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Arun Bokde
Assistant Professor, School Office - Medicine
Assistant Professor, Psychiatry
Assistant Professor, Trinity Inst. of Neurosciences (TCIN)

Biography

Arun Bokde is Assistant Professor in Neuroimaging in the Discipline of Psychiatry, School of Medicine, at Trinity College Dublin. He leads the Cognitive Systems Group, is a principal investigator in the Trinity College Institute of Neuroscience (TCIN), and a member of the Global Brain Health Institute (GBHI). His initial appointment at Trinity College Dubiln was as SFI Stokes Lecturer in Biostatistical Imaging. Arun Bokde is member of two large European neuroimaging: the European DTI Study on Dementia (EDSD) and IMAGEN, a study of high-risk behaviors and mental disorders in adolescence. Before coming to Trinity College Dublin he was a Research Scientist at Ludwig Maximilian University in Munich, Germany; and previously he was a Postdoctoral Research Fellow at the National Institute on Aging and at the National Institute of Mental Health, both at the National Institutes of Health (USA). His first post-doctoral position was at Nothwestern University (USA). He obtained his PhD degree at the University of Texas at Austin. He has published widely on the risk factors that lead to the development of mental health disorders in young and older populations.

Publications and Further Research Outputs

Peer-Reviewed Publications

Xu B, Jia T, Macare C, Banaschewski T, Bokde A.L.W, Bromberg U, BÌchel C, Cattrell A, Conrod P.J, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot J.-L, PaillÚre Martinot M.-L, Nees F, Orfanos D.P, Paus T, Poustka L, Smolka M.N, Walter H, Whelan R, Schumann G, DesriviÚres S, Banaschewski T, Barker G, Bokde A.L.W, Bromberg U, BÌchel C, Quinlan E.B, DesriviÚres S, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot J.-L, PaillÚre Martinot M.-L, Artiges E, Lemaitre H, Nees F, Orfanos D.P, Paus T, Poustka L, Smolka M.N, Vetter N.C, Jurk S, Mennigen E, Walter H, Whelan R, Schumann G, Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder, Journal of the American Academy of Child and Adolescent Psychiatry, 56, (5), 2017, p436 - 444.e4 Journal Article, 2017 URL DOI

Deng W, Rolls ET, Ji X, Robbins TW, Banaschewski T, Bokde ALW, Bromberg U, Buechel C, Desrivières S, Conrod P, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Lemaitre H, Nees F, Papadopoulos Orfanos D, Poustka L, Smolka MN, Walter H, Whelan R, Schumann G, Feng J, Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition., Human Brain Mapping, 38, (7), 2017, p3527-3537 Journal Article, 2017 DOI

Quinlan E.B, Cattrell A, Jia T, Artiges E, Banaschewski T, Barker G, Bokde A.L.W, Bromberg U, BÌchel C, BrÌhl R, Conrod P.J, Desrivieres S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot J.-L, Martinot M.-L.P, Nees F, Papadopoulos-Orfanos D, Paus T, Poustka L, Smolka M.N, Vetter N.C, Walter H, Whelan R, Glennon J.C, Buitelaar J.K, Happé F, Loth E, Barker E.D, Schumann G, Psychosocial stress and brain function in adolescent psychopathology, American Journal of Psychiatry, 174, (8), 2017, p785 - 794 Journal Article, 2017 URL DOI

Khan W, Giampietro V, Banaschewski T, Barker G.J, Bokde A.L.W, BÌchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaître H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka M.N, Ströhle A, Gallinat J, Vellas B, Soininen H, Kloszewska I, Tsolaki M, Mecocci P, Spenger C, Villemagne V.L, Masters C.L, Muehlboeck J.-S, BÀckman L, Fratiglioni L, Kalpouzos G, Wahlund L.-O, Schumann G, Lovestone S, Williams S.C.R, Westman E, Simmons A, A Multi-Cohort Study of ApoE ϵ 4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease, Journal of Alzheimer's Disease, 56, (3), 2017, p1159 - 1174 Journal Article, 2017 DOI URL

Mielenz D, Reichel M, Jia T, Quinlan EB, Stöckl T, Mettang M, Zilske D, Kirmizi-Alsan E, Schönberger P, Praetner M, Huber SE, Amato D, Schwarz M, Purohit P, Brachs S, Spranger J, Hess A, Büttner C, Ekici AB, Perez-Branguli F, Winner B, Rauschenberger V, Banaschewski T, Bokde AL, Büchel C, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot JL, Lemaitre H, Nees F, Paus T, Smolka MN; IMAGEN Consortium., Schambony A, Bäuerle T, Eulenburg V, Alzheimer C, Lourdusamy A, Schumann G, Müller CP., EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction., Molecular Psychiatry, 2017, p1 - 7 Journal Article, 2017 DOI TARA - Full Text

BÃ"chel C, Peters J, Banaschewski T, Bokde A.L.W, Bromberg U, Conrod P.J, Flor H, Papadopoulos D, Garavan H, Gowland P, Heinz A, Walter H, Ittermann B, Mann K, Martinot J.-L, PaillÃ"re-Martinot M.-L, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Robbins T.W, Smolka M.N, Gallinat J, Schumann G, Knutson B, Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents, Nature Communications, 8, 2017, p14140- Journal Article, 2017 DOI TARA - Full Text URL

Cavedo E, Lista S, Rojkova K, Chiesa P.A, Houot M, Brueggen K, Blautzik J, Bokde A.L.W, Dubois B, Barkhof F, Pouwels P.J.W, Teipel S, Hampel H, Disrupted white matter structural networks in healthy older adult APOE ε4 carriers â€" An international multicenter DTI study, Neuroscience, 357, 2017, p119 - 133 Journal Article, 2017 URL DOI

Frauke Nees, Susanne Becker, Sabina Millenet, Tobias Banaschewski, Luise Poustka, Arun Bokde, Uli Bromberg, Christian Büchel, Patricia J Conrod, Sylvane Desrivières, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Dimitri Papadopoulos Orfanos, Tomá Paus, Michael N Smolka, Henrik Walter, Rob Whelan, Gunter Schumann, Herta Flor, IMAGEN consortium, Brain substrates of reward processing and the μ-opioid receptor: a pathway into pain?, Pain, 158, (2), 2017, p212 - 219 Journal Article, 2017 DOI

Bourque J, Spechler PA, Potvin S, Whelan R, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Quinlan EB, Desrivières S, Flor H, Frouin V, Gowland P, Heinz A, Ittermann B, Martinot JL, Paillère-Martinot ML, McEwen SC, Nees F, Orfanos DP, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Schumann G, Garavan H, Conrod PJ; IMAGEN Consortium, Functional Neuroimaging Predictors of Self-Reported Psychotic Symptoms in Adolescents., American Journal of Psychiatry, 174, (6), 2017, p566-575 Journal Article, 2017 DOI

Duka T, Nikolaou K, King SL, Banaschewski T, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Flor H, Gallinat J, Garavan H, Heinz A, Jia T, Gowland P, Martinot JL, Paus T, Rietschel M, Robbins TW, Smolka M, Schumann G, Stephens DN., GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents., Frontiers in Behavioral Neuroscience, 2017, p1-- Journal Article, 2017 DOI TARA - Full Text

Sibilia F, Kehoe EG, Farrell D, Kerskens C, O'Neill D, McNulty JP, MullinsP, Bokde ALW., Aging-related microstructural alterations along the length of the cingulum bundle, Brain Connectivity, 2017 Journal Article, 2017 DOI URL

Savani Bartholdy, Karina Allen, John Hodsoll, Owen G O'Daly, Iain C Campbell, Tobias Banaschewski, Arun LW Bokde, Uli Bromberg, Christian Büchel, Erin Burke Quinlan, Patricia J Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomá Paus, Luise Poustka, Michael N Smolka, Eva Mennigen, Henrik Walter, Robert Whelan, Gunter Schumann, Ulrike Schmidt, Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age?, European Child & Adolescent Psychiatry, 2017, p1 - 11 Journal Article, 2017 URL

Brueggen K, Grothe MJ, Dyrba M, Fellgiebel A, Fischer F, Filippi M, Agosta F, Nestor P, Meisenzahl E, Blautzik J, Frölich L, Hausner L, Bokde AL, Frisoni G, Pievani M, Klöppel S, Prvulovic D, Barkhof F, Pouwels PJ, Schröder J, Hampel H, Hauenstein K, Teipel S., The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment., Neuroimage, 144, 2017, p305 - 308 Journal Article, 2017 DOI

