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Laura Mc Cullagh
Associate Professor, Pharmacology & Therapeutics

Biography

In January 2016, Laura was appointed to the post of Associate Professor of Pharmacoeconomics & Health Technology Assessment. Laura graduated from the Sunderland School of Pharmacy (First Class Hons). She holds a PhD from the Department of Pharmacology & Therapeutics, Trinity College Dublin, for her research which focused on Health Technology Assessment within the Irish Healthcare Setting. Subsequent to this, Laura was appointed as a Health Research Board (ICE) Research Fellow working with the Cancer Pharmacoepidemiology and Pharmacoeconomics (CAPPE) Research Group. Research interests to date include pharmacoeconomic evaluation, value of information analysis, multiple criteria decision analysis, survival analysis, cost of care studies and analysis of drug utilisation and expenditure in the real world setting. Laura has been a member of the National Centre for Pharmacoeconomics (NCPE) Review Group for economic evaluations since 2008. In this capacity, Laura has been the lead author on over 25 Reports detailing the Pharmacoeconomics Evaluation of drugs submitted to the NCPE for evaluation prior to a reimbursement decision being made by the HSE. Previous roles have included Chief II Pharmacist in St James's Hospital, Dublin and Senior Medicines Information Pharmacist, Oxford Radcliffe Trust, UK.

Publications and Further Research Outputs

Peer-Reviewed Publications

McCullagh L, Schmitz S, Barry M, Walsh C, Examining the Feasibility and Utility of Estimating Partial Expected Value of Perfect Information (via a Nonparametric Approach) as Part of the Reimbursement Decision-Making Process in Ireland: Application to Drugs for Cancer, PharmacoEconomics, 2017 Journal Article, 2017 DOI

Corcoran A, Hickey N, Barry M, Usher C, McCullagh L, Ivacaftor for cystic fibrosis; An evaluation of real world utilisation and expenditure in the Irish Healthcare Setting., Irish Medical Journal, 110, (8), 2017 Journal Article, 2017 URL

Schmitz S, McCullagh L, Adams R, Walsh C, Identifying and Revealing the Importance of Decision-Making Criteria for Health Technology Assessment: A Retrospective Analysis of Reimbursement Recommendations in Ireland, PharmacoEconomics, 2016 Journal Article, 2016

Spillane S, McCullagh L, Barry M, Usher C, Analysis of Pharmacy Claims for High Cost Oncology Products: Abiraterone and Enzalutamide Usage in Mcrpc in Ireland, Value Health, 19, (7), 2016, ppA754 - A754 Poster, 2016

Ermisch M, Bucsics A, Vella Bonanno P, Arickx F, Bybau A, Bochenek T, van de Casteele M, Diogene E, Fürst J, Garuolien" K, van der Graaff M, Gulbinovi" J, Haycox A, Jones J, Joppi R, Laius O, Langner I, Martin AP, Markovic-Pekovic V, McCullagh L, Payers' Views of the Changes Arising through the Possible Adoption of Adaptive Pathways., 2016 Journal Article, 2016

O'Donnell H, McCullagh L, Barry M, The Potential Budget Impact of PCSK9 Inhibitors in Ireland, Value Health, 2016, 7, (19), 2016, ppA643 - A643 Poster, 2016

Morgan RB, McCullagh L, Barry M, Daly C, The cost of inpatient management of heart failure patients: a microcosting study in the Irish healthcare setting., 2016 Journal Article, 2016

McCullagh L, Barry M, The Pharmacoeconomic Evaluation Process in Ireland, PharmacoEconomics, 34, (12), 2016, p1267 - 1276 Journal Article, 2016

Gorry C, McCullagh M, Barry M, Drug Utilisation of Braf Inhibitors for Melanoma in Ireland, Value Health, 19, (7), 2016, ppA728 - A728 Poster, 2016

Dolan E, Schmitz S, Barry M, McCullagh L, Movement of Drugs for Cancer Through The Pharmacoeconomic Evaluation Process in Ireland: Consideration Given to The Quality of Clinical Evidence, Value Health, 2016, 19, (7), 2016, ppA757 - A757 Poster, 2016

Schmitz S, McCullagh L, Dolan E, Walsh C, The Quev Score: A Quantitative Evaluation of the Quality of Clinical Evidence in HTA, Value Health, 19, (7), 2016, ppA499 - A499 Poster, 2016

Godman B, Malmström RE, Diogene E, Gray A, Jayathissa S, Timoney A, Acurcio F, Alkan A, Brzezinska A, Bucsics A, Campbell SM, Czeczot J, de Bruyn W, Eriksson I, Yusof FA, Finlayson AE, Fürst J, Garuoliene K, Guerra Júnior A, Gulbinovi, J, Are new models needed to optimize the utilization of new medicines to sustain healthcare systems?, 2015 Journal Article, 2015

McCullagh L, Adams R, Barry M, Schmitz S, Walsh C, Evaluation Of 'Real-World' Ipilimumab Data In Ireland., Value Health, 18, (7), 2015, ppA441-A441- Poster, 2015

O'Brien C, Fogarty E, Walsh C, Dempsey O, Barry M, Kennedy MJ, McCullagh L, The cost of the inpatient management of febrile neutropenia in cancer patients - a micro-costing study in the Irish healthcare setting. , European Journal of Cancer Care, 2014 Journal Article, 2014 DOI

McCullagh LM, Tilson L, Adams R, Barry M, HTA Informed Price Negotiations: Cost Savings To The Health Payer in Ireland., 2014 Journal Article, 2014

