Noreen Gleeson
Associate Professor, Obstetrics

Publications and Further Research Outputs

Peer-Reviewed Publications

Abu Saadeh, F, Langhe R, Galvin DM, O Toole SA, O'Donnell DM, Gleeson N, Norris LA, Procoagulant activity in gynaecological cancer patients; the effect of surgery and chemotherapy. , Thrombosis Research, 139, 2016, p135 - 141 Journal Article, 2016 DOI

Kamran MW, O'Toole F, Meghen K, Wahab AN , Abu Saadeh F, Gleeson N, Whole-body [18F]fluoro-2-deoxyglucose positron emission tomography scan as combined PET-CT staging prior to planned radical vulvectomy and inguinofemoral lymphadenectomy for squamous vulval cancer: A correlation with groin node metastasis , European Journal of Gynaecological Oncology, 35, (3), 2014, p230 - 235 Journal Article, 2014

Saadeh FA, Cheema I, McCormick P, Gleeson N, Co-Operative Radical Pelvic Surgery: A Role for the Gynecologist in Vaginal Reconstruction Using a Uterine Myoserosal Flap in Urological and Anorectal Cancer Surgery., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2014 Journal Article, 2014

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ., The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer., PLoS One. , 9, (6), 2014, pe100816- Journal Article, 2014 DOI TARA - Full Text

Abu Saadeh Feras, Wahab Nor, Gleeson N, An unusual presentation of endometriosis, British Medical Journal Case Reports , doi:10.11/bcr-2014-2, 2014 Journal Article, 2014

Wong LF, Wahab NA, Gleeson N, Appendectomy with cytoreductive surgery for ovarian and type 2 endometrial carcinoma., European journal of gynaecological oncology, 35, (2), 2014, p143-8 Journal Article, 2014

Durcan L, Gleeson N, McKiernan S, Cunnane G., A benign tumor as the apparent trigger for myopathy, J Clin Rheumatology , 20, (2), 2014, p115 - 117 Journal Article, 2014

Despierre E, Yesilyurt BT, Lambrechts S, Johnson N, Verheijen R, van der Burg M, Casado A, Rustin G, Berns E, Leunen K, Amant F, Moerman P, Lambrechts D, Vergote I, Epithelial ovarian cancer: rationale for changing the one-fits-all standard treatment regimen to subtype-specific treatment., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 24, (3), 2014, p468-77 Journal Article, 2014

McKenny M, Conroy P, Wong A, Farren M, Gleeson N, Walsh C, O'Malley C, Dowd N, A randomised prospective trial of intra-operative oesophageal Doppler-guided fluid administration in major gynaecological surgery., Anaesthesia, 68, (12), 2013, p1224-31 Journal Article, 2013

Laios A, Mohamed B, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Shiels O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, AbuSaadeh F, O'Leary J, O'Toole S., Pre-treatment of platinum resistant ovarian cancer cells with and MMP-9/MMP-2 inhibitor prior to cisplatin enhances cytotoxicity as determined by high content screening. , International Journal of Molecular Sciences., 14, (1), 2013, p2085 - 2103 Journal Article, 2013

Kamran MW, Vaughan D, Crosby D, Wahab NA, Saadeh FA, Gleeson N, Opportunistic and interventional salpingectomy in women at risk: a strategy for preventing pelvic serous cancer (PSC)., European journal of obstetrics, gynecology, and reproductive biology, 170, (1), 2013, p251-4 Journal Article, 2013

Kamran WM, Ahmed S, Wong LFA, Vaughan DA, McVey RM, Gleeson N., Skin bridge loop stoma in a gynecologic oncology unit, Gynecologic Surgery , 29, (1), 2013, p47 - 51 Journal Article, 2013

Abu Saadeh F, Norris L, O'Toole S, Gleeson N, Venous thromboembolism in ovarian cancer: Incidence, risk factors and impact on survival., European Journal of Obstetrics & Gynecology and Reproductive Biology , 170, (1), 2013, p214 - 218 Journal Article, 2013 Other

