Professor Barbara Ryan
Clinical Professor, Clinical Medicine
Biography
Prof Barbara Ryan, MD, MSC, FRCPI is a Consultant Gastroenterologist at Tallaght University Hospital and Clinical Professor of Gastroenterology at TCD. She was Clinical Lead in Gastroenterology at TUH from 2007-2020. She has a special interest in pancreatobiliary disease and complex endoscopic intervention and also in inflammatory bowel disease (IBD). She had a distinguished undergraduate career including TCD Scholarship in 1990. She gained her Doctorate of Medicine (MD) degree from Trinity College in 2000 and also completed a MSc in Molecular Medicine from Trinity in 2000. She finished her higher specialist training in Gastroenterology and General Internal Medicine in Ireland in 2001 and then moved to the Medische Klinikum Rechts der Isar (MRI), Technical University of Munich, Germany, where she was a visiting Fellow in Endoscopic Ultrasound (EUS). Following this, she took up a position as a Clinical and Research Fellow at the University Hospital of Maastricht, the Netherlands, where she worked from 2001-2003. Here she honed her skills in EUS and hepatobiliary intervention and also her clinical and research interest in Inflammatory Bowel Disease (IBD). A consultant position in the UK at the Manchester Royal Infirmary followed from 2003-2004, before she took up her current consultant post at AMNCH. She was voted a 'Rising Star' in Gastroenterology by the United European Gastroenterology Federation (UEGF) in 2003 and won numerous awards for her post-graduate research, from the Irish Society of Gastroenterology, the American Gastroenterological Association (AGA) and the UEGF. She was National Specialty Director for higher specialist training in Gastroenterology in Ireland from 2012-2015. She has been on the Executive Board of the Irish Society of Gastroenterology since 2005 and is also a former Treasurer. She has been on the gastroenterology advisory panel for Colorectal Cancer for the Irish National Cancer Control Programme (NCCP). She has been actively involved in teaching (undergraduate and post-graduate) and research for the past 20 years. She has been a reviewer for numerous international journals including the Digestive Diseases and Science, Gut, Alimentary Pharmacology and Therapeutics and the European Journal of Gastroenterology and Hepatology and has delivered invited lectures in Ireland and Europe and has also frequently been on faculty at national and international meetings.
Publications and Further Research Outputs
Peer-Reviewed Publications
O'Connell, J, Ismail, M S, McCormack, M, McDonagh, P, Argue, R, Breslin, N, Crowley, V, Cullen, G, Doherty, G A, Dunne, C, Hartery, K, MacCarthy, F, McKiernan, S, Mulcahy, H, O'Connor, A, O'Morain, C, Ryan, B, Sheridan, J, Healy, M, McNamara, D, Kevans, D, P401 Association between induction vedolizumab drug levels and therapy outcome in inflammatory bowel disease, 13, (Supplement_1), 2019, ppS308-S309
O'Morain N, Kumar L, O'Carroll Lolait C, Ryan B, Infliximab induced cardiac tamponade, Irish Medical Journal, 112, (3), 2019, p902
MS Ismail, S Semenov, A O'Connor, N Breslin, B Ryan, D McNamara, COLON CAPSULE ENDOSCOPY WITH OR WITHOUT BIOMARKERS AS A VIABLE ALTERNATIVE TO COLONOSCOPY IN UNSELECTED PATIENTS WITH LOWER GI SYMPTOMS: RESULTS OF A PILOT STUDY, Endoscopy, ESGE Days, Prague, April 2019, 51, (4), 2019, ppS161-
Fennessy, A M, Hanna, C, Breslin, N, Mc Namara, D, Anwar, S, O'Connor, A, Ryan, B M, P581 Complementary and alternative therapies for inflammatory bowel disease, 13, (Supplement_1), 2019, ppS405-S406
Delaney S, O'Connor G, Reardon W, Murphy SJX, Tierney S, Ryan BM, Delaney H, Doherty CP, Guiney M, Brennan P, Tobin WO, McCabe DJH., Extracranial and Intracranial Vasculopathy With "Moyamoya Phenomenon" in Association With Alagille Syndrome., Frontiers in neurology, 9, 2019, p1194
M Syafiq Ismail, N O'Morain, B Ryan, D McNamara, BALLOON SPHINCTEROPLASTY IS A SAFE AND RELIABLE METHOD TO ACHIEVE BILIARY CLEARANCE IN AN AT RISK CHOEDOCHOLITHIASIS COHORT, Endoscopy, ESGE Days, Prague, April 2019, 51, (4), 2019, ppS234-
Mohan LJ, Daly JS, Ryan BM, Ramtoola Z., The future of nanomedicine in optimising the treatment of inflammatory bowel disease., Scandinavian journal of gastroenterology, 2019, p1-9