Gollier-Briant F, Paillère-Martinot ML, Lemaitre H, Miranda R, Vulser H, Goodman R, Penttilä J, Struve M, Fadai T, Kappel V, Poustka L, Grimmer Y, Bromberg U, Conrod P, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Flor H, Gallinat J, Garavan H, Heinz A, Lawrence C, Mann K, Nees F, Paus T, Pausova Z, Frouin V, Rietschel M, Robbins TW, Smolka MN, Schumann G; IMAGEN Consortium+., Martinot JL, Artiges E, Neural correlates of three types of negative life events during angry face processing in adolescents., Social cognitive and affective neuroscience, 11, (12), 2016, p1961 - 1969 Journal Article, 2016 DOI

Keith B Burt, Robert Whelan, Patricia J Conrod, Tobias Banaschewski, Gareth J Barker, Arun LW Bokde, Uli Bromberg, Christian Büchel, Mira Fauth‐Bühler, Herta Flor, André Galinowski, Juergen Gallinat, Penny Gowland, Andreas Heinz, Bernd Ittermann, Karl Mann, Frauke Nees, Dimitri Papadopoulos‐Orfanos, Tomas Paus, Zdenka Pausova, Luise Poustka, Marcella Rietschel, Trevor W Robbins, Michael N Smolka, Andreas Ströhle, Gunter Schumann, Hugh Garavan, Structural brain correlates of adolescent resilience, Journal of Child Psychology and Psychiatry, 57, (11), 2016, p1287 - 1296 Journal Article, 2016 URL

Jia T, Macare C, DesriviÚres S, Gonzalez D.A, Tao C, Ji X, Ruggeri B, Nees F, Banaschewski T, Barker G.J, Bokde A.L.W, Bromberg U, BÌchel C, Conrod P.J, Dove R, Frouin V, Gallinat J, Garavan H, Gowland P.A, Heinz A, Ittermann B, Lathrop M, Lemaitre H, Martinot J.-L, Paus T, Pausova Z, Poline J.-B, Rietschel M, Robbins T, Smolka M.N, MÌller C.P, Feng J, Rothenfluh A, Flor H, Schumann G, Neural basis of reward anticipation and its genetic determinants, Proceedings of the National Academy of Sciences of the United States of America, 113, (14), 2016, p3879 - 3884 Journal Article, 2016 DOI URL

Heinrich A, MÌller K.U, Banaschewski T, Barker G.J, Bokde A.L.W, Bromberg U, BÌchel C, Conrod P, Fauth-BÌhler M, Papadopoulos D, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Mann K, Martinot J.-L, Paus T, Pausova Z, Smolka M, Ströhle A, Rietschel M, Flor H, Schumann G, Nees F, Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity, Biological Psychology, 118, 2016, p79 - 87 Journal Article, 2016 URL DOI

Peña-Oliver Y, Carvalho FM, Sanchez-Roige S, Quinlan EB, Jia T, Walker-Tilley T, Rulten SL, Pearl FM, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod PJ, Flor H, Gallinat J, Garavan H, Heinz A, Gowland P, Paillere Martinot ML, Paus T, Rietschel M, Robbins TW, Smolka MN, Schumann G, Stephens DN, Mouse and Human Genetic Analyses Associate Kalirin with Ventral Striatal Activation during Impulsivity and with Alcohol Misuse., Frontiers in genetics, 7, 2016, p52 Journal Article, 2016 DOI

Castellanos-Ryan N, Brière FN, O'Leary-Barrett M, Banaschewski T, Bokde A, Bromberg U, Büchel C, Flor H, Frouin V, Gallinat J, Garavan H, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Robbins TW, Whelan R, Schumann G, Conrod P; IMAGEN Consortium, The structure of psychopathology in adolescence and its common personality and cognitive correlates, Journal of Abnormal Psychology, 125, (8), 2016, p1039 - 1052 Journal Article, 2016 DOI

Ewald A, Becker S, Heinrich A, Banaschewski T, Poustka L, Bokde A, BÃ"chel C, Bromberg U, Cattrell A, Conrod P, DesriviÃ"res S, Frouin V, Papadopoulos-Orfanos D, Gallinat J, Garavan H, Heinz A, Walter H, Ittermann B, Gowland P, Paus T, Martinot J.-L, PaillÃ"re Martinot M.-L, Smolka M.N, Vetter N, Whelan R, Schumann G, Flor H, Nees F, The role of the cannabinoid receptor in adolescents' processing of facial expressions, European Journal of Neuroscience, 43, (1), 2016, p98 - 105 Journal Article, 2016 URL

Jollans L, Zhipeng C, Icke I, Greene C, Kelly C, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Artiges E, Nees F, Papadopoulos Orfanos D, Paus T, Smolka MN, Walter H, Schumann G, Whelan R, Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers., Developmental neuropsychology, 41, (1-2), 2016, p6-21 Journal Article, 2016 DOI

Raffaelli B, Strache N, Parchetka C, Artiges E, Banaschewski T, Bokde A, Bromberg U, Buechel C, Cattrell A, Conrod P, Flor H, Frouin V, Garavan H, Heinrich A, Heinz A, Ittermann B, Jurk S, Lemaitre H, Martinot J.-L, Mennigen E, Martinot M.-L.P, Papadopoulos D, Paus T, Poustka L, Smolka M.N, Vetter N.C, Walter H, Whelan R, Schumann G, Gallinat J, Sex-related differences in frequency and perception of stressful life events during adolescence, Journal of Public Health (Germany), 24, (5), 2016, p365 - 374 Journal Article, 2016 URL DOI

Mackey S, Chaarani B, Kan K.-J, Spechler P.A, Orr C, Banaschewski T, Barker G, Bokde A.L.W, Bromberg U, BÃ"chel C, Cattrell A, Conrod P.J, DesriviÃ"res S, Flor H, Frouin V, Gallinat J, Gowland P, Heinz A, Ittermann B, PaillÃ"re Martinot M.-L, Artiges E, Nees F, Papadopoulos-Orfanos D, Poustka L, Smolka M.N, Jurk S, Walter H, Whelan R, Schumann G, Althoff R.R, Garavan H, Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior, Biological Psychiatry, 2016 Journal Article, 2016 URL DOI TARA - Full Text

Lancaster, T.M., Linden, D.E., Tansey, K.E., (...), Whelan, R., Schumann, G. , Mouse and human genetic analyses associate kalirin with ventral striatal activation during impulsivity and with alcohol misuse, Frontiers in Genetics, 73, (8), 2016, p852-861 Journal Article, 2016 URL TARA - Full Text DOI

Connolly J, McNulty JP, Boran L, Roche RA, Delany D, Bokde AL, Identification of Resting State Networks Involved in Executive Function., Brain connectivity, 6, (5), 2016, p365 - 374 Journal Article, 2016 DOI

Ciblis, A. S., Butler, M.-L., Quinn, C., Clare, L., Bokde, A. L., Mullins, P. G., McNulty, J. P., Current Practice in the Referral of Individuals with Suspected Dementia for Neuroimaging by General Practitioners in Ireland and Wales, PloS One, 11, (3), 2016, pe0151793 Journal Article, 2016 TARA - Full Text DOI

N Mikita, E Simonoff, DS Pine, R Goodman, E Artiges, T Banaschewski, AL Bokde, U Bromberg, C Büchel, A Cattrell, PJ Conrod, S Desrivières, H Flor, V Frouin, J Gallinat, H Garavan, A Heinz, B Ittermann, S Jurk, JL Martinot, ML Paillère Martinot, F Nees, D Papadopoulos Orfanos, T Paus, L Poustka, MN Smolka, H Walter, R Whelan, G Schumann, A Stringaris, Disentangling the autism- anxiety overlap: fMRI of reward processing in a community-based longitudinal study, Translational psychiatry, 6, 2016, pe845 Journal Article, 2016 DOI URL

Lancaster T.M, Linden D.E, Tansey K.E, Banaschewski T, Bokde A.L.W, Bromberg U, BÃŒchel C, Cattrell A, Conrod P.J, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot J.-L, Martinot M.-L.P, Artiges E, Lemaitre H, Nees F, Orfanos D.P, Paus T, Poustka L, Smolka M.N, Vetter N.C, Jurk S, Mennigen E, Walter H, Whelan R, Schumann G, Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents, JAMA Psychiatry, 73, (8), 2016, p852 - 861 Journal Article, 2016 URL DOI

Ruggeri B, Nymberg C, Vuoksimaa E, Lourdusamy A, Wong CP, Carvalho FM, Jia T, Cattrell A, Macare C, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Nees F, Pausova Z, Paus T, Rietschel M, Robbins T, Smolka MN, Spanagel R, Bakalkin G, Mill J, Sommer WH, Rose RJ, Yan J, Aliev F, Dick D, Kaprio J, Desrivières S, Schumann G, Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis., The American journal of psychiatry, 172, (6), 2015, p543-52 Journal Article, 2015 DOI TARA - Full Text

Ciblis A.S, Butler M.-L, Bokde A.L.W, Mullins P.G, McNulty J.P, The use of neuroimaging in dementia by Irish general practitioners, Irish Journal of Medical Science , 185, (3), 2015, p597-602 Journal Article, 2015 URL DOI

