Martina Hennessy
Assoc Prof Consultant MedicalEducation, School Office - Medicine
Assoc Prof Consultant MedicalEducation, Pharmacology & Therapeutics
Publications and Further Research Outputs
Peer-Reviewed Publications
Woods R, Ramasubbu B, Donohoe C, Hennessy M, Near-peer bedside clinical teaching: example of a successful programme., The clinical teacher, 11, (6), 2014, p472-7
Morris MC, Gillis AE, Smoothey CO, Hennessy M, Conlon KC, Ridgway PF, An Alternative Certification Examination ("ACE") in Surgery., Journal of surgical education, 2014, p779-789
Laragh Stevens, Maureen Kelly, Martina Hennessy, Jason Last, Fidelma Dunne, Siun O'Flynn , Medical Student Views on Selection Tools for Medicine- A mixed methods study. Accepted by Irish Medical Journal , Irish medical Journal , 2014, p229 - 231
Hennessy , Quinn, Annual Report: Development Studies Association of Ireland , Trinity College Dublin , 2014
Kennedy A, Petrasca A, Doherty DG, Hennessy M, Spiers JP, HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or V"9V"2 T lymphocytes., AIDS (London, England), 28, (1), 2014, p131-3
Svärd J, Blanco F, Nevin D, Fayne D, Mulcahy F, Hennessy M, Spiers JP, Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events., British journal of pharmacology, 171, (2), 2014, p480-97
O' Flynn S, Power Susan, Hennessy M, Mills A, Lapthorne S. , 'Guidance Counsellors perspectives on revised entry and selection mechanisms to medicine and the HPAT', Institute of Guidance Counsellors, 2013, - 7-10
HPAT Research group , National research group evaluating revised entry mechanisms to medicine, IUA/ CDFMSI, 2013, 24 pp
Morris M, Donohoe G, Hennessy M, O Ciardha C, Pro forma: impact on communication skills?, The clinical teacher, 10, (5), 2013, p318-22
M Phillips, M Hennessy, A Patterson, Power and its Applications: a new module in the medical curriculum at Trinity College Dublin, Medical Humanities, 2013
Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M, Long-Term Statin Therapy in Patients With Systolic Heart Failure and Normal Cholesterol: Effects on Elevated Serum Markers of Collagen Turnover, Inflammation, and B-Type Natriuretic Peptide., Clinical therapeutics, 34, (1), 2012, p91 - 100
Rietz, A. Volkov, Y. Davies, A. Hennessy, M. Spiers, J., Okadaic acid induces MMP-9 expression in fibroblast: Crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling, British Journal of Pharmacology, 165, 2012, p274 - 288
Kennedy A, Hennessy M, Bergin C, Mulcahy F, Hopkins S, Spiers JP, Ribavirin and interferon alter MMP-9 abundance in vitro and in HIV-HCV-coinfected patients., Antiviral therapy, 16, (8), 2011, p1237-47
Phillips M, Pilkington R, Patterson A, Hennessy M, Death and dignity through fresh eyes., The clinical teacher, 8, (4), 2011, p241-244
Molloy D, Molloy A, O'Loughlin C, Falconer M, Hennessy M, Inappropriate use of proton pump inhibitors., Irish journal of medical science, 179, (1), 2010, p73-5
Svärd J, Spiers JP, Mulcahy F, Hennessy M, Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans., Journal of acquired immune deficiency syndromes (1999), 55, (5), 2010, p536-49
McMahon CJ, Hennessy M, Boyle G, Feely J, Meaney JF, Prevalence of renal artery stenosis in flash pulmonary oedema: determination using gadolinium-enhanced MRA., European journal of internal medicine, 21, (5), 2010, p424-8
Hennessy, M.; Spiers, J.P., A primer on the mechanics of P-glycoprotein the multi drug transporter, Pharmacological Research, 55, 2007, p1 - 15
Song,G.; Hennessy,M.; Zhao,Y.L.; Li,Q.; Han,W.D.; Qi,Y.; Zhao,W.N.; Silke,B.; Barry,M.; Doyle,R.; Spiers,J.P., Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304), Pharmacological Research, 54, 2006, p57 - 64
Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C, Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV medicine, 7, (4), 2006, p248-54
Spiers,J.P.; Kelso,E.J.; Fong,S.; Edge,G.; Song,G.; McDermott,B.J.; Hennessy,M., Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade, Journal of Hypertension, 23, 2005, p1717 - 1724
Hennessy M, Clarke S, Spiers JP, Kelleher D, Mulcahy F, Hoggard P, Back D, Barry M, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients., Antiviral therapy, 9, (1), 2004, p115-22
Hennessy M, Clarke S, Spiers JP, Mulcahy F, Kelleher D, Meadon E, Maher B, Bergin C, Khoo S, Tjia J, Hoggard P, Back D, Barry M, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics., Antiviral therapy, 8, (3), 2003, p191-8
M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82
Mahmud A, Hennessy M, Feely J, Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men., Journal of human hypertension, 15, (10), 2001, p707-13
Merry C, Barry MG, Ryan M, Tjia JF, Hennessy M, Eagling VA, Mulcahy F, Back DJ, Interaction of sildenafil and indinavir when co-administered to HIV-positive patients., AIDS (London, England), 13, (15), 1999, pF101-7
Hennessy M, Barry M, Drug interactions of clinical significance. , Irish Medical Times , 1999