S Semenov, M Syafiq Ismail, A O'Connor, N Breslin, B Ryan, D McNamara, POSITIVE IMPACT OF SWITCHING FROM BSG TO ESGE POST POLYPECTOMY GUIDELINES ON A COLONOSCOPY SURVEILLANCE WAITING LIST, Endoscopy, ESGE Days, Prague, April 2019, 51, (4), 2019, ppS215-
Parihar, Vikrant, Sopheno-Falco, Julia, Maheshwari, Pardeep, O'Moran, Neil, Graziadei, Vivien, O'Grady Walshe, Aishling, O'Dwyer, Orla, Kumar, Lakshman, Fennessy, Sean, Breslin, Niall, Ryan, Barbara M., McNamara, Deirdre, Adherence to European Polypectomy Guidelines: Retrospective Experience from a Tertiary Irish Hospital, Gastrointestinal Tumors, 5, (3-4), 2019, p82-89
Callaghan GM, Kelleher FC, Ridgway PF, Crowther S, Alakkari A, Ryan BM, A Case of Primary Gastric Melanoma Exhibiting a Rare BRAF V600R Mutation., European journal of case reports in internal medicine, 2018
O'Morain, N, Farrell, G, Hanly, M, Veerappan, S, McNamara, D, Breslin, N, O'Morain, C, Healy, M, Ryan, B, P463 Long-term effects of anti-TNF therapy on bone metabolism, 12, (supplement_1), 2018, ppS339-S339
Judge, C, McGettigan, N, Ryan, T, Hazel, K, Singh, P, Parihar, V, Stack, R, O'Connor, A, Dunne, C, Cullen, G, Egan, L, Harewood, G, MacCarthy, F, McKiernan, S, Mulcahy, H, Murray, F, Patchett, S, Sheridan, J, Trevian, D, Breslin, N, Farrell, R, Keohane, J, Kelly, O, McNamara, D, Ryan, B, Smyth, C, O'Morain, C, Sengupta, S, Slattery, E, Doherty, G, Kevans, D, O'Toole, A, P597 Effectiveness and safety of vedolizumab therapy in an ulcerative colitis cohort with significant prior anti-TNF exposure, 12, (supplement_1), 2018, ppS410-S411
O'Connell J, Rowan C, Stack R, Harkin G, Parihar V, Chan G, Breslin N, Cullen G, Dunne C, Egan L, Harewood G, Leyden J, MacCarthy F, MacMathuna P, Mahmud N, McKiernan S, McNamara D, Mulcahy H, Murray F, O'Connor A, O'Toole A, Patchett S, Ryan B, Sheridan J, Slattery E, Doherty G, Kevans D., Golimumab effectiveness and safety in clinical practice for moderately active ulcerative colitis., European Journal of Gastroenterology, 30, (9), 2018, p1019 - 1026
O'Morain N, O'Gorman S, McNamara D & Ryan B., Patients' attitudes toward treatment withdrawal in inflammatory bowel disease., Scandinavian Journal of Gastroenterology, 53, (10-11), 2018, p1428-
Venkatachalapathy SV, Bekkali N, Pereira S, Johnson G, Oppong K, Nayar M, Leeds J, Paranandi B, Penman I, Carroll N, Godfrey E, James M, Aithal G, McKay C, Devlin J, Wong T, Makin A, Ryan B, Huggett M., Multicenter experience from the UK and Ireland of use of lumen-apposing metal stent for transluminal drainage of pancreatic fluid collections., Endoscopy international open, 6, (3), 2018, pE259-E265
Christopher, B, Altamimi, K, Campbell, N, Rynne-Lyons, R, Alakkari, A, O'Connor, A, McNamara, D, Breslin, N, Ryan, B, P412 White cell count (WCC) and mean corpuscular volume (MCV) as surrogate markers for thiopurine monitoring in inflammatory bowel disease (IBD) treatment: A single-centre experience, 12, (supplement_1), 2018, ppS312-S313
O'Morain, Neil, Shahin, Ammar, Ryan, Barbara, McNamara, Deirdre, Mo1690 CHROMOENDOSCOPY POST-EMR REDUCES THE RATE OF INCOMPLETE POLYP RESECTION, 87, (6), 2018, ppAB480
Ní Chonchubhair HM, Bashir Y, Dobson M, Ryan BM, Duggan SN, Conlon KC, The prevalence of small intestinal bacterial overgrowth in non-surgical patients with chronic pancreatitis and pancreatic exocrine insufficiency (PEI)., Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2018
Stack, R, O'Brien, C, Nuzum, T, Kumar, L, Maheshwari, P, Breslin, N, Ryan, B, O'Connor, A, Murphy, I, Mc Namara, D, P259 Measures of predicting inflammatory and fibrotic strictures in Crohn"s disease patients using magnetic resonance, 12, (supplement_1), 2018, ppS231-S232
Alakkari A, Stack R, Parihar V, Crowther S, Ryan B, Acute granulomatous hepatitis in an immunosuppressed patient secondary to Q fever, Quarterly Journal Of Medicine, (May 26 [Epub]), 2017, pdoi: 10.1093/qjmed/hcx 105
Dominguez Castro P, Harkin G, Hussey M, Christopher B, Kiat C, Chin JL, Trimble V, McNamara D, MacMathuna P, Egan B, Ryan B, Kevans D, Farrell R, Byrnes V, Mahmud N, McManus R. , Changes in Presentation of Celiac Disease in Ireland From the 1960s to 2015, Clinical Gastroenterology and Hepatology, 15, (1), 2017, p864 - 871
Rowan, C.R., Alakkari, A., Moran, C., O'Connell, J., Cullen, G., Mulcahy, H., O'Morain, C., McNamara, D., Leyden, J., MacMathuna, P., O'Toole, A., Patchett, S., McKiernan, S., Kevans, D., Doherty, G.A., Ryan, B., P594 Ustekinumab treatment effectiveness in clinical practice " a multicentre retrospective review of long-term outcomes in Crohn's disease, 11, (suppl_1), 2017, ppS383-S384