Wong LF, Gleeson N, Myomectomy: a suturing technique for the open procedure., Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 33, (2), 2013, p197-8 Journal Article, 2013

Abu Saadeh, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N, Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis risk., Thrombosis Research, 132, 2013, p627 - 634 Journal Article, 2013 DOI

Greimel E, Kristensen GB, van der Burg ME, Coronado P, Rustin G, del Rio AS, Reed NS, Nordal RR, Coens C, Vergote I, Quality of life of advanced ovarian cancer patients in the randomized phase III study comparing primary debulking surgery versus neo-adjuvant chemotherapy., Gynecologic oncology, 131, (2), 2013, p437-44 Journal Article, 2013

Carroll PA, Nolan C, Clarke R, Farrell M, Gleeson N, Boyle T, Dunne B, Daly PA, Kennedy MJ, Connolly EM, Surgical management of an Irish cohort of BRCA-mutation carriers., Breast (Edinburgh, Scotland), 20, (5), 2011, p419-23 Journal Article, 2011

Heitz F, Ognjenovic D, Harter P, Kommoss S, Ewald-Riegler N, Haberstroh M, Gomez R, Barinoff J, Traut A, du Bois A, Abdominal wall metastases in patients with ovarian cancer after laparoscopic surgery: incidence, risk factors, and complications., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 20, (1), 2010, p41-6 Journal Article, 2010

Flood K, Breathnach F, Gleeson N, An unusual presentation of a dermoid cyst., Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 30, (1), 2010, p72-3 Journal Article, 2010

Vergote I, Tropé CG, Amant F, Kristensen GB, Ehlen T, Johnson N, Verheijen RH, van der Burg ME, Lacave AJ, Panici PB, Kenter GG, Casado A, Mendiola C, Coens C, Verleye L, Stuart GC, Pecorelli S, Reed NS, Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer., The New England journal of medicine, 363, (10), 2010, p943-53 Journal Article, 2010

Walsh DJ, Sills ES, Shkrobot LV, Gleeson NC, Sheppard MN, Walsh AP, Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome., World journal of surgical oncology, 7, 2009, p46 Journal Article, 2009

Laios A, O'Toole S, Flavin R, Martin C, Kelly L, Ring M, Finn SP, Barrett C, Loda M, Gleeson N, D'Arcy T, McGuinness E, Sheils O, Sheppard B, O' Leary J, Potential role of miR-9 and miR-223 in recurrent ovarian cancer., Molecular cancer, 7, 2008, p35 Journal Article, 2008 DOI

Laios A, O'Toole SA, Flavin R, Martin C, Ring M, Gleeson N, D'Arcy T, McGuinness EP, Sheils O, Sheppard BL, O' Leary JJ, An integrative model for recurrence in ovarian cancer., Molecular cancer, 7, 2008, p8 Journal Article, 2008

Tan EK, Difficult caesarean delivery of an impacted head and neonatal skull fracture: can the morbidity be avoided?, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 27, (4), 2007, p427-8 Journal Article, 2007

Coughlan C, McAuliffe F, Bermingham N, Gleeson N, Vaginal cytology following primary hysterectomy for cervical cancer: is it useful?, Irish journal of medical science, 175, (1), 2006, p45-9 Journal Article, 2006

Breathnach F, Daly S, Griffin E, Gleeson N, Intracervical application of synthetic hydrogel sealant for preterm prelabor rupture of membranes: a case report., Journal of perinatal medicine, 33, (5), 2005, p458-60 Journal Article, 2005

Ononeze BO, Gleeson N, Turner MJ, Management of third degree perineal tear and choice of mode of delivery in subsequent pregnancies., Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 24, (2), 2004, p148-51 Journal Article, 2004

O'Toole SA, Sheppard BL, McGuinness EP, Gleeson NC, Yoneda M, Bonnar J, The MTS assay as an indicator of chemosensitivity/resistance in malignant gynaecological tumours., Cancer detection and prevention, 27, (1), 2003, p47-54 Journal Article, 2003