Hennessy M, Feely J. , Understanding Drug Interactions. , Modern Medicine in Ireland , 1998
Non-Peer-Reviewed Publications
Martina Hennessy, Dawn Quinn , TIDI Impact report , Trinity College Dublin , July , 2014
Martina Hennessy, Dawn Quinn, TIDI Impact Report , Trinity College Dublin , July , 2013
Uduma, Hennessy , A Report on North South Experiences of Doctoral Training for Development in Africa, Trinity College dublin , November , 2012
Uduma, Hennessy , Building Research Capacity in Higher Education Institutes through Partnerships with African Universities, Trinity College Dublin , November , 2012
Feely J, Hennessy M, Sheehan O, 'Hypertension and Health a Patient Guide. ', Dept of Clinical Pharmacology and therapeutics , 2000, -
Research Expertise
Projects
- Title
- NOURISH :development of an irish-Ugandan HIV/ Nutrition research cluster Irish Aid / HEA
- Funding Agency
- Irish Aid / Hea
- Date From
- 2012
- Date To
- 2016
- Title
- Doctoral training for Development in Africa
- Funding Agency
- irish Aid/ HEA
- Date From
- 2008
- Date To
- 2014
- Title
- Establishment of a Dublin HIV Cohort Database
- Funding Agency
- HRB
- Date From
- 2005
- Date To
- 2010
- Title
- Role of the nuclear receptors (PXR and CAR) and thymidine kinase polymorphisms on the pharmacodynamics and pharmacokinetics of antiretroviral therapy in HIV disease
- Summary
- Funding Agency
- European Clinical Aids Society
- Date From
- 2006
- Date To
- 2010
- Title
- Proposal to Expand and consolidate the Development Studies Association of Ireland in collaboration with TIDI
- Funding Agency
- Irish Aid
- Date From
- 2012
- Date To
- 2016
- Title
- Medicine 2 Research - Led teaching in Medicine
- Summary
- Thematic priority Research Led Teaching
- Funding Agency
- MEDINE 2 Network for Medical Education in Europe
- Date From
- 2009
- Date To
- 2012
- Title
- Development of an e-repository of integrative case studies
- Summary
- Funding Agency
- Trinity College Dublin
- Date From
- 2008
- Date To
- 2010
- Title
- Curricular Reform of Medical Education in ireland
- Summary
- Non Peer Reviewed HEA funding for curricular reform and development of Academic Clinician Posts
- Funding Agency
- HEA
- Date From
- 2007
- Date To
- 2014
- Title
- Proposal for the establishment of a Medication Safety Team for St James's Hospital, Dublin
- Summary
- Funding Agency
- HSE
- Date From
- 2003
- Date To
- Ongoing
- Title
- Development of interactive web based Continual assessment for pharmacology
- Funding Agency
- Trinity College
- Date From
- 2005
- Date To
- 2007
- Title
- Effect of ß-Adrenoceptor Antagonism on Plasma Matrix Metalloproteinase Activity and Oxidative State in Stable Heart Failure.
- Funding Agency
- Baggot Street Fund
- Date From
- 2001
- Date To
- 2004
Recognition
Representations
Member,Education sub-committee Medical Council representing University
Chair,Medication safety committee St James's Hospital
Member. Patient Safety committee Tallaght Hospital
Member Board of Governance of Clinical Research Facility ST James's Hospital
Member European Academic alliance in Global Health
Internship oversight committee - representing the Trinity Network of Interns (123)
member of Eurolife International health committee representing university
HEA Clinical Skills development advisory group
Irish University Medical School Consortium
Awards and Honours
UCL Teaching Award, Royal Free and University College Medical School Academic
Glaxo-Wellcome CPS Oral Communications Prize British Pharmacological Society, 2001. The role of the multi-drug transporter P-glycoprotein in HIV disease
Bristol Myers Squibb Travel Scholarship Award British HIV Association, April 2001 The Clinical Implications of P-glycoprotein Expression and Function in HIV Positive Patients.
Royal Academy of Medicine in Ireland Registrars prize (2nd) April 2001 The Role of P-glycoprotein Expression and Function in HIV Positive Patients.
Glaxo-Wellcome Oral communications Prize British Pharmacological Society, Jan 2000 The Pharmacokinetics of Nelfinavir Administered Twice Versus Three Times Daily in HIV positive Patients.
The Irish Association of Pharmacologists Oral communications prize, Nov 2000 A Role for P glycoprotein Expression and Function in Drug Interactions with St John's Wort.
Society for Sexually Transmitted Diseases in Ireland Oral communications Prize April 2000. The Clinical Implications of Intracellular Protease Inhibitor Concentrations in HIV Patients.
Professors prize in Paediatrics
1st honours Medical Jurisprudence 5th medical year.
Overall honours 2nd and 3rd medical years combined
Distinction in Pharmacology 3rd medical year.
Memberships
Fellow Royal college of Physicians in Ireland
Fellow Royal college of Physicians London
British Hypertension society initially as a student
British Pharmacological Society
Eurolife Network of Universities
Development Studies Association of Ireland
London Clinical Pharmacology group
British HIV Association