Tighe D, Smith S, O'Connor A, Breslin N, Ryan B, McNamara D , Positive relationship between infliximab and adalimumab trough levels at completion of induction therapy with clinical response rates, at a tertiary referral center, JGH Open, 1, (1), 2017, p4 - 10
Castro, Patricia Dominguez, Harkin, Grace, Hussey, Mary, Christopher, Brian, Kiat, Clifford, Chin, Jun Liong, McNamara, Deirdre, MacMathuna, Padraic, Egan, Brian J., Ryan, Barbara, Kevans, David, Farrell, Richard, Byrnes, Valerie, McManus, Ross, Pattern of Thyroid Disease Presentation in a Cohort of Celiac Patients Diagnosed from 1960-2015, 152, (5), 2017, ppS484
Parihar V, Ridgway PF, Conlon, KC, Huggett M, Ryan BM, 7. The Role of Endoscopic Intervention in the Management of Inflammatory Pancreatic Fluid Collections. , European Journal of Gastroenterology and Hepatology, Apr;29, (4), 2017, p371 - 379
Tighe, D., Breslin, N., Ryan, B., McNamara, D., P602 Clinical/biochemical predictors of response to anti-TNFa therapies in a tertiary referral centre, 11, (suppl_1), 2017, ppS386-S387
Stack R, McLoughlin J, Gillis A, Ryan BM, Post-ERCP Emphysematous cholecystitis in a young woman: A rare and potentially fatal complication, Case Reports in Gastrointestinal Medicine, (March), 2017, pdoi: 10.1155/2017/1971457
Parihar V, Stack R. Alakkari A. Breslin N, Ryan B, Crowther S, McNamara D., Clinical Outcome of Patients with Raised Intraepithelial Lymphocytes with Normal Villous Architecture on Duodenal Biopsy, Digestion, 95, 2017, p288 - 292
Stack, R., Ridgeway, L., Moran, N., Breslin, N., Ryan, B., Mc Namara, D., P276 A snap-shot review of small bowel capsule endoscopy in the setting of inflammatory bowel disease, 11, (suppl_1), 2017, ppS218-S218
O'Connell, J., Rowan, C., Chan, G., Harkin, G., Parihar, V., Layden, J., Patchett, S., Stack, R., MacMathuna, P., O'Toole, A., Ryan, B., MacCarthy, F., McKiernan, S., Doherty, G., Eagan, L., Kevans, D., P403 Golimumab therapy for ulcerative colitis " an Irish multicentre experience, 11, (suppl_1), 2017, ppS282-S282
Castro, Patricia Dominguez, Harkin, Grace, Hussey, Mary, Christopher, Brian, Kiat, Clifford, Chin, Jun Liong, McNamara, Deirdre, MacMathuna, Padraic, Egan, Brian J., Ryan, Barbara, Kevans, David, Farrell, Richard, Byrnes, Valerie, McManus, Ross, Co-Existence of Celiac Disease and other Immune-Mediated Conditions in Celiac Patients, 152, (5), 2017, ppS483-S484
Mohamed, G., Crotty, P., McNamara, D., Breslin, N., Ryan, B.M., P208 Long term follow up of lymphocytic colitis patients, 11, (suppl_1), 2017, ppS181-S182
Tighe D, Hall B, Jeyarajah SK, Smith S, Breslin N, Ryan B, McNamara D., One-Year Clinical Outcomes in an IBD Cohort Who Have Previously Had Anti-TNFa Trough and Antibody Levels Assessed, Inflammatory Bowel Disease, 23, (7), 2017, p1154 - 1159
Memba R and Duggan SN and Ni Chonchubhair HM and Griffin OM and Bashir Y and O'Connor DB and Murphy A and McMahon J and Volcov Y and Ryan BM and Conlon KC, The potential role of gut microbiota in pancreatic disease: A systematic review., Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2017
Ní Chonchubhair HM, O Shea B,, Kavanagh DO, Ryan BM, Duggan SN, Conlon KC, 2. Chronic pancreatitis in primary and hospital-based care in Ireland: The management of an orphan disease, Journal of the Pancreas, 17, (4), 2016, p216 - 222
Hussey M, Mc Garrigle R, Kennedy U, Holleran G, Kevans D, Ryan B, Breslin N, Mahmud N, McNamara D, Long-term assessment of clinical response to adalimumab therapy in refractory ulcerative colitis., European journal of gastroenterology & hepatology, 28, (2), 2016, p217-21
Stack R, Parihar V, Ryan B, Alakkari A, CMV pneumonitis in an immunosuppressed Crohn's disease patient., QJM : monthly journal of the Association of Physicians, 2016
Ryan BM, Venkatachalapathy SV, Huggett MT, Safety of lumen-apposing metal stents (LAMS) for pancreatic fluid collection drainage, Gut, Dec 16 , (EPub ahead of print), 2016
Veerappan SG, Healy M, Walsh B, O'Morain CA, Daly JS, Ryan BM, A 1-year prospective study of the effect of infliximab on bone metabolism in inflammatory bowel disease patients., European journal of gastroenterology & hepatology, 2016
