John O'Leary
Professor Consultant, Histopathology
Professor Consultant, Molecular Medicine Ireland

Publications and Further Research Outputs

Peer-Reviewed Publications

Aherne, S.T., Smyth, P., Freeley, M., Smith, L., Spillane, C., O'Leary, J., Sheils, O., Altered expression of MIR-222 and MIR-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression, International Journal of Molecular Medicine, 38, (2), 2016, p433-445 Journal Article, 2016 DOI

O'Connor M, O'Leary E, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin C.M, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary J.J, Sharp L, Trends in, and predictors of, anxiety and specific worries following colposcopy: A 12-month longitudinal study, Psycho-Oncology, 25, (5), 2016, p597 - 604 Journal Article, 2016 URL DOI

Emma R Dorris, Gordon Blackshields, Gary Sommerville, Mohsen Alhashemi, Andrew Dias, Victoria McEneaney, Paul Smyth, John J O'Leary, Orla Sheils, Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines, Cancer biology & therapy, 17, (5), 2016, p526 - 542 Journal Article, 2016 DOI

McEvoy, L.M., O'Toole, S.A., Spillane, C.D., Martin, C.M., Gallagher, M.F., Stordal, B., Blackshields, G., Sheils, O., O'Leary, J.J., Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer, BMC Cancer, 15, (1), 2015, p547- Journal Article, 2015 DOI TARA - Full Text

O'Connor M, Waller J, Gallagher P, Martin C.M, O'Leary J.J, D'Arcy , Prendiville W, Flannelly G, Sharp L, Understanding Women's Differing Experiences of Distress after Colposcopy: A Qualitative Interview Study, Women's Health Issues, 25, (5), 2015, p528 - 534 Journal Article, 2015 URL DOI

Busschots,Steven S., O'Toole,Sharon A. S.A., O'Leary,John James J.J., Stordal,Britta K. B.K., Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines, MethodsX, 2, 2015, p8-13 Journal Article, 2015 TARA - Full Text DOI

Gallagher, M.F., Salley, Y., Spillane, C.D., Ffrench, B., Baruni, S.E., Blacksheilds, G., Smyth, P., Martin, C., Sheils, O., Watson, W., O'Leary, J.J., Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones, Journal of Clinical Pathology, 68, (9), 2015, p692-702 Journal Article, 2015 DOI

Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA, Endosomal gene expression: a new indicator for prostate cancer patient prognosis?, Oncotarget, 6, (35), 2015, p37919-29 Journal Article, 2015 DOI TARA - Full Text

Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease, Cancer Letters, 356, ((2ptB)), 2015, p628-636- Journal Article, 2015 DOI

Holl K, Nowakowski A.M, Powell N, McCluggage W.G, Pirog E.C, Collas De Souza S, Tjalma W.A, Rosenlund M, Fiander A, Castro Sánchez M, Damaskou V, Joura E.A, Kirschner B, Koiss R, O'Leary J, Quint W, Reich O, Torné A, Wells M, Rob L, Kolomiets L, Molijn A, Savicheva A, Shipitsyna E, Rosillon D, Jenkins D, Human papillomavirus prevalence and type-distribution in cervical glandular neoplasias: Results from a European multinational epidemiological study, International Journal of Cancer, 137, (12), 2015, p2858 - 2868 Journal Article, 2015 URL DOI

Cooke, N.M., Spillane, C.D., Sheils, O., O'Leary, J., Kenny, D., Aspirin and P2Y12 inhibition attenuate platelet-induced ovarian cancer cell invasion, BMC Cancer, 15, (1), 2015, p627- Journal Article, 2015 TARA - Full Text DOI

Langhe R, Norris L, Saadeh FA, Blackshields G, Varley R, Harrison A, Gleeson N, Spillane C, Martin C, O'Donnell DM, D'Arcy T, O'Leary J, O'Toole S, A novel serum microRNA panel to discriminate benign from malignant ovarian disease., Cancer letters, 356, (2 Pt B), 2015, p628-36 Journal Article, 2015 DOI

O'Connor M, Costello L, Murphy J, Prendiville W, Martin CM, O'Leary JJ, Sharp L, Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology., The journal of family planning and reproductive health care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists, 41, (2), 2015, p134-141 Journal Article, 2015 DOI

Busschots S, O'Toole S, O'Leary JJ, Stordal B. , Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells, Experimental Cell Research, 2014, p1 - 14 Journal Article, 2014 DOI TARA - Full Text

Keegan Helen, Pilkington Loretto, McInerney Jamie, Jeney Csaba, Benczik Márta, Cleary Sinead, von Bunau Gunther, Turner Michael, D'Arcy Tom, O' Toole Sharon, Borbála Pal-Szenthe, Borbála Kaltenecker, Johanna Mózes, Anettc Kovács, Agnes Solt, Bolger Noel, O'Leary John, Martin Cara., Human papillomavirus detection and genotyping, by HC2, Full-Spectrum HPV and Molecular Beacon Real-Time HPV assay in an Irish colposcopy clinic, Journal of Virological Methods, 2014 Journal Article, 2014 TARA - Full Text

Kelly LA, Seidlova-Wuttke D, Wuttke W, O'Leary JJ, Norris LA, Estrogen receptor alpha augments changes in hemostatic gene expression in HepG2 cells treated with estradiol and phytoestrogens. , Phytomedicine , 21, (2), 2014, p155 - 158 Journal Article, 2014 URL

Keegan H, Pilkington L, McInerney J, Jeney C, Benczik M, Cleary S, von Bunau G, Turner M, D'Arcy T, O' Toole S, Pal-Szenthe B, Kaltenecker B, Mózes J, Kovács A, Solt A, Bolger N, O'Leary J, Martin C, Human papillomavirus detection and genotyping, by HC2, full-spectrum HPV and molecular beacon real-time HPV assay in an Irish colposcopy clinic., Journal of virological methods, 201, 2014, p93-100 Journal Article, 2014

Glynn M, Kirby D, Nwankire C, Kinahan D, Spillane C, Shiels O, O'Leary J, Ducrée J, Staging the clinical status from blood of cancer patients by chip-based cell enumeration following targetted removal of normal cells, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, 2014, 2014, pp461 - 463 Conference Paper, 2014 URL

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ, The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer., PloS one, 9, (6), 2014, pe100816 Journal Article, 2014 DOI TARA - Full Text

Lawlor, D. Martin, P. Busschots, S. Thery, J. O'Leary, J.J. Hennessy, B.T. Stordal, B., PARP inhibitors as p-glyoprotein substrates, Journal of Pharmaceutical Sciences, 103, (6), 2014, p1913 - 1920 Journal Article, 2014 URL DOI