O'Toole SA, Sheppard Brian L, McGuinness EPJ, Gleeson NC, Misaho Yoneda, Bonnar J., Determining the response of gynaecological tumours to chemotherapy using an MTS cytotoxicity assay in combination with an explant culture technique ., British Journal of Cancer , 86, 2002 Journal Article, 2002

O'Toole SA, Sheppard BL, McGuinness E, Gleeson NC, Bonnar J, Serous papillary adenocarcinomas of the ovary display heterogeneity in their response to chemotherapy., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 11, (5), 2001, p365-71 Journal Article, 2001

O'Toole S, Sheppard B.L., Bonnar J, McGuinness E, Gleeson N., Cell Culture drug sensitivity/resistance testing of malignant gynaecological tumours., British Journal of Obstetrics and Gynaecology , 107, (6), 2000, p818 - 819 Journal Article, 2000

Hoffman MS, Fiorica JV, Gleeson NC, Roberts WS, Cavanagh D, A single institution experience with weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease., Gynecologic oncology, 60, (2), 1996, p292-4 Journal Article, 1996

Finan MA, Fiorica JV, Hoffman MS, Barton DP, Gleeson N, Roberts WS, Cavanagh D, Massive pelvic hemorrhage during gynecologic cancer surgery: "pack and go back"., Gynecologic oncology, 62, (3), 1996, p390-5 Journal Article, 1996

Gleeson NC, Hill BJ, Moscinski LC, Mark JE, Roberts WS, Hoffman MS, Fiorica JV, Cavanagh D, Urokinase plasminogen activator in ovarian cancer., European journal of gynaecological oncology, 17, (2), 1996, p110-3 Journal Article, 1996

Gleeson N, Gough F, Barry Walsh C, Turner M, Clinch J, Prendiville W. , Large loop excision of the transformation zone (LLETZ) and LLETZ conisation in the management of early squamous carcinoma of the cervix., Journal of Obstetrics and Gynaecology , 16, 1996, p525 - 528 Journal Article, 1996

Gleeson NC., Modification of the Cherney incision in gynaecological oncology surgery., British Journal of Obstetrics and Gynaecology , 102, 1995, p925 - 926 Journal Article, 1995

Finan MA, Barton DP, Fiorica JV, Hoffman MS, Roberts WS, Gleeson N, Cavanagh D, Ileus following gynecologic surgery: management with water-soluble hyperosmolar radiocontrast material., Southern medical journal, 88, (5), 1995, p539-42 Journal Article, 1995

Gleeson NC, Mark JE, Roberts WS, Hoffman MS, Fiorica JV, Cavanagh D., Predictive value of combined assays of urinary gonadotropin peptide (UGP) and CA125 in ovarian cancer., Journal of Obstetrics and Gynaecology, 15, 1995, p328 - 332 Journal Article, 1995

Gleeson NC, Buggy F, Sheppard BL, Bonnar J, The effect of tranexamic acid on measured menstrual loss and endometrial fibrinolytic enzymes in dysfunctional uterine bleeding., Acta obstetricia et gynecologica Scandinavica, 73, (3), 1994, p274-7 Journal Article, 1994

Finan MA, Fiorica JV, Roberts WS, Hoffman MS, Gleeson N, Barton DP, Cavanagh D, Artificial Dura Film for femoral vessel coverage after inguinofemoral lymphadenectomy., Gynecologic oncology, 55, (3 Pt 1), 1994, p333-5 Journal Article, 1994

Gleeson NC., Cyclical changes in endometrial tissue plasminogen activator (t-PA) and plasminogen activator inhibitor - type 1 (PAI-1) in women with normal menstruation and essential menorrhagia., American Journal of Obstetrics & Gynecology , 171, 1994, p178 - 183 Journal Article, 1994

Gleeson N, Gaffney EF, Gonsalves R, Quigley J, Bonnar J, Sarcomas of the female genital tract and pelvic soft tissues. A cluster of 14 cases in one year., Irish medical journal, 86, (6), 1994, p196-8 Journal Article, 1994