Venkatachalapathy, Suresh Vasan, Makin, Alistair, Pereira, Stephen P., Johnson, Gavin J., Bekkali, Noor, Penman, Ian, Oppong, Kofi W., Nayar, Manu K., Carroll, Nicholas R., Godfrey, Edmund M., Ryan, Barbara M., Parihar, Vikrant, Huggett, Matthew T., The first multicentre experience from the UK and Ireland of the use of the hot AXIOS system for transluminal drainage of pancreatic fluid collections, 16, (3), 2016, ppS105
Venkatachalapathy, SV, Makin, A, Pereira, SP, Johnson, GJ, Bekkali, N, Penman, I, Oppong, KW, Nayar, MK, Carroll, NR, Godfrey, EM, Ryan, BM, Parihar, V, McKay, CJ, Huggett, MT, OC-073"The First Multicentre Experience from The UK and Ireland of the Use of the Hot Axios System for Transluminal Drainage of Pancreatic Fluid Collections, 65, (Suppl 1), 2016, ppA44.1-A44
V Parihar, R Stack, A Alakkiri, BM Ryan, A case of incidental diagnosis of renal cell carcinoma by endoscopic ultrasound, Journal of gastric disorders and therapy, 2, (4), 2016, p125 - 126
Hussey, Mary, McGarrigle, Robert, Kennedy, Una, Holleran, Grainne, Kevans, David, Breslin, Niall, Ryan, Barbara, Mahmud, Nasir, McNamara, Deirdre, Sa1246 Long Term Assessment of Clinical Response to Adalimumab Therapy in Refractory Ulcerative Colitis, 148, (4), 2015, ppS-268
Veerappan S.G, Healy M, Walsh B.J, Oâ Morain C.A, Daly J.S, Ryan B.M, Adalimumab Therapy Has a Beneficial Effect on Bone Metabolism in Patients with Crohnâ s Disease, Digestive Diseases and Sciences, 60, (7), 2015, p2119 - 2129
Maung SW, Desmond R, McHugh J, Ryan B, Neary P, Jeffers M, Enright H, A coincidence or a rare occurrence? A case of plasmablastic lymphoma of the small intestines following infliximab treatment for Crohn's disease., Annals of hematology, 2015
Hall B, Holleran G, Chin JL, Smith S, Ryan B, Mahmud N, McNamara D, A prospective 52 week mucosal healing assessment of small bowel Crohn's disease as detected by capsule endoscopy., Journal of Crohn's & colitis, 8, (12), 2014, p1601-9
Alakkari, A, Gammell, Y, O'Connor, H, McNamara, D, Breslin, N, Ryan, B, AUDIT OF THE APPROPRIATENESS OF HEPATOMA SURVEILLANCE IN A COHORT OF PATIENTS ATTENDING A DEDICATED HAEMOCHROMATOSIS CLINIC, 62, (Suppl 2), 2013, ppA28.3-A29
O'Donnell S, Crotty P.L, O'Sullivan M, Breslin N, O'Connor H.J, O'Morain C.A, Ryan B.M, Isolated active ileitis: Is it a mild subtype of Crohn's disease?, Inflammatory Bowel Diseases, 19, (9), 2013, p1815 - 1822
Alakkari, A, Leen, R, Breslin, N, Ryan, B, DIAGNOSTIC YIELD OF FOCUSED ENDOSCOPIC ULTRASOUND EXAMINATION OF THE BILIARY TREE IN A TERTIARY REFERRAL CENTRE, 62, (Suppl 2), 2013, ppA28.2-A28
Sandborn WJ, Feagan BG, Rutgeerts P, Hanauer S, Colombel JF, Sands BE, Lukas M, Fedorak RN, Lee S, Bressler B, Fox I, Rosario M, Sankoh S, Xu J, GEMINI 2 Study Group, Vedolizumab as induction and maintenance therapy for Crohn's disease., The New England journal of medicine, 2013
O'Connor A, Taneike I, Nami A, Fitzgerald N, Ryan B, Breslin N, O'Connor H, McNamara D, Murphy P, O'Morain C, Helicobacter pylori resistance rates for levofloxacin, tetracycline and rifabutin among Irish isolates at a reference centre., Irish journal of medical science, 182, (4), 2013, p693-5
Burska, S, Ryan, B, MUSCULOSKELETAL SYMPTOMS AMONGST ENDOSCOPISTS, 62, (Suppl 2), 2013, ppA45.1-A45
O'Donnell S, O'Sullivan M, O'Morain C.A, Ryan B.M, The clinical significance of antimicrobial serologic responses within an Irish Crohn's disease population, European Journal of Gastroenterology and Hepatology, 25, (12), 2013, p1464 - 1469
Feagan BG, Rutgeerts P, Sands BE, Hanauer S, Colombel JF, Sandborn WJ, Van Assche G, Axler J, Kim HJ, Danese S, Fox I, Milch C, Sankoh S, Wyant T, GEMINI 1 Study Group, Vedolizumab as induction and maintenance therapy for ulcerative colitis., The New England journal of medicine, 2013
O'Connor, Anthony, Alakkari, Alaa, Ryan, Barbara M., Breslin, Niall, McNamara, Deirdre, O'Connor, Humphrey J., O'Morain, Colm A., Mo1580 Age, Smoking, Male Gender and Regular Aspirin use Predict Premalignant Conditions of the Stomach in a Low Gastric Cancer Prevalence Cohort, 142, (5), 2012, ppS-633
Thornhill J.A, Long R.M, Neary P, O'Connor H.J, Ryan B, Fraser I, The pitfalls of treating anorectal conditions after radiotherapy for prostate cancer., Irish medical journal, 105, (3), 2012, p91 - 93
Keane R, O'Connor A, Ryan B, Breslin N, O'Connor H, Qasim A, O'Morain C, Inappropriate colonoscopic surveillance of hyperplastic polyps, Irish Medical Journal, 104, (7), 2011