O'Brien CP, Taylor SE, O'Leary JJ, Finn SP, Molecular testing in oncology: Problems, pitfalls and progress., Lung cancer (Amsterdam, Netherlands), 2014 Journal Article, 2014 TARA - Full Text DOI

O'Connor M, Costello L, Murphy J, Prendiville W, Martin C.M, O'Leary J.J, Sharp L, 'I don't care whether it's HPV or ABC, i just want to know if i have cancer.' Factors influencing women's emotional responses to undergoing human papillomavirus testing in routine management in cervical screening: A qualitative study, BJOG: An International Journal of Obstetrics and Gynaecology, 121, (11), 2014, p1421 - 1429 Journal Article, 2014 URL DOI

Rashid N, Nawaz H, Poon KW, Bonnier F, Bakhiet S, Martin C, O'Leary JJ, Byrne HJ, Lyng FM, Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue., Experimental and molecular pathology, 97, (3), 2014, p554-64 Journal Article, 2014

Doherty B, Lawlor D, Gillet JP, Gottesman M, O'Leary JJ, Stordal B, Collateral Sensitivity to Cisplatin in KB-8-5-11 Drug-resistant Cancer Cells., Anticancer research, 34, (1), 2014, p503-7 Journal Article, 2014 Other TARA - Full Text

O'Connor, M. Murphy, J. Martin, C. O'Leary, J. Sharp, L., Motivators for women to attend cervical screening: The influential role of GPs, Family Practice, 31, (4), 2014, p475-482 Journal Article, 2014 URL DOI TARA - Full Text

O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP, Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns., Molecular diagnosis & therapy, 18, (1), 2014, p1-4 Journal Article, 2014 DOI

Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ, An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines., BMC genomics, 15, 2014, p711 Journal Article, 2014 TARA - Full Text DOI

Sadlier C, Rowley D, Morley D, Surah S, O'Dea S, Delamere S, O'Leary J, Smyth P, Clarke S, Sheils O, Bergin C, Prevalence of human papillomavirus in men who have sex with men in the era of an effective vaccine; a call to act., HIV medicine, 15, (8), 2014, p499-504 Journal Article, 2014 DOI TARA - Full Text

Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F., Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population., International Journal of Sexually Transmitted Diseases and AIDS, 2014 Journal Article, 2014

McRae, J. Martin, C. O'Leary, J. Sharp, L., "If you can't treat HPV, why test for it?" Women's attitudes to the changing face of cervical cancer prevention: A focus group study, BMC Women's Health, 14, (1), 2014, p64- Journal Article, 2014 TARA - Full Text URL DOI

Ffrench B, Gasch C, O'Leary JJ, Gallagher MF, Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention., Molecular cancer, 13, 2014, p262 Journal Article, 2014 DOI TARA - Full Text

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ., The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer., PLoS One. , 9, (6), 2014, pe100816- Journal Article, 2014 DOI TARA - Full Text

Bonnier,F, Traynor, D, Kearney, P, Clarke,C, Peter Knief, P Martin, C, O'Leary,J, Byrne HJ and Lyng, F, Processing ThinPrep Cervical Cytological Samples for Raman Spectroscopic Analysis., Analytical Methods, 6, (19), 2014, p7831 - 7841 Journal Article, 2014

Brosnan JF, Sheppard BL, Kelly LA, O'Leary JJ, Norris LA, Norethisterone acetate alters coagulation gene expression in vitro in human cell culture., Thrombosis research, 131, (1), 2013, p72 - 77 Journal Article, 2013 DOI

Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, Fennell DA, Richard D, O'Leary JJ, O'Byrne KJ., Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature., PloS one, 8, (1), 2013, pe54193 Journal Article, 2013 TARA - Full Text DOI URL

Tjalma WA, Fiander A, Reich O, Powell N, Nowakowski AM, Kirschner B, Koiss R, O'Leary J, Joura EA, Rosenlund M, Colau B, Schledermann D, Kukk K, Damaskou V, Repanti M, Vladareanu R, Kolomiets L, Savicheva A, Shipitsyna E, Ordi J, Molijn A, Quint W, Raillard A, Rosillon D, De Souza SC, Jenkins D, Holl K, Differences in human papillomavirus type distribution in high-grade cervical intraepithelial neoplasia and invasive cervical cancer in Europe., International journal of cancer. Journal international du cancer, 132, (4), 2013, p854-67 Journal Article, 2013

White C, Keegan H, Pilkington L, Ruttle C, Kerr P, Sharp L, O'Toole S, Turner M, Prendiville W, D'Arcy T, Fitzpatrick M, Lenehan P, Flannelly G, O'Leary JJ, Martin CM, Evaluation of the clinical performance of the cobas 4800 HPV test in patients referred for colposcopy., Journal of clinical microbiology, 51, (10), 2013, p3415-7 Journal Article, 2013 DOI TARA - Full Text

Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103 Journal Article, 2013 DOI TARA - Full Text

Abu Saadeh, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N, Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis risk., Thrombosis Research, 132, 2013, p627 - 634 Journal Article, 2013 DOI

Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, Fitzgerald KA, Daly S, O'Leary JJ, O'Neill LA, TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia., Journal of immunology (Baltimore, Md. : 1950), 188, (11), 2012 Journal Article, 2012 TARA - Full Text DOI

Flavin R, Finn SP, Choueiri TK, Ingoldsby H, Ring M, Barrett C, Rogers M, Smyth P, O'Regan E, Gaffney E, O'Leary JJ, Loda M, Signoretti S, Sheils O, RET protein expression in papillary renal cell carcinoma., Urologic oncology, 30, (6), 2012, p900-5 Journal Article, 2012

Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A, Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer., The Journal of pathology, 226, (5), 2012, p746-55 Journal Article, 2012

Logan C, Habington A, Lennon G, Grogan J, Byrne M, O'Leary J, O'Sullivan N, Genetic relatedness of Pseudomonas aeruginosa isolates among a paediatric cystic fibrosis patient cohort in Ireland., Journal of medical microbiology, 61, (Pt 1), 2012, p64-70 Journal Article, 2012

Gallagher MF, Heffron CC, Laios A, O'Toole SA, Ffrench B, Smyth PC, Flavin RJ, Elbaruni SA, Spillane CD, Martin CM, Sheils OM, O'Leary JJ, Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples., Journal of ovarian research, 5, (1), 2012, p2 Journal Article, 2012

O'Flaherty JD, Gray S, Richard D, Fennell D, O'Leary JJ, Blackhall FH, O'Byrne KJ, Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer., Lung cancer (Amsterdam, Netherlands), 76, (1), 2012, p19-25 Journal Article, 2012 DOI

