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Latest News

Catriona Gallagher’s video abstract on the ‘’Risk of Skin Cancer and IBD’’ won the 1st Video prize at the ISG Winter Meeting 2017.

The Trinity Academic Gastroenterology Group Tripartite meeting took place in Tallaght Hospital on 17th November 2017. The meeting was chaired by Prof McNamara. Interesting research updates and research proposals were presented along with engaging presentations by external speakers - Dr Otto Mannherz and Dr Jim Coleman.

1.30pm                             Lunch/Arrival
External Speakers
2.00-2.20pm                    Dr Otto Mannherz, R-Biopharm AG
                                          Detection of anti-drug antibodies.
2.25-2.45pm                   Dr Jim Coleman
                                          Reversible Percutaneous Pyloric Narrowing to Treat Obesity and Type 2 DM.
Internal Speakers
2.50-3.00pm                  Introduction to new members
                                         Rita Douglas, Syafiq Ismail.
3.00-3.10pm                  Dr Syafiq Ismail
                                          Study Overview
3.10-3.25pm                 Dr Barry McMahon
                                        Exploring pyloric dynamics in stenting - Using a Distensibility Technique.
                                                              ISG Abstracts Presentation
                                       Tatiana Nuzum
                                       Neil Moran
                                       Jim O'Connell
                                       Ciaran Judge

4.00pm                                                         Updates/Closing Remarks


The 23rd June 2017 was the day of the Trinity Academic Gastroenterology Group Tripartite meeting.
The meeting took place in Naas General Hospital and chaired by Dr Ion Cretu. During the meeting both Research update and Research proposal were presented along with interesting talks given by external speakers.

Welcome
14:00 Dr Ion Cretu

Research update
14:05 Dr Donal Tighe (Immunomonitoring in IBD)
14:20 Dr Catriona Gallagher and Mr Claudio Tersaruolo  (Story board on skin cancer risk)
14:35 Dr Jim O'Connell (Vedolizumab therapeutic drug monitoring)

External 
14:50 Dr Shigeki Nakagome  (Microbiome and IBD)
15:10 Dr Jerome Fennell (Clostridium difficile treatment including F.M.T.)

Research Proposal 15:30 Dr  Anthony O'Connor (F.M.T  for C.R.E  proposal)

Closing
15:50 Dr Ion Cretu


App Screen Shot

The Irish Helicobacter pylori working Group (IHpWG) was established earlier last year to assess, revise and tailor current available recommendations for the treatment of Helicobacter pylori a human pathogen found in up to 25-30% of Irish adults. H. pylori infection can cause stomach ulcers and gastric cancer and when found should be eradicated. The Group developed a consensus clinical guideline to treat and manage H. pylori infection which was published earlier this year. Following this, the IHpWG launched an app called H. pylori Care. The app is designed to enhance access to the clinical guidelines and provide information on the new guidelines released by IHpWG to both clinicians and patients. The launch event took place the 16th of June in the Science Gallery in Trinity College Dublin. The app is now available on Play Store and App Store.

Group Shot






The 7th of April 2017. The TAGG members and other guests  were  joined together in the Trinity Centre in St James’s Hospital to talk about Inflammatory Bowel Disease (IBD) and other related topics.
The agenda was rich and the subject presented were very interesting.
The agenda was as below:
Comparative effectiveness of subcutaneous Anti-TNF therapy in Ulcerative colitis and Crohn’s disease. -
Dr Cathy McShane

Vedolizumab therapeutic drug monitoring in IBD – project overview. - Dr David Kevans

Use of in vitro T cell migration assay to predict IBD patient response to Vedolizumab and serve as model system for drug discovery. - Prof Aideen Long

Novel non-invasive blood pressure monitoring devices – literature review and potential for development within TAGG. - Prof Barry McMahon

Investigating MAIT cell IFNgamma/IL-17 axis in obesity. - Dr Andy Hogan

 


GI Supper Club

The 12th of January 2017 was the date of the first GI Supper Club, an idea of the Trinity Academic Gastroenterology Group (TAGG). The event took place in the beautiful old building of the Royal College of Physicians in Ireland (RCPI) were gastroenterologists and other health care professionals gathered together. The first speaker of the evening was Professor Alex Ford from James’s University Hospital, Leeds, UK discussing GI Symptoms in the Absence of Inflammation in Patients with IBD. The second talk was about the new technologies in genomic: Sean Ennis lecturer in UCD, School of Medicine, Health Sciences Centre was discussing about the project of his company. Between the two lectures dinner was served and the RCPI was the perfect frame for all the event.

GI Supper Club

During the ISG Meeting Event 2016, Dr Mary Hussey won the second prize for her research on the role and feasibility of Colon Capsule Endoscopy (CCE) on patients with incomplete colonoscopies. During the meeting it was highlighted how CCE can reduce diagnostic delays and relieve the burden on other services such as radiology and endoscopy services.

 

 

 

 


Tara Raferty

The UEGW Best Paper Award 2016 was awarded to Dr. Tara Raftery as first author of the winning article "Effects of Vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn's disease: Results from randomised double-blind placebo-controlled study" which was supervised by Associate Professor Maria O'Sullivan. The UEGW Best Paper award recognises the first named author of the best original scientific research published in the UEG Journal in the past year. The article was selected by a panel of experts presided over by Chief Editor Professor Jan Tack and was presented to Dr. Raftery at UEGW, Vienna.

 


meeting

On the 30th September the TAGG members were gathered together in the Robert Grave Postgraduate Centre Trinity Centre/Tallaght Hospital during one of the group’s joint meetings.

In attendance at the meeting there were some guest speakers

The following topics were presented at the meeting

  • Dr. Ion Cretu MRCPI
    A review of the literature exploring the role of Mycobacterium as the potential cause of IBD
  • Prof. James Jones MB,BCh, BAO, BSc, PhD University College of Dublin
    Anorectal sensory dysfunction: translational studies
  • Dr. Sinead Corr Assistant Professor in Microbiology Trinity College Dublin
    Intestinal host-microbe interactions in IBD
  • Dr. Sinead Smith PhD Ussher Assistant Professor Trinity College of Dublin
    Irish Helicobacter pylori Working Group: Guideline update and feedback

pillcam

The TAGG research group successfully held its third Dublin Capsule Endoscopy Course at the Trinity Health Centre at the Adelaide & Meath Hospital on Friday June the 3rd of June 2016. The course enabled participants to gain hands on experience with capsule endoscopy, as well as providing them with an opportunity to attend talks given by experts in the field of capsule endoscopy from Ireland and abroad. We were delighted to welcome Dr. Cristina Carretero from the University of Nevarra Madrid, Spain. Dr. Carretero is considered an international expert in the field of capsule endoscopy with a special interest in Colon Capsule Endoscopy. We received excellent feedback from course participants who were very satisfied with the content and delivery of the course and the TAGG group were delighted to host the course. The course was approved by the RCPI and carried 6 CPD credits.


Shiv-Kirthi

Dr. Shivashini Kirthi has been awarded the National Scholar Award for Ireland at UEG Week 2016 which is given to the highest scoring abstract from each respective country. She will be attending the conference in Vienna in October to receive this award for her abstract “Anti-TNF antibody induced Psoriasis in patients with Inflammatory Bowel Disease ; a prospective Irish cohort study”

 

 

 

 

 


Quality in Endoscopy

 

European Society of Gastrointestinal Endoscopy (ESGE) and European Society for Clinical Nutrition and Metabolism (ESPEN) March 31 - April 1, 2017 Dublin, Ireland Symposium: Quality in Endoscopy

 

 


TAGG is participating in a study with Given Imaging into the use of colon capsules titled 'Pillcam Colonoscopy for incomplete colonoscopy


bmm
Dr. Barry McMahon has just returned from a 3 month visit as an academic professor at the GIOME Research & Innovation Centre in the School of Bioengineering at Chongqing University in China (January to March 2015).

Dr. McMahon was there at the invitation of a collaborator, Prof. Hans Gregersen who set up the GIOME Centre at Chongqing University. He was in China under the Chinese Government Foreign Distinguished Expert Program. Dr. McMahon was working with the research team in GIOME building high performance teams to research and innovate novel medical devices for use in the digestive tract.


The next Joint TAGG meeting will be held in the Robert Smith Lecture Theatre of the Trinity Health Building on the St.James's Hospital site @ 2pm on Friday 8th May.


TAGG co-founder Prof Deirdre McNamara was a speaker at the IMSTA annual conference held at the Crowne Plaza Hotel, Santry on Wednesday 25th March.
The theme of the conference was 'Making It Happen' and Prof McNamara's talk was titled 'Developing Medical Devices in a Healthcare Environment'.


A steering group has been established to form the All Ireland Dysphagia Research Society (AIDRS).  This society aims to:

1.     Promote dissemination and debate of latest research, knowledge on normal feeding, swallowing and dysphagia.

2.     Encourage scientific and clinical investigations in the field of diagnostics, rehabilitation and surgery.

3.     Promote, enhance and encourage interdisciplinary research on normal feeding, swallowing and dysphagia across the island of Ireland.

4.     Attract investigators from a wide range of relevant disciplines to the field.

5.     Attract and encourage new investigators to the field and nurture their development in a practical, supportive environment.

6.     Provide a multidisciplinary forum for presentation of research on normal feeding, swallowing and dysphagia.

You are very welcome to join us for the inaugural meeting on Wednesday January 28th 2015 from 2-5pm in the Anne Young Room, Centre for Learning and Development, St James’s Hospital.

Please email aidrsmeeting@gmail.com to reserve a place at the meeting by 18th December 2014 as places are limited.


The TAGG group will be attending the ISGE Winter meeting 2014 at the Ballsbridge Hotel, Dublin on the 21st and 22nd November where we will have a number of poster and oral presentations at the meeting.

Prof Deirdre McNamara and Dr Sinead Smith were recently awarded a HRB Health Research Award to investigate the prevalence of antibiotic resistant Helicobacter pylori infection and determine whether tailoring treatment based on antibiotic resistance testing improves treatment outcome.

TAGG had their quarterly joint research meeting at St.James's Hospitalon Friday 31st October.Dr. David Kevans was welcomed into the group and gave an interesting talk on his past research areas and potential future research opportunities for the group.Also in attendance was Professor Ross McManus of St. James¹s & TCD who gave an interesting talk on Coeliac Disease Research. Denise Brennan and Aoife Cannon gave brief research updates on their ongoing PhD work in H. pylori and IBDrespectively.


Maria O’Sullivan, Associate Professor in Human Nutrition, in the School of Medicine, Trinity College Dublin, was awarded the Sir David Cuthbertson Medal by the Nutrition Society at the Royal College of Surgeons in London.

Associate Professor O’Sullivan is the first Irish recipient of the Cuthbertson medal in the 23 years since its initiation. Awarded annually since 1990, this honour is awarded to scientists for excellence in nutrition/metabolism research that provides an evidence base for clinical practice.


The TAGG group were well represented at the recent ISGE Summer meeting at Killashee House Hotel in Naas, Co. Kildare on the 12th & 13th June 2014.

The 1st and 2nd Oral Prizes both went to TAGG members.
Dr. Sinead Smith won 1st prize for her presentation, 'Evaluation of a molecular genetics-based approach for the detection of Helicobacter pylori and antibiotic resistance' and Dr. Lina Zgaga claimed the 2nd place for her presentation, 'Plasma Vitamin D Concentration is associated with survival outcome following a diagnosis of colorectal cancer'

Prof. Maria O’Sullivan was the main speaker for the Nutrition session with her talk, titled ‘Vitamin D as an anti-inflammatory therapy in IBD –  new hope or false dawn?’

In total there were 6 posters and 5 oral presentations from the TAGG group as a whole at the ISGE Summer meeting, which shows the quality of research that is being carried out by its members.


DDW ConferenceTAGG will present a poster stand and an exhibit at the Digestive Disease Week Conference 2014 being held in Chicago from the 3rd May - 6th May.DDW is one of the largest and most prominent medical conferences in the world and is a testament to the work being carried out by the group and their research partners.

 

 

We are delighted to announce that Dr Gráinne Holleran has been awarded a prestigious HRB 2014 National SpR/ SR Academic Fellowship Award.
Her achievement is a credit to TAGG, Tallaght Hospital and Trinity College.

TAGG will be holding a joint meeting of the St.James's and Tallaght Hospital members in St.James's Hospital on Friday 14th February at 2pm, the room and agenda will be confirmed shortly.The meeting is also open to anyone that is interested in the groups research themes.Attendance can be confirmed by emailing sbligh@tcd.ie

TAGG had a significant representation at the 2013 ISG Winter meeting in Killarney,Co.Kerry on the 22nd and 23rd November. There were a total of 10 poster presentations and 5 oral presentations from the group.