O'Donnell, Sarah, O'Sullivan, Maria, Breslin, Niall, O'Connor, Humphrey J., O'Morain, Colm A., Crotty, Paul L., Ryan, Barbara M., Isolated Active Ileitis: Serological and Genetic Profile, 140, (5), 2011, ppS-1
Qasim A, Ullah N, Crotty P, Swan N, Breslin N, Ryan B, Torreggiani W, Eguare E, Neary P, O'Connor H, O'Morain C, A changing trend in the management of patients with newly diagnosed Crohn's disease, Ir J Med Sci. , 180, (3), 2011, p643 - 647
O'Donnell S, Kelly O.B, Breslin N, Ryan B.M, O'Connor H.J, Swan N, O'Morain C.A, Eosinophilic oesophagitis: An Irish experience, European Journal of Gastroenterology and Hepatology, 23, (12), 2011, p1116 - 1121
O'Donnell S, Murphy S, Anwar MM, O'Sullivan M, Breslin N, O'Connor HJ, Ryan BM, O'Morain CA, Safety of infliximab in 10 years of clinical practice., Eur J Gastroenterol Hepatol, 23, (7), 2011, p603 - 606
Shuhaibar M, Walsh C, Lindsay F, Lee N, Walsh P, O'Gorman P, Boran G, McLoughlin R, Qasim A, Breslin N, Ryan B, O'Connor H, O'Morain C, A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers., Irish journal of medical science, 180, (1), 2011, p103-8
Veerappan S.G, O'Morain C.A, Daly J.S, Ryan B.M, The effects of antitumour necrosis factor-α on bone metabolism in inflammatory bowel disease, Alimentary Pharmacology and Therapeutics, 33, (12), 2011, p1261 - 1272
O'connor A, Taneike I, Nami A, Fitzgerald N, Murphy P, Ryan B, O'connor H, Qasim A, Breslin N, O'moráin C, Helicobacter pylori resistance to metronidazole and clarithromycin in Ireland., European journal of gastroenterology & hepatology, 22, (9), 2010, p1123-7
Abbasakoor NO, Kavanagh DO, Moran DC, Ryan B, Neary PC, Midgut pain due to an intussuscepting terminal ileal lipoma: a case report., Journal of Medical Case Reports, 4, 2010, p51
Teo M, Ryan B, Swan N, McDermott RS, A Case of Metastatic Renal Cell Cancer Presenting as Jaundice., World journal of oncology, 2010
O'Connor A, Keane RA, Egan B, Lee N, O'Connor H, Qasim A, Ryan B, Breslin N, McNamara D, O'Morain C, Adherence to colorectal polyp surveillance guidelines: is there scope to increase the opportunities for screening?, European Journal of Cancer Prevention : the official journal of the European Cancer Prevention Organisation (ECP), 20, (1), 2010, p40 - 45
Qasim A, Ryan B, Breslin N, O'Morain C, Gastric retention and wireless capsule endoscopy in adults: a modified technique for direct duodenal deployment., Gut, 59, (7), 2010, p1004-5
O'Donnell, Sarah, Crotty, Paul, Breslin, Niall, Swan, Niall, O'Morain, Colm A., Ryan, Barbara M., M1106 The Serological Profile of Isolated Active Ileitis, 136, (5), 2009, ppA-351
Murphy G, Thornton J, McManus R, Swan N, Ryan B, Hughes D, O'Morain C, O'Sullivan M, Association of gastric disease with polymorphisms in the inflammatory related genes IL-1B, IL-1RN, IL-10, TNF and TLR4 , European Journal of Gastroenterology and Hepatology, 21, (6), 2009, p630-635
O'Donnell, Sarah, O'Sullivan, Maria, Breslin, Niall, Qasim, Asghar, O'Morain, Colm A., Ryan, Barbara M., M1102 ANCA, ASCA, Anti-OmpC and Anti-Cbir Antibodies Within An Irish Crohns Disease Cohort, 136, (5), 2009, ppA-350
O'Donnell S, Qasim A, Ryan B.M, O'Connor H.J, Breslin N, O'Morain C.A, The role of capsule endoscopy in small bowel Crohn's disease, Journal of Crohn's and Colitis, 3, (4), 2009, p282 - 286
O'Connor, Anthony, Ryan, Barbara M., O'Connor, Humphrey J., O'Morain, Colm A., Qasim, Asghar, Breslin, Niall, Colonoscopy in Adults Younger Than 30 Years: A Blunt Instrument?, 69, (5), 2009, ppAB317
Veerpan SG, Kennedy M, O'Morain CA, Ryan BM, Retinal vein thrombosis following infliximab treatment for severe left-sided ulcerative colitis, European Journal of Gastroenterolgy and Hepatology, 20, (6), 2008, p588 - 589
Holmes, Kate, Egan, Brian J., Heetun, Zaid S., Breslin, Niall, Ryan, Barbara M., Swan, Niall, O'Connor, Humphrey J., O'Morain, Colm A., W1882 Identification of Smoking As a Risk Factor for Gastric Intestinal Metaplasia, 134, (4), 2008, ppA-725
Veerappan, Sundaram G., Healy, Martin, Walsh, J Bernard, Kennedy, Mary, O'Morain, Colm A., Ryan, Barbara M., Daly, Jacqueline, T1239 Infliximab in Inflammatory Bowel Disease: `Can We Heal Two Disease with One Drug?", 134, (4), 2008, ppA-513
Sarwar S, Anwar MM, Ryan B, O'Morain C., Colonoscopy completion rates--are we prepared for a national screening programme?, Irish Medicial Journal, Oct;100 , (9), 2007, p585-7.