Gulliksen A, Keegan H, Martin C, O'Leary J, Solli LA, Falang IM, Grønn P, Karlgård A, Mielnik MM, Johansen IR, Tofteberg TR, Baier T, Gransee R, Drese K, Hansen-Hagge T, Riegger L, Koltay P, Zengerle R, Karlsen F, Ausen D, Furuberg L, Towards a "Sample-In, Answer-Out" Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System., Journal of oncology, 2012, 2012, p905024 Journal Article, 2012

O'Flaherty JD, Barr M, Fennell D, Richard D, Reynolds J, O'Leary J, O'Byrne K, The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7, (12), 2012, p1880-90 Journal Article, 2012 DOI

McSherry LA, Dombrowski SU, Francis JJ, Murphy J, Martin CM, O'Leary JJ, Sharp L, Group A, 'It's a can of worms': understanding primary care practitioners' behaviours in relation to HPV using the theoretical domains framework., Implementation science : IS, 7, (1), 2012, p73 Journal Article, 2012

Murphy MA, O'Leary JJ, Cahill DJ, Assessment of the humoral immune response to cancer., Journal of proteomics, 75, (15), 2012, p4573-9 Journal Article, 2012

Dorris ER, Smyth P, O'Leary JJ, Sheils O, MIR141 Expression Differentiates Hashimoto Thyroiditis from PTC and Benign Thyrocytes in Irish Archival Thyroid Tissues., Frontiers in endocrinology, 3, 2012, p102 Journal Article, 2012

Murphy MA, O'Connell DJ, O'Kane SL, O'Brien JK, O'Toole S, Martin C, Sheils O, O'Leary JJ, Cahill DJ, Epitope presentation is an important determinant of the utility of antigens identified from protein arrays in the development of autoantibody diagnostic assays, Journal of Proteomics, 75, (15), 2012, p4668 - 4675 Journal Article, 2012 TARA - Full Text

Oon SF, Watson RW, O'Leary JJ, Fitzpatrick JM, Epstein criteria for insignificant prostate cancer., BJU international, 2011 Journal Article, 2011 DOI

Yusof A, Keegan H, Spillane CD, Sheils OM, Martin CM, O'Leary JJ, Zengerle R, Koltay P, Inkjet-like printing of single-cells., Lab on a chip, 11, (14), 2011, p2447-54 Journal Article, 2011

O'Hurley G, Perry AS, O'Grady A, Loftus B, Smyth P, O'Leary JJ, Sheils O, Fitzpatrick JM, Hewitt SM, Lawler M, Kay EW, The role of secreted frizzled-related protein 2 expression in prostate cancer., Histopathology, 59, (6), 2011, p1240-1248 Journal Article, 2011 DOI

Grogan JA, Logan C, O'Leary J, Rush R, O'Sullivan N, Real-time PCR-based detection of Bordetella pertussis and Bordetella parapertussis in an Irish paediatric population., Journal of medical microbiology, 60, (Pt 6), 2011, p722-9 Journal Article, 2011

Cantwell-Dorris ER, O'Leary JJ, Sheils OM, BRAFV600E: implications for carcinogenesis and molecular therapy., Molecular cancer therapeutics, 10, (3), 2011, p385-94 Journal Article, 2011

Ostrowska KM, Garcia A, Meade AD, Malkin A, Okewumi I, O'Leary JJ, Martin C, Byrne HJ, Lyng FM, Correlation of p16(INK4A) expression and HPV copy number with cellular FTIR spectroscopic signatures of cervical cancer cells., The Analyst, 136, (7), 2011, p1365-73 Journal Article, 2011 DOI TARA - Full Text

Astbury K, McEvoy L, Brian H, Spillane C, Sheils O, Martin C, O'Leary JJ, MYBL2 (B-MYB) in cervical cancer: putative biomarker., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 21, (2), 2011, p206-12 Journal Article, 2011 DOI

Martin CM, O'Leary JJ, Histology of cervical intraepithelial neoplasia and the role of biomarkers., Best practice & research. Clinical obstetrics & gynaecology, 25, (5), 2011, p605-15 Journal Article, 2011

Karl Egan., Darragh Crowley., Paul Smyth, Sharon O'Toole, Cathy Spillane, Cara Martin, Michael Gallagher, Aoife Canney, Lucy Norris, Niamh Conlon, Lynda McEvoy2, Brendan Ffrench2, Britta Stordal, Helen Keegan, Stephen Finn, Victoria McEneaney, Alex Laios, Jens Ducre, Eimear Dunne, Leila Smith, Michael Berndt, Orla Sheils, Dermot Kenny, John O'Leary, Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells, PLoS ONE, 6, (10, e26125), 2011 Journal Article, 2011 TARA - Full Text

Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J, Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells., PloS one, 6, (10), 2011, pe26125 Journal Article, 2011

Ostrowska KM, Malkin A, Meade A, O'Leary J, Martin C, Spillane C, Byrne HJ, Lyng FM., Investigation of the influence of high-risk human papillomavirus on the biochemical composition of cervical cancer cells using vibrational spectroscopy., Analyst., (Oct 21), 2010 Journal Article, 2010 DOI

Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA., Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21, Nature Immunology, 11, (2), 2010, p141-147 Journal Article, 2010 DOI

Kelly JG, Cheung KT, Martin C, O'Leary JJ, Prendiville W, Martin-Hirsch PL, Martin FL, A spectral phenotype of oncogenic human papillomavirus-infected exfoliative cervical cytology distinguishes women based on age., Clinica chimica acta; international journal of clinical chemistry, 411, (15-16), 2010, p1027-1033 Journal Article, 2010 DOI

Kelly LA, O'Leary JJ, Seidlova-Wuttke D, Wuttke W, Norris LA, Genistein alters coagulation gene expression in ovariectomised rats treated with phytoestrogens, Thrombosis and Haemostasis, 104, (6), 2010, p1083-1289 Journal Article, 2010 TARA - Full Text

Mocanu E, Shattock R, Barton D, Rogers M, Conroy R, Sheils O, Collins C, Martin C, Harrison R, O'Leary J, All azoospermic males should be screened for cystic fibrosis mutations before intracytoplasmic sperm injection., Fertility and sterility, 2010 Journal Article, 2010 DOI

O'Hurley G, O'Grady A, Smyth P, Byrne J, O'Leary JJ, Sheils O, Watson RW, Kay EW, Evaluation of Zinc-alpha-2-Glycoprotein and Proteasome Subunit beta-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology., Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, 2010 Journal Article, 2010 DOI

Baier T, Hansen-Hagge TE, Gransee R, Crombé A, Schmahl S, Paulus C, Drese KS, Keegan H, Martin C, O'Leary JJ, Furuberg L, Solli L, Grønn P, Falang IM, Karlgård A, Gulliksen A, Karlsen F, Hands-free sample preparation platform for nucleic acid analysis., Lab on a chip, 9, (23), 2009, p3399-405 Journal Article, 2009 TARA - Full Text DOI

