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James O'Mahony
Research Fellow, Histopathology
Research Fellow, Public Health & Primary Care

Biography

Dr O'Mahony holds a BA in economics and philosophy from Trinity College Dublin, an MA in economics from University College Dublin and a PhD from Trinity College Dublin. He has always been interested in the way that economics influences public policy. Following his master's studies he worked at Goodbody Economic Consultants in Dublin, then a subsidiary of Goodbody Stockbrokers. His work at Goodbody's involved research for both public and private sector clients. While he found the consulting role interesting, he was keen to gain a sector specialty. Seeing health economics as a growing field with a large public policy element he decided to return to academics. James was awarded a Health Economics Fellowship by Ireland's Health Research Board (HRB). During his doctoral research James spent two years at the Department of Public Health at the Erasmus Medical Centre at Rotterdam, the Netherlands. During his time there James worked with the MISCAN microsimulation model of cancer prevention. His thesis concerned methodological questions in cost-effectiveness analysis (CEA), primarily relating to the fit of CEA models to policy questions. James spent the final year of his PhD studies working as an intern at the Health Information and Quality Authority (HIQA), where he contributed to both the organisation's Budget Impact Analysis (BIA) guidelines and to a CEA of breast screening for women of above average risk of disease. James now works at Trinity College Dublin as a postdoctoral researcher on the CERVIVA cervical cancer screening grant and is supported by a HRB Interdisciplinary Capacity Enhancement (ICE) award. He works in collaboration with clinical research specialists from Trinity's Department of Histopathology at the Coombe Hospital, Dublin.

Publications and Further Research Outputs

Peer-Reviewed Publications

O'Mahony, JF, van Rosmalen, J, Mushkudiani, NA, Goudsmit, F-W, Eijkemans, MJ, Heijnsdijk, EA, Steyerberg E & Habbema, JDF, The Influence of Disease Risk on the Optimal Time Interval between Screens for the Early Detection of Cancer A Mathematical Approach, Medical Decision Making, 2014 Journal Article, 2014 URL DOI Other

van Rosmalen, J, Toy, M, & O'Mahony, JF, A Mathematical Approach for Evaluating Markov Models in Continuous Time without Discrete-Event Simulation, Medical Decision Making, 33, (6), 2013, p767 - 779 Journal Article, 2013 URL DOI URL

O'Mahony, JF, & Paulden, M, NICE's Selective Application of Differential Discounting: Ambiguous, Inconsistent, and Unjustified, Value in Health: The Journal of The International Society for Pharmacoeconomics and Outcomes Research, 17, (5), 2013, p493 - 496 Journal Article, 2013 Other URL DOI

O'Mahony, JF, Cost-effectiveness of population-based screening for colorectal cancer, British Journal of Cancer, 108, (5), 2013, p1209 - 1210 Journal Article, 2013 Other DOI URL

O'Mahony JF, Newall AT, and van Rosmalen J, Dealing with Time in Health Economic Evaluation: Methodological Issues and Recommendations for Practice, PharmacoEconomics, 2015, pDOI 10.1007/s40273-015-0309-4 Journal Article, 2015 URL DOI Other

O'Mahony, JF., van Rosmalen, J, Zauber, AG and van Ballegooijen M, Multicohort Models in Cost-Effectiveness Analysis Why Aggregating Estimates over Multiple Cohorts Can Hide Useful Information, Medical Decision Making, 33, (3), 2013, p407 - 414 Journal Article, 2013 URL DOI Other

O'Mahony, JF, de Kok, IMCM, van Rosmalen, J, Habbema, JDF, Brouwer, WBF and van Ballegooijen, M, Practical implications of differential discounting in cost-effectiveness analyses with varying numbers of cohorts, Value in Health: The Journal of The International Society for Pharmacoeconomics and Outcomes Research, 14, (4), 2011, p438 - 442 Journal Article, 2011 URL DOI Other

Paulden, M and O'Mahony, JF, Why the National Institute for Health and Care Excellence's New Guidance on Discounting Creates Scope for Age Discrimination and other Inconsistencies, Bench, Bedside and Beyond: Medical Decision Making and Public Policy, Baltimore, MD, USA, October 19-23, 2013, 2013 Oral Presentation, 2013 URL