Hoffman MS, Lynch CM, Gleeson NC, Fiorica JV, Roberts WS, Cavanagh D, Colorectal anastomosis on a gynecologic oncology service., Gynecologic oncology, 55, (1), 1994, p60-5 Journal Article, 1994

Gleeson N, Baile W, Roberts WS, Hoffman M, Fiorica JV, Barton D, Cavanagh D, Surgical and psychosexual outcome following vaginal reconstruction with pelvic exenteration., European journal of gynaecological oncology, 15, (2), 1994, p89-95 Journal Article, 1994

Hoffman MS, Gleeson NC, Finan MA, Roberts WS, MS, Fiorica JV, Cavanagh D., Palliative intestinal surgery for patients with cancer of the cervix, Journal Gynecologic Surgery , 10, (2), 1994, p63 - 69 Journal Article, 1994

Gleeson NC, Baile W, Roberts WS, Hoffman MS, Fiorica JV, Finan MA, Cavanagh D, Pudendal thigh fasciocutaneous flaps for vaginal reconstruction in gynecologic oncology., Gynecologic oncology, 54, (3), 1994, p269-74 Journal Article, 1994

Gleeson N, Jordan M, Sheppard B, Bonnar J, Cyclical variation in endometrial oestrogen and progesterone receptors in women with normal menstruation and dysfunctional uterine bleeding., European journal of obstetrics, gynecology, and reproductive biology, 48, (3), 1993, p207-14 Journal Article, 1993

Gleeson NC, Finan MA, Fiorica JV, Robert WS, Hoffman MS, Wilson J, Nonmetastatic gestational trophoblastic disease. Weekly methotrexate compared with 8-day methotrexate-folinic acid., European journal of gynaecological oncology, 14, (6), 1993, p461-5 Journal Article, 1993

Gleeson N, Gonsalves R, Bonnar J, Uterine fibrinolytic enzymes in endometrial cancer., European journal of gynaecological oncology, 14, (5), 1993, p369-73 Journal Article, 1993

Barton DP, Hoffman MS, Roberts WS, Fiorica JV, Finan MA, Gleeson N, Cavanagh D, Use of local flaps in the preservation of fecal continence following resection of perianal neoplasias., International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 3, (5), 1993, p318-323 Journal Article, 1993

Finan MA, Hoffman MS, Fiorica JV, Roberts WS, Gleeson N, Barton DP, Cavanagh D, Surgical management of groin node metastases from nonvulvar gynecologic malignancies., Gynecologic oncology, 51, (2), 1993, p230-5 Journal Article, 1993

Gleeson NC, Parsons AK, Hoffman MS, Cavanagh D, Urinary ascites with pelvic urinoma presenting as ovarian neoplasm: clinical and ultrasonographic features., Obstetrics and gynecology, 82, (4 Pt 2 Suppl), 1993, p644-6 Journal Article, 1993

Gleeson NC, Gonsalves R, Bonnar J, Plasminogen activator inhibitors in endometrial adenocarcinoma., Cancer, 72, (5), 1993, p1670-2 Journal Article, 1993

Fiorica JV, Gleeson N, Roberts WS, Hoffman MS, Barton DPJ, Cavanagh D. , Venous access in gynecologic oncology patients: A comparative study of two devices. , Surgical Forum , 1993, p526 - 529 Journal Article, 1993

Norris LA, Gleeson N, Sheppard BL, Bonnar J, Whole blood platelet aggregation in moderate and severe pre-eclampsia., British journal of obstetrics and gynaecology, 100, (7), 1993, p684-8 Journal Article, 1993

Gleeson NC, Fiorica JV, Mark JE, Pinelli DM, Hoffman MS, Roberts WS, Cavanagh D, Externalized Groshong catheters and Hickman ports for central venous access in gynecologic oncology patients., Gynecologic oncology, 51, (3), 1993, p372-6 Journal Article, 1993