Flavin R, Jackl G, Finn S, Smyth P, Ring M, O'Regan E, Cahill S, Unger K, Denning K, Jinghuan Li Aherne S, Tallini G, Gaffney E, O'Leary JJ, Zitzelsberger H, Sheils O, RET/PTC rearrangement occurring in primary peritoneal carcinoma., International journal of surgical pathology, 17, (3), 2009, p187-97 Journal Article, 2009 DOI

Keegan, H., Mc Inerney, J., Pilkington, L., Grønn, P., Silva, I., Karlsen, F., Bolger, N., (...), Martin, C. , Comparison of HPV detection technologies: Hybrid capture 2, PreTect HPV-Proofer and analysis of HPV DNA viral load in HPV16, HPV18 and HPV33 E6/E7 mRNA positive specimens, Journal of Virological Methods , 155, (1), 2009, p61-66 Journal Article, 2009 DOI

Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, Snijders PJ, Smit EF, Sozzi G, Roz L, Risch A, Becker HD, Elborn JS, Magee ND, Montuenga LM, Pajares MJ, Lozano MD, O'Byrne KJ, Harrison DJ, Niklinski J, Cassidy A, EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration., The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 34, (6), 2009, p1477-86 Journal Article, 2009 DOI

Gallagher MF, Flavin RJ, Elbaruni SA, McInerney JK, Smyth PC, Salley YM, Vencken SF, O'Toole SA, Laios A, Lee MY, Denning K, Li J, Aherne ST, Lao KQ, Martin CM, Sheils OM, O'Leary JJ, Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients., Journal of ovarian research, 2, 2009, p19 Journal Article, 2009 TARA - Full Text DOI

Flavin R, Smyth P, Barrett C, Russell S, Wen H, Wei J, Laios A, O'Toole S, Ring M, Denning K, Li J, Aherne S, Sammarae D, Aziz NA, Alhadi A, Finn SP, Loda M, B S, Sheils O, O'Leary JJ, miR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 19, (4), 2009, p641-7 Journal Article, 2009 DOI

Flavin, R.J., Smyth, P.C., Laios, A., O'Toole, S.A., Barrett, C., Finn, S.P., Russell, S., (...), O'Leary, J.J. , Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma, Modern Pathology , 22, (2), 2009, p197-205 Journal Article, 2009 DOI

Hornig, M., Briese, T., Buie, T., Bauman, M.L., Lauwers, G., Siemetzki, U., Hummel, K., (...), Lipkin, W.I. , Lack of association between measles virus vaccine and autism with enteropathy: A case-control study , PLoS ONE, 3, (9), 2008, part. no. e3140 Journal Article, 2008 DOI

Laios, A., O'Toole, S.A., Flavin, R., Martin, C., Ring, M., Gleeson, N., D'Arcy, T., (...), O' Leary, J.J. , An integrative model for recurrence in ovarian cancer , Molecular Cancer, 7, 2008, part. no. 8 Journal Article, 2008 DOI

Aherne ST, Smyth PC, Flavin RJ, Russell SM, Denning KM, Li JH, Guenther SM, O'Leary JJ, Sheils OM., Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling., Molecular Cancer, 7, 2008, particle no, 89 Journal Article, 2008 DOI

Laios, A., O'Toole, S., Flavin, R., Martin, C., Kelly, L., Ring, M., Finn, S.P., (...), O'Leary, J. , Potential role of miR-9 and miR-223 in recurrent ovarian cancer , Molecular Cancer, 7, 2008, part. no. 35 Journal Article, 2008 TARA - Full Text DOI

Heffron, C.C.B.B., Gallagher, M.F., Guenther, S., Sherlock, J., Henfrey, R., Martin, C., Sheils, O., O'Leary, J.J. , Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model , Anticancer Research, 27, (3A), 2007, p1319-1324 Journal Article, 2007 URL

Crowley A, Martin C, Fitzpatrick P, Sheils O, O'Herlihy C, O'Leary JJ, Byrne BM, Free fetal DNA is not increased before 20 weeks in intrauterine growth, Prenat Diagn., 27, (2), 2007, p174 - 179 Journal Article, 2007 DOI

Murphy AJ, Hughes CA, Lannigan G, Sheils O, O'Leary J, Loftus B, Heterogeneous expression of alpha-methylacyl-CoA racemase in prostatic cancer correlates with Gleason score, Histopathology, 50, (2), 2007, p243 - 251 Journal Article, 2007 DOI

Logan, C., O'Leary, J.J., O'Sullivan, N. , Real-time reverse transcription PCR detection of norovirus, sapovirus and astrovirus as causative agents of acute viral gastroenteritis , Journal of Virological Methods, 146, (1-2), 2007, p36-44 Journal Article, 2007 DOI

O'Toole SA, Sheppard BL, Laios A, O'Leary JJ, McGuinness EP, D'Arcy T,Bonnar J, Potential predictors of chemotherapy response in ovarian cancer--how do we define chemosensitivity?, Gynecol Oncol., 104, (2), 2007, p345 - 351 Journal Article, 2007 DOI

Martin CM, Kehoe L, Spillane CO, O'Leary JJ., Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers., Molecular Diagnosis and Therapy , 11, (5), 2007, p277-90 Journal Article, 2007

Furuberg, L., Mielnik, M., Johansen, I.-R., Voitel, J., Gulliksen, A., Solli, L., Karlsen, F., (...), Koltay, P. , The micro active project: Automatic detection of disease-related molecular cell activity , Proceedings of SPIE - The International Society for Optical Engineering, 6589, 2007, part. no. 65891B Journal Article, 2007 DOI

Finn SP, Smyth P, Cahill S, Streck C, O'regan EM, Flavin R, Sherlock J,Howells D, Henfrey R, Cullen M, Toner M, Timon C, O'leary JJ, Sheils OM, Expression microarray analysis of papillary thyroid carcinoma and benign thyroid tissue: emphasis on the follicular variant and potential markers of malignancy, Virchows Arch, 450, (3), 2007, p249 - 260 Journal Article, 2007 DOI

Murphy AJ, Hughes CA, Barrett C, Magee H, Loftus B, O'Leary JJ, Sheils O, Low Level TOP2A Amplification in Prostate Cancer is associated with HER2 Duplication, Androgen Resistance and Decreased Survival, Cancer Research , 67, (6), 2007, p2893 - 2898 Journal Article, 2007 DOI

Bolger, N., Heffron, C., Regan, I., Sweeney, M., Kinsella, S., McKeown, M., Creighton, G., (...), O'Leary, J. , Cervical cytology: Implementation and evaluation of a new automated interactive image analysis system , Acta Cytologica, 50 - (5), 2006, p483-491 Journal Article, 2006

Tumour markers in cervical cancer in, editor(s)Jordan JA, Singer A , The Cervix, Blackwell Publishing, 2006, pp399 - 413, [O'Leary JJ, Astbury K, Prendiville W] Book Chapter, 2006

Astbury, K., Martin, C.M., Ring, M., Pilkington, L., Bolger, N., Sheils, O.M., O'Leary, J.J. , Future molecular aspects of cervical cytology , Current Diagnostic Pathology, 12, (2), 2006, p104-113 Journal Article, 2006 DOI

Logan C, O'Leary JJ, O'Sullivan N, Real-time reverse transcription-PCR for detection of rotavirus and adenovirus as causative agents of acute viral gastroenteritis in children, J Clin Microbiol., 44, (9), 2006, p3189 - 3195 Journal Article, 2006 DOI

Bolger N, Heffron C, Regan I, Sweeney M, Kinsella S, McKeown M, Creighton G,Russell J, O'Leary J, Implementation and evaluation of a new automated interactive image analysis system, Acta Cytol., 50, (5), 2006, p483 - 491 Journal Article, 2006

O'Regan EM, Timon C, Sheils O, Codd M, O'Leary JJ, Toner M, Squamous cell carcinoma of the head and neck in young Irish adults, British Journal of Oral and Maxillofacial Surgery , 44, (3), 2006, p203 - 206 Journal Article, 2006 DOI

Martin CM, Astbury K, O'Leary JJ, Molecular profiling of cervical neoplasia, Expert Review of Molecular Diagnostics , 6, (2), 2006, p217 - 229 Journal Article, 2006 DOI

Hughes C, Murphy A, Martin C, Fox E, Ring M, Sheils O, Loftus B, O'Leary J, Topoisomerase II-alpha expression increases with increasing Gleason score and with hormone insensitivity in prostate carcinoma, Journal of Clinical Pathology, 59, (7), 2006, p721 - 724 Journal Article, 2006 DOI

Pathology 2026: The future of laboratory medicine and academic pathology in, editor(s)John Wiley & Sons , Understanding disease, John Wiley & Sons, 2006, pp217 - 231, [O'Leary JJ] Book Chapter, 2006

Leahy M, Farah N, Bolger N, O'Leary JJ, Turner MJ, Should cervical smears be taken at a postnatal visit?, Irish Medical Journal, 99, (8), 2006, p244 - 245 Journal Article, 2006

O'Toole SA, Dunn E, Sheppard BL, Klocker H, Bektic J, Smyth P, Martin C, Sheils O, O'Leary JJ, Genome-wide analysis of deoxyribonucleic acid in endometrial cancer using comparative genomic hybridization microarrays, International Journal of Gynecological Cancer , 16, (2), 2006, p834 - 842 Journal Article, 2006 DOI

In-cell PCR in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp505 - 513, [O'Leary, J.J., Martin, C.M., Sheils, O.] Book Chapter, 2005

Murphy, N., Ring, M., Heffron, C.C.B.B., Martin, C.M., McGuinness, E., Sheils, O., O'Leary, J.J., Quantitation of CDC6 and MCM5 mRNA in cervical intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix, Modern Pathology , 18, (6), 2005, p844-849 Journal Article, 2005 DOI

O'Toole SA, Dunn E, Sheppard BL, Sheils O, O'Leary JJ, Wuttke W,, Oestrogen regulated gene expression in normal and malignant endometrial tissue, Maturitas, 51, (2), 2005, p187 - 198 Journal Article, 2005 DOI

DNA Sequencing in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp531 - 539, [Martin, C.M., Picton, S.J. Sheils, O., O'Leary, J.J.] Book Chapter, 2005

O'Toole SA, Sheppard BL, Sheils O, O'Leary JJ, Spengler B, Christoffel V, Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays, Planta Medica, 71, (5), 2005, p435 - 439 Journal Article, 2005 DOI

Murphy N, Ring M, Heffron CC, King B, Killalea AG, Hughes C, Martin CM,McGuinness E, Sheils O, O'Leary JJ, p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive, Journal of Clinical Pathology, 58, (5), 2005, p525 - 534 Journal Article, 2005 DOI

Molecular markers in cervical dyskaryosis in, editor(s)Davies P.O.,Prendiville W , The Clinican's HPV handbook (vol 1), Parthenon Medical Publishing, 2005, pp73 - 88, [Murphy, N., Ring, M., Sheils, O., O'Leary, J.J.] Book Chapter, 2005

Mocanu EV, Adala S, O'Leary JJ, Womb with a view, Human Fertility (Camb)., 8, (1), 2005, p35 - 40 Journal Article, 2005 DOI

Laser capture microdissection in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp489 - 493, [Sheils, O., Smyth, P., O'Regan, E.M.,Finn, S., Flavin, R., O'Leary, J.J.] Book Chapter, 2005

High density SNP and cDNA array analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp515 - 521, [Sheils, O., Smyth, P., Sherlock, J., Martin, C.M., Finn, S., O'Regan, E.M., O'Leary, J.J.] Book Chapter, 2005

Smyth P, Finn S, Cahill S, O'Regan E, Flavin R, O'Leary JJ, Sheils O, ret/PTC and BRAF act as distinct molecular, time-dependant triggers in a sporadic Irish cohort of papillary thyroid carcinoma, International Journal of Surgical Pathology, 13, (1), 2005, p1 - 8 Journal Article, 2005 DOI

Hughes C, Murphy A, Martin C, Sheils O, O'Leary J, Molecular pathology of prostate cancer, Journal of Clinical Pathology, 58, (7), 2005, p673 - 684 Journal Article, 2005 DOI

CGH array analysis of human tissues in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp523 - 528, [O'Regan, E, Martin, C.M., Finn, S, Smyth, P., Flavin, R., O'Leary, J.J. Sheils, O.] Book Chapter, 2005

Real Time PCR gene analysis in, editor(s)Crocker, J. Burnett, D. , The Science of Laboratory Diagnosis, John Wiley & Sons, Ltd., 2005, pp495 - 504, [Martin, C.M., Sheils, O, O'Leary, J.J.] Book Chapter, 2005

N. Murphy, C. C. Heffron, B. King, U. G. Ganuguapati, M. Ring, E. McGuinness, O. Sheils and J. J. O'Leary, P16(INK4A) positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem, Virchows Archiv, 445, (6), 2004, p610-615 Journal Article, 2004 DOI

Bofin, A.M., Ytterhus, B., Martin, C., O'Leary, J.J., Hagmar, B.M., Detection and quantitation of HER-2 gene amplification and protein expression in breast carcinoma , American Journal of Clinical Pathology, 122, (1), 2004, p110-119 Journal Article, 2004 DOI

A. M. Cotter, C. M. Martin, J. O'Leary J and S. F. Daly, Increased fetal DNA in the maternal circulation in early pregnancy is associated with an increased risk of preeclampsia, American Journal of Obstetrics and Gynecology, 191, (2), 2004, p515-520 Journal Article, 2004 DOI

S. P. Finn, P. Smyth, E. O'Regan, S. Cahill, R. Flavin, J. O'Leary and O. Sheils, Array comparative genomic hybridisation analysis of gamma-irradiated human thyrocytes, Virchows Arch, 445, (4), 2004, p396-404 Journal Article, 2004 DOI

D. Kane, M. Gogarty, J. O'Leary, I. Silva, N. Bermingham, B. Bresnihan and O. Fitzgerald, Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate, Arthritis and Rheumatism, 50, (10), 2004, p3286-3295 Journal Article, 2004 DOI

O'Leary, J.J., Potential viral pathogenic mechanism for new variant inflammatory bowel disease [1] , 2003, - 248 Miscellaneous, 2003 DOI

Sheils, O., Finn, S., O'Leary, J., Nucleic acid microarrays: An overview, 9, (3), 2003, pPages 155-158 Journal Article, 2003 DOI

P. Smyth, S. Finn, J. O'Leary and O. Sheils, Real-time analysis of beta- and gamma-catenin mRNA expression in ret/PTC-1 activated and nonactivated thyroid tissues, Diagnostic Molecular Pathology, 12, (1), 2003, p44-49 Journal Article, 2003 DOI

B. M. Byrne, A. Crowley, F. Taulo, J. Anthony, J. J. O'Leary and C. O'Herlihy, Fetal DNA quantitation in peripheral blood is not useful as a marker of disease severity in women with preeclampsia, Hypertension in pregnancy, 22, (2), 2003, p157-64 Journal Article, 2003 DOI

N. Murphy, M. Ring, A. G. Killalea, V. Uhlmann, M. O'Donovan, F. Mulcahy, M. Turner, E. McGuinness, M. Griffin, C. Martin, O. Sheils and J. J. O'Leary, p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrep smears, Journal of Clinical Pathology, 56, (1), 2003, p56-63 Journal Article, 2003 DOI URL

Sheils, O.M., Finn, S., O'Leary, J.J., Quality-control issues for PCR-based assays in the molecular laboratory , 9, (3), 2003, p165-172 Journal Article, 2003 DOI

J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Analysis of fetal DNA in the maternal venous blood for abnormalities of chromosomes 13, 16, 18 and 21 in first-trimester spontaneous miscarriage, Journal of obstetrics and gynaecology, 23, (3), 2003, p228-232 Journal Article, 2003 URL DOI

S. P. Finn, P. Smyth, J. O'Leary, E. C. Sweeney and O. Sheils, Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma, Journal of Clinical Endocrinology and Metabolism, 88, (2), 2003, p938-941 Journal Article, 2003 DOI

Turner, M.J., Martin, C.M., O'Leary, J.J., Letter to the Editor [2] , 2003, - 118 Miscellaneous, 2003 DOI

M. J. Turner, C. M. Martin and J. J. O'Leary, Detection of fetal Rhesus D gene in whole blood of women booking for routine antenatal care, European journal of obstetrics, gynecology, and reproductive biology, 108, (1), 2003, p29-32 Journal Article, 2003 DOI URL

V. Uhlmann, C. M. Martin, O. Sheils, L. Pilkington, I. Silva, A. Killalea, S. B. Murch, J. Walker-Smith, M. Thomson, A. J. Wakefield and J. J. O'Leary, Potential viral pathogenic mechanism for new variant inflammatory bowel disease, Molecular pathology, 55, (2), 2002, p84-90 Journal Article, 2002 URL DOI

C. M. Martin, V. Uhlmann, A. Killalea, O. Sheils and J. J. O'Leary, Detection of measles virus in children with ileo-colonic lymphoid nodular hyperplasia, enterocolitis and developmental disorder, Molecular psychiatry, 7 Suppl 2, 2002, pS47-s48 Journal Article, 2002 DOI

O. Sheils, P. Smyth, S. Finn, E. C. Sweeney and J. J. O'Leary, RET/PTC rearrangements in Hashimoto's thyroiditis, International Journal of Surgical Pathology, 10, (2), 2002, p167-8; author reply 168-9 Journal Article, 2002 DOI

M. Ring, N. Bolger, M. O'Donnell, A. Malkin, N. Bermingham, E. Akpan, F. Mulcahy, M. J. Turner, M. Griffin and J. J. O'Leary, Evaluation of liquid-based cytology in cervical screening of high-risk populations: a split study of colposcopy and genito-urinary medicine populations, Cytopathology, 13, (3), 2002, p152-9 Journal Article, 2002 DOI

J. Skinner, K. Luettich, M. Ring, J. J. O'Leary and M. J. Turner, Fetal DNA in maternal circulation of first-trimester spontaneous abortions, Obstetrics and gynecology, 97, (3), 2001, p460-463 Journal Article, 2001 URL DOI

P. Smyth, O. Sheils, S. Finn, C. Martin, J. O'Leary and E. C. Sweeney, Real-time quantitative analysis of E-cadherin expression in ret/PTC-1-activated thyroid neoplasms, International Journal of Surgical Pathology , 9, (4), 2001, p265-272 Journal Article, 2001 URL

M. O'Donovan, I. Silva, V. Uhlmann, N. Bermingham, K. Luttich, C. Martin, O. Sheils, A. Killalea, C. Kenny, S. Pileri and J. J. O'Leary, Expression profile of human herpesvirus 8 (HHV-8) in pyothorax associated lymphoma and in effusion lymphoma, Molecular pathology, 54, (2), 2001, p80-85 Journal Article, 2001 URL DOI

O. M. Sheils, J. J. O'Leary and E. C. Sweeney, Assessment of ret/PTC-1 rearrangements in neoplastic thyroid tissue using TaqMan RT-PCR, The Journal of Pathology, 192, (1), 2000, p32-36 Journal Article, 2000 URL DOI

V. Uhlmann, M. Prasad, I. Silva, K. Luettich, L. Grande, L. Alonso, M. Thisted, K. J. Pluzek, J. Gorst, M. Ring, M. Sweeney, C. Kenny, C. Martin, J. Russell, N. Bermingham, M. O'Donovan, O. Sheils and J. J. O'Leary, Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei, Molecular pathology, 53, (1), 2000, p48-50 Journal Article, 2000 DOI URL

Sheils, O.M., O'Leary, J.J., Sweeney, E.C., Differentiation of multicentric origin from intra-organ metastatic spread of hepatocellular carcinomas by comparative genomic hybridization, Journal of Pathology, 192, (1), 2000, p43-51 Journal Article, 2000 DOI

J. O'Leary, M. Kennedy, D. Howells, I. Silva, V. Uhlmann, K. Luttich, S. Biddolph, S. Lucas, J. Russell, N. Bermingham, M. O'Donovan, M. Ring, C. Kenny, M. Sweeney, O. Sheils, C. Martin, S. Picton and K. Gatter, Cellular localisation of HHV-8 in Castleman's disease: is there a link with lymph node vascularity?, Journal of Clinical Pathology - Molecular Pathology, 53, (2), 2000, p69-76 Journal Article, 2000 URL DOI

J. J. O'Leary, V. Uhlmann and A. J. Wakefield, Measles virus and autism, Lancet, 356, (9231), 2000, p772 Journal Article, 2000 URL DOI

Hackett, N.R., Sawy, T.B., Lee, L.Y., Silva, I., O'Leary, J., Rosengart, T.K., Crystal, R.G., Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo , Molecular Therapy, 2, (6), 2000, p649-656 Journal Article, 2000 DOI

A. J. Wakefield, A. Anthony, S. H. Murch, M. Thomson, S. M. Montgomery, S. Davies, J. J. O'Leary, M. Berelowitz and J. A. Walker-Smith, Enterocolitis in children with developmental disorders, The American Journal of Gastroenterology, 95, (9), 2000, p2285-2295 Journal Article, 2000 DOI

J. J. O'Leary, M. Kennedy, K. Luttich, V. Uhlmann, I. Silva, J. Russell, O. Sheils, M. Ring, M. Sweeney, C. Kenny, N. Bermingham, C. Martin, M. O'Donovan, D. Howells, S. Picton and S. B. Lucas, Localisation of HHV-8 in AIDS related lymphadenopathy, Molecular Pathology, 53, (1), 2000, p43-47 Journal Article, 2000 DOI URL

Ely, S.A., Powers, J., Lewis, D., Chang, S., Rubio, A., O'Leary, J., Knowles, D.M., Kaposi's sarcoma-associated herpesvirus-positive primary effusion lymphoma arising in the subarachnoid space, Human Pathology, 30, (8), 1999, p981-984 Journal Article, 1999 DOI

M. O'Donovan, J. M. Russell, J. J. O'Leary, J. A. Gillan, M. P. Lawler and E. F. Gaffney, Abl expression, tumour grade, and apoptosis in chondrosarcoma, Molecular Pathology, 52, (6), 1999, p341-4 Journal Article, 1999 URL DOI

Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., O'Leary, J.J., CD40 upregulation is independent of HHV-8 in the pathogenesis of Kaposi's sarcoma , Journal of Clinical Pathology - Molecular Pathology, 52, (1), 1999, p32-36 Journal Article, 1999 DOI

Prasad, M.L., Hyjek, E., Giri, D.D., Ying, L., O'Leary, J.J., Hoda, S.A., Double immunolabeling with cytokeratin and smooth-muscle actin in confirming early invasive carcinoma of breast , American Journal of Surgical Pathology, 23, (2), 1999, p176-181 Journal Article, 1999 DOI

O'Leary, J.J., Shapiro, R.L., Ren, C.J., Chuang, N., Cohen, H.W., Potmesil, M., Antiangiogenic effects of camptothecin analogues 9-amino- 20(S)camptothecin, topotecan, and CPT-11 studied in the mouse cornea model , Clinical Cancer Research, 5, (1), 1999, p181-187 Journal Article, 1999 DOI

Kennedy, M.M., Biddolph, S., Lucas, S.B., Howells, D.D., Picton, S., O'D McGee, J., Silva, I., (...), O'Leary, J.J., Cyclin D1 expression and HHV8 in Kaposi sarcoma , Journal of Clinical Pathology, 52, (8), 1999, p569-573 Journal Article, 1999 DOI

O'Leary, J., Muggia, F.M., Camptothecins: A review of their development and schedules of administration, European Journal of Cancer , 34, (10), 1998, p1500-1508 Journal Article, 1998 DOI

O'Leary, J.J., Landers, R.J., Silva, I., Uhlmann, V., Crowley, M., Healy, I., Luttich, K., Molecular analysis of ras oncogenes in CIN III and in stage I and II invasive squamous cell carcinoma of the uterine cervix , Journal of Clinical Pathology, 51, (8), 1998, p576-582 Journal Article, 1998 DOI

O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., O'Donovan, M., Healy, V., Kealy, W.F., (...), Doyle, C.T., Human papillomavirus and mixed epithelial tumors of the endometrium , Human Pathology, 29, (4), 1998, p383-389 Journal Article, 1998 DOI

Kennedy, M.M., O'Leary, J.J., Oates, J.L., Lucas, S.B., Howells, D.D., Picton, S., McGee, J.O'D., Human herpes virus 8 (HHV-8) in Kaposi's sarcoma: Lack of association with Bcl-2 and p53 protein expression , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p155-159 Journal Article, 1998 DOI

O'Leary, J.J., Silva, I., Uhlmann, V., Prasad, M., Luttich, K., Maffei, A., Picton, S., HHV-8 in multiple myeloma: Is this the first paracrine model of human tumorigenesis and do Koch's postulates apply? , Journal of Clinical Pathology - Molecular Pathology, 51, (4), 1998, p201-203 Journal Article, 1998 URL

Uhlmann, V., Rolfs, A., Mix, E., Silva, I., Hully, J., Lu, L., Lohman, K., (...), O'Leary, J.J., A novel, rapid in cell RNA amplification technique for the detection of low copy mRNA transcripts, Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p160-163 Journal Article, 1998 DOI

O. Flore, S. Rafii, S. Ely, J. J. O'Leary, E. M. Hyjek and E. Cesarman, Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus, Nature, 394, (6693), 1998, p588-92 Journal Article, 1998 DOI URL

Kennedy, M.M., Cooper, K., Howells, D.D., Picton, S., Biddolph, S., Lucas, S.B., McGee, J.O'D., O'Leary, J.J., Identification of HHV8 in early Kaposi's sarcoma: Implications for Kaposi's sarcoma pathogenesis , Journal of Clinical Pathology - Molecular Pathology, 51, (1), 1998, p14-20 Journal Article, 1998 DOI

O'Leary, J., Volm, M., Wasserheit, C., Muggia, F., Searching for Predictive Molecular Markers: Taxanes in Adjuvant and Neoadjuvant Therapies for Breast Cancer , Oncology Reports, 12, (1 SUPPL.1), 1998, p23-27 Journal Article, 1998

Uhlmann, V., Silva, I., Luttich, K., Picton, S., O'Leary, J.J., In cell amplication , Journal of Clinical Pathology - Molecular Pathology, 51, (3), 1998, p119-130 Journal Article, 1998 URL

O'Leary, J.J., Engels, K., Dada, M.A., The polymerase chain reaction in pathology , Journal of Clinical Pathology, 50, (10), 1997, p805-810 Journal Article, 1997 URL

O'Leary, J.J., Kaposi's sarcoma associated herpes virus (KSHV/HHV 8) : Epidemiology, molecular biology and tissue distribution , Journal of Clinical Pathology - Molecular Pathology , 50, (1), 1997, p4-8 Journal Article, 1997 URL

Kennedy, M.M., Lucas, S.B., Russell-Jones, R., Howells, D.D., Picton, S.J., Bardon, A., Comley, I.L., (...), O'Leary, J.J., HHV8 and female Kaposi's sarcoma , Journal of Pathology, 183, (4), 1997, p447-452 Journal Article, 1997 DOI

O'Leary, J.J., Landers, R.J., Crowley, M., Healy, I., Kealy, W.F., Hogan, J., Doyle, C.T., Alterations in exon 1 of c-myc and expression of p62(c-myc) in cervical squamous cell carcinoma , Journal of Clinical Pathology , 50, (11), 1997, p896-903 Journal Article, 1997 DOI

O'Leary, J.J., Landers, R.J., Chetty, R., In situ amplification in cytological preparations , Cytopathology, 8, (3), 1997, p148-160 Journal Article, 1997

J. J. O'Leary, R. J. Landers, M. Crowley, I. Healy, W. F. Kealy, J. Hogan, C. Cullinane, P. Kelehan and C. T. Doyle, Genotypic mapping of HPV and assessment of EBV prevalence in endocervical lesions, Journal of Clinical Pathology, 50, (11), 1997, p904-910 Journal Article, 1997 DOI URL

Boshoff, C., Talbot, S., Kennedy, M., O'Leary, J., Schulz, T., Chang, Y., HHV8 and skin cancers in immunosuppressed patients. , Lancet, 348, (9020), 1996, p138 Journal Article, 1996

O'Leary, J.J., Chetty, R., Graham, A.K., McGee, J.O'D., In situ PCR: Pathologist's dream or nightmare? , Journal of Pathology, 178, (1), 1996, p11-20 Journal Article, 1996 DOI

Koreth, J., O'Leary, J.J., McGee, J.O., Microsatellites and PCR genomic analysis , Journal of Pathology, 178, (3), 1996, p239-248 Journal Article, 1996 DOI

O'Leary, J.J., Seeking the cause of Kaposi's sarcoma , Nature Medicine, 2, (8), 1996, p862-863 Journal Article, 1996 DOI

C. Boshoff, T. F. Schulz, M. M. Kennedy, A. K. Graham, C. Fisher, A. Thomas, J. O. McGee, R. A. Weiss and J. J. O'Leary, Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells, Nature Medicine, 1, (12), 1995, p1274-1278 Journal Article, 1995 DOI

Chetty, R., Slavin, J.L., O'Leary, J.J., Ansari, N.A., Gatter, K.C., Primary Hodgkin's disease of the lung , Pathology, 27, (2), 1995, p111-114 Journal Article, 1995 DOI

Chetty, R., O'Leary, J.J., Biddolph, S.C., Gatter, K.C., Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas , Journal of Clinical Pathology, 48, (3), 1995, p239-241 Journal Article, 1995 DOI

O'Leary, J.J., Browne, G., Landers, R., Crowley, M., Healy, I., Johnson, M.I., Doyle, C.T., New nucleic acid amplification techniques in diagnostic pathology, Journal of the European Academy of Dermatology and Venereology, 3, (1), 1994, p78-86 Journal Article, 1994 DOI

O'Leary, J.J., Browne, G., Landers, R.J., Crowley, M., Healy, I.B., Street, J.T., Pollock, A.M., (...), Doyle, C.T., The importance of fixation procedures on DNA template and its suitability for solution-phase polymerase chain reaction and PCR in situ hybridization , Histochemical Journal , 26, (4), 1994, p337-346 Journal Article, 1994 DOI

O'Leary, J.J., Browne, G., Johnson, M.I., Landers, R.J., Crowley, M., Healy, I., Street, J.T., (...), Doyle, C.T., PCR in situ hybridisation detection of HPV 16 in fixed CaSki and fixed SiHa cell lines, Journal of Clinical Pathology, 47, (10), 1994, p933-938 Journal Article, 1994 DOI

Landers, R.J., O'Leary, J.J., Crowley, M., Healy, I., Annis, P., Burke, L., O'Brien, D., (...), Doyle, C.T., Epstein-Barr virus in normal, pre-malignant, and malignant lesions of the uterine cervix , Journal of Clinical Pathology, 46, (10), 1993, p931-935 Journal Article, 1993 DOI

Doyle, C.T., O'Leary, J.J., The search for the universal fixative or 'magic juice' , Journal of Pathology , 166, (4), 1992, p331-332 Journal Article, 1992 DOI

Non-Peer-Reviewed Publications

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N, Endogenous thrombin potential as a marker for venous thrombosis in ovarian cancer., International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Published Abstract, 2012

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, O' Leary. J, Gleeson. N. , Why is venous thromboembolism is a common complication of ovarian cancer? , International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society. , Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Published Abstract, 2012

Abu Saadeh F, Norris L, O'Toole S, Langhe R, O'Leary JJ, Gleeson N., Does tissue factor and tissue factor pathway inhibitor over-expression play a role in the development of venous thromboembolism in ovarian cancer patients?, Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, ((Suppl 1)), Elsevier, 2012 Published Abstract, 2012

Abu Saadeh F, Norris L, O'Toole S, Langhe R, Gleeson N., Procoagulant activity in patients with gynecological malignancies and the effect of neoadjuvant chemotherapy , Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, (Suppl 1), Elsevier, 2012 Published Abstract, 2012

Research Expertise

Description

Biomarkers of disease. Cervical Cancer. Development of array technologies. Molecular pathology. Prostate cancer.

Keywords

Biomarkers of disease; Cervical Cancer; Development of array technologies; Molecular pathology; Prostate cancer

Recognition

Representations

Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes

Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms.

Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).

Invitee, Breast Cancer Consortium (Proposed), Investigators to be invited to participate in Breast Cancer workshop with a view to establishing formal consortium and informal individual collaborations.Last updated : 19 November 2004. Extract from DMMC Research Database