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Dr. John Butler
Adjunct Assistant Professor, Physiology

Biography

My eight years of basic and translational research combined at the Max Planck Institute for Biological Cybernetics (Tuebingen, Germany) and the Albert Einstein College of Medicine (New York, USA) with my Ph.D. in Numerical Methods from Trinity College Dublin gives me a unique set of skills and ideas when approaching Neural Engineering and Neuroscience research questions.

Publications and Further Research Outputs

Peer-Reviewed Publications

Molloy A, Kimmich O, Williams L, Butler JS, Byrne N, Molloy F, Moore H, Healy DG, Lynch T, Edwards MJ, Walsh C, Reilly RB, O'Riordan S, Hutchinson M, An evaluation of the role of environmental factors in the disease penetrance of cervical dystonia., Journal of neurology, neurosurgery, and psychiatry, 86, (3), 2015, p331-335 Journal Article, 2015 DOI

Andrade GN, Molholm S, Butler JS, Brandwein AB, Walkley SU, Foxe JJ, Atypical multisensory integration in Niemann-Pick type C disease - towards potential biomarkers., Orphanet journal of rare diseases, 9, 2014, p149 Journal Article, 2014 TARA - Full Text

Molloy A, Kimmich O, Williams L, Quinlivan B, Dabacan A, Fanning A, Butler JS, O'Riordan S, Reilly RB, Hutchinson M, A headset method for measuring the visual temporal discrimination threshold in cervical dystonia., Tremor and other hyperkinetic movements (New York, N.Y.), 4, 2014, p249 Journal Article, 2014 DOI TARA - Full Text

Brandwein AB, Foxe JJ, Butler JS, Frey HP, Bates JC, Shulman LH, Molholm S, Neurophysiological Indices of Atypical Auditory Processing and Multisensory Integration are Associated with Symptom Severity in Autism., Journal of autism and developmental disorders, 2014 Journal Article, 2014

De Sanctis P, Butler JS, Malcolm BR, Foxe JJ, Recalibration of inhibitory control systems during walking-related dual-task interference: a mobile brain-body imaging (MOBI) study., NeuroImage, 94, 2014, p55-64 Journal Article, 2014

Butler JS, Campos JL, Bülthoff HH, Optimal visual-vestibular integration under conditions of conflicting intersensory motion profiles., Experimental brain research, 2014 Journal Article, 2014

Hutchinson M, Isa T, Molloy A, Kimmich O, Williams L, Molloy F, Moore H, Healy DG, Lynch T, Walsh C, Butler J, Reilly RB, Walsh R, O'Riordan S, Cervical dystonia: a disorder of the midbrain network for covert attentional orienting., Frontiers in neurology, 5, 2014, p54 Journal Article, 2014 TARA - Full Text DOI

Mercier MR, Foxe JJ, Fiebelkorn IC, Butler JS, Schwartz TH, Molholm S, Auditory-driven phase reset in visual cortex: human electrocorticography reveals mechanisms of early multisensory integration., NeuroImage, 79, 2013, p19-29 Journal Article, 2013

Butler JS, Foxe JJ, Fiebelkorn IC, Mercier MR, Molholm S, Multisensory representation of frequency across audition and touch: high density electrical mapping reveals early sensory-perceptual coupling., The Journal of neuroscience : the official journal of the Society for Neuroscience, 32, (44), 2012, p15338-44 Journal Article, 2012

Research Expertise

Description

My research is focused on investigating how the brain processes sensory and multisensory cues in clinical and non-clinical populations. To do this I design novel experimental protocols and adapt/build experimental equipment to acquire behavioural and neurophysiological data. I devise advanced signal processing methods to analyze and interpret these rich and complex datasets. I have used this data to develop biologically plausible and computational elegant models that describe the integration of sensory signals. As a Senior Research Fellow I will extend these models to make predictions of abhorrent sensory signal processing that has been observed in clinical populations. These modelsare tested and help bridge the gap between theoretical hypothesis and experimental data which is vital to further our understanding of normal and abnormal sensory processing. This will be conducted in collaboration with my research partners who investigate Dystonia (Prof Michael Hutchison, St. Vincent's University Hospital) and Parkinson's disease (Prof. Tim Lynch, Mater Hospital)
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