Cury C, Toro R, Cohen F, Fischer C, Mhaya A, Samper-González J, Hasboun D, Mangin JF, Banaschewski T, Bokde AL, Bromberg U, Buechel C, Cattrell A, Conrod P, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaitre H, Martinot JL, Nees F, Paillère Martinot ML, Orfanos DP, Paus T, Poustka L, Smolka MN, Walter H, Whelan R, Frouin V, Schumann G, Glaunès JA, Colliot O, Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects., Frontiers in neuroanatomy, 9, 2015, p160 Journal Article, 2015 DOI TARA - Full Text

O'Leary-Barrett M, Pihl RO, Artiges E, Banaschewski T, Bokde AL, Büchel C, Flor H, Frouin V, Garavan H, Heinz A, Ittermann B, Mann K, Paillère-Martinot ML, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Conrod PJ, Personality, Attentional Biases towards Emotional Faces and Symptoms of Mental Disorders in an Adolescent Sample., PloS one, 10, (6), 2015, pe0128271 Journal Article, 2015 TARA - Full Text DOI

Ojelade SA, Jia T, Rodan AR, Chenyang T, Kadrmas JL, Cattrell A, Ruggeri B, Charoen P, Lemaitre H, Banaschewski T, Büchel C, Bokde AL, Carvalho F, Conrod PJ, Flor H, Frouin V, Gallinat J, Garavan H, Gowland PA, Heinz A, Ittermann B, Lathrop M, Lubbe S, Martinot JL, Paus T, Smolka MN, Spanagel R, O'Reilly PF, Laitinen J, Veijola JM, Feng J, Desrivières S, Jarvelin MR, Schumann G, Rothenfluh A, Rsu1 regulates ethanol consumption in Drosophila and humans., Proceedings of the National Academy of Sciences of the United States of America, 2015, pE4085 - E4093 Journal Article, 2015 URL

Vulser H, Lemaitre H, Artiges E, Miranda R, Penttilä J, Struve M, Fadai T, Kappel V, Grimmer Y, Goodman R, Stringaris A, Poustka L, Conrod P, Frouin V, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Loth E, Mann K, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Schumann G, Martinot JL, Paillère-Martinot ML, Subthreshold Depression and Regional Brain Volumes in Young Community Adolescents., Journal of the American Academy of Child and Adolescent Psychiatry, 54, (10), 2015, p832-40 Journal Article, 2015 DOI

Kehoe EG, Farrell D, Metzler-Baddeley C, Lawlor BA, Kenny RA, Lyons D, McNulty JP, Mullins PG, Coyle D, Bokde AL, Fornix White Matter is Correlated with Resting-State Functional Connectivity of the Thalamus and Hippocampus in Healthy Aging but Not in Mild Cognitive Impairment - A Preliminary Study., Frontiers in aging neuroscience, 7, 2015, p10 Journal Article, 2015 DOI TARA - Full Text

Ciblis AS, Butler ML, Bokde ALW, Mullins PG, O'Neill D, McNulty JP, Neuroimaging referral for dementia diagnosis: The specialist's perspective in Ireland, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 1, (1), 2015, p41 - 47 Journal Article, 2015 TARA - Full Text DOI URL

Stacey D, Lourdusamy A, Ruggeri B, Maroteaux M, Jia T, Cattrell A, Nymberg C, Banaschewski T, Bhattacharyya S, Band H, Barker G, Bokde A, Buchel C, Carvalho F, Conrod P, Desrivieres S, Easton A, Fauth-Buehler M, Fernandez-Medarde A, Flor H, Frouin V, Gallinat J, Garavanh H, Heinz A, Ittermann B, Lathrop M, Lawrence C, Loth E, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Rotter A, Santos E, Smolka M, Sommer W, Mameli M, Spanagel R, Girault JA, Mueller C, Schumann G, A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males., Journal of psychiatry & neuroscience : JPN, 41, (2), 2015, p150138 Journal Article, 2015 TARA - Full Text URL

Featherstone, H., Butler, M. L., Ciblis, A., Bokde, A. L., Mullins, P. G., & McNulty, J. P., What do people with dementia and their carers want to know about neuroimaging for dementia? , Dementia, 2015, pDOI:10.1177/1471301215602576 Journal Article, 2015

Jurk S, Kuitunen-Paul S, Kroemer NB, Artiges E, Banaschewski T, Bokde AL, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Heinz A, Mann KF, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Schumann G, Struve M, Smolka MN, Personality and Substance Use: Psychometric Evaluation and Validation of the Substance Use Risk Profile Scale (SURPS) in English, Irish, French, and German Adolescents., Alcoholism, clinical and experimental research, 39, (11), 2015, p2234-48 Journal Article, 2015 DOI

Fritsch V, Da Mota B, Loth E, Varoquaux G, Banaschewski T, Barker GJ, Bokde AL, Brühl R, Butzek B, Conrod P, Flor H, Garavan H, Lemaitre H, Mann K, Nees F, Paus T, Schad DJ, Schümann G, Frouin V, Poline JB, Thirion B, Robust regression for large-scale neuroimaging studies., NeuroImage, 111, 2015, p431-441 Journal Article, 2015 TARA - Full Text DOI

Fitzgerald J, Johnson K, Kehoe E, Bokde AL, Garavan H, Gallagher L, McGrath J, Disrupted Functional Connectivity in Dorsal and Ventral Attention Networks During Attention Orienting in Autism Spectrum Disorders., Autism research : official journal of the International Society for Autism Research, 8, (2), 2015, p136-152 Journal Article, 2015 DOI

Nees F, Witt SH, Dinu-Biringer R, Lourdusamy A, Tzschoppe J, Vollstädt-Klein S, Millenet S, Bach C, Poustka L, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Frank J, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Mann K, Martinot JL, Paus T, Pausova Z, Robbins TW, Smolka MN, Rietschel M, Schumann G, Flor H, BDNF Val66Met and reward-related brain function in adolescents: Role for early alcohol consumption., Alcohol (Fayetteville, N.Y.), 49, (2), 2015, p103-10 Journal Article, 2015 DOI

Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty MM, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Lemaître H, Mann KF, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Spanagel R, Ströhle A, Schumann G, Hawrylycz M, Poline JB, Greicius MD, BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain networks., Science (New York, N.Y.), 348, (6240), 2015, p1241-4 Journal Article, 2015 DOI

Li X, Kehoe EG, McGinnity TM, Coyle D, Bokde AL, Modulation of Effective Connectivity in the Default Mode Network at Rest and During a Memory Task, Brain Connectivity, 5, (1), 2015, 60-67 Journal Article, 2015 DOI

French L, Gray C, Leonard G, Perron M, Pike G.B, Richer L, Séguin J.R, Veillette S, Evans C.J, Artiges E, Banaschewski T, Bokde A.W.L, Bromberg U, Bruehl R, Buchel C, Cattrell A, Conrod P.J, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Lemaitre H, Martinot J.-L, Nees F, Orfanos D.P, Pangelinan M.M, Poustka L, Rietschel M, Smolka M.N, Walter H, Whelan R, Timpson N.J, Schumann G, Smith G.D, Pausova Z, Paus T, Early cannabis use, polygenic risk score for schizophrenia, and brain maturation in adolescence, JAMA Psychiatry, 72, (10), 2015, p1002 - 1011 Journal Article, 2015 DOI URL

Desrivières S, Lourdusamy A, Tao C, Toro R, Jia T, Loth E, Medina LM, Kepa A, Fernandes A, Ruggeri B, Carvalho FM, Cocks G, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod PJ, Flor H, Heinz A, Gallinat J, Garavan H, Gowland P, Brühl R, Lawrence C, Mann K, Martinot ML, Nees F, Lathrop M, Poline JB, Rietschel M, Thompson P, Fauth-Bühler M, Smolka MN, Pausova Z, Paus T, Feng J, Schumann G, Single nucleotide polymorphism in the neuroplastin locus associates with cortical thickness and intellectual ability in adolescents, Molecular Psychiatry, 2015, p0-0 Journal Article, 2015 TARA - Full Text DOI

Dyrba M, Barkhof F, Fellgiebel A, Filippi M, Hausner L, Hauenstein K, Kirste T, Teipel S.J, Agosta E, Blautzik J, Bokde A.L.W, Ewers M, Fischer F, Frisoni G.B, Frolich L, Hampel H, Hentschel F, HÌll M, Jessen F, Kljajevic V, Klöppel S, Meindl T, O'Dwyer L, Pievani M, Pouwels P.J.W, Predicting Prodromal Alzheimer's Disease in Subjects with Mild Cognitive Impairment Using Machine Learning Classification of Multimodal Multicenter Diffusion-Tensor and Magnetic Resonance Imaging Data, Journal of Neuroimaging, 25, (5), 2015, p738 - 747 Journal Article, 2015 URL DOI

