, (2), 1995, p178-81 Journal Article, 1995 URL

A. C. Windsor, S. S. Somers, A. Crellin, S. Hassan, R. Macadam, S. A. Sadek, P. J. Guillou and J. V. Reynolds, Paradoxical clinical deterioration despite near-complete pathological response to neoadjuvant chemotherapy for locally advanced gastro-oesophageal adenocarcinoma, Surgical oncology, 4, (5), 1995, p277-9 Journal Article, 1995 URL

J. V. Reynolds, P. Murchan, N. Leonard, D. B. Gough, P. Clarke, F. B. Keane and W. A. Tanner, High-dose interleukin 2 promotes bacterial translocation from the gut, British journal of cancer, 72, (3), 1995, p634-6 Journal Article, 1995 URL

G. J. Fulton, M. K. O'Donohoe, J. V. Reynolds, F. B. Keane and W. A. Tanner, Wedge resection alone or combined with segmental phenolization for the treatment of ingrowing toenail, The British journal of surgery, 81, (7), 1994, p1074-5 Journal Article, 1994 URL

J. V. Reynolds, P. Mercer, E. W. McDermott, S. Cross, M. Stokes, D. Murphy and N. J. O'Higgins, Audit of complete axillary dissection in early breast cancer, European journal of cancer (Oxford, England, 30A, (2), 1994, p148-9 Journal Article, 1994 URL

J. V. Reynolds, J. P. Sweeney, N. Nolan, A. Korebrits, M. J. Duffy, E. W. McDermott and N. J. O'Higgins, Management of ductal carcinoma in situ of the breast, Irish journal of medical science, 162, (2), 1993, p45-8 Journal Article, 1993 URL

J. V. Reynolds, S. S. Somers and P. J. Guillou, Inhibition of interleukin-2 dependent immune responses by serum from patients with advanced gastrointestinal cancer, Surgical oncology, 2, (4), 1993, p227-34 Journal Article, 1993 URL

S. S. Somers, J. V. Reynolds and P. J. Guillou, Multifocal neurotoxicity during interleukin-2 therapy for malignant melanoma, Clinical oncology (Royal College of Radiologists (Great Britain)), 4, (2), 1992, p135-6 Journal Article, 1992 URL

J. V. Reynolds, H. P. Redmond, N. Ueno, C. Steigman, M. M. Ziegler, J. M. Daly and R. B. Johnston, Jr., Impairment of macrophage activation and granuloma formation by protein deprivation in mice, Cellular immunology, 139, (2), 1992, p493-504 Journal Article, 1992 URL

H. P. Redmond, P. Leon, M. D. Lieberman, K. Hofmann, J. Shou, J. V. Reynolds, J. Goldfine, R. B. Johnston, Jr. and J. M. Daly, Impaired macrophage function in severe protein-energy malnutrition, Archives of surgery (Chicago, Ill, 126, (2), 1991, p192-6 Journal Article, 1991 URL

R. K. Sigal, M. D. Lieberman, J. V. Reynolds, J. Shou, M. M. Ziegler and J. M. Daly, Low-dose interferon gamma renders neuroblastoma more susceptible to interleukin-2 immunotherapy, Journal of pediatric surgery, 26, (4), 1991, p389-95; discussion 395-6 Journal Article, 1991 URL

Cambieri A, Muzii M, Catananti C, Candia L, [Hospitals and immigration: analysis of a case series]., Recenti progressi in medicina, 81, (7-8), 1991, p461-73 Journal Article, 1991

J. V. Reynolds and J. M. Galloway, Primary aortoduodenal fistula: a case report and review of the literature, Irish journal of medical science, 160, (12), 1991, p381-4 Journal Article, 1991 URL

R. K. Sigal, M. D. Lieberman, J. V. Reynolds, N. Williams, M. M. Ziegler and J. M. Daly, Tumor immunization. Improved results after vaccine modified with recombinant interferon gamma, Archives of surgery (Chicago, Ill, 125, (3), 1990, p308-12 Journal Article, 1990 URL

J. V. Reynolds, J. A. Shou, R. Sigal, M. Ziegler and J. M. Daly, The influence of protein malnutrition on T cell, natural killer cell, and lymphokine-activated killer cell function, and on biological responsiveness to high-dose interleukin-2, Cellular immunology, 128, (2), 1990, p569-77 Journal Article, 1990 URL

J. V. Reynolds, J. M. Daly, J. Shou, R. Sigal, M. M. Ziegler and A. Naji, Immunologic effects of arginine supplementation in tumor-bearing and non-tumor-bearing hosts, Annals of surgery, 211, (2), 1990, p202-10 Journal Article, 1990 URL

S. H. Choi, J. V. Reynolds and M. M. Ziegler, Systematic analysis of the immunoregulation of murine neuroblastoma, Journal of pediatric surgery, 24, (1), 1989, p15-9; Discussion 19-20 Journal Article, 1989 URL

J. V. Reynolds, J. Shou, H. Choi, R. Sigal, M. M. Ziegler and J. M. Daly, The influence of natural killer cells in neuroblastoma, Archives of surgery (Chicago, Ill, 124, (2), 1989, p235-9 Journal Article, 1989 URL

J. V. Reynolds, A. K. Thom, S. M. Zhang, M. M. Ziegler, A. Naji and J. M. Daly, Arginine, protein malnutrition, and cancer, The Journal of surgical research, 45, (6), 1988, p513-22 Journal Article, 1988 URL

J. V. Reynolds, J. M. Daly, S. Zhang, E. Evantash, J. Shou, R. Sigal and M. M. Ziegler, Immunomodulatory mechanisms of arginine, Surgery, 104, (2), 1988, p142-51 Journal Article, 1988 URL

J. V. Reynolds, W. F. Kealy and G. C. O'Sullivan, Multiple pulmonary leiomyomatous hamartomas, Irish medical journal, 77, (4), 1984, p106-7 Journal Article, 1984 URL

Research Expertise

Description

Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.

Keywords

Anti-oxidants in inflammatory disease; Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus; Liver and gut immune function in patients undergoing complex major surgery; Molecular predictors of response and resistance to chemotherapy and radiation therapy; Transcription factors in inflammation and neoplasia of the oesophagus; Upper gastrointestinal physiology

Recognition

Representations

Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.

Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).

Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.

Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics