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Rustom Manecksha
Clinical Senior Lecturer, Surgery

Biography

A graduate from the School of Medicine, University College Dublin in 2000, I was awarded an M.D. from Trinity College Dublin for work on prostate cancer progression to androgen independence. I completed a 2-year Endourology Fellowship at the Austin Hospital in Melbourne, Australia. I was the recipient of the Anthony Walsh/Ipsen/RCSI Travelling Fellowship, the Ethicon Travelling Fellowship and the RCSI Travelling Fellowship. On completion of my clinical fellowship in 2013, I returned to a locum consultant position in St. James's Hospital running the National Cancer Control Programme's rapid access prostate clinic. I was subsequently appointed Consultant Urological Surgeon in St. James's and Tallaght Hospitals, Dublin in 2014. My special interests are in endourology, kidney stone disease, BPH, minimal access renal surgery and prostate cancer. I have an active clinical research profile, with national and international collaborations as well as links with the Institute of Molecular Medicine, Trinity Centre for Health Sciences.

Publications and Further Research Outputs

Peer-Reviewed Publications

Rosie Colgan, Nikita Rajiv Bhatt, Rajiv Merchant, Niall Davis, Michael Leonard, Brendan O"Daly, Rustom Manecksha, John Quinlan, AB115. 128. A 10-year review of genito-urinary injuries in pelvic and acetabular trauma, Mesentery and Peritoneum, 2, (1), 2018, pAB115--AB115 Journal Article, 2018

D'Arcy F, Yip CL, Manya K, McGivern P, Manecksha RP, Bolton D, Sengupta S, Prospective randomised controlled trial of written supplement to verbal communication of results to patients at the time of flexible cystoscopy., World journal of urology, 2018 Journal Article, 2018

Bhatt NR, Merchant R, Davis NF, Leonard M, O'Daly BJ, Manecksha RP, Quinlan JF, Incidence and immediate management of genitourinary injuries in pelvic and acetabular trauma: a 10-year retrospective study., BJU international, 2018 Journal Article, 2018

Davis NF, Cunnane EM, Mooney RC, Manecksha RP, Thornhill JA, Walsh MT, Quantification of User and Manufacturer Variabilities in Urinary Catheter Anchoring Balloon Inflation and Mitigation of Variability by Flow Resistance., Urology, 2017 Journal Article, 2017

O'Connor EM, Nason GJ, Manecksha RP, An Analysis of Gender Diversity in Urology in the UK and Ireland., Irish medical journal, 2017 Journal Article, 2017

Bhatt NR, Davis NF, Nolan WJ, Flynn RJ, McDermott T, Thomas AZ, Manecksha RP, Incidence of Visible Hematuria Among Antithrombotic Agents: A Systematic Review of Over 175,000 Patients., Urology, 2017 Journal Article, 2017

Hennessey DB, Bolton EM, Thomas AZ, Manecksha RP, Lynch TH, The Effect of Obesity and Increased Waist Circumference on the Outcome of Laparoscopic Nephrectomy., Advances in Urology, 2017 Journal Article, 2017

Davis NF, Quinlan MR, Browne C, Bhatt NR, Manecksha RP, D'Arcy FT, Lawrentschuk N, Bolton DM, Single-use flexible ureteropyeloscopy: a systematic review., World journal of urology, 2017 Journal Article, 2017

N. Bhatt, N. Davis, R. Flynn, T. Mcdermott, A. Thomas, R. Manecksha, Antithrombotic agents and haematuria: A systematic review, European Urology Supplements, 16, (3), 2017, pe1194--e1195 Journal Article, 2017

O'Kelly F, Nason GJ, Manecksha RP, Cascio S, Quinn FJ, Leonard M, Koyle MA, Farhat W, Leveridge MJ, The effect of social media (#SoMe) on journal impact factor and parental awareness in paediatric urology., Journal of pediatric urology, 2017 Journal Article, 2017

Bhatt NR, Davis NF, Dalton DM, McDermott T, Flynn RJ, Thomas AZ, Manecksha RP, Quantitative Analysis of Technological Innovation in Urology., Urology, 2017 Journal Article, 2017

Bolton EM, Hennessy D, Lonergan PE, Darcy FT, Manecksha RP, Lynch TH, Evaluating the perioperative safety of laparoscopic radical nephrectomy for large, non-metastatic renal tumours: a comparative analysis of T1-T2 with T3a tumours., Irish journal of medical science, 2017 Journal Article, 2017

O'Connor EM, Nason GJ, O'Kelly F, Manecksha RP, Loeb S, Newsworthiness vs scientific impact: are the most highly cited urology papers the most widely disseminated in the media?, BJU international, 2017 Journal Article, 2017

McLoughlin LC, Inder S, Moran D, O'Rourke C, Manecksha RP, Lynch TH, The value of multimodality imaging in the investigation of a PSA recurrence after radical prostatectomy in the Irish hospital setting., Irish journal of medical science, 2017 Journal Article, 2017

N.R. Bhatt, D.M. Dalton, N.F. Davis, T. McDermott, R.J. Flynn, A.Z. Thomas, R.P. Manecksha, Quantitative analysis of innovation in urology, European Urology Supplements, 16, (3), 2017, pe1434 Journal Article, 2017

Browne C, Norton S, Nolan JM, Whelan C, Sullivan JF, Quinlan M, Sheikh M, Mc Dermott TED, Lynch TH, Manecksha RP, The impact of a structured clinical training course on interns' self-reported confidence with core clinical urology skills., Irish journal of medical science, 2017 Journal Article, 2017

Niall Davis, Eoghan Cunnane, Mark Quinlan, Rustom Manecksha, John Thornhill, David Mulvin, Michael Walsh, PD60-08 INVESTIGATION OF TRAUMATIC URETHRAL CATHETERIZATION AND EVALUATION OF A NOVEL SAFETY SYRINGE AFTER CORRELATING TRAUMA WITH URETHRAL DISTENSION AND CATHETER BALLOON PRESSURE: A PROSPECTIVE MULTI-INSTITUTIONAL STUDY., The Journal of Urology, 197, (4), 2017, pe1185 Journal Article, 2017

Bhatt NR, Davis NF, Quinlan MR, Flynn RJ, McDermott TED, Manecksha RP, Thornhill JA, A prospective audit on the effect of training and educational workshops on the incidence of urethral catheterization injuries., Canadian Urological Association Journal, 2017 Journal Article, 2017

O'Kelly F, Kavanagh S, Manecksha R, Thornhill J, Fennell JP, Characteristics of gram-negative urinary tract infections caused by extended spectrum beta lactamases: pivmecillinam as a treatment option within South Dublin, Ireland., BMC Infectious Diseases, 16, (1), 2016, p620- Journal Article, 2016

Davis NF, Quinlan MR, Bhatt NR, Browne C, MacCraith E, Manecksha R, Walsh MT, Thornhill JA, Mulvin D, Incidence, Cost, Complications and Clinical Outcomes of Iatrogenic Urethral Catheterization Injuries: A Prospective Multi-Institutional Study., The Journal of urology, 2016 Journal Article, 2016

Bhatt NR, Davis NF, Addie D, Flynn R, McDermott TED, Manecksha RP, Thornhill JA, Evaluating the cost of iatrogenic urethral catheterisation injuries., Irish journal of medical science, 2016 Journal Article, 2016

O'Kelly F, Manecksha RP, Quinlan DM, Reid A, Joyce A, O'Flynn K, Speakman M, Thornhill JA, Rates of self-reported 'burnout' and causative factors amongst urologists in Ireland and the UK: a comparative cross-sectional study., BJU international, 2015 Journal Article, 2015

D'Arcy FT, Lawrentschuk N, Manecksha RP, Webb DR, Renal track creation for percutaneous nephrolithotomy: the history and relevance of single stage dilation., The Canadian journal of urology, 2015 Journal Article, 2015

Bhatt NR, Davis NF, Flynn R, McDermott T, Thornhill JA, Manecksha RP, Dilemmas in diagnosis and natural history of renal oncocytoma and implications for management., Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2015 Journal Article, 2015

Davis NF, Burke JP, McDermott T, Flynn R, Manecksha RP, Thornhill JA, Bricker versus Wallace anastomosis: A meta-analysis of ureteroenteric stricture rates after ileal conduit urinary diversion., Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2015 Journal Article, 2015

Nason GJ, O'Kelly F, Bouchier-Hayes D, Quinlan DM, Manecksha RP, Twitter expands the reach and engagement of a national scientific meeting: the Irish Society of Urology., Irish journal of medical science, 2015 Journal Article, 2015

Mertens LS, Mir MC, Scott AM, Lee ST, Fioole-Bruining A, Vegt E, Vogel WV, Manecksha R, Bolton D, Davis ID, Horenblas S, van Rhijn BW, Lawrentschuk N, 18F-fluorodeoxyglucose--positron emission tomography/computed tomography aids staging and predicts mortality in patients with muscle-invasive bladder cancer., Urology, 2014 Journal Article, 2014

Walsh AL, Considine SW, Thomas AZ, Lynch TH, Manecksha RP, Digital rectal examination in primary care is important for early detection of prostate cancer: a retrospective cohort analysis study., The British journal of general practice : the journal of the Royal College of General Practitioners, 2014 Journal Article, 2014

Nason GJ, O'Kelly F, Kelly ME, Phelan N, Manecksha RP, Lawrentschuk N, Murphy DG, The emerging use of Twitter by urological journals., BJU international, 2014 Journal Article, 2014

Chen EC, Manecksha RP, Abouassaly R, Bolton DM, Reich O, Lawrentschuk N, A multilingual evaluation of current health information on the Internet for the treatments of benign prostatic hyperplasia., Prostate international, 2014 Journal Article, 2014

Cullen IM, Manecksha RP, McCullagh E, Ahmad S, O'Kelly F, Flynn R, McDermott TE, Murphy P, Grainger R, Fennell JP, Thornhill JA, An 11-year analysis of the prevalent uropathogens and the changing pattern of Escherichia coli antibiotic resistance in 38,530 community urinary tract infections, Dublin 1999-2009., Irish journal of medical science, 182, (1), 2013, p81-9 Journal Article, 2013

Wetherell DR, Skene A, Manya K, Manecksha RP, Chan Y, Bolton DM, Anastomosing haemangioma of the kidney: a rare morphological variant of haemangioma characteristic of genitourinary tract location., Pathology, 2013 Journal Article, 2013

Rustom Manecksha, Trigonal versus trigone-sparing intradetrusor injection of Botulinum Toxin-A for idiopathic detrusor overactivity, http://isrctn.org/>, 2013 Journal Article, 2013

Chang D, Manecksha RP, Syrrakos K, Lawrentschuk N, An investigation of the basic physics of irrigation in urology and the role of automated pump irrigation in cystoscopy., TheScientificWorldJournal, 2012 Journal Article, 2012

Ahmad S, O'Kelly F, Manecksha RP, Cullen IM, Flynn RJ, McDermott TE, Grainger R, Thornhill JA, Survival after incidental prostate cancer diagnosis at transurethral resection of prostate: 10-year outcomes., Irish journal of medical science, 181, (1), 2012, p27-31 Journal Article, 2012

Maria Carmen Mir, Nathan Papa, Andrew Scott, Rustom Manecksha, Damien Bolton, Ian Davis, Nathan Lawrentschuk, 1894 POSITRON EMISSION TOMOGRAPHY-COMPUTED TOMOGRAPHY (PET-CT) ROLE IN PREDICTING MORTALITY IN PATIENTS WITH METASTATIC BLADDER CANCER, The Journal of Urology, 187, (4), 2012, pe764 Journal Article, 2012

Rustom P. Manecksha, Ivor M. Cullen, Sarfraz Ahmad, Graeme McNeill, Robert Flynn, Thomas E.D. McDermott, Ronald Grainger, John A. Thornhill, Reply from Authors re: Christopher R. Chapple. Which Preparation of Botulinum Toxin A Should Be Used, Where Should It Be Injected, and How Should Its Efficacy Be Assessed? Eur Urol 2012;61:936"37, European Urology, 61, (5), 2012, p938 Journal Article, 2012

Raheem OA, Casey RG, Galvin DJ, Manecksha RP, Varadaraj H, McDermott T, Grainger R, Lynch TH, Discontinuation of anticoagulant or antiplatelet therapy for transrectal ultrasound-guided prostate biopsies: a single-center experience., Korean journal of urology, 2012 Journal Article, 2012

Manecksha RP, Cullen IM, Ahmad S, McNeill G, Flynn R, McDermott TE, Grainger R, Thornhill JA, Prospective Randomised Controlled Trial Comparing Trigone-Sparing versus Trigone-Including Intradetrusor Injection of AbobotulinumtoxinA for Refractory Idiopathic Detrusor Overactivity., European urology, 61, (5), 2012, p928-35 Journal Article, 2012

Dowling CM, Manecksha RP, McGuire C, Swan N, Thornhill JA, Primary paratesticular seminoma - A case report., International journal of surgery case reports, 2012 Journal Article, 2012

Manecksha RP, Nason GJ, Cullen IM, Fennell JP, McEvoy E, McDermott T, Flynn RJ, Grainger R, Thornhill JA, Prospective study of antibiotic prophylaxis for prostate biopsy involving >1100 men., TheScientificWorldJournal, 2012, 2012, p650858 Journal Article, 2012

Cullen IM, Manecksha RP, McCullagh E, Ahmad S, O'Kelly F, Flynn RJ, McDermott T, Murphy P, Grainger R, Fennell JP, Thornhill JA, The changing pattern of antimicrobial resistance within 42 033 Escherichia coli isolates from nosocomial, community and urology patient-specific urinary tract infections, Dublin, 1999-2009., BJU international, 109, (8), 2012, p1198-206 Journal Article, 2012

Rustom P. Manecksha, Ivor M. Cullen, Sarfraz Ahmad, Graeme McNeill, Robert Flynn, Thomas E.D. McDermott, Ronald Grainger, John A. Thornhill, Reply to Pascal Mouracade"s Letter to the Editor re: Rustom P. Manecksha, Ivor M. Cullen, Sarfraz Ahmad, et al. Prospective Randomised Controlled Trial Comparing Trigone-Sparing versus Trigone-Including Intradetrusor Injection of AbobotulinumtoxinA for Refractory Idiopathic Detrusor Overactivity. Eur Urol 2012;61:928"35, European Urology, 61, (5), 2012, pe42 Journal Article, 2012

Campbell N, Barrett S, Halpenny D, Tahir F, Manecksha RP, Feeney J, Hamilton S, Torreggiani WC, Imaging Patterns of Atypical Renal Cell Carcinoma Recurrence: A Pictorial Review., Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 63, (1), 2012, p30-38 Journal Article, 2012 DOI

Ellanti P, Manecksha RP, Flynn R, The use of text messaging to reduce non-attendance at outpatients clinic--a departmental experience., Irish medical journal, 2011 Journal Article, 2011

Thomas AZ, Carrol R, Manecksha RP, Thornhill JA, Grainger R, McDermott TE, Extended long term functional outcome of inflatable penile prosthesis in a single institution., Irish medical journal, 104, (2), 2011, p53-5 Journal Article, 2011

Rustom Manecksha, Ivor Cullen, Sarfraz Ahmad, Graeme McNeill, Ted McDermott, Robert Flynn, Ronald Grainger, John Thornhill, 1962 PROSPECTIVE RANDOMIZED CONTROLLED TRIAL COMPARING TRIGONAL VERSUS TRIGONE-SPARING INTRADETRUSOR INJECTION OF BOTULINUM TOXIN-A FOR REFRACTORY IDIOPATHIC DETRUSOR OVERACTIVITY, The Journal of Urology, 185, (4), 2011, pe785 Journal Article, 2011

O'Kelly F, Manecksha RP, Cullen IM, McDermott TE, Flynn R, Grainger R, Electroejaculatory stimulation and its implications for male infertility in spinal cord injury: a short history through four decades of sperm retrieval (1975-2010)., Urology, 77, (6), 2011, p1349-52 Journal Article, 2011

McNeill GJ, Halpenny D, Campbell N, Manecksha R, Torregianni WC, Re: Reduced radiation exposure with the use of an air retrograde pyelogram during fluoroscopic access for percutaneous nephrolithotomy (from: Lipkin ME, Mancini JG, Zilberman DE, et al. J Endourol 2011;25:563-567)., Journal of endourology, 2011 Journal Article, 2011

Ivor Cullen, Rustom Manecksha, McCullagh Eddie, Ted McDermott, Robert Flynn, Philip Murphy, Ron Grainger, John Thornhill, Jerome Fennell, 1365 THE CHANGING PATTERN OF ANTIMICROBIAL RESISTANCE WITHIN 42033 ESCHERICHIA COLI ISOLATES FROM NOSOCOMIAL, COMMUNITY, AND UROLOGY PATIENT SPECIFIC URINARY TRACT INFECTIONS, DUBLIN 1999"2009, The Journal of Urology, 185, (4), 2011, pe545 Journal Article, 2011

McGuire C, Manecksha RP, Sheils P, McDermott TE, Grainger R, Flynn R, Electroejaculatory stimulation for male infertility secondary to spinal cord injury: the Irish experience in National Rehabilitation Hospital., Urology, 77, (1), 2011, p83-7 Journal Article, 2011

Ahmad S, Manecksha R, Hayes BD, Grainger R, Case report of a symptomatic giant renal oncocytoma., International journal of surgery case reports, 2, (6), 2011, p83-5 Journal Article, 2011

Ahmad S, Manecksha RP, Cullen IM, Flynn RJ, McDermott TE, Grainger R, Thornhill JA, Estimation of clinically significant prostate volumes by digital rectal examination: a comparative prospective study., The Canadian journal of urology, 18, (6), 2011, p6025-30 Journal Article, 2011

Surgical Management of BPH in, editor(s)Roger Dmochowski and Philipp Dahm , Evidence-Based Urology, John Wiley & Sons, 2010, pp103 - 110, [Rustom P. Manecksha and John M. Fitzpatrick] Book Chapter, 2010

Rustom P. Manecksha, Fast Facts: Benign Prostatic Hyperplasia (sixth edition), BJU International, 106, (8), 2010, p1238--1238 Journal Article, 2010

Cheema IA, Manecksha RP, Flynn R, Laparoscopic pyeloplasty., Irish medical journal, 2010 Journal Article, 2010

Rustom P. Manecksha, Succeeding as a Hospital Doctor (third edition), BJU International, 106, (7), 2010, p1088--1088 Journal Article, 2010

Cheema IA, Manecksha RP, Murphy M, Flynn R, Laparoscopic nephrectomy: initial experience with 120 cases., Irish medical journal, 2010 Journal Article, 2010

Rustom P. Manecksha, John M. Fitzpatrick, Surgical Management of Benign Prostatic Hyperplasia, Evidence-Based Urology, 2010, p103--110 Journal Article, 2010

Cullen IM, Cafferty F, Oon SF, Manecksha R, Shields D, Grainger R, McDermott TE, Plunkett P, Meaney J, Lynch TH, Evaluation of suspected renal colic with noncontrast CT in the emergency department: a single institution study., Journal of endourology, 2008 Journal Article, 2008

Rustom P. Manecksha, Succeeding as a hospital doctor (Third edition), BJU International, 100, (4), 2007, p948--948 Journal Article, 2007

R.P. Manecksha, A. Perry, H. Varadaraj, B. Loftus, M.P. Lawler, T.H. Lynch, CAG REPEAT SHORTENING " AN EXPLANATION FOR THE DEVELOPMENT OF ANDROGEN-INDEPENDENT PROSTATE CANCER, European Urology Supplements, 5, (2), 2006, p166 Journal Article, 2006

Sultan S, Manecksha R, O'Sullivan J, Hynes N, Quill D, Courtney D, Survival of ruptured abdominal aortic aneurysms in the west of Ireland: do prognostic indicators of outcome exist?, Vascular and endovascular surgery, 2004 Journal Article, 2004

Connolly SS, O'Toole GC, O'Malley KJ, Manecksha R, O'Brien A, Mulvin DW, Quinlan DM, Positive apical surgical margins after radical retropubic prostatectomy, truth or artefact?, Scandinavian journal of urology and nephrology, 2004 Journal Article, 2004

Manecksha R, Hill AD, Dijkstra B, Kelly L, Collins CD, McDermott E, O'Higgins NJ, Value of sentinel node biopsy in the management of breast cancer., Irish journal of medical science, 2001 Journal Article, 2001

Research Expertise

Description

I have an interest in technology and endourology, in particular, renal stone disease and benign prostate hyperplasia. My other research interests are in prostate cancer, both at molecular and clinical level with involvement in laboratory and clinical research in the area.

Projects

  • Title
    • PERSIST Study
  • Summary
    • Randomized control trial to compare the efficacy and safety of percutaneous nephrostomy with retrograde ureteric stenting for emergency renal decompression in cases of obstruction and sepsis associated with ureteric calculi. The obstructed kidney in the setting of urosepsis is a urological emergency. Stone manipulation in the setting of active, untreated infection with concomitant urinary tract obstruction can lead to life-threatening sepsis. Therefore, urgent decompression of the collecting system is warranted. There are two options for urgent decompression of an obstructed collecting system: Image-guided percutaneous nephrostomy tube placement Cystoscopic retrograde placement of a ureteric stent This strategy allows drainage of infected urine and penetration of antibiotics to the affected renal unit. Definitive stone manipulation should be delayed until the infection is cleared following an appropriate course of antimicrobial therapy. Both the European Association of Urology (EAU) and the American Urological Association (AUA) provide guidelines for management of an obstructed kidney. Both organisations provide evidence-based statements of the highest recommendation that urgent decompression of the kidney is mandated in the setting of sepsis. However, neither organisation recommend one decompression modality over the other. There is a lack of high quality up-to-date evidence to support a consensus view that one method of decompression is superior to the other. This study aims to determine the most effective method of renal decompression in cases of obstruction and sepsis associated with ureteric calculi.
  • Funding Agency
    • Self funded
  • Date From
    • 01/01/2017
  • Title
    • MaSH Study
  • Summary
    • The Men and Sexual Health Prostate Cancer Study is a joint Cancer Council Queensland and Griffith University Queensland project, led by Professor Suzanne Chambers of Griffith University, and coordinated in Ireland by Mr Rustom Manecksha, Consultant Urological Surgeon at St James's and Tallaght Hospitals. This online study will assess concerns about sexual health and what contributes to a man's decision to seek support for their sexual concerns. Part of the purpose of this study is to allow researchers/clinicians to better understand the needs of men so that they can then devise various programmes and resource their rehabilitation accordingly.
  • Funding Agency
    • Cancer Council Queensland
  • Date From
    • 2015
  • Date To
    • 2017
  • Title
    • Risks factors for Flexible Ureteroscope Damage
  • Summary
    • Prospective study of risk factors that increase the likelihood of damage to reusable flexible ureteroscopes. A collaborative study with The Austin Hospital, Melbourne
  • Funding Agency
    • no funding
  • Date From
    • July 2017
  • Date To
    • July 2019

Keywords

Benign prostate surgery; CALCULI; Endoluminal endourology; Endourology; KIDNEY CALCULI; LARGE RENAL CALCULI; PROSTATE; PROSTATE CANCER; RENAL CALCULI; STAGHORN CALCULI; TRANS-URETHRAL PROSTATECTOMY; URETERAL CALCULI

Recognition

Awards and Honours

RCSI Travelling Fellowship 2011

Ethicon Travelling Fellowship 2011

Irish Society of Urology Medal 2010

RCSI-Ipsen-Anthony Walsh Travelling Fellowship 2008

Memberships

Endourological Society 2013 – present

British Association of Urology 2003 – present

British Association of Urology (Subsection of Endourology) 2013 – present

European Association of Urology 2003 – present

Irish Society of Urology 2003 – present

Americal Urological Association 2005 – present