On the 22nd October at 2.30pm, Tallaght Hospital and Trinity College Dublin Colorectal Cancer Screening Programme launched the results of the second round of the bowel cancer screening programme. With the Minister of Health Dr. James Reilly in attendance together with TAGG co-director Professor Deirdre McNamara, Professor Colm O' Morain, Professor Paul Neary, many of the programme participants and clinical and administrative staff who contributed to the programme's delivery, they presented results that affirmed the success of the programme.

Consistent with the first round screening results, the second round showed that not only is Colorectal Cancer being detected, but dangerous pre-cancerous lesions are being detected and removed before progression. This pilot study was among the first worldwide to assess the relatively new stool based Faecal Immunological Test (FIT) in screening for Colorectal Cancer. The screening programme began in 2008 and since then almost 10,000 men and women, between the ages of 50 and 74, have been offered free bowel screening. This programme has detected
283 precancerous polyps and 49 cancers in the Tallaght population alone. The bowel screening programme will move onto a national basis in the near future with the National Cancer Screening Service as providers but it is only through the hard work,dedication and passion of clinicians such as Professors Colm O' Morain and Deirdre McNamara and their colleagues that the need to screen the population for bowel cancer has been identified.

left to right: Professor Paul Neary,Consultant Surgeon at Tallaght Hospital; Eilish Hardiman, CEO of the new Children's Hospital Group & outgoing CEO of Tallaght Hospital; Dr.James Reilly, Minister for Health

from left to right: Eilish Hardiman, CEO of the new Children's Hospital Group & outgoing CEO of Tallaght Hospital; Professor Deirdre McNamara, Consultant Gastroenterologist, Interim Head of Department of Clinical Medicine & Co-Director of TAGG; Dr. James Reilly, Minister for Health; Professor Paul Neary, Consultant Surgeon at Tallaght Hospital; Mr. Brian Hayes, Minister of State for Public Service Reform and the Office of Public Works.

left to right: Professor Deirdre McNamara,Consultant Gastroenterologist, Interim Head of Department of Clinical Medicine & Co-Director of TAGG; Professor Colm O'Morain, Professor Emeritus, Trinity College Dublin & Consultant Gastroenterologist

Irish Lab Awards 2013TAGG has been nominated for  'Medical Laboratory of the Year' at the Irish Laboratory Awards 2013 which will be held at the DoubleTree by Hilton Hotel Dublin on 3rd December.

In mid October Dr. Gráinne Holleran won the National Scholar Award for Ireland at UEG Week 2013 held in Berlin,the award given to the highest scoring abstract from each respective country for her abstract 'Elevated Angiopoietin 2 Levels in Small Bowel Angiodysplasia; Future Biomarker Or Therapeutic Target'

Tara Raftery (Research Dietitianm PhD student) won best poster presentation at the Irish Nutrition and Dietetic Institute AGM Research Symposium which took place on Saturday 12th October  at the Clyde Court Hotel, Ballsbridge.Tara's presentation entitled "Does vitamin D supplementation impact plasma cathelicidin, human beta defensin 2, and intestinal permeability in stable Crohn’s disease?

Potential mechanisms for its use as an adjunctive therapy in Crohn’s disease"   was selected for 1st prize from 15 presentations in her category.  This research forms part of Tara's PhD studies under the supervision of Prof. Maria O'Sullivan.

On Friday the 6th of September the TAGG research group had their final joint meeting of 2013 in the Trinity Centre of Tallaght Hospital.

There was a very special guest in attendance, Professor Edouard Louis, Head of Gastroenterology at the University Hospital, Belgium and a member of the board of the Scientific Committee of the European Crohn's and Colitis Organisation (2010-2013). Professor Louis presented on Ulcerative Colitis, his experience with UC and optimisation of available treatment options. There was a general discussion afterwards among the group which was both informative and helpful.

In attendance were TAGG Co-Directors Professor Nasir Mahmud and Professor Deirdre McNamara, TAGG co-founder Dr. Barry McMahon, Professor Colm O'Moráin, Professor Nap Keeling and the members of TAGG from Tallaght Hospital and St. James's Hospital.

Also in attendance was Dr.Franco Scaldaferri, a visiting gastroenterologist from the Catholic University of the Sacred Heart, Rome. Dr. Scaldaferri spent 2 weeks with the TAGG group and participated in the weekly group meetings as well as observing the day-to-day work of the group, adding his considerable experience and expertise as a distinguished researcher and publisher. The TAGG group are now planning to develop postgraduate and research links with Dr. Scaldaferri and Professor Gasbarrini's research group in Rome.

