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The Irish Cervical Screening Research Consortium

The Irish Cervical Screening Research Consortium "Cerviva" was established in 2005 to perform high quality research into cervical screening options, offer support to the Irish Cervical Screening Programme and improve the quality of cervical screening in Ireland. The consortium is comprised of scientists, clinicians, epidemiologists, health economists and has significant hospital, academic, biotechnology and national agency support.

Cerviva seeks to introduce major innovations in the cervical screening process through the introduction of automation, ancillary viral testing for use in management triage and the development of objective biomarkers and biosensors for use as prognostic indicators of disease outcome.

There are eight individual component projects underway within CERVIVA. These include:

  • Introduction of automated cytology: a cost base analysis of automated screening compared with manual screening approaches
  • Introduction of a virtual slide based external quality assessment (EQA) system in Irish cytopathology.
  • Population based survey of the attitudes of women to cervical screening and HPV oncogenic testing.
  • Establishment of a cervical screening and Human Papillomavirus Virus out reach education programme.
  • HPV DNA and mRNA testing in the Irish cervical screening population.
  • Screening HIV positive women for HPV RNA transforming genes as a role in the prevention of cervical cancer in this population.
  • Examination of the effect of introducing a HPV vaccine in the Irish population: a longitudinal analysis of risk.
  • Development of cervical biochips/ biosensors

A publicly accessible website has been established. This website is regularly update with news items relating to the projects with a list of publications and presentations to date and contains links to national and international cancer agencies and research groups.


Academic Institutions

  • National Centre for Sensor Research, Dublin City University (DCU)
  • Kevin Street College of Technology (DIT)
  • Dept of Obstetrics and Gynaecology Royal College of Surgeons in Ireland (RCSI)
  • Dept of Histopathology, Trinity College Dublin (TCD)
  • Dept of Pathology, University College Cork (UCC)
  • Dept of Pathology, University College Galway (UCG)
  • Dept of Pathology, University College Dublin (UCD)
  • Free University of Amsterdam
  • University of Oslo

Hospital Affiliates

  • Dept of Pathology, Coombe Women's Hospital, Dublin (Coombe)
  • Dept of Cytopathology, St. James's Hospital Dublin (St James)
  • Dept of Obstetrics and Gynaecology, St. James's Hospital Dublin (St James)
  • Cancer Molecular Diagnostics, St. James's Hospital, Dublin (St James)
  • Dept of Cytopathology, St.Luke's Hospital Dublin (St Luke's)
  • Dept of Cytopathology, University Hospital Galway (UHG)
  • Dept of Cytopathology, Beaumont Hospital, Dublin (Beaumont)
  • Dept of Pathology, The National Maternity Hospital, Dublin (NMH)
  • Dept of Pathology, The Rotunda Hospital, Dublin (Rotunda)
  • Dept of Cytopathology, Cork University Hospital, Cork (CUH)

Commercial Organisations

  • Affymetrix, UK
  • Celera Diagnostics / Applied Biosystems, UK
  • Cytyc, USA
  • Tripath, USA
  • Dakocytomation, Denmark
  • Digene Corporation, USA
  • Norchip AS, Norway
  • Roche Diagnostics, UK
  • Biotrin, Ireland
  • SlidePath, Dublin (a DCU campus company)

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Last updated 21 September 2016 Paul Smyth (Email).