The Neuropharmacology group uses mainly in vivo electrophysiological techniques to address research questions like: What mechanisms underlie the different forms of synaptic plasticity in the hippocampus, in particular long-term potentiation (LTP), long-term depression (LTD) and their reversal? Which forms of synaptic plasticity are behaviourally relevant and how are they regulated by extrahippocampal inputs? How does sleep-wake cycle affect synaptic plasticity? A major focus of our research is how misfolded proteins affect synaptic plasticity, in particular the Alzheimer's disease-related amyloid ß protein (Aß).
For further information about Professor Michael Rowan please view his CV Profile.
For further references please visit the Institute of Neuroscience website