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Student Centred Learning - Second Med Pharmacology

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Cardiovascular System

By the end of these lectures, the student should be able to:

  • appreciate the distribution and classification of adrenoceptors
  • know the potential sites for interfering with adrenergic neurotransmission and the functional consequences of their modulation
  • know and understand the mechanisms by which drugs selectively modulate adrenergic neurotransmission
  • understand the electrophysiological basis of common arrhythmias
  • know and understand the mechanisms of action of antiarrhythmic agents
  • understand and explain the mechanisms of action of cardiac glycosides and phosphodiesterase inhibitors with regard to cardiac contraction
  • appreciate adverse effects of cardiac glycosides and phosphodiesterase inhibitors
  • Understand the importance of nitric oxide and the effects of its manipulation on the vascular wall.
  • Appreciate the diversity among the vasodilators in terms of mechanism of action, clinical uses and adverse effects.

Last updated 21 September 2016 oneillm1@tcd.ie (Email).