Martina Hennessy
Assoc Prof Consultant MedicalEducation, School Office - Medicine
Assoc Prof Consultant MedicalEducation, Pharmacology & Therapeutics

Publications and Further Research Outputs

Peer-Reviewed Publications

Kennedy A, Petrasca A, Doherty DG, Hennessy M, Spiers JP, HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or V"9V"2 T lymphocytes., AIDS (London, England), 28, (1), 2014, p131-3 Journal Article, 2014

Morris MC, Gillis AE, Smoothey CO, Hennessy M, Conlon KC, Ridgway PF, An Alternative Certification Examination ("ACE") in Surgery., Journal of surgical education, 2014, p779-789 Journal Article, 2014 DOI TARA - Full Text

Woods R, Ramasubbu B, Donohoe C, Hennessy M, Near-peer bedside clinical teaching: example of a successful programme., The clinical teacher, 11, (6), 2014, p472-7 Journal Article, 2014

Laragh Stevens, Maureen Kelly, Martina Hennessy, Jason Last, Fidelma Dunne, Siun O'Flynn , Medical Student Views on Selection Tools for Medicine- A mixed methods study. Accepted by Irish Medical Journal , Irish medical Journal , 2014, p229 - 231 Journal Article, 2014

Hennessy , Quinn, Annual Report: Development Studies Association of Ireland , Trinity College Dublin , 2014 Report, 2014

Svärd J, Blanco F, Nevin D, Fayne D, Mulcahy F, Hennessy M, Spiers JP, Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events., British journal of pharmacology, 171, (2), 2014, p480-97 Journal Article, 2014

HPAT Research group , National research group evaluating revised entry mechanisms to medicine, IUA/ CDFMSI, 2013, 24 pp Report, 2013

Morris M, Donohoe G, Hennessy M, O Ciardha C, Pro forma: impact on communication skills?, The clinical teacher, 10, (5), 2013, p318-22 Journal Article, 2013

O' Flynn S, Power Susan, Hennessy M, Mills A, Lapthorne S. , 'Guidance Counsellors perspectives on revised entry and selection mechanisms to medicine and the HPAT', Institute of Guidance Counsellors, 2013, - 7-10 Protocol or guideline, 2013

M Phillips, M Hennessy, A Patterson, Power and its Applications: a new module in the medical curriculum at Trinity College Dublin, Medical Humanities, 2013 Journal Article, 2013

Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M, Long-Term Statin Therapy in Patients With Systolic Heart Failure and Normal Cholesterol: Effects on Elevated Serum Markers of Collagen Turnover, Inflammation, and B-Type Natriuretic Peptide., Clinical therapeutics, 34, (1), 2012, p91 - 100 Journal Article, 2012

Rietz, A. Volkov, Y. Davies, A. Hennessy, M. Spiers, J., Okadaic acid induces MMP-9 expression in fibroblast: Crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling, British Journal of Pharmacology, 165, 2012, p274 - 288 Journal Article, 2012

Kennedy A, Hennessy M, Bergin C, Mulcahy F, Hopkins S, Spiers JP, Ribavirin and interferon alter MMP-9 abundance in vitro and in HIV-HCV-coinfected patients., Antiviral therapy, 16, (8), 2011, p1237-47 Journal Article, 2011

Phillips M, Pilkington R, Patterson A, Hennessy M, Death and dignity through fresh eyes., The clinical teacher, 8, (4), 2011, p241-244 Journal Article, 2011 DOI

McMahon CJ, Hennessy M, Boyle G, Feely J, Meaney JF, Prevalence of renal artery stenosis in flash pulmonary oedema: determination using gadolinium-enhanced MRA., European journal of internal medicine, 21, (5), 2010, p424-8 Journal Article, 2010

Svärd J, Spiers JP, Mulcahy F, Hennessy M, Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans., Journal of acquired immune deficiency syndromes (1999), 55, (5), 2010, p536-49 Journal Article, 2010