O'Mahony, JF, Postma, MJ, Boersma, C, Westra, TA, van Rosmalen, J and Jit, M, Correcting for Multiple Future Cohorts When Applying Differential Discounting of Costs and Health Effects, 14th Biennial SMDM European Meeting, Olso, Norway, June 10-12, 2012, 2012 Oral Presentation, 2012 URL

O'Mahony, JF and Paulden, M, NICE's Selective Application of Differential Discounting: Ambiguous, Inconsistent and Unjustified, ISPOR 18th Annual International Meeting; Patient-Centered Outcomes: Focusing on the Patient, New Orleans, LA, May 18-22, 2013, 2013 Poster, 2013 URL

O'Mahony, JF and O'Neill, C, The Health of Health Technology Assessment in Ireland: Five Points for Improvement, ISPOR 16th Annual European Congress, Dublin, Ireland, November 2-6, 2013, 2013 Poster, 2013 URL

O'Mahony, JF, van Rosmalen, J and van Ballegooijen, M, Multiple Cohort Modelling of Long-Duration Interventions: Questioning Time Horizons and Aggregation Across Cohorts, ISPOR 13th Annual European Congress, Prague, Czech Republic, November 6-9, 2010, 2010 Oral Presentation, 2010 URL

O'Mahony, JF, Naber, S and de Kok, IMCM, A Critical Appraisal of Cost-Effectiveness Analyses of Human Papillomavirus Testing in Cervical Screening: Making Appropriate Comparisons and Usefully Interpreting Results, ISPOR 16th Annual European Congress, Dublin, Ireland, November 2-6, 2013, 2013 Poster, 2013 URL

Paulden, M and O'Mahony, JF, The 2013 Revision To NICE's Discounting Guidelines: Differential Discounting has Gone but Unjustified Selective Application Remains, ISPOR 16th Annual European Congress, Dublin, Ireland, November 2-6, 2013, 2013 Poster, 2013 URL

O'Mahony, JF, Critical Appraisal of Cost-Effectiveness Analyses of Human Papillomavirus Testing in Cervical Screening: Appropriate Comparisons and the Useful Interpretations of Results, 35th Annual North American Meeting of the Society for Medical Decision Making, Baltimore, MD, USA, October 19-23, 2013, 2013 Poster, 2013 URL

Ekwunife O, Gerber-Grote A, Mosch C, O'Mahony J, and Lhachimi S, Assessing cost-effectiveness of HPV vaccines with decision analytic models: what are the distinct challenges of low- and middle-income countries? A protocol for a systematic review, Systematic Reviews, 4, (68), 2015, p2 - 9 Journal Article, 2015 Other DOI URL

Paulden, M, O'Mahony, JF, Culyer, AJ, & McCabe, C, Objectivity and Equity: Clarity Required. A Response to Hill and Olson, PharmacoEconomics, 32, (12), 2014, p1249 - 1250 Journal Article, 2014 DOI URL Other

Paulden, M, O'Mahony, JF, Culyer, AJ, & McCabe, C, Some Inconsistencies in NICE's Consideration of Social Values, PharmacoEconomics, 32, (11), 2014, p1043 - 1053 Journal Article, 2014 Other URL DOI

Research Expertise

Description

Dr O'Mahony's primary research interests are in methods of cost-effectiveness analysis (CEA), particularly modelling methods. Most broadly, James is interested in the way the policy questions faced by decision makers are interpreted by analysts when constructing models and communicating results back to decision makers. He is interested in how well the model estimates provided to decision makers fit the policy questions at hand. One of the areas of interest for James where models may not fit with policy questions is where there are multiple heterogeneous cohorts that are potential recipients of a given intervention. Differential discounting of cost and health effects leads to examples of models with heterogeneous cohorts. James is also interested in the representation of uncertainty to decision makers, particularly probabilistic sensitivity analysis and cost-effectiveness acceptability curves.

Recognition

Memberships

Society of Medical Decision Making

International Society of Pharmacoeconomics and Outcomes Research


Last updated 21 September 2016 Paul Smyth (Email).