Spechler P.A, Orr C.A, Chaarani B, Kan K.-J, Mackey S, Morton A, Snowe M.P, Hudson K.E, Althoff R.R, Higgins S.T, Cattrell A, Flor H, Nees F, Banaschewski T, Bokde A.L.W, Whelan R, BÃŒchel C, Bromberg U, Conrod P, Frouin V, Papadopoulos D, Gallinat J, Heinz A, Walter H, Ittermann B, Gowland P, Paus T, Poustka L, Martinot J.-L, Artiges E, Smolka M.N, Schumann G, Garavan H, Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat, Developmental Cognitive Neuroscience, 16, 2015, p63 - 70 Journal Article, 2015 URL TARA - Full Text DOI

Müller KU, Gan G, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Loth E, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Ströhle A, Struve M, Schumann G, Smolka MN; IMAGEN Consortium, No differences in ventral striatum responsivity between adolescents with a positive family history of alcoholism and controls, Addiction biology, 20, (3), 2015, p534-545 Journal Article, 2015 DOI

Dell'Acqua F, Khan W, Gottlieb N, Giampietro V, Ginestet C, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Lemaítre H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A, Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE "4 and "2 Alleles in Young Healthy Adolescents., Journal of Alzheimer's disease : JAD, 47, (4), 2015, p977-984 Journal Article, 2015 DOI

Bokde A.L.W, Cavedo E, Lopez-Bayo P, Lista S, Meindl T, Born C, Galluzzi S, Faltraco F, Dubois B, Teipel S.J, Reiser M, Möller H.-J, Hampel H, Effects of rivastigmine on visual attention in subjects with amnestic mild cognitive impairment: A serial functional MRI activation pilot-study, Psychiatry Research: Neuroimaging, 249, 2015, p84-90 Journal Article, 2015 DOI URL

Lista S, Molinuevo JL, Cavedo E, Rami L, Amouyel P, Teipel SJ, Garaci F, Toschi N, Habert MO, Blennow K, Zetterberg H, O'Bryant SE, Johnson L, Galluzzi S, Bokde AL, Broich K, Herholz K, Bakardjian H, Dubois B, Jessen F, Carrillo MC, Aisen PS, Hampel H, Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline., Journal of Alzheimer's disease : JAD, 48, (s1), 2015, pS171-S191 Journal Article, 2015 DOI

Stringaris A, Vidal-Ribas Belil P, Artiges E, Lemaitre H, Gollier-Briant F, Wolke S, Vulser H, Miranda R, Penttilä J, Struve M, Fadai T, Kappel V, Grimmer Y, Goodman R, Poustka L, Conrod P, Cattrell A, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Nees F, Papadopoulos D, Paus T, Smolka MN, Walter H, Whelan R, Martinot JL, Schumann G, Paillère-Martinot ML, The Brain's Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample., The American journal of psychiatry, 172, (12), 2015, p1215-1223 Journal Article, 2015 DOI

Ortuño-Sierra J, Fonseca-Pedrero E, Aritio-Solana R, Velasco AM, de Luis EC, Schumann G, Cattrell A, Flor H, Nees F, Banaschewski T, Bokde A, Whelan R, Buechel C, Bromberg U, Conrod P, Frouin V, Papadopoulos D, Gallinat J, Garavan H, Heinz A, Walter H, Struve M, Gowland P, Paus T, Poustka L, Martinot JL, Paillère-Martinot ML, Vetter NC, Smolka MN, Lawrence C, New evidence of factor structure and measurement invariance of the SDQ across five European nations., European child & adolescent psychiatry, 24, (12), 2015, p1523-1534 Journal Article, 2015 DOI

Richiardi J, Altmann A, Milazzo A.-C, Chang C, Chakravarty M.M, Banaschewski T, Barker G.J, Bokde A.L.W, Bromberg U, BÌchel C, Conrod P, Fauth-BÌhler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Lemaître H, Mann K.F, Martinot J.-L, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T.W, Smolka M.N, Spanagel R, Ströhle A, Schumann G, Hawrylycz M, Poline J.-B, Greicius M.D, Correlated gene expression supports synchronous activity in brain networks, Science, 348, (6240), 2015, p1241 - 1244 Journal Article, 2015 URL DOI

Da Mota, B., Fritsch, V., Varoquaux, G., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Conrod, P., Gallinat, J., Garavan, H., Martinot, J.-L., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Smolka, M.N., Ströhle, A., Frouin, V., Poline, J.-B., Thirion, B., Randomized parcellation based inference, NeuroImage, 89, 2014, p203-215 Journal Article, 2014 TARA - Full Text DOI

Kehoe EG, McNulty JP, Mullins PG, Bokde AL, Advances in MRI biomarkers for the diagnosis of Alzheimer's disease, Biomarkers in Medicine, 8, (9), 2014, p1151 - 1169 Journal Article, 2014 DOI

Toro R, Poline JB, Huguet G, Loth E, Frouin V, Banaschewski T, Barker GJ, Bokde A, Büchel C, Carvalho FM, Conrod P, Fauth-Bühler M, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Lemaître H, Mann K, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T, Smolka MN, Ströhle A, Schumann G, Bourgeron T, Genomic architecture of human neuroanatomical diversity, Molecular psychiatry, 2014, p1-6 Journal Article, 2014 DOI TARA - Full Text

Dickie EW, Tahmasebi A, French L, Kovacevic N, Banaschewski T, Barker GJ, Bokde A, Büchel C, Conrod P, Flor H, Garavan H, Gallinat J, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Nichols T, Lathrop M, Loth E, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Toro R, Schumann G, Paus T, Global genetic variations predict brain response to faces, PLOS Genetics, 10, (8), 2014, pe1004523 Journal Article, 2014 TARA - Full Text DOI

Goulden N, Khusnulina A, Davis NJ, Bracewell RM, Bokde AL, McNulty JP, Mullins PG, The salience network is responsible for switching between the default mode network and the central executive network: Replication from DCM, Neuroimage, 99, 2014, p180 - 190 Journal Article, 2014 DOI

Meyer BM, Huemer J, Rabl U, Boubela RN, Kalcher K, Berger A, Banaschewski T, Barker G, Bokde A, Büchel C, Conrod P, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Heinz A, Ittermann B, Jia T, Lathrop M, Martinot JL, Nees F, Rietschel M, Smolka MN, Bartova L, Popovic A, Scharinger C, Sitte HH, Steiner H, Friedrich MH, Kasper S, Perkmann T, Praschak-Rieder N, Haslacher H, Esterbauer H, Moser E, Schumann G, Pezawas L, Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults., Brain structure & function, 2014 Journal Article, 2014 TARA - Full Text DOI

Cavedo E, Lista S, Khachaturian Z, Aisen P, Amouyel P, Herholz K, Jack CR, Sperling R, Cummings J, Blennow K, O'Bryant S, Frisoni GB, Khachaturian A, Kivipelto M, Klunk W, Broich K, Andrieu S, de Schotten MT, Mangin JF, Lammertsma AA, Johnson K, Teipel S, Drzezga A, Bokde A, Colliot O, Bakardjian H, Zetterberg H, Dubois B, Vellas B, Schneider LS, Hampel H, The Road Ahead to Cure Alzheimer's Disease: Development of Biological Markers and Neuroimaging Methods for Prevention Trials Across all Stages and Target Populations., The journal of prevention of Alzheimer's disease, 1, (3), 2014, p181-202 Journal Article, 2014 DOI TARA - Full Text

Mothersill O, Morris DW, Kelly S, Rose EJ, Bokde A, Reilly R, Gill M, Corvin AP, Donohoe G, Altered medial prefrontal activity during dynamic face processing in schizophrenia spectrum patients, Schizophrenia research, 157, 2014, p225 - 230 Journal Article, 2014 DOI

Teipel, S.J. Grothe, M.J. Filippi, M. Fellgiebel, A. Dyrba, M. Frisoni, G.B. Meindl, T. Bokde, A.L.W. Hampel, H. Klöppel, S. Hauenstein, K., Fractional anisotropy changes in Alzheimer's disease depend on the underlying fiber tract architecture: A multiparametric DTI study using joint independent component analysis, Journal of Alzheimer's Disease, 41, (1), 2014, p69 - 83 Journal Article, 2014 DOI URL

Khan W, Giampietro V, Ginestet C, Dell'Acqua F, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaître H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A; IMAGEN consortium, No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents, Journal of Alzheimer's Disease, 40, (1), 2014, p37-43 Journal Article, 2014 TARA - Full Text DOI

