Henry Windle
Asst Prof in Molecular Medicine, Clinical Medicine
Asst Prof in Molecular Medicine, Molecular Medicine Ireland

Publications and Further Research Outputs

Peer-Reviewed Publications

Lynch M, Walsh TA, Marszalowska I, Webb AE, MacAogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE., Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 2017 Journal Article, 2017 DOI

Xiaofang Liu, Helena Jahuira, Robert Gilman, Alicia Alva, Lilia Cabrera, Michiko Okamoto, Hang Xu, Dermot Kelleher, Henry Windle, Marco Varela, Manuela Verastegui, Maritza Calderon, Gerardo Sanchez, Vanessa Sarabia, Sarah Ballard, Caryn Bern, Holger Mayta, Jean Crabtree, Vita Cama, Mayuko Saito, and Hitoshi Oshitani , Etiological role and repeated infections of sapovirus among children aged less than two years in a cohort study in a peri-urban community of Peru, Journal of Clinical Microbiology, 54, (6), 2016, p1598-604 Journal Article, 2016 DOI

Burrows, A.D., Jurcic, M., Mahon, M.F., Pierrat, S., Roffe, G.W., Windle, H.J., Spencer, J., Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity., Dalton Transactions, 44, (31), 2015, p13814 - 13817 Journal Article, 2015 DOI

D Jaganath, M Saito, RH Gilman, V Cama, L Cabrera, D Kelleher, H Windle, J Crabtree, W Checkley, First detected Helicobacter pylori infection in infancy modifies the association between diarrheal disease and childhood growth in Peru, Helicobacter, 2014 Journal Article, 2014 TARA - Full Text

Saito M, Goel-Apaza S, Espetia S, Velasquez D, Cabrera L, Loli S, Crabtree JE, Black RE, Kosek M, Checkley W, Zimic M, Bern C, Cama V, Gilman RH; The Norovirus Working Group in Peru (Xiao L, Kelleher D, Windle HJ, van Doorn LJ, Varela M, Verastegui M, Calderon M, Alva A, Roman K), Multiple norovirus infections in a birth cohort in a Peruvian peri-urban community., Clin Infect Dis. , 58, (4), 2014, p483 - 491 Journal Article, 2014 DOI TARA - Full Text

L.E. Collins, M Lynch, I Marszalowska, M. Kristek, K. Rochfort, M. O'Connell, H.J. Windle, D. Kelleher, C.E. Loscher, Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages, Microbes and Infection, 2014 Journal Article, 2014 DOI TARA - Full Text

Sing A, Windle HJ, Cornally D, Ryan B, Henehan GT., A Short-Chain NAD(H)-Dependent Alcohol dehydrogenase (HpSCADH) from Helicobactor pylori: A role in growth under neutral and acidic conditions., The International Journal of Biochemistry & Cell Biology, 45, (7), 2013, p1347-1355 Journal Article, 2013

Harris PR, Serrano CA, Villagrán A, Malker MM, Thomson M, Duarte I, Windle HJ, Crabtree JE , Helicobacter pylori-associated hypochlorohydria in children relates to the development of iron deficiency. , Journal of Clinical Pathology, 66, (4), 2013, p343 - 347 Journal Article, 2013 DOI

Queiroz DMM, Harris PR, Sanderson IR, Windle HJ, Walker MM, Rocha AMC, Rocha GA, Carvalho SD, Bittencourt PFS, de Castro LPF, Cillagran A, Serrano C, Kelleher D, Crabtree JE, Iron status and Helicobacter pylori infection in children: an international multi-centered study , PlosOne, 8, (7), 2013, pe6883- Journal Article, 2013

Gavin J, Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF., Structure requirements for anaerobe processing of azo compounds: implications for prodrug design., Bioorganic and Medicinal Chemistry Letters, 22, (24), 2013, p7647-7652 Journal Article, 2013 DOI

Marquez Ruiz JF, Kedziora K, Pigott M, Keogh B, Windle H, Gavin J, Kelleher DP, Gilmer JF., A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib., Bioorg Med Chem Lett, 23, (6), 2013, p1693-8 Journal Article, 2013 DOI

Queiroz, D.M.M., Harris, P.R., Sanderson, I.R., Windle, H.J., Walker, M.M., Rocha, A.M.C., Rocha, G.A., (...), Crabtree, J.E, Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study, PLoS ONE , 8, (7), 2013, art. no. e68833 Journal Article, 2013 TARA - Full Text DOI