Hoffman MS, Gleeson N, Diebel D, Roberts WS, Fiorica JV, Cavanagh D, Colostomy closure on a gynecologic oncology service., Gynecologic oncology, 49, (3), 1993, p299-302 Journal Article, 1993

Gleeson N, Devitt M, Sheppard BL, Bonnar J, Endometrial fibrinolytic enzymes in women with normal menstruation and dysfunctional uterine bleeding., British journal of obstetrics and gynaecology, 100, (8), 1993, p768-71 Journal Article, 1993

Gleeson N, Devitt M, Buggy F, Bonnar J, Menstrual blood loss measurement with gynaeseal., The Australian & New Zealand journal of obstetrics & gynaecology, 33, (1), 1993, p79-80 Journal Article, 1993

Gleeson NC, Gormally SM, Morrison JJ, O'Regan M, Instrumental rotational delivery in primiparae., Irish medical journal, 85, (4), 1992, p139-41 Journal Article, 1992

Gleeson N, Gonsalves R, Bonnar J, The plasminogen activator urokinase and its inhibitor PAI-2 in endometrial cancer., Gynecologic oncology, 47, (1), 1992, p58-61 Journal Article, 1992

Gleeson N, Griffith A., The management of second stage of labour in primaparae with epidural analgesia., British Journal of Clinical Practice , 45, (2), 1991, p90 - 91 Journal Article, 1991

Gleeson N, Griffith A., The management of second stage of labour in primaparae with epidural analgesia. , British Journal of Clinical Practice , 45, (2), 1991, p90 - 91 Journal Article, 1991

Gleeson NC, Onwude JL, Uterine leiomyoma causing retained placenta., The British journal of clinical practice, 44, (12), 1990, p689-90 Journal Article, 1990

Sheppard BL, Boyle C, Gleeson N, Jordan M, Daly L, Bonnar J., Plasminogen activator inhibitors of the placenta and placental bed in normotensive and hypertensive pregnancy. , Placental Communications: biochemical, morphological and cellular aspects, 199, 1990, p151 - 159 Journal Article, 1990

Hoffman MS, Roberts WS, Ruffolo EH, Basal cell carcinoma of the vulva with inguinal lymph node metastases., Gynecologic oncology, 29, (1), 1988, p113-9 Journal Article, 1988

Wahab NAA, Abu Saadeh F, Lavelle M, Gleeson N, Could sentinel node mapping of groin cause abdominal wall metastases in vulval cancer? , Gynecologic & Obstetrical Investigation Journal Article,

Non-Peer-Reviewed Publications

Abu Saadeh F, O'Toole S, Gleeson N, Norris L, Peak ant-Xa levels following LMWH (tinzaparin) prophylaxis in gynaecological cancer patients post surgery, Thrombosis Research, 7th Internation Conference on Thrombosis & Hemostatis Issues in Cancer, , Bergamot Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Meeting Abstract, 2014

Noreen Gleeson, Ovarian Cancer - or is it?, Northern Obstetrics and Gynaecology Society, Letterkenny, January, 2014 Invited Talk, 2014

Noreen Gleeson, Ovarian Cancer - a new pardigm, Northern Obstetrics and Gynaecology Society, Letterkenny, March, 2014 Invited Talk, 2014

Ibrahim N, Norris L, Nikolov N, Gleeson N, Thromboelastography as a tool for detecting hypercoagulability in gynaecological cancer patients undergoing surgery, Thrombosis Research, 7th International Conference on Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Published Abstract, 2014

Ibrahim N, Norris L, O'Toole S, Gleeson N, The effect of LMWH (tinzaparin) post surgery in gynaecological patients: a study of ant-Xa activity levels., Thrombosis Research, 7th Internation Conference on Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Published Abstract, 2014

Ibrahim N, Norris L, O'Toole S, McHugh T, Gleeson N, Does extended thromboprophylaxis help reduce the incidence of venous thromboembolism in gynaecological cancer patients?, Thrombosis Research, 7th Internation Conference onal Thrombosis & Hemostatis Issues in Cancer,, Bergamo Italy, May 2014, edited by A Falanga, B. Brenner, F, Rickles , 133, (Suppl 2), Elsevier, 2014 Published Abstract, 2014