Whelan R, Watts R, Orr CA, Althoff RR, Artiges E, Banaschewski T, Barker GJ, Bokde ALW, Büchel C, Carvalho FM, Conrod PJ, Flor H, Fauth-Bühler M, Frouin V, Gallinat J, Gan G, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Ortiz N, Paillère-Martinot ML, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Garavan H; IMAGEN Consortium, Neuropsychosocial profiles of current and future adolescent alcohol misusers., Nature, 512, (7513), 2014, p185 - 189 Journal Article, 2014 DOI TARA - Full Text

White TP, Loth E, Rubia K, Krabbendam L, Whelan R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Paillère ML, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T, Smolka MN, Shergill SS, Schumann G, Sex differences in COMT polymorphism effects on prefrontal inhibitory control in adolescence., Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39, (11), 2014, p2560-9 Journal Article, 2014 DOI TARA - Full Text

Nymberg C, Banaschewski T, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Klingberg T; IMAGEN consortium, DRD2/ANKK1 polymorphism modulates the effect of ventral striatal activation on working memory performance, Neuropsychopharmacology, 39, (10), 2014, p2357 - 2365 Journal Article, 2014 DOI TARA - Full Text

Loth E, Poline JB, Thyreau B, Jia T, Tao C, Lourdusamy A, Stacey D, Cattrell A, Desrivières S, Ruggeri B, Fritsch V, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Fauth-Buehler M, Flor H, Gallinat J, Garavan H, Heinz A, Bruehl R, Lawrence C, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Smolka M, Struve M, Feng J, Schumann G; IMAGEN Consortium, Oxytocin Receptor Genotype Modulates Ventral Striatal Activity , Biological Psychiatry, 76, (5), 2014, p367 - 376 Journal Article, 2014 DOI

Teipel, Stefan J. Flatz, Wilhelm Ackl, Nibal Grothe, Michel Kilimann, Ingo Bokde, Arun L. W. Grinberg, Lea Amaro jr, Edson Kljajevic, Vanja Alho, Eduardo Knels, Christina Ebert, Anne Heinsen, Helmut Danek, Adrian, Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus, Psychiatry Research: Neuroimaging, 221, (3), 2014, p187-194 Journal Article, 2014 TARA - Full Text DOI

Ciblis A, Butler ML, Bokde A, Mullins P, O'Neill D, McNulty J, Access to Neuroimaging in Dementia: A Survey of Specialists, Ir J Med Sci, Irish Gerontological Society, Galway, 10-11 Oct 2014, 183, (Suppl 7), 2014, ppS330 Meeting Abstract, 2014

Loth E, Poline J.-B, Thyreau B, Jia T, Tao C, Lourdusamy A, Stacey D, Cattrell A, Desrivières S, Ruggeri B, Fritsch V, Banaschewski T, Barker G.J, Bokde A.L.W, Büchel C, Carvalho F.M, Conrod P.J, Fauth-Buehler M, Flor H, Gallinat J, Garavan H, Heinz A, Bruehl R, Lawrence C, Mann K, Martinot J.-L, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Smolka M, Struve M, Feng J, Schumann G, Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events, Biological Psychiatry, 76, (5), 2014, p367 - 376 Journal Article, 2014 URL DOI

Castellanos-Ryan N, Struve M, Whelan R, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Flor H, Fauth-Bühler M, Frouin V, Gallinat J, Gowland P, Heinz A, Lawrence C, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Schumann G, Garavan H, Conrod PJ; The IMAGEN Consortium, Neural and Cognitive Correlates of the Common and Specific Variance Across Externalizing Problems in Young Adolescence, American Journal of Psychiatry, 171, (12), 2014, p1310-1319 Journal Article, 2014 DOI

Stringaris A, Castellanos-Ryan N, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Itterman B, Lawrence C, Nees F, Paillere-Martinot ML, Paus T, Pausova Z, Rietschel M, Smolka MN, Schumann G, Goodman R, Conrod P, Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample., Journal of child psychology and psychiatry, and allied disciplines, 55, (12), 2014, p1380-9 Journal Article, 2014 TARA - Full Text DOI

Kljajevic V, Meyer P, Holzmann C, Dyrba M, Kasper E, Bokde AL, Fellgiebel A, Meindl T, Hampel H, Teipel S, The ε4 genotype of apolipoprotein e and white matter integrity in Alzheimer's disease, Alzheimer's and Dementia, 10, (3), 2014, p401-404 Journal Article, 2014 DOI TARA - Full Text

Kilimann I, Grothe M, Heinsen H, Alho EJ, Grinberg L, Amaro E Jr, Dos Santos GA, da Silva RE, Mitchell AJ, Frisoni GB, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Teipel SJ, Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study, Journal of Alzheimer's Disease, 40, (3), 2014, p687 - 700 Journal Article, 2014 DOI TARA - Full Text

Dyrba, M, Ewers, M, Wegrzyn, M, Kilimann, I, Plant, C, Oswald, A, Meindl, T, Pievani, M, Bokde, ALW, Fellgiebel, A, Filippi, M, Hampel, H, Kloppel, S, Hauenstein, K, Kirste, T, Teipel, SJ, EDSD Study Grp, Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer's Disease Using Machine Learning Classification of Multicenter DTI Data, PLOS ONE, 8, (5), 2013 Journal Article, 2013 DOI TARA - Full Text

Balsters JH, O'Connell RG, Galli A, Nolan H, Greco E, Kilcullen SM, Bokde AL, Lai R, Upton N, Robertson IH, Changes in resting connectivity with age: A simultaneous electroencephalogram and functional magnetic resonance imaging investigation., Neurobiology of Aging, 34, (9), 2013, p2194 - 2207 Journal Article, 2013 TARA - Full Text DOI

Bede, P, Bokde, ALW, Byrne, S, Elamin, M, McLaughlin, RL, Kenna, K, Fagan, AJ, Pender, N, Bradley, DG, Hardiman, O, Multiparametric MRI study of ALS stratified for the C9orf72 genotype, NEUROLOGY, 81, (4), 2013, p361-369 Journal Article, 2013 DOI

P. Bede, A. Bokde, M. Elamin, S. Byrne, R.L. McLaughlin, N. Jordan, H. Hampel, L. Gallagher, C. Lynch, A.J. Fagan, N. Pender, O. Hardiman, Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality, Journal of Neurology, Neurosurgery & Psychiatry, 84, (7), 2013, p766 - 773 Journal Article, 2013 DOI

Teipel SJ, Sabri O, Grothe M, Barthel H, Prvulovic D, Buerger K, Bokde AL, Ewers M, Hoffmann W, Hampel H, Perspectives for multimodal neurochemical and imaging biomarkers in Alzheimer's disease., Journal of Alzheimer's disease : JAD, 33 Suppl 1, 2013, pS329-47 Journal Article, 2013 DOI TARA - Full Text

Lee NC, Krabbendam L, White TP, Meeter M, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Heinz A, Garavan H, Gowland P, Ittermann B, Mann K, Paillère Martinot ML, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T, Fauth-Bühler M, Smolka MN, Gallinat J, Schumann G, Shergill SS, Do you see what I see? Sex differences in the discrimination of facial emotions during adolescence, Emotion, 13, (6), 2013, p1030 - 1040 Journal Article, 2013 DOI

Kehoe EG, Toomey JM, Balsters JH, Bokde AL., Healthy aging is associated with increased neural processing of positive valence but attenuated processing of emotional arousal: an fMRI study, Neurobiology of Aging, 34, (3), 2013, p809-821 Journal Article, 2013 TARA - Full Text DOI

Teipel, SJ, Wegrzyn, M, Meindl, T, Frisoni, G, Bokde, ALW, Fellgiebel, A, Filippi, M, Hampel, H, Kloppel, S, Hauensteink, K, Ewers, M, EDSD Study Grp, Anatomical MRI and DTI in the Diagnosis of Alzheimer's Disease: A European Multicenter Study, JOURNAL OF ALZHEIMERS DISEASE, 31, 2012, pS33-S47 Journal Article, 2012 DOI

Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Petersen RC, Jack CR Jr, Feldman HH, Bokde AL, Alexander GE, Scheltens P, Vellas B, Dubois B, Weiner M, Hampel H; North American Alzheimer's Disease Neuroimaging Initiative (ADNI)., Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance., Neurobiology of Aging, 33, (7), 2012, p1203 - 1214 Journal Article, 2012 DOI

Kehoe EG, Toomey JM, Balsters JH, Bokde ALW, Personality modulates the effects of emotional arousal and valence on brain activation, Social, Cognitive and Affective Neuroscience, 7, (7), 2012, p858 - 870 Journal Article, 2012 DOI

Teipel SJ, Wegrzyn M, Meindl T, Frisoni G, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Ewers M, Anatomical MRI and DTI in the Diagnosis of Alzheimer's Disease: A European Multicenter Study, Journal of Alzheimer's Disease, 2012 Journal Article, 2012