Marquez Ruiz JF, Kedziora K, O'Reilly M, Maguire J, Keogh B, Windle HJ, Kelleher D, Gilmer JF, Azo-reductase activated budesodine prodrugs for colon targeting, Bioorganic and Medicinal Chemistry Letters, 22, (24), 2012, p7573 - 7577 Journal Article, 2012

O'Riordan AA, Morales V, Mulligan L, Faheem N, *Windle HJ, *Kelleher D, Alkyl Hydroperoxide reductase: a candidate Helicobacter pylori vaccine, Vaccine, 30 , (26), 2012, p3876 - 3884 Journal Article, 2012

O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP, Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine., Vaccine, 30, (26), 2012, p3876-84 Journal Article, 2012 DOI

Gavin J, Ruiz JFM, Kedziora K, Windle HJ, Kelleher D, Gilmer JF, Structure requirements for anaerobe processing of azo compounds: implications for prodrug design, Biooranic and Medicinal Chemistry Letters, 22 , (24), 2012, p7647 - 7652 Journal Article, 2012

Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle H, Kelleher DP, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors., Bioorganic & medicinal chemistry letters, 21, (22), 2011, p6636-40 Journal Article, 2011 DOI

Smith SM, Moran AP, Duggan SP, Ahmed SE, Mohamed AS, Windle HJ, O'Neill LA, Kelleher DP, Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide., Journal of immunology (Baltimore, Md. : 1950), 186, (4), 2011, p2462-2671 Journal Article, 2011 DOI

Smith SM, Moran AP, Duggan S, Ahmed SE, Mohamed AS, Windle HJ, O'Neill L, and Kelleher D., Tribbles 3: A Novel Regulator of TLR2-Mediated Signaling in Response to Helicobacter pylori Lipopolysaccharide , Journal of Immunology, 186, (4), 2011, p2462 - 2471 Journal Article, 2011 URL

Marquez Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle HJ, Kelleher D, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors, Bioorganic & Medicinal Chemistry Letters, 21, (22), 2011, p6636-6640 Journal Article, 2011 TARA - Full Text

Ruiz JF, Kedziora K, Windle HJ, Kelleher DP, Gilmer JF., Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., J. Pharm. Pharmacol., 63, (6), 2011, p806 - 816 Journal Article, 2011

Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF, Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., The Journal of pharmacy and pharmacology, 63, (6), 2011, p806-816 Journal Article, 2011 DOI

Windle HJ, Brown PA, Kelleher D, Proteomics of Bacterial Pathogenicity: therapeutic implications, Proteomics - Clinical Applications, 4, (2), 2010, p1-13 Review, 2010

Lee G, Cama V, Gilman RH, Cabrera L, Saito M, Checkley W; CONTENT Investigators (Kelleher D, Windle H, Crabtree J), Comparison of two types of epidemiological surveys aimed at collecting daily clinical symptoms in community-based longitudinal studies., Ann Epidemiol., 20, (2), 2010, p151 - 158 Journal Article, 2010

Brown P, Smith S, Botting C, Kelleher D, Windle HJ, H. pylori outer membrane vesicles modulate proinflammatory and other signalling pathways in gastric and non-gastric cells , Helicobacter, Rotterdam, Netherlands, 15, (4), 2010, pp321 - 321 Meeting Abstract, 2010

Smith SM, Mullaney E, Duggan SP, Windle HJ, O'Neill LA, Kelleher D. , Toll-like Receptor 2-dependent Chemokine Induction in Epithelial Cells by Lipopolysaccharide Contained in Helicobacter pylori Outer Membrane Vesicles, Gastroenterology, American Gastroenterology association, DDW, Chicago, USA, 2009 Meeting Abstract, 2009

Mullaney E, Brown PA, Smith S, Botting CH, Yamoka Y, Terres AM, Kelleher DP, Windle HJ, Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori, Proteomics Clin Appl, 3, (7), 2009, p785 - 796 Journal Article, 2009

Ruiz Marquez JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer GF, Design, Synthesis, and Pharmacological Effects of a Cyclization-activated Steroid Prodrug for Colon Targeting in Inflammatory Bowel Disease, Journal of Medicinal Chemistry, 52, (10), 2009, p3205 - 3211 Journal Article, 2009 DOI

Abdel-Latif MM, Windle HJ, Davies A, Volkov Y, Kelleher D., A new mechanism of gastric epithelial injury induced by acid exposure: the role of Egr-1 and ERK signaling pathways., Journal of Cellular Biochemistry, 108, 2009, p249 - 160 Journal Article, 2009