Noreen Gleeson, Peritoneal chemotherapy in ovarian cancer, All Ireland Ovarian Cancer Forum, Dublin, September, 2014 Invited Talk, 2014

Noreen Gleeson, Enhanced recovery in gyanecological oncology, Society of Pelvic Surgeons, Dusseldorf, June , 2013 Invited Talk, 2013

Noreen Gleeson, BRCA mutations - relevance for the clinical gynaecologist, Consultants' Conference in Obstetrics & Gynaecology Royal College of Physicians, , Dublin, January, 2013 Invited Talk, 2013

Noreen Gleeson, Predicting venous thrombosis in gynaecologial cancers, National VTE in cancer symposium, Dublin, April, 2013 Invited Talk, 2013

Noreen Gleeson, Ovarian cancer - the surgical pathway, Symposium on Gynaecological Cancers for Pharmaceutical Industry, Dublin, March , 2013 Invited Talk, 2013

Abu Saadeh F, Norris L, O'Toole S, Langhe R, Gleeson N., Procoagulant activity in patients with gynecological malignancies and the effect of neoadjuvant chemotherapy , Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, (Suppl 1), Elsevier, 2012 Published Abstract, 2012

Noreen Gleeson, Surgery without margins in gynecological oncology, 2nd Irish Congress of Obstetrics, Gynaecology & Perinatal Medicine, Dublin, November, 2012 Invited Talk, 2012

Noreen Gleeson, The origins of ovarian cancer - a new paradigm, Grand rounds, St. James's Hospital, Dublin, November , 2012 Invited Talk, 2012

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N, Endogenous thrombin potential as a marker for venous thrombosis in ovarian cancer., International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Published Abstract, 2012

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N., ETP as a marker for venous thromboembolism in gynaecologial cancer patients post surgery, International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Published Abstract, 2012

Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, O' Leary. J, Gleeson. N. , Why is venous thromboembolism is a common complication of ovarian cancer? , International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society. , Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Published Abstract, 2012

Abu Saadeh F, Norris L, O'Toole S, Langhe R, O'Leary JJ, Gleeson N., Does tissue factor and tissue factor pathway inhibitor over-expression play a role in the development of venous thromboembolism in ovarian cancer patients?, Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, ((Suppl 1)), Elsevier, 2012 Published Abstract, 2012

Abu Saadeh. F, Norris. L, O' Toole, Gleeson. N., Assessing the risk and mortality of venous thromboembolism in ovarian cancer., International Journal of Gynecological Cancer, 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012 Meeting Abstract, 2012

Research Expertise

Description

Major research interest include the surgical treatment of cervical, ovarian and endometrial cancer,complex and reconstructive pelvic surgery, the molecular biology cancer, prediction and prevention of thrombosis in gynaecological cancer and the role of coagulation proteases in pathogenesis of ovarian cancer. Recent projects include an investigation into the transition from endometriosis to clear cell cancer of the ovary. Noreen is a member of Gynaecological Disease Specific Subgroup - ICORG since 2005 and Co-Investigator EORTC/ICORG - Gynaecological Clinical Trials Coordinator at St James's Hospital since 2004, Gynecologic Cancer InterGroup (GCIC) since 2013.