Wolters FL, Joling C, Russel MG, Sijbrandij J, De Bruin M, Odes S, Riis L, Munkholm P, Bodini P, Ryan B, O'Morain C, Mouzas IA, Tsianos E, Vermeire S, Monteiro E, Limonard C, Vatn M, Fornaciari G, Rodriguez D, Groot W, Moum B, Stockbrügger RW, Treatment inferred disease severity in Crohn's disease: evidence for a European gradient of disease course., Scandinavian journal of gastroenterology, 42, (3), 2007, p333-44
Veerappan, SG, O'Morain, CA, Ryan, BM, Prevalence and Evolution of Hypertransaminasemia in the Newly Diagnosed Coeliac Patients: An Irish Experience in a Dublin Hospital, 38, (11), 2006
Veerappan, SG, Breslin, N, O'Morain, CA, Ryan, BM, Investigations of Asymptomatic Patients with Abnormal Liver Function Tests (LFT's) in the Outpatient Setting. Experience and Cost Analysis in the Real World, 38, (11), 2006
Shiel, E, McLoughlin, R, Ryan, B, O'Morain, CA, Stool DNA Testing " Not Quite There Yet?, 38, (11), 2006
Anwar, MM, Sarwar, S, Egan, BJ, Veerapan, S, Ryan, B, Breslin, N, O'Morain, C, Infliximab in Patients with Moderate to Severe Ulcerative Colitis with a Failed Response to Medical Therapy, 38, (11), 2006
Sarwar, S, Anwar, M, Ryan, B, O'Morain, C, Standards of colonoscopy in tallaght hospital; need for beyond the caecum, 37, (12), 2006
Egan, BJ, Sarwar, S, Anwar, M, O'Morain, C, Ryan, B, Alpha 1 Anti Trypsin Levels in Asymptomatic Patients with Abnormal Liver Function Tests, 38, (11), 2006
Sarwar, S, Anwar, MM, Egan, B, Ryan, B, Breslin, N, O'Morain, C, Changing Prevalence of Helicobacter pylori Infection in Elderly Dyspeptic Patients, 38, (11), 2006
Chan, VO, Veerappan, SG, Thornton, O, Dobson, M, Ryan, B, Breslin, N, O'Connor, H, Crotty, P, O'Morain, C, Prevalence of Helicobacter pylori: An Irish Experience in a Dublin Associated Teaching Hospital over a Six Year Period, 38, (11), 2006
Anwar, M, O'Sullivan, M, Sarwar, S, Ryan, B, Breslin, N, O'Connor, H, O'Morain, C, Adalimumab in the Management of Crohn's Disease (CD) Patients with a Loss of Response to Infliximab, 38, (11), 2006
Chan, V, O'Morain, C, O'Connor, H, Ryan, B, Distribution of polyps and cancer in the colon, 37, (05), 2005
McLoughlin, RM, Shiel, E, Sebastian, SS, Ryan, B, O'Connor, HJ, O'Morain, C, A new marker for colorectal cancer, 37, (05), 2005
De Vries G.J, Ryan B.M, De BiÚvre M, Driessen A, Stockbrugger R.W, Koek G.H, Cirrhosis related chylous ascites successfully treated with TIPS, European Journal of Gastroenterology and Hepatology, 17, (4), 2005, p463 - 466
Ryan B.M, Russel M.G.V.M, Schurgers L, Wichers M, Sijbrandij J, Stockbrugger R.W, Schoon E, Effect of antitumour necrosis factor-α therapy on bone turnover in patients with active Crohn's disease: A prospective study, Alimentary Pharmacology and Therapeutics, 20, (8), 2004, p851 - 857
Ryan JM, Ryan BM, Smith TP, Antibiotic prophylaxis in interventional radiology., 2004
Ryan, J.M., Ryan, B.M., Smith, T.P., Antibiotic prophylaxis in interventional radiology, Journal of Vascular and Interventional Radiology, 15, (6), 2004, p547-556
Ryan BM, Romberg M, Wolters F, Stockbrugger RW, Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction., European journal of gastroenterology & hepatology, 2004
Ryan BM, Stockbrugger RW, Ryan JM, A pathophysiologic, gastroenterologic, and radiologic approach to the management of gastric varices., Gastroenterology, 2004
Lo G.-H, Lai K.-H, Ryan B.M, Stockbrugger R.W, Ryan J.M, Should GOV1 be treated as for esophageal varices? [2] (multiple letters), Gastroenterology, 127, (3), 2004, p1014 - 1015
Ryan B.M, Russel M.G.V.M, Langholz E, Stockbrugger R.W, Aminosalicylates and colorectal cancer in IBD: A not-so bitter pill to swallow, American Journal of Gastroenterology, 98, (8), 2003, p1682 - 1687
Russel M.G.V.M, Ryan B.M, Dagnelie P.C, De Rooij M, Sijbrandij J, Feleus A, Hesselink M, Muris J.W, Stockbrugger R, Insurance problems among inflammatory bowel disease patients: Results of a Dutch population based study, Gut, 52, (3), 2003, p358 - 362