Molloy D, Molloy A, O'Loughlin C, Falconer M, Hennessy M, Inappropriate use of proton pump inhibitors., Irish journal of medical science, 179, (1), 2010, p73-5 Journal Article, 2010

Hennessy, M.; Spiers, J.P., A primer on the mechanics of P-glycoprotein the multi drug transporter, Pharmacological Research, 55, 2007, p1 - 15 Review Article, 2007

Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C, Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV medicine, 7, (4), 2006, p248-54 Journal Article, 2006

Song,G.; Hennessy,M.; Zhao,Y.L.; Li,Q.; Han,W.D.; Qi,Y.; Zhao,W.N.; Silke,B.; Barry,M.; Doyle,R.; Spiers,J.P., Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304), Pharmacological Research, 54, 2006, p57 - 64 Journal Article, 2006

Spiers,J.P.; Kelso,E.J.; Fong,S.; Edge,G.; Song,G.; McDermott,B.J.; Hennessy,M., Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade, Journal of Hypertension, 23, 2005, p1717 - 1724 Journal Article, 2005

Hennessy M, Clarke S, Spiers JP, Kelleher D, Mulcahy F, Hoggard P, Back D, Barry M, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients., Antiviral therapy, 9, (1), 2004, p115-22 Journal Article, 2004

Hennessy M, Clarke S, Spiers JP, Mulcahy F, Kelleher D, Meadon E, Maher B, Bergin C, Khoo S, Tjia J, Hoggard P, Back D, Barry M, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics., Antiviral therapy, 8, (3), 2003, p191-8 Journal Article, 2003

M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82 Journal Article, 2002 TARA - Full Text DOI URL

Mahmud A, Hennessy M, Feely J, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men., Journal of human hypertension, 15, (10), 2001, p707-13 Journal Article, 2001

Merry C, Barry MG, Ryan M, Tjia JF, Hennessy M, Eagling VA, Mulcahy F, Back DJ, Interaction of sildenafil and indinavir when co-administered to HIV-positive patients., AIDS (London, England), 13, (15), 1999, pF101-7 Journal Article, 1999

Hennessy M, Barry M, Drug interactions of clinical significance. , Irish Medical Times , 1999 Journal Article, 1999

Hennessy M, Feely J. , Understanding Drug Interactions. , Modern Medicine in Ireland , 1998 Journal Article, 1998

Non-Peer-Reviewed Publications

Martina Hennessy, Dawn Quinn , TIDI Impact report , Trinity College Dublin , July , 2014 Report, 2014

Martina Hennessy, Dawn Quinn, TIDI Impact Report , Trinity College Dublin , July , 2013 Report, 2013

Uduma, Hennessy , A Report on North South Experiences of Doctoral Training for Development in Africa, Trinity College dublin , November , 2012 Report, 2012

Uduma, Hennessy , Building Research Capacity in Higher Education Institutes through Partnerships with African Universities, Trinity College Dublin , November , 2012 Report, 2012

Feely J, Hennessy M, Sheehan O, 'Hypertension and Health a Patient Guide. ', Dept of Clinical Pharmacology and therapeutics , 2000, - Protocol or guideline, 2000