Projects

  • Title
    • Current Clinical Trial - ICORG/GCIG - St James's Hospital
  • Summary
    • ICORG 10-12 Ovarian Cancer - ANZOG 0701 Symptom Benefit Study ICORG 11-29 Ovarian Cancer - ICON 8 ICORG 09-06 Endometrial Cancer - IMRT v 3D Radiotherapy Phase II Trial ICORG 13-07 Endometrial Cancer recurrent - AE25108-05 Cervical Cancer - SHAPE trial - P.I. for ICORG international multicentre comparative study of hysterectomy with and without parametrectomy in the surgical treatment of early cervical cancer
  • Funding Agency
    • ICORG
  • Title
    • The role of tissue factor in the transition from endometriosis to clear cell cancer.
  • Funding Agency
    • : Leo Pharma IIS/Gynaecological Cancer Fund, SJH [Co-applicant with Dr Lucy Norris]
  • Date From
    • 2013
  • Date To
    • 2015
  • Title
    • Thromboelastography as a predictor of venous thrombosis in gynaecological oncology patients undergoing surgery.
  • Funding Agency
    • Gynaecological Cancer Fund, SJH [Co-applicant with Dr Lucy Norris]
  • Date From
    • 2012
  • Date To
    • 2015
  • Title
    • Interrogation of the Onco-metabolome in ovarian cancer
  • Funding Agency
    • Royal City of Dublin Hospital Trust (Co-applicant with Dr. Sharon O'Toole]
  • Date From
    • 2013
  • Date To
    • 2016
  • Title
    • A risk model for prediction of venous thromboembolism in gynaecological cancer patients following surgery
  • Funding Agency
    • Research Board [Co-applicant with Dr Lucy Norris]
  • Date From
    • 2013
  • Date To
    • 2016
  • Title
    • Endogenous thrombin potential (ETP) and microparticle tissue factor(TF) activity as markers of venous thromboembolism in gynaecological cancer patients.
  • Funding Agency
    • Leo Pharma IIS/Gynaecological Oncology Fund SJH [Co-applicant with Dr Lucy Norris]
  • Date From
    • 2010
  • Date To
    • 2013
  • Title
    • . Study of Tissue Factor & TF Inhibitor in Ovarian Cancer.
  • Funding Agency
    • Leo Pharma IIS/Gynaecological Cancer Fund, SJH [Co-applicant with Dr Lucy Norris]
  • Date From
    • 2009
  • Date To
    • 2013
  • Title
    • CERVIVA 2: building capacity and advancing research and patient care in cervical screening and other HPV associated diseases in Ireland
  • Funding Agency
    • Health Research Board. Collaborative Applied Research Grant [P.I. Professor John O'Leary]
  • Date From
    • 2012
  • Date To
    • 2017
  • Title
    • Systems biology approaches to cervical pre-cancer and cancer SYSTEMCERV
  • Funding Agency
    • European Union 7th Framework Programme. FP7-Health HEALTH-2012.2.1.2-1 [Systems Medicine: SME driven
  • Date From
    • 2012
  • Date To
    • 2014
  • Title
    • What is the circulating tumour cell and the role of the immune editing in the metastatic cascade?
  • Funding Agency
    • Body: Health Research Board. [P.I. Professor John O'Leary]
  • Date From
    • 2012
  • Date To
    • 2017

Keywords

Gynaecology oncology; THROMBOSIS

Recognition

Representations

Lead Gynaecological Oncologist National Guidelines Committee, National Cancer Control Programme (NCCP)

Advisor/Gynaecological Cancer Expert Panel Irish Cancer Society, Institute of Obstetricians & Gynaecologists of Ireland and Ovacare Patient Support Group

Awards and Honours

The Master's Travel Prize, Coombe Women's Hospital. "Gastrostomy in gynaecological cancer surgery" - presentation to the Society of Gynecologic Oncologists. 1995

Young Oncologist award received from the American Radium Society. "Plasminogen activators and their inhibitors - markers of malignant transformation of the endometrium". April 1993

First prize for presentation to the Irish Perinatal Society. "The effects of delayed maternal effort in second stage on the foetus". 1988

Memberships

Member of the Society of Pelvic Surgeons

Member of Royal College of Obstetricians and Gynaecologists

Member of Irish Institute of Obstetricians and Gynaecologists

Member of Royal Academy of Medicine in Ireland

Member of European Society of Gynaecological Oncology

Member of International Gynaecological Cancer Society

Member of British Gynecological Cancer Society

European Organization for Research and Treatment of Cancer (EORTC)

Member of European Society of Endoscopic Surgeons