Rose EJ, Morris DW, Fahey C, Robertson IH, Greene C, O'Doherty J, Newell FN, Garavan H, McGrath J, Bokde A, Tropea D, Gill M, Corvin AP, Donohoe G., The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function., Twin Research and Human Genetics, 15, (3), 2012, p296 - 303 Journal Article, 2012 TARA - Full Text DOI

Koch W, Teipel S, Mueller S, Benninghoff J, Wagner M, Bokde AL, Hampel H, Coates U, Reiser M, Meindl T., Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease., Neurobiological Aging, 33, (3), 2012, p466-478 Journal Article, 2012 TARA - Full Text

Stacey D, Bilbao A, Maroteaux M, Jia T, Easton AC, Longueville S, Nymberg C, Banaschewski T, Barker GJ, Büchel C, Carvalho F, Conrod PJ, Desrivières S, Fauth-Bühler M, Fernandez-Medarde A, Flor H, Gallinat J, Garavan H, Bokde AL, Heinz A, Ittermann B, Lathrop M, Lawrence C, Loth E, Lourdusamy A, Mann KF, Martinot JL, Nees F, Palkovits M, Paus T, Pausova Z, Rietschel M, Ruggeri B, Santos E, Smolka MN, Staehlin O, Jarvelin MR, Elliott P, Sommer WH, Mameli M, Müller CP, Spanagel R, Girault JA, Schumann G, RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release., Proceedings of the National Academy of Sciences of the United States of America, 109, (51), 2012, p21128-33 Journal Article, 2012 DOI

Bartley M, Bokde AL, Ewers M, Faluyi YO, Tobin WO, Snow A, Connolly J, Delaney C, Coughlan T, Collins DR, Hampel H, O'Neill D, Subjective memory complaints in community dwelling healthy older people: the influence of brain and psychopathology., International Journal of Geriatric Psychiatry, 27, (8), 2012, p836-43 Journal Article, 2012 DOI

Emma J. Rose, Ciara Greene, Sinead Kelly, Derek W. Morris, Ian H. Robertson, Ciara Fahey, Sarah Jacobson, John O'Doherty, Fiona N. Newell, Jane McGrath, Arun Bodke, Hugh Garavan, Thomas Frodl, Michael Gill, Aiden P. Corvin, Gary Donohoe, The NOS1 variant rs6490121 is associated with variation in prefrontal function and gray matter density in healthy individuals, NeuroImage, 60, (1), 2012, p614-622 Journal Article, 2012 TARA - Full Text

O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins R, Coughlan T, Prvulovic D, Hampel H, Sexual Dimorphism in Healthy Aging and Mild Cognitive Impairment: A DTI Study., PloS one, 7, (7), 2012, pe37021 Journal Article, 2012 DOI TARA - Full Text

Fischer FU, Scheurich A, Wegrzyn M, Schermuly I, Bokde AL, Kloeppel S, Pouwels PJ, Teipel S, Yakushev I, Fellgiebel A, Automated tractography of the cingulate bundle in Alzheimer's disease: a multi-center DTI study, Journal of Magnetic Resonance Imaging, 36, (1), 2012, p84 - 91 Journal Article, 2012 DOI

Soldner J, Meindl T, Koch W, Bokde AL, Reiser MF, Möller HJ, Bürger K, Hampel H, Teipel SJ., [Structural and functional neuronal connectivity in Alzheimer's disease : A combined DTI and fMRI study.], Nervenartz, 83, (7), 2012, p878 - 887 Journal Article, 2012 DOI

Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O'Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O, Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study., Lancet neurology, 11, (3), 2012, p232-40 Journal Article, 2012 DOI

Bede P, Bokde AL, Byrne S, Elamin M, Fagan AJ, Hardiman O, Spinal cord markers in ALS: Diagnostic and biomarker considerations., Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 13, (5), 2012, p407-15 Journal Article, 2012 DOI

O'Connell RG, Balsters JH, Kilcullen SM, Campbell W, Bokde AW, Lai R, Upton N, & Robertson IH, A simultaneous ERP/fMRI investigation of the P300 aging effect., Neurobiology of Aging, 33, (10), 2012, p2448 - 2461 Journal Article, 2012 DOI

O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins DR, Coughlan T, Prvulovic D, Hampel H, Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment., PloS one, 7, (2), 2012, pe32441 Journal Article, 2012 TARA - Full Text DOI

Laurence O'Dwyer, Franck Lamberton, Arun L. W. Bokde, Michael Ewers, Yetunde O. Faluyi, Colby Tanner, Bernard Mazoyer, Des O'Neill, Máiréad Bartley, D. Rónán Collins, Tara Coughlan, David Prvulovic, Harald Hampel, Multiple Indices of Diffusion Identifies White Matter Damage in Mild Cognitive Impairment and Alzheimer's Disease, PLoS One, 6, (6, e21745), 2011 Journal Article, 2011 TARA - Full Text

F. Geser, L. O'Dwyer, O. Hardiman, P. Bede, A.L.W. Bokde, D. Prvulovic, John Q. Trojanowski, H. Hampel, On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia, Progress in Neurobiology, 95, (4), 2011, p649-662 Journal Article, 2011 TARA - Full Text

Frodl T, Scheuerecker J, Schoepf V, Linn J, Koutsouleris N, Bokde AL, Hampel H, Möller HJ, Brückmann H, Wiesmann M, Meisenzahl E., Different effects of mirtazapine and venlafaxine on brain activation: an open randomized controlled fMRI study, Journal of Clinical Psychiatry, 72, (4), 2011, p448-57 Journal Article, 2011 DOI

Joshua H. Balsters, Redmond G. O'Connell, Mary P. Martin, Alessandra Galli, Sarah M. Cassidy, Sophia M. Kilcullen, Sonja Delmonte, Sabina Brennan, Jim F. Meaney, Andrew J. Fagan, Arun L. W. Bokde, Neil Upton, Robert Lai, Marc Laruelle, Brian Lawlor, Ian H. Robertson, Donepezil Impairs Memory in Healthy Older Subjects: Behavioural, EEG and Simultaneous EEG/fMRI Biomarkers, PLoS ONE, 6, (9), 2011, pe24126 Journal Article, 2011 TARA - Full Text

O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins DR, Coughlan T, Prvulovic D, Hampel H, Using Diffusion Tensor Imaging and Mixed-Effects Models to Investigate Primary and Secondary White Matter Degeneration in Alzheimer's Disease and Mild Cognitive Impairment., Journal of Alzheimer's disease : JAD, 26, (4), 2011, p667 - 682 Journal Article, 2011 DOI

Kognitionsbezogene Interventionen bei leichter kognitiver Beeintraechtigung [Cognitive Training in Mild Cognitive Impaired Subjects] in, editor(s)J. Haberstroh and J. Pantel , Demenz psychosozial behandeln, Heidelberg, AKA Verlag, 2011, pp79 - 90, [Buschert VC, Bokde ALW, Hampel H] Book Chapter, 2011

Carballedo A, Scheuerecker J, Meisenzahl E, Schoepf V, Bokde A, Möller HJ, Doyle M, Wiesmann M, Frodl T, Functional connectivity of emotional processing in depression, Journal of Affective Disorders, 2011 Journal Article, 2011

Bartley M, Bokde A, O'Neill D, Mild Cognitive Impairment, NEJM, 365, (14), 2011, p1357 - 1358 Journal Article, 2011

Bede P, Bokde AL, Byrne SC, Elamin M, Walsh RJ, Hardiman O, Waterskier's Hirayama syndrome, Journal of Neurology, 258, (11), 2011, p2078 - 2079 Journal Article, 2011 DOI

Hampel H, Prvulovic D, Teipel SJ, Bokde AL, Recent developments of functional magnetic resonance imaging research for drug development in Alzheimer's disease, Progress in Neurobiology, 95, (4), 2011, 570-578 Journal Article, 2011 URL TARA - Full Text DOI

David Prvulovic, Arun L.W. Bokde, Frank Faltraco, Harald Hampel, Functional magnetic resonance imaging as a dynamic candidate biomarker for Alzheimer's disease., Progress in Neurobiology, 95, (4), 2011, p557-569 Journal Article, 2011 TARA - Full Text

Claudia Plant, Stefan J. Teipel, Annahita Oswald, Christian Böhm, Thomas Meindl, Janaina Mourao-Miranda, Arun W. Bokde, Harald Hampel and Michael Ewers, Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease , NeuroImage, 50, (1), 2010, p162 - 174 Journal Article, 2010 TARA - Full Text DOI

Bokde ALW, Lopez-Bayo P, Born C, Ewers M, Meindl T, Teipel SJ, Faltraco F, Reiser M, Moeller H-J, Hampel H, Functional Abnormalities in the Dorsal Visual Pathway in Alzheimer's Disease Patients, Radiology, 254, (1), 2010, p219 - 226 Journal Article, 2010 DOI