Research Expertise

Projects

  • Title
    • NOURISH :development of an irish-Ugandan HIV/ Nutrition research cluster Irish Aid / HEA
  • Funding Agency
    • Irish Aid / Hea
  • Date From
    • 2012
  • Date To
    • 2016
  • Title
    • Doctoral training for Development in Africa
  • Funding Agency
    • irish Aid/ HEA
  • Date From
    • 2008
  • Date To
    • 2014
  • Title
    • Establishment of a Dublin HIV Cohort Database
  • Funding Agency
    • HRB
  • Date From
    • 2005
  • Date To
    • 2010
  • Title
    • Role of the nuclear receptors (PXR and CAR) and thymidine kinase polymorphisms on the pharmacodynamics and pharmacokinetics of antiretroviral therapy in HIV disease
  • Summary
  • Funding Agency
    • European Clinical Aids Society
  • Date From
    • 2006
  • Date To
    • 2010
  • Title
    • Proposal to Expand and consolidate the Development Studies Association of Ireland in collaboration with TIDI
  • Funding Agency
    • Irish Aid
  • Date From
    • 2012
  • Date To
    • 2016
  • Title
    • Medicine 2 Research - Led teaching in Medicine
  • Summary
    • Thematic priority Research Led Teaching
  • Funding Agency
    • MEDINE 2 Network for Medical Education in Europe
  • Date From
    • 2009
  • Date To
    • 2012
  • Title
    • Development of an e-repository of integrative case studies
  • Summary
  • Funding Agency
    • Trinity College Dublin
  • Date From
    • 2008
  • Date To
    • 2010
  • Title
    • Curricular Reform of Medical Education in ireland
  • Summary
    • Non Peer Reviewed HEA funding for curricular reform and development of Academic Clinician Posts
  • Funding Agency
    • HEA
  • Date From
    • 2007
  • Date To
    • 2014
  • Title
    • Proposal for the establishment of a Medication Safety Team for St James's Hospital, Dublin
  • Summary
  • Funding Agency
    • HSE
  • Date From
    • 2003
  • Date To
    • Ongoing
  • Title
    • Development of interactive web based Continual assessment for pharmacology
  • Funding Agency
    • Trinity College
  • Date From
    • 2005
  • Date To
    • 2007
  • Title
    • Effect of ß-Adrenoceptor Antagonism on Plasma Matrix Metalloproteinase Activity and Oxidative State in Stable Heart Failure.
  • Funding Agency
    • Baggot Street Fund
  • Date From
    • 2001
  • Date To
    • 2004

Recognition

Representations

Member,Education sub-committee Medical Council representing University 2009- present

Chair,Medication safety committee St James's Hospital 2011-present

Member. Patient Safety committee Tallaght Hospital 2013-present

Member Board of Governance of Clinical Research Facility ST James's Hospital 2013-present

Member European Academic alliance in Global Health 2010- present

Internship oversight committee - representing the Trinity Network of Interns (123) 2011 - present

member of Eurolife International health committee representing university 2008-present

HEA Clinical Skills development advisory group 2008-2009

Irish University Medical School Consortium 2011- present

Awards and Honours

UCL Teaching Award, Royal Free and University College Medical School Academic 2006

Glaxo-Wellcome CPS Oral Communications Prize British Pharmacological Society, 2001. The role of the multi-drug transporter P-glycoprotein in HIV disease 2001

Bristol Myers Squibb Travel Scholarship Award British HIV Association, April 2001 The Clinical Implications of P-glycoprotein Expression and Function in HIV Positive Patients. 2001

Royal Academy of Medicine in Ireland Registrars prize (2nd) April 2001 The Role of P-glycoprotein Expression and Function in HIV Positive Patients. 2001

Glaxo-Wellcome Oral communications Prize British Pharmacological Society, Jan 2000 The Pharmacokinetics of Nelfinavir Administered Twice Versus Three Times Daily in HIV positive Patients. 2000

The Irish Association of Pharmacologists Oral communications prize, Nov 2000 A Role for P glycoprotein Expression and Function in Drug Interactions with St John's Wort. 2000

Society for Sexually Transmitted Diseases in Ireland Oral communications Prize April 2000. The Clinical Implications of Intracellular Protease Inhibitor Concentrations in HIV Patients. 2000

Professors prize in Paediatrics 1994

1st honours Medical Jurisprudence 5th medical year. 1993

Overall honours 2nd and 3rd medical years combined 1992

Distinction in Pharmacology 3rd medical year. 1992

Memberships

Fellow Royal college of Physicians in Ireland 2006 – present

Fellow Royal college of Physicians London 2007 – present

British Hypertension society initially as a student 2000 – present

British Pharmacological Society 1998 – present

Eurolife Network of Universities 2008 – present

Development Studies Association of Ireland 2012 – present

London Clinical Pharmacology group 2004 – 2010

British HIV Association 2003 – 2008