F. Khosa, J. G. McNulty, N. Hickey, P. O'Brien, A. Tobin, N. Noonan, B. Ryan, P. W. Keeling, D. P. Kelleher and G. S. McDonald, Transvenous liver biopsy via the femoral vein, Clinical radiology, 58, (6), 2003, p487-91
Ryan B.M, Stockbrugger R.W, Ryan J.M, Tripathi D, Therapondos G, Hayes P.C, Redhead D.N, Tips for gastric varices [7] (multiple letters), Gut, 52, (5), 2003, p772-
Ryan BM, Stockbrugger RW, Ryan JM., TIPS for gastric varices. , Gut, 52, 2003, p772 - 773
Ryan BM, Lefort L, McManus R, Daly J, Keeling PW, Weir DG, Kelleher D, A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up, Gut, 52, (1), 2003, p101-108
Wolters F, Ryan B, Beets-Tan R, Dejong C, Delayed massive hemobilia after biliary stenting, Endoscopy, 35, (11), 2003, p976 - 977
Daly, Jacqueline, McManus, Ross, Hagan, Richard, Ryan, Anthony, Ryan, Barbara, Ang, Yeng, Farrell, Richard, Weir, Donald, Kelleher, Dermot, The TNF region in celiac disease, 124, (4), 2003, ppA658
Ryan, Barbara M., Russel, Maurice G., Schurgers, Leon, Wolters, Frank, Stockbrugger, Reinhold W., Schoon, Erik, Infliximab therapy has a benefical effect on bone formation but not bone resorption in patients with active Crohn's disease, 124, (4), 2003, ppA214
B. M. Ryan, A. M. Molloy, R. McManus, Q. Arfin, D. Kelleher, J. M. Scott and D. G. Weir, The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression, International journal of gastrointestinal cancer, 30, (3), 2001, p105-111
Ryan B.M, Murphy G, O'Morain C.A, Host cytokine responses to Helicobacter pylori: An important determinant of clinical outcome, Irish Journal of Medical Science, 170, (2), 2001, p90 - 91
B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British Journal of Cancer, 85, (10), 2001, p1499-1503
Ryan B.M, Weir D.G, Relevance of folate metabolism in the pathogenesis of colorectal cancer, Journal of Laboratory and Clinical Medicine, 138, (3), 2001, p164 - 176
Daly JS, McManus R, Whelan R, Ryan B, Ang YS, Farrell R, Hagan R, Weir DG, Kelleher D, Analysis of single nucleotide polymorphisms (SNPS) in the tumour necrosis factor (TNF) gene in celiac disease, GASTROENTEROLOGY, 118, (4), 2000, ppA365 - A365
B. M. Ryan and D. Kelleher, Refractory celiac disease, Gastroenterology, 119, (1), 2000, p243-51
Ryan BM, McManus R, Daly JS, Keeling NWP, Weir DG, Lefort F, Kelleher D, Serum mutant K-ras in the colorectal adenoma-to-carcinoma sequence. Implications for diagnosis, postoperative follow-up, and early detection of recurrent disease, Annals of the New York Academy of Sciences, 906, 2000, p29-30
Ryan, Barbara Mary, McManus, Ross, Daly, Jacqueline S., Carton, Eleanor, Reynolds, John V., Kelleher, Dermot, A polymorphism in p73, a novel p53-homologue, confers protection against the development of esophageal cancer, 118, (4), 2000, ppA704
B. M. Ryan, R. O. McManus, J. S. Daly, P. W. Keeling, D. G. Weir, F. Lefort and D. Kelleher, Serum mutant K-ras in the colorectal adenoma-to-carcinoma sequence. Implications for diagnosis, postoperative follow-up, and early detection of recurrent disease, Annals of the New York Academy of Sciences, 906, 2000, p29-30
Ryan, Barbara Mary, Molloy, Anne, McManus, Ross, Daly, Jacqueline S., Scott, John M., Kelleher, Dermot, Weir, Donald G., Polymorphism and loss of heterozygosity (LOH) of themethylenetetrahydrofolate (MTHFR) enzyme is associated with the development of colorectal cancer, 118, (4), 2000, ppA703
Ryan, Barbara M., McManus, Ross, Daly, Jacqueline S., LeFort, Francois, Keeling, Napoleon, Weir, Donald G., Kelleher, Dermot, Post-operative serum mutant k-ras- a sensitive marker of disease recurrence in patients with colorectal cancer, 118, (4), 2000, ppA514
Ryan, Barbara Mary, Daly, Jacqueline S., McManus, Ross, Carton, Eleanor, Keeling, Napoleon, Kelleher, Dermot, Impact of polymorphisms in the TNF alpha promoter region on outcome in esophageal cancer, 118, (4), 2000, ppA37
B. M. Ryan, G. S. McDonald, R. Pilkington and D. Kelleher, The development of hepatic granulomas following interferon-alpha2b therapy for chronic hepatitis C infection, European journal of gastroenterology & hepatology, 10, (4), 1998, p349-51