Villagran A., Serrano C., Torres J., Duarte I., Windle HJ., Crabtree JE. Harris PR , Gastric pH and its relationship with H. pylori infection and serum iron in children., World congress of paediatric gastroenterology, hepatology and nutrition., Iguassu Falls, Brazil, 16-20 Aug 2008, 2008 Meeting Abstract, 2008

Villagran A, Serrano C, Torres J, Duarte I, Windle H, Crabtree J, Harris P., Alteraciones en el perfil serico de Hierro en ninos infectados por Helicobacter pylori, Gastroenterologia Latinoamericana, Chile, 2008, edited by Caffri C, Pino RQ , 19, 2008 Meeting Abstract, 2008

Harris P, Villagran A, Serrano C, Torres J, Duarte I, Crabtree J, Windle HJ, Helicobacter pylori infection alters iron metabolism in Chilean children, 9th Venezuelan Congress of Microbiology, Valencia, Venezuela, 12-15 November 2008, 2008 Conference Paper, 2008

Cornally D, Mee B, MacDonaill C, Tipton KF, Kelleher D, Windle HJ, Henehan G, Aldo-Keto Reductase from Helicobacter pylori: role in adaptation to growth at acid pH, FEBS J, 275, (12), 2008, p3041 - 3050 Journal Article, 2008

Finn D., Hearty S, O'Kennedy R, Kelleher D, Windle H, Increased adhesion of H. pylori to laminin under iron reduced conditions., Gastroenterology, American Gastroenterology association, DDW, Washington, USA, 2007 Meeting Abstract, 2007

Windle HJ, Kelleher D, Crabtree JE, Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle?, Pediatrics, 119, (3), 2007, p754 - 759 Journal Article, 2007 TARA - Full Text DOI

Mullaney, EM, Botting, CH, Windle, HJ, Terres, AM, Kelleher, DP, Characterization of the Proteome of Helicobacter pylori Outer Membrane Vesicles, Gastroenterology , American Gastroenterology association, DDW, Los Angeles, USA, 2006, 130, (4), 2006 Meeting Abstract, 2006

McGee DJ, Kumar S, Viator RJ, Bolland JR, Ruiz J, Spadafora D, Testermn TL, Kelly DJ, Pannell LK, Windle HJ, Helicobacter pylori thioredoxin is an arginase chaperone and guardian against oxidative and nitrosative stresses, J. Biol. Chem., 281, (6), 2006, p3290 - 3296 Journal Article, 2006

Abdel-Latif MM, Windle H, Terres A, Eidhin DN, Kelleher D, Reynolds JV., Helicobacter pylori Extract Induces Nuclear Factor-kappa B, Activator Protein-1, and Cyclooxygenase-2 in Esophageal Epithelial Cells., J Gastrointest Surg. , 10, (4), 2006, p551 - 562 Journal Article, 2006

Papinutto E, Windle HJ, Cendron L, Battistutta R, Kelleher D., Crystal Structure of alkyl hydroperoxide reductase (AphC) from Helicobacter pylori, Biochim Biophys Acta, 1753, 2005, p240 - 246 Journal Article, 2005

Windle HJ*, Ang YS*, Athie Morales V, McManus R*, Kelleher DP , Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32 Journal Article, 2005 DOI TARA - Full Text

O'Toole D, Abdel-Latif MM, Long A, Windle HJ, Murphy AM, Bowie A, O'neill LA, Weir DG, Kelleher D., Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: A common pathway for epithelial cell injury?, J Cell Biochem., 96, (3), 2005, p589 - 598 Journal Article, 2005

Windle HJ, Ang YS, Morales VA, McManus R, Kelleher D, Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32 Journal Article, 2005

Abdel Latif MM, Windle HJ, El Homasany BS, Sabra K, Kelleher D, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells., British Journal of Pharmacology, 146, 2005, p1139 - 1147 Journal Article, 2005

B Mee, D Kelleher, J Frias, R Malone, KF Tipton, GT Henehan, HJ Windle, Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme, FEBS J, 272, (5), 2005, p1255 - 1264 Journal Article, 2005 TARA - Full Text DOI

B. Mee, D. Kelleher, J. Frias, R. Malone, K.F. Tipton, G.T. Henehan, H.J. Windle., Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori: an aldehyde dismutating enzyme., FEBS J., 272, (5), 2005, p1255 - 1264 Journal Article, 2005

Mohamed MM Abdel-Latif, Henry J Windle, Basma S El Homasany, Kamal Sabra, Dermot Kelleher, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells, British Journal of Pharmacology, 146, (8), 2005, p1139 - 1147 Journal Article, 2005 TARA - Full Text