After Prof. Louis' presentation, there were research updates from Dr. Barry Hall, Dr. Sinéad Smyth,Tara Raftery and Aoife Cannon. Finally there was a presentation by Dr. Mark Bruzzi of the BioInnovate Ireland Group, a leading forum in medical device innovation in Ireland, which will lead to a collaboration between BioInnovate and TAGG in the near future.

Professor Deirdre McNamara,TAGG Co-Director & Consultant Gastroenterologist with Dr. Franco Scaldaferri,Gastroenterologist & Endoscopist at the Catholic University of the Sacred Heart,Rome Professor Colm O'Moráin,Emeritus Professor of Medicine & Consultant Gastroenterologist Professor Nasir Mahmud, Associate Professor & Consultant Gastroenterologist at St James's Hospital & Co-Director of TAGG
Professor Deirdre McNamara,TAGG Co-Director & Consultant Gastroenterologist with Dr. Franco Scaldaferri,Gastroenterologist & Endoscopist at the Catholic University of the Sacred Heart, Rome

Professor Colm O'Moráin,Emeritus Professor of Medicine & Consultant Gastroenterologist

Professor Nasir Mahmud, Associate Professor & Consultant Gastroenterologist at St James's Hospital & Co-Director of TAGG

 


In mid August the TAGG research group and colleagues participated in the 'Endodex' multi-centre research project at the Adelaide & Meath Hospital involving the use of an colonoscopy simulator in conjunction with the GV2 research group from the School of Computer Sciences & Statistics of Trinity College Dublin.

The study involved video recording and motion sensor measurement of diagnostic
colonoscopy procedures on a colonoscopy training model.No patients were involved.The task for the endoscopists was to find markers in the colon model.

The recorded procedures will be assessed both by the automated system and experts, and association with the endoscopists’ experience and performance indicator data will be analysed. A real-time analysis and feedback system warned the endoscopists if the quality of the procedure was compromised through on-screen feedback and alarms. Therefore, an additional question being addressed by the study is whether the use of the real time feedback system improves screening performance.The recorded procedures will be assessed by a panel of experts and it is hoped the automated system can be improved upon.

'Professor Colm O'Moráin,Emeritus Professor of Medicine & Consultant Gastroenterologist pictured with Mirko Arnold,EndoDex project supervisor' 'Professor Deirdre McNamara,Associate Professor in Gastroenterology, Consultant Gastroenterologist & Co-Director of the TAGG research group'

Professor Colm O'Moráin,Emeritus Professor of Medicine & Consultant Gastroenterologist pictured with Mirko Arnold,EndoDex project supervisor

Professor Deirdre McNamara,Associate Professor in Gastroenterology, Consultant Gastroenterologist & Co-Director of the TAGG research group

 

'The TAGG research group successfully held the Dublin Capsule Endoscopy Course at the Trinity Health Centre at the Adelaide & Meath Hospital on Friday June 7th.The course was approved by the RCPI and carried 6 CPD credits.

The course gave participants to opportunity to attend talks given by experts in the field of capsule endoscopy from Ireland and abroad and also allowed them to gain hands-on experience in viewing case files.

The course participants were highly satisfied with the content and delivery of the course and the TAGG group were delighted to host the course,the first time that a course of this nature has been given in Ireland.

TAGG Dublin Capsule Endoscopy Course 2013
Professor Nasir Mahmud, Associate Professor & Consultant Gastroenterologist, Trinity College Dublin & St James's Hospital Dublin Professor Deirdre McNamara, Associate Professor & Consultant Gastroenterologist and Interim Head of Department of Clinical Medicine Trinity College Dublin & Tallaght Hospital Dr.Christian Bojarski,Consultant Gastroenterologist at the Charité in Berlin Stephen Bligh,Research Assistant and Course Coordiantor of TAGG,Adelaide & Meath Hospital in Dublin
TAGG Dublin Capsule Endoscopy Course 2013
Dr.Gráinne Holleran providing guidance in the hands-on training section of the course
TAGG Dublin Capsule Endoscopy Course 2013
Professor Nasir Mahmud, Associate Professor & Consultant Gastroenterologist, Trinity College Dublin & St James's Hospital Dublin
TAGG Dublin Capsule Endoscopy Course 2013
Dr.Christian Bojarski,Consultant Gastroenterologist at the Charité in Berlin