Ryan, B.M., Brennan, E.G., O'Hare, N., McDermott, R., Keeling, P.W.N., Byrne, P.J., Post-prandial EGG dysrhythmia in NUD is not predictive of altered gastric emptying and is more common in HP(+) than HP(") patients: (Preliminary results of on-going study), 114, 1998, ppA829
Ryan, BM, Byrne, PJ, Quill, R, Keeling, PWN, Pudendal nerve neuropathies are extremely common in chronic constipation and faecal incontinence, 114, 1998, ppA829
Ryan J.M, Kelsey P, Ryan B.M, Mueller P.R, Alendronate-induced esophagitis: Case report of a recently recognized form of severe esophagitis with esophageal stricture - Radiographic features, Radiology, 206, (2), 1998, p389 - 391
Ryan, BM, Byrne, PJ, McKiernan, S, Quill, R, Keeling, PWN, Detailed symptom evaluation in chronic constipation can help identify those with different pathophysiological disorders of defaecation and hence direct further clinical investigation, 114, 1998, ppA828-A829
Research Expertise
Description
I have been involved in basic and translational research for all of my professional career and there are a number of strands to my research and these can be consolidated into four main areas. 1. Inflammatory Bowel Disease 2. Pancreatic Disease and Interventional Pancreatobiliary Endoscopy. 3. Biomarkers in GI disease 4. Coeliac disease. I also have a major clinical interest in functional digestive conditions including IBS, Functional Dyspepsia and Functional Biliary Sphincter Disorder (formerly Sphincter of Oddi Dysfunction). ARecognition
Representations
National Specialty Director for Higher Specialist Training in Gastroenterology in Ireland
Member of Gastroenterology advisory panel for the Irish National Cancer Control Programme (NCCP).
NIHR (National Institute for Health Research) in the UK
European Society of Gastrointestinal Endoscopy; Irish Representative
National Endoscopy Training Committee, board member
Irish Society of Gastroenterology - Member of Board and Scientific Organising Committee
Irish Society of Gastroenterology Honorary Treasurer
Awards and Honours
Trinity College Scholarship in Medicine 1990
The Henry Hutchinson Award , TCD
The Walter G. Smith Prize in Pharmacology, TCD
The Upjohn Prize in Pharmacology, TCD
The Upjohn Essay Prize in Pharmacology
Meath Hospital Prize in Clinical Medicine and Surgery.
The Fitzpatrick Scholarship for first place in class TCD
The G.B. Hutchinson Bequest for highest overall results, TCD
Professor's Prize in Surgery, TCD
Professor's Prize in Obstetrics and Gynaecology, TCD
Professor's Prize in Paediatrics, TCD
The Reuben-Harvey Prize, TCD
The Arthur Ball Prize for highest mark in Surgery, TCD
The David Gault Memorial Prize , Rotunda Hospital
Adelaide Hospital Prize.
Irish Society of Gastroenterology Prize for best Oral Presentation
Royal Academy of Medicine in Ireland Registrar's Prize
Irish Society for Cancer Research, Doctor in Training Award
Irish Society of Gastroenterology Prize for best Oral Presentation
'Rising Star' in Gastroenterology for Ireland at the United European Gastroenterology Week
Irish HRB Research Fellowship (2 year)
PPP Healthcare Medical Trust Project grant
Irish HRB Project Grant (On oesophageal cancer)
Irish HRB Project Grant (On Helicobacter pylori)
Trinity College Postgraduate Travelling Scholarship in Medicine
Astra Zeneca Research Grant
Meath Foundation Grant
Best Poster Prize EAGE European Bridging Meeting
IOIBD project grant (International organisation for the study of IBD
Best Poster Prize EAGE Bridging Meeting
ASNEMGE National Scholar Award (Poster Prize UEGW)
British and Irish Gastroenterology (BIG) Meeting Best Oral Presentation
British and Irish Gastroenterology (BIG) Meeting Best Poster Presentation
Irish Society Of Gastroenterology Best Poster Prize
Memberships
The Irish Society of Gastroenterology
The American Gastroenterology Association
The European Society for Gastrointestinal Endoscopy (ESGE)
Uk and Ireland EUS Society (UKIEUS)
Fellow of the Royal College of Physicians in Ireland
ECCO (European Crohn's and Colitis Organisation)