Godman B, Finlayson AE, Cheema PK, Zebedin-Brandl E, Gutiérrez-Ibarluzea I, Jones J, Malmström RE, Asola E, Baumgärtel C, Bennie M, Bishop I, Bucsics A, Campbell S, Diogene E, Ferrario A, Fürst J, Garuoliene K, Gomes M, Harris K, Haycox A, Personalizing health care: feasibility and future implications., 2013 Journal Article, 2013

Schmitz S, McCullagh L, Adams R, Barry M, Walsh C, A retrospective analysis of drug reimbursement decisions in Ireland. A multi criteria decision analysis approach., Value Health, 2013, 16, (7), 2013, ppA465 - A465 Poster, 2013

Adams R, Gray E, McCullagh L, Schmitz S, Barry M, Walsh C, Budget impact and thresholds: how are real decisions made? Expected utility or Prospect Theory, Value Health, 16, (7), 2013, ppA490 - A490 Poster, 2013

Malmström RE, Godman BB, Diogene E, Baumgärtel C, Bennie M, Bishop I, Brzezinska A, Bucsics A, Campbell S, Ferrario A, Finlayson AE, Fürst J, Garuoliene K, Gomes M, Gutiérrez-Ibarluzea I, Haycox A, Hviding K, Herholz H, Hoffmann M, Jan S, Dabigatran - a case history demonstrating the need for comprehensive approaches to optimize the use of new drugs., 2013 Journal Article, 2013

McCullagh L, Barry M., Survival analysis used in company submissions to the National Centre for Pharmacoeconomics, Value Health, 16, (7), 2013, ppA398 - A398 Poster, 2013

McCullagh L, Walsh C, Barry M , Value-of-Information Analysis to Reduce Decision Uncertainty Associated with the Choice of Thromboprophylaxis after Total Hip Replacement in the Irish Healthcare Setting., PharmacoEconomics, 30, (10), 2012, p941 - 959 Journal Article, 2012 DOI

McCullagh L, Barry M, Prescribing trends for dabigatran etexilate in primary care., 2012 Journal Article, 2012

McCullagh L, Walsh C, Barry M, Integration of value of information into the decision making process in Ireland, Value Health, 15, (7), 2012, ppA317 - A317 Poster, 2012

McCullagh L, Usher C, Barry M, A review of the primary care prescribing of dabigatran etexilate and rivaroxaban in Ireland, Value Health, 14, (7), 2011, ppA390 - A390 Poster, 2011

McCullagh L, Walsh C, Barry M, Prioritizing further research using the expected value of perfect information: application to VTE prophylaxis post total hip replacement, Value Health, 13, (7), 2010, ppA359 - A359 Poster, 2010

McCullagh L, Tilson L, Walsh C, Barry M, A cost-effectiveness model comparing rivaroxaban and dabigatran etexilate with enoxaparin sodium as thromboprophylaxis after total hip and total knee replacement in the irish healthcare setting., 2009 Journal Article, 2009

McCullagh L, Tilson L, Walsh C, Barry M, Cost effectiveness of rivaroxaban and dabigatran etexilate for the prophylaxis of venous thromboembolism and associated long term compliactions post total hip replacement in Ireland, Value Health, 12, (7), 2009, ppA334 - A334 Poster, 2009

Hopkins S, Lambourne J, Farrell G, McCullagh L, Hennessy M, Clarke S, Mulcahy F, Bergin C., Role of individualization of hepatitis C virus (HCV) therapy duration in HIV/HCV-coinfected individuals., HIV Med. , 7, (4), 2006, p248-54. Journal Article, 2006 URL DOI

Clarke S, Delamere S, McCullough L, Hoskins S, Bergin C, Mulcahy F, Assessing limiting factors to the acceptance of antiretroviral therapy in a large cohort of injecting drug users, HIV Med, 4, (1), 2003, p33 - 37 Journal Article, 2003

Research Expertise

Description

Research interests to date include pharmacoeconomic evaluation, value of information analysis, multiple criteria decision analysis, survival analysis, cost of care studies and analysis of drug utilisation and expenditure in the real world setting. Laura is part of a collaborative team (including the University of Limerick, the National Cancer Registry and the NCPE)which has been awarded a HRB APA grant to examine how analysis of drug utilisation and real world outcomes databases can support pharmacoeconomic evaluations. Further, Laura is a Co-Applicant on a HRB RCQPS Award which is investigating how a GP practice-based Pharmacist Medicines Optimisation Programme might support prescribing in Irish primary care. Laura has published widely in peer reviewed journals and has presented her research at National, European and International Conferences. She has provided peer-review for a number of journals including: Value in Health, PharmacoEconomics, The European Journal of Health Economics, Thrombosis and Haemostasis, Journal of Hospital Medicine, Cost Effectiveness and Resource Allocation. She has also provided peer-review for the Innovational Research Incentive Scheme - Veni, Netherlands Organisation for Scientific Research. Laura is currently co-supervising 2 PhD students and 1 MSc student.

Recognition

Representations

Member of the National Centre for Pharmacoeconomics (NCPE)Technology Review Group 2008 - Date

Member of the National Cancer Control Programme (NCCP) Technology Review Group 2015 - Date

Awards and Honours

'Murdoch McKenzie' Prize for Highest Academic Grades in Pharmacy Undergrad Degree (1989-1991 inclusive), University of Sunderland, UK. 1991

'Mawson Proctor' Award for Highest Academic Grades in Pharmaceutical Chemistry & Pharmacognosy (Pharmacy), University of Sunderland, UK. 1990

'Boots' The Chemist Prize, for Highest Academic Grades in First Year of Pharmacy Undergrad Degree, University of Sunderland, UK. 1989

Memberships

Member of The Pharmaceutical Society of Ireland. 1998

Member of The Royal Pharmaceutical Society of Great Britain. 1992 – 1998


Last updated 21 September 2016 oneillm1@tcd.ie (Email).