M. Bartley, Y. Faluyi, W.O. Tobin, A. Snow, J. Connolly, C. Delaney, M. Ewers, R. Collins, T. Coughlan, A. Bokde, H. Hampel, D. O'Neill, Subjective memory complaints are associated with affective disorders but not white matter hyperintensities in a sample of community dwelling healthy older people, European Geriatric Medicine, 6th Congress European Union Geriatric Medicine Society, Dublin, 2010, 1, 2010, ppB176 - B176 Meeting Abstract, 2010

Koch W, Teipel SJ, Mueller S, Buerger K, Bokde ALW, Hampel H, Coates U, Reiser M, Meindl T, Effects of aging on default mode network activity in resting state fMRI: Does the method of analysis matter? , NeuroImage, 51, (1), 2010, p280-287 Journal Article, 2010 DOI

Hampel H, Frank R, Broich K, Teipel SJ, Katz RG, Hardy J, Herholz K, Bokde ALW, Jessen F, Hoessler YC, Sanhai WR, Zetterberg H, Woodcock J, Blennow K, Biomarkers for diagnosis and as endpoints for clinical trials in Alzheimer's disease, Nature Reviews: Drug Discovery, 9, 2010, p560-574 Journal Article, 2010 DOI

Gutyrchik E, Churan J, Meindl T, Bokde ALW, von Bernewitz H, Born C, Reiser MF, Poeppel E, Wittman M , Functional imaging of duration discrimination on two different time scales, Neuroscience Letters, 469, (3), 2010, p411 - 415 Journal Article, 2010 DOI

Buschert V, Bokde ALW, Hampel H, Cognitive Intervention in Alzheimer's Disease, Nature Reviews Neurology, 6, (9), 2010, p508 - 517 Journal Article, 2010 DOI

Stefan J. Teipel, Arun L.W. Bokde, Thomas Meindl, Edson Amaro Jr., Jasmin Soldner, Maximilian F. Reiser, Sabine C. Herpertz, Hans-Jürgen Möller and Harald Hampel, White matter microstructure underlying default mode network connectivity in the human brain , NeuroImage, 49, (3), 2010, p2021 - 2032 Journal Article, 2010 TARA - Full Text DOI

Bokde ALW, Karmann M, Born C, Teipel SJ, Omerovic M, Ewers M, Frodl T, Meisenzahl E, Reiser MF, Moeller HJ, Hampel H, Altered Brain Activation During a Verbal Working Memory Task in Subjects with Amnestic Mild Cognitive Impairment., Journal of Alzheimer's Disease, 21, (1), 2010, p103-118 Journal Article, 2010 DOI TARA - Full Text

Bokde ALW, Karmann M,Teipel SJ, Born C, Lieb M, Reiser M, Moeller H-J, Hampel H, Decreased activation along the dorsal visual pathway after a 3-month treatment with Galantamine in mild Alzheimer's disease, Journal of Clinical Psychopharmacology, 29, (2), 2009, p147 - 156 Journal Article, 2009 DOI

Arun L.W. Bokde, Michael Ewers and Harald Hampel, Assessing neuronal networks: Understanding Alzheimer's disease, Progress in Neurobiology, 89, (2), 2009, p125 - 133 Journal Article, 2009 DOI TARA - Full Text

Bokde ALW, Lopez-Bayo P, Born C, Dong W, Meindl T, Leinsinger G, Teipel SJ, Faltraco F, Reiser MF, Möller H-J, Hampel H, Functional abnormalities of the visual processing system in subjects with mild cognitive impairment: an fMRI study, Psychiatry Research - Neuroimaging, 163, (3), 2008, p248 - 259 Journal Article, 2008 DOI

Hampel H, Buerger K, Teipel SJ, Bokde ALW, Zetterberg H, Blennow K. , Core candidate neurochemical and imaging biomarkers of Alzheimer's disease., Alzheimer's & Dementia, 4, (1), 2008, p38-48 Journal Article, 2008 DOI

Teipel SJ, Bokde ALW, Born C, Meindl T, Reiser MF, Möller H-J, Hampel H, Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study, Brain, 130, (7), 2007, p1745 - 1758 Journal Article, 2007 DOI

Teipel SJ, Born C, Ewers M, Bokde AL, Reiser MF, Möller HJ, Hampel H, Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment, Neuroimage, 38, (1), 2007, p13 - 24 Journal Article, 2007 DOI

Leinsinger G, Born C, Meindl T, Bokde ALW, Britsch S, Lopez-Bayo P, Teipel SJ, Möller H-J, Hampel H, Reiser MF, Age-dependent differences in human brain activity using a face- and location-matching task: an fMRI study, Dementia and Geriatric Cognitive Disorders, 24, (4), 2007, p235 - 246 Journal Article, 2007 DOI

Teipel SJ, Stahl R, Dietrich O, Schoenberg SO, Perneczky R, Bokde AL, Reiser MF, Möller HJ, Hampel H, Multivariate network analysis of fiber tract integrity in Alzheimer's disease, Neuroimage, 34, (3), 2007, p985 - 995 Journal Article, 2007 DOI

Bokde ALW, Lopez-Bayo P, Meindl T, Pechler S, Born C, Faltraco F, Teipel SJ, Möller H-J, Hampel H, Functional connectivity of the fusiform gyrus during a face matching task in subjects with mild cognitive impairment, Brain, 129, (5), 2006, p1113 - 1124 Journal Article, 2006 DOI

Teipel SJ, Flatz WH, Heinsen H, Bokde ALW, Schoenberg SO, Stöckel S, Dietrich O, Reiser MF, Möller HJ, Hampel H, Measurement of basal forebrain atrophy in Alzheimer's disease using MRI, Brain, 128, (11), 2005, p2626 - 2644 Journal Article, 2005 DOI

Bokde AL, Teipel SJ, Schwarz R, Leinsinger G, Buerger K, Moeller T, Möller HJ, Hampel H, Reliable manual segmentation of the frontal, parietal, temporal, and occipital lobes on magnetic resonance images of healthy subjects, Brain Research, 14, (3), 2005, p135 - 145 Journal Article, 2005 DOI

Bokde ALW, Dong W, Born C, Leinsinger G, Meindl T, Teipel SJ, Reiser M, Hampel H, Task difficulty in a simultaneous face matching task modulates activity in face fusiform area, Cognitive Brain Research, 25, (3), 2005, p701 - 710 Journal Article, 2005 DOI

Mourão-Miranda J, Bokde ALW, Born C, Hampel H, Stetter M, Classifying brain states and determining the discriminating volume between them: support vector machine on functional MRI data, Neuroimage, 28, (4), 2005, p980 - 995 Journal Article, 2005 DOI

Bokde ALW, Teipel SJ, Drzezga A, Thissen J, Bartenstein P, Dong W, Leinsinger G, Born C, Schwaiger M, Moeller HJ, Hampel H, Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease, Dementia and Geriatric Cognitive Disorders, 20, (6), 2005, p352 - 357 Journal Article, 2005 DOI

Ibáñez V, Pietrini P, Furey ML, Alexander GE, Millet P, Bokde AL, Teichberg D, Schapiro MB, Horwitz B, Rapoport SI., Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy., Brain Research Bulletin, 63, (2), 2004, p147 - 154 Journal Article, 2004 DOI

Podruchny TA, Connolly C, Bokde A, Herscovitch P, Eckelman WC, Kiesewetter DO, Sunderland T, Carson RE, Cohen RM., In vivo muscarinic 2 receptor imaging in cognitively normal young and older volunteers, Synapse, 48, (1), 2003, p39 - 44 Journal Article, 2003 DOI

Cohen RM, Podruchny TA, Bokde AL, Carson RE, Herscovitch P, Kiesewetter DO, Eckelman WC, Sunderland T., Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-epsilon4 allele, Synapse, 49, (3), 2003, p150 - 156 Journal Article, 2003 DOI

Teipel SJ, Bayer W, Alexander GE, Bokde AL, Zebuhr Y, Teichberg D, Müller-Spahn F, Schapiro MB, Möller HJ, Rapoport SI, Hampel H., Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration, Neurobiology of Aging, 24, (1), 2003, p85 - 94 Journal Article, 2003 DOI

Bokde AL, Teipel SJ, Zebuhr Y, Leinsinger G, Gootjes L, Schwarz R, Buerger K, Scheltens P, Moeller HJ, Hampel H., A new rapid landmark-based regional MRI segmentation method of the brain, Journal of Neurological Sciences, 194, (1), 2002, p35 - 40 Journal Article, 2002 DOI

Rosen AC, Bokde AL, Pearl A, Yesavage JA., Ethical, and practical issues in applying functional imaging to the clinical management of Alzheimer's disease, Brain and Cognition, 50, (3), 2002, p498 - 519 Journal Article, 2002 DOI