M. M. Abdel-Latif, H. J. Windle, K. A. Fitzgerald, Y. S. Ang, D. N. Eidhin, M. Li-Weber, K. Sabra and D. Kelleher, Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells, Infection and immunity, 72, (6), 2004, p3549-60 Journal Article, 2004 URL

M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of Surgery, 239, (4), 2004, p491-500 Journal Article, 2004 DOI TARA - Full Text

M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of surgery, 239, (4), 2004, p491-500 Journal Article, 2004 URL

Abdel-Latif MM, Windle HJ, Fitzgerald KA, Ang YS, Eidhin DN, Li-Weber M, Sabra K, Kelleher D., Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells., Infect. Immun., 72, (6), 2004, p3549 - 3560 Journal Article, 2004

A. M. Terres, H. J. Windle, E. Ardini and D. P. Kelleher, Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner, Infection and immunity, 71, (7), 2003, p4067-78 Journal Article, 2003 DOI TARA - Full Text

Filson H, Fox A, Kelleher D, Windle HJ, Sanders DA. , Purification, crystallization and preliminary X-ray analysis of an unusual thioredoxin from the gastric pathogen Helicobacter pylori., Acta Crystallogr D Biol Crystallogr, 59, (7), 2003, p1280 - 1282 Journal Article, 2003

Terres AM, Windle HJ, Ardini E, Kelleher DP., Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner., Infect. Immun., 71, (7), 2003, p4067 - 4078 Journal Article, 2003

Henry Windle, Ross McManus, Dermot Kelleher, A vaccine for Helicobacter pylori , 2002 Patent, 2002

Immunological aspects of H. pylori infection in, Mahida YR , Immunological Aspects of Gastroenterology, The Netherlands, Kluwer Academic Publishers, 2001, pp153 - 175, [Windle HJ, Terrés AM & Kelleher D.] Book Chapter, 2001

M. B. Redpath, H. Windle, D. Nolan, E. Pays, H. P. Voorheis and M. Carrington, ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei, Molecular and biochemical parasitology, 111, (1), 2000, p223-8 Journal Article, 2000 URL

Windle HJ, Fox A, Ni Eidhin D, Kelleher D., The thioredoxin system of Helicobacter pylori., J. Biol. Chem., 275, (7), 2000, p5081 - 5090 Journal Article, 2000

Redpath MB, Windle H, Nolan D, Pays E, Voorheis HP, Carrington M, ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei., Molecular and biochemical parasitology, 111, (1), 2000, p223-228 Journal Article, 2000 DOI

Redpath MB, Windle H, Nolan D, Pays E, Voorheis HP, Carrington M., ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei., Mol Biochem Parasitol, 111, (1), 2000, p223 - 228 Journal Article, 2000

Windle HJ, Kelleher D. , Identification and characterization of a metalloprotease activity from Helicobacter pylori., Infect. Immun., 65, (8), 1997, p3132 - 3137 Journal Article, 1997

Nolan, D., Jackson, D. G., Windle, H. J., Pays, A., Geuskens, M., Michel, A., Voorheis, H. P. and Pays, E., Characterization of a novel, stage-specific, invariant surface protein in Trypanosoma brucei containing an internal, serine-rich, repetitive motif, Journal of Biological Chemistry, 272, (46), 1997, p29212 - 29221 Journal Article, 1997 DOI

D. P. Nolan, D. G. Jackson, H. J. Windle, A. Pays, M. Geuskens, A. Michel, H. P. Voorheis and E. Pays, Characterization of a novel, stage-specific, invariant surface protein in Trypanosoma brucei containing an internal, serine-rich, repetitive motif, The Journal of biological chemistry, 272, (46), 1997, p29212-21 Journal Article, 1997 URL

Human immune responses to Helicobacter pylori infections in, Moran AP & O'Morain CA , Pathogenesis and Host Response in Helicobacter pylori infections, Normed Verlag, 1997, pp148 - 157, [Kelleher D, Windle HJ & Fan XJ] Book Chapter, 1997

H. X. Xia, H. J. Windle, D. G. Marshall, C. J. Smyth, C. T. Keane and C. A. O'Morain, Recrudescence of Helicobacter pylori after apparently successful eradication: novel application of randomly amplified polymorphic DNA fingerprinting, Gut, 37, (1), 1995, p30-Apr Journal Article, 1995 URL

