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Research Projects

The academic staff members in Physiology run active research programmes, with laboratories based in the Trinity Biomedical Sciences Institute, the Trinity College Institute of Neuroscience, Lloyd Building, and the Watts Building. Some of the research projects ongoing are listed below. Feel free to contact us for further information.

Research Group DiseaseMechanismsTherapies
Kumlesh Dev
Drug Development Research Group
Krabbes Disease & novel therapies Demyelination & Neuroinflammation Astrocytes as drug targets
Alzheimer's Disease & drug development S1P Receptors as drug targets Drug Development: Discovery to market
Eric Downer
Translational Neuroimmunology Research Group
Multiple Sclerosis & drug development Neuropathic orofacial pain Cannabinoid Therapeutics
Multiple Sclerosis & exercise Innovative teaching strategies Cannabinoid pharmacology
Mikel Egana
Human Exercise Physiology Research Group
Cardiovascular Health Exercise tolerance and ageing Recovery exercise performance
Type 2 diabetes & exercise tolerance Oxygen uptake response to exercise Circulation and muscle fatigue
Aine Kelly
Kelly Lab
Alzheimer's Disease & Exercise BDNF & TrkB neuronal signaling Preventing age-related cognitive decline
Exercise, cognition & neuroprotection Biomarkers of concussion in sport Exercise as an anti-inflammatory
Veronica Campbell
Lab
Alzheimer's disease Neurodegenerative pathways Cannabinoid Pharmacology
Osteoarthritis Tissue engineering & adult stem cell biology Cannabinoid Pharmacology; Novel Scaffolds
Maeve Caldwell
Stem Cell Biology Research Group
Parkinson's disease and neuroprotection Animal & neuronal/glial human cell models MANF and CDNF
Alzheimer's disease Astrocytes: role in neuronal cell death APOE genotypes
Deirdre Edge
Edge Lab
Central pathology in mdx mice Exploring the respiratory network Beyond muscle targets
mdx respiratory muscle remodeling Fibre type distribution and inflammation Anti-inflammatory approaches
Alice Witney
Sensorimotor Neuromodulation Lab
Motor learning in health and disease Modifying neuronal excitability using TMS, tACS, tDCS Non-invasive neurostimulation protocols
Quantitative Sensory Testing for Pain Optogenetics in the teaching laboratory Posture and balance interventions
Marina Lynch
Neuroinflammation Research Group
Alzheimer's Disease Neuroinflammation Infiltrating cells Modulatio of the Inflammasome & BBB
Age-related neurodegeneration Microglial activation Anti-inflammatory strategies