Giovacchini G, Chang MC, Channing MA, Toczek M, Mason A, Bokde AL, Connolly C, Vuong BK, Ma Y, Der MG, Doudet DJ, Herscovitch P, Eckelman WC, Rapoport SI, Carson RE., Brain incorporation of [11C]arachidonic acid in young healthy humans measured with positron emission tomography, Journal of Cerebral Blood Flow & Metabolism , 22, (12), 2002, p1453 - 1462 Journal Article, 2002 DOI

Bokde AL, Pietrini P, Ibáñez V, Furey ML, Alexander GE, Graff-Radford NR, Rapoport SI, Schapiro MB, Horwitz B., The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease, Archives of Neurology, 58, (3), 2001, p480 - 486 Journal Article, 2001 URL

Bokde ALW, Tagamets M-A, Friedman RB, Horwitz B, Functional interactions of the inferior frontal cortex during the processing of words and word-like stimuli, Neuron, 30, (2), 2001, p609 - 617 Journal Article, 2001 DOI

Bokde, A.L.W., Tagamets, M.-A., Friedman, R.B., Horwitz, B., FMRI functional connectivity of the inferior frontal gyrus, 11, (5), 2000, ppS294 Meeting Abstract, 2000

Bokde ALW, Lueptow RM & Abraham B, Spanwise structure of wall pressure on a cylinder in axial flow, Physics of Fluids, 11, (1), 1999, p151 - 161 Journal Article, 1999 TARA - Full Text

Bokde, A.L.W., Ibáñez, V., Pietrini, P., Furey, M.L., Alexander, G.E., Graff-Radford, N.R., Rapoport, S.I., (...), Horwitz, B., Cerebral glucose hypometabolism in the visual variant of Alzheimer's disease after correcting for brain atrophy, NeuroImage, 7, (4), 1998, pS628 Journal Article, 1998

Research Expertise

Description

Arun Bokde investigates how large-scale brain networks function and how they are associated with both normal cognition, such as memory and attention, and breakdowns that lead to brain disorders. There are two populations of interest, young people and older people. Bokde uses functional magnetic resonance imaging to measure brain activation during visual perceptual tasks, as well as working memory tasks in persons with mild cognitive impairment, patients with Alzheimer's disease (AD), and healthy participants. These studies provide an understanding of how disease affects not only memory networks, but also perceptual processes in the brain. Recent findings were the basis of a new approach to testing AD-related drugs. In addition, Bokde has investigated the structural integrity of brain networks using diffusion imaging in combination with tractography in the limbic system, a network associated with memory function and profoundly affected in patients with AD. Bokde has also led an international project to develop training resources for the application of neuroimaging to the diagnostic process of AD patients, as well as developing resources for patients and their families to gain a better understanding of the disease. Bokde is co-PI (Ireland) for the the IMAGEN study, which is the first multicentre functional and structural genetic-neuroimaging study of a cohort of 2000 +14 year old adolescents. Cognitive, behavioural, clinical and neuroimaging data from the adolescents and their families and teachers have been gathered and the participants have been followed-up for 9 years - the third follow-up investigation is on-going. Bokde is investigating how stress modulates the development of brain networks, both within the thin cortical grey matter layer and the white matter regions that contain the 'cables' of the brain networks. The studies have been until now cross-sectional in nature and with new longitudinal data Bokde will start investigation of the interaction among stress, biological and genetic factors contributing to mental health disorders. He has close, long-standing collaborations with clinicians at St James's Hospital, Tallaght Hospital, and St Patrick's University Hospital. The collaborations enhance the communication and translation of research into the clinical context as well as feedback into research activities.

Projects

  • Title
    • Effects of Brain Training in Older Healthy Subjects
  • Summary
    • Executive function (EF) is a neurocognitive umbrella term for skills such as planning, working memory, impulse control, inhibition, and mental flexibility. Normal aging is characterised by declines in EF. The proposed integrated executive function adaptive training task specifically trains multiple components of the brain's executive function system simultaneously.
  • Funding Agency
    • SFI, HEA
  • Date From
    • May 2010
  • Date To
    • Dec 2011
  • Title
    • The application of magnetic resonance imaging to the study of memory processes in young and older healthy adults, and older adults with mild cognitive impairment.
  • Summary
    • In general emotional events are remembered better than non-emotional ones. Many neuroimaging studies have suggested that the encoding of emotionally arousing stimuli into declarative memory relies upon the activation of the amygdala and the hippocampus. Outlined in the seminal work of Osgood, Suci and Tannenbaum a half century ago (1957) were the basic parameters of emotion- hedonic valence and arousal. The authors conducted a factor analysis of the verbal descriptions individuals ascribe to objects, reducing them to three different dimensions, namely valence, arousal and dominance, and it is the latter two of the three that have since been consistently shown to differentiate emotional value. Valence refers to the pleasantness or unpleasantness of a stimulus- the appetitive or defensive motivation; while arousal generally refers to its excitability or the strength of the motivating factor- its potential to illicit a behavioural response. In this study the focus will be on which of the two factors, valence or arousal, contributes more greatly to the enhancement of memory by emotion, and whether they are supported by the same or different brain areas.
  • Funding Agency
    • HRB, SFI
  • Date From
    • June 2009
  • Date To
    • September 2011
  • Title
    • Neuronal Coordination
  • Funding Agency
    • Goverment of State of Hesse, Germany
  • Date From
    • Sept 2010
  • Date To
    • Aug 2015
  • Title
    • Exist-Seed: Software development for measurement of the effects of cultural influences through functional magnetic resonance imaging
  • Summary
    • Investigation of the effects of culturally significant stimuli. Investigation of design optimization for functional magnetic resonance imaging studies.
  • Funding Agency
    • German Ministry of Education and Research (Bonn, Germany) and the European Social Funds (Brussels, B
  • Date From
    • Sept 2005
  • Date To
    • August 2006
  • Title
    • Diagnosis of Alzheimer's disease using machine learning algorithms
  • Summary
    • Development and application of machine learning methods for discrimination of Alzheimer's disease patients and healthy subjects.
  • Funding Agency
    • Hirnliga (Nuermbrecht, Germany)
  • Date From
    • Jan 2007
  • Date To
    • Dec 2007
  • Title
    • Cholinergic modulation of the cortical response to neuropsychological activation during pharmacological fMRI: visual attention
  • Summary
    • Investigation of the effects of rivastigmine in mild cognitive impaired subjects in a double-blind placebo controlled pharmacological study.
  • Funding Agency
    • Novartis GmbH (Nuremberg, Germany)
  • Date From
    • Sept 2003
  • Date To
    • Jan 2007
  • Title
    • Cholinergic modulation of the cortical response to neuropsychological activation during pharmacological MRI in patients with dementia of the Alzheimer type: Attention paradigm
  • Summary
    • Investigation of the effects of Galatamine in Alzheimer dissease patients after three months treatment. Development of funcitonal magnetic resonance imaging based markers for measureing effectivity of cholinergic treatment.
  • Funding Agency
    • Janssen-Cilag GmbH (Neuss, Germany)
  • Date From
    • Feb 2004
  • Date To
    • June 2007
  • Title
    • New Method for analysis of dynamic cognitive networks
  • Summary
    • Development of functional connectivity methods for application to functional magnetic resonance imaging data. Study of ageing effects on visual perception and the interaction among the networks utilized for perception.
  • Funding Agency
    • Volkswagen Foundation (Hannover, Germany)
  • Date From
    • Jan 2002
  • Date To
    • Jan 2006

Keywords

Age related diseases; Ageing, memory and other cognitive processes; Ageing, stroke, dementia; Alzheimer's disease; Biostatistical methods; Development, prevention and treatment of mental disease or disorder; Human Learning and Memory; Imaging Techniques; Imaging, image processing; Neurodegeneration; Neurogenetics; Neuropharmacology; Neuropsychology; Psychiatry; Vision

Recognition

Representations

Dementia and Neurodegeneration Network Ireland (DNNI) Multidisciplinary Consensus Panel since 2017

Reviewer for scientific journals and grant applications. since 2000

2015 Discover Science Night. 25-Sep-2015

2014 Discover Science Night. 26-Sep-2014

Co-Lead of Organizing Committee for workshop 'Neuroimaging in Dementia' May 2013

Co-Lead of Organizing Committee for workshop 'Application of neuroimaging in Alzheimer's disease' July 2013

Co-Lead of Organizing Committee for workshop 'Application of neuroimaging in Alzheimer's disease' September 2013

Co-Lead of Organizing Committee for workshop 'Introduction to theory and application of neuroimaging' September 2014

Co-Lead of Organizing Committee for workshop 'Neuroimaging - Theory and Practical Course' June 2015

Awards and Honours

Sigma Gamma Tau, Member 1987

Memberships

Society of Neuroscience (USA) 1998

German Society for Neuroscience 2001

Organization of Human Brain Mapping 2002

Neuroscience Ireland 2014


Last updated 23 November 2016 School Web Administrator (Email).