D. G. Jackson, H. J. Windle and H. P. Voorheis, The identification, purification, and characterization of two invariant surface glycoproteins located beneath the surface coat barrier of bloodstream forms of Trypanosoma brucei, The Journal of biological chemistry, 268, (11), 1993, p8085-95 Journal Article, 1993 URL

Doherty, M. L., Windle, H. J., Voorheis, H. P., Larkin, H., Casey, M., Clery, D. & Murray, M., Clinical disease associated with Trypanosoma theileri infection in a calf in Ireland, Veterinary Record , 132, (26), 1993, p653 - 656 Journal Article, 1993

M. L. Doherty, H. Windle, H. P. Voorheis, H. Larkin, M. Casey, D. Clery and M. Murray, Clinical disease associated with Trypanosoma theileri infection in a calf in Ireland, The Veterinary record, 132, (26), 1993, p653-6 Journal Article, 1993 URL

Jackson, D. J., Windle, H. J. & Voorheis, H. P., The Identification, Purification and Characterization of Two Invariant Surface Glycoproteins Located beneath the Surface Coat Barrier of Bloodstream Forms of T. brucei, Journal of Biological Chemistry, 268, (11), 1993, p8085 - 8095 Journal Article, 1993 URL

Research Expertise

Description

Infectious pathogens: Helicobacter pylori, Fusobacterium nucleatum, Campylobacter showae, Clostridium difficile

Projects

  • Title
    • Evaluation and Control of Neglected Mucosal Enteric Infections in Childhood
  • Summary
    • Microbial enteric pathogens are a major cause of childhood morbidity world-wide, contributing to impaired growth and cognitive function. In developing countries the diversity of childhood enteric infections makes diagnosis and disease surveillance difficult. To date there has been limited data on the impact of the major childhood infection Helicobacter pylori on global health issues in children in underdeveloped regions of the world. Initial infection with H. pylori is associated with a period of hypochlorhydria (reduced acid secretion), which we hypothesise is critical for the aquistion of other enteric infections, diarrhoeal disease and impaired childhood growth. In addition, we hypothesise that gastric H. pylori infection is a contributory factor to iron deficiency anaemia in childhood. The objective of the CONTENT project is to improve knowledge and apply new technologies to improve the control of neglected enteric pathogens in socio-economically disadvantaged childhood populations of Latin America
  • Funding Agency
    • European Union
  • Date From
    • 2006
  • Date To
    • 2010
  • Title
    • Evaluation of the carcinogenic potential of Fusobacterium nucleatum
  • Summary
    • Identification of the constituent bacterial species of the intestinal microbiota under normal and disease conditions has led to the identification of associations between dysbiosis and several chronic disease states. In this regard, an association between the bacterium Fusobacterium nucleatum and intestinal cancer has been identified. Originally this organism was identified as an oral pathogen responsible in part for periodontitis but now is found to be significantly associated with several extraoral dieases, including colon cancer. Interestingly, this pathogen is also enriched at sites of adenoma formation, the precursors of carcinoma, suggesting that it may be a primary initiator of carcinogenesis. Although causality has not yet been established there is compelling evidence indicating a primary role for this pathogen in disease progression. This project aims to investigate the pathogenic/carcinogenic potential of F. nucleatum using in vitro models by evaluating its ability to induce a pro-inflammatory environment and modulate/subvert cellular signalling pathways.
  • Funding Agency
    • Dept of Education, Government of Saudi Arabia
  • Date From
    • 2013
  • Date To
    • 2016
  • Title
    • Development of Clostridium difficile vaccine
  • Funding Agency
    • Enterprise Ireland
  • Date From
    • 2002
  • Date To
    • 2005
  • Title
    • Development of a Helicobacter pylori vaccine
  • Funding Agency
    • Enterprise Ireland
  • Date From
    • 2009
  • Date To
    • 2010

Keywords

Bacterial pathogenicity; Fusobacterium nucleatum; GASTRIC CANCER; Helicobacter pylori; Host-pathogen interaction; Identification of vaccine candidates; in vitro models of infection; Infectious diseases; Innate and acquired resistance to infection; Innate Immunity; Parasitology and parasitic diseases; Protein chemistry, structure and folding; Proteomics; Vaccines

Recognition

Representations

Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.

Member, Centre for Research into Global Disease (Proposed), This consortium combines researchers with complementary interests in globally significant infectious disease. Interests include innate immunity, immune regulation, regional immunity, immune evasiob, vaccine & adjuvant development as well as drug & target development.

Member, Cycle 2 PI's & Researchers, All Cycle 2 Researchers & PI's

Memberships

Biochemical Society