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Dr. Brendan Grufferty
Lecturer/Consultant in Restorative Denti, Dental Science

Biography

- D.O.B. 10/10/1966 - Nationality: Irish

-Undergraduate: - Dec '90: BA B.Dent.Sc. - POST-GRADUATION EMPLOYMENT: - Jan '91 - Apr '95 General Dental Practice in London, UK. - Graduate training: - Aug '95 - Jun '99 Graduate training in Prosthodontics (Uni. at Buffalo,NY).

M.S.(Biomaterials) Uni. at Buffalo, NY.

Residency in Maxillofacial Prosthetics, Buffalo - EMPLOYMENT FOLLOWING GRADUATE TRAINING: - Nov '99 - Feb '05 Part-time private dental practice in London, UK.

Part-time NHS based hospital practice in UK. - Academic appointment: - Mar '05 - Dec '11 Lecturer in Restorative Dentistry, DDUH.

Research in Biomedical and Bioengineering fields (PhD). - Jan '12 - Jun '17 Lecturer/Locum Consultant in Restorative Dentistry, DDUH. Jul '17 - present Assistant Professor / Consultant in Restorative Dentistry, DDUH.

Publications and Further Research Outputs

Peer-Reviewed Publications

Alotaibi M, Moran G, Grufferty B, Renvert S, Polyzois I. , The effect of a decontamination protocol on contaminated titanium dental implant surfaces with different surface topography in edentulous patients. , Acta Odontologica Scandanavia, 77, (1), 2019, p66 - 75 Journal Article, 2019 URL

Esposito M, Grufferty B, Papavasiliou G Dominiak M, Trullenque-Eriksson, Heinemann F. , Immediate loading of occluding definitive partial fixed prostheses vs non-occluding provisional restorations - 3 year post-loading result of a pragmatic multicentre randomised clinical trial. , Eur J Oral Implantol, 11, (3), 2018, p309 - 320 Journal Article, 2018

Heinemann F, Grufferty B, Papavasiliou G, Dominiak M, Garcia JJ, Trullenque-Erikson A, Esposito M., Immediate occluding definitive partial fixed restorations - 4 month post-loading results from a pragmatic multicenter randomized clinical trial., European Journal of Oral implantology, 9, (1), 2016, p47 - 56 Journal Article, 2016

Moorthy A, Hogg CH, Dowling AH, Grufferty BF, Benetti AR, Fleming GJP., Cuspal deflection and microleakage in premolar teeth restored with bulk-fill flowable resin-based composite base materials., Journal of Dentistry, 40, (6), 2012, p500 - 505 Journal Article, 2012

Research Expertise

Description

-Clinical restorative dentistry, dental materials and biomaterials. -Dental implant surfaces: Physical and chemical manipulation of metallic implant surfaces to enhance protein and bone cell interaction with the aim of enhancing speed and extent of bone formation at the bone-implant interface. -Bone and cell biology, and biochemistry: as it relates to healing following surgical placement of endosseous implants.

Projects

  • Title
    • A Prospective, Single Blind, Crossover Clinical Trial to Assess the Outcomes of Computer-Engineered Complete Dentures using Impressions and Intra-Oral Scans of the Edentulous Arches
  • Summary
    • Clinical and patient centred assessments of maxillary and mandibular complete dentures, fabricated using a commercially available CAD/CAM system. The prostheses were designed and fabricated using impressions and intraoral scans of the edentulous arches.
  • Funding Agency
    • DDUH
  • Date From
    • Jun '20
  • Date To
    • Sept '22
  • Title
    • An in-vitro assessment of the retrievability of fractured dental implant abutment screws
  • Summary
    • A clinical simulation to compare the relative effectiveness of a commercially available screw fragment retrieval kit and standard dental instruments in retrieving fractured abutment screw fragments from dental implants.
  • Funding Agency
    • Dublin Dental University Hospital
  • Date From
    • Apr '19
  • Date To
    • Dec '20
  • Title
    • Definitive immediate restorations versus non-occluding provisional restorations in partially edentulous patients. A pragmatic multicenter randomized clinical trial.
  • Summary
    • Assessing the clinical and radiographic outcomes of dental implants and restorations which were immediately loaded with definitive restorations or provisionally restored for four months prior definitive restoration.
  • Funding Agency
    • Biomet 3i
  • Date From
    • Jan '14
  • Date To
    • Apr '24
  • Title
    • Occlusal Stability of Bilateral Free-end Saddle Removable Partial Dentures
  • Summary
    • Longitudinal assessment of the pattern of occlusal contacts in participants wearing bilateral free-end saddle removable partial dentures using a digital occlusal analysis system.
  • Funding Agency
    • Dublin Dental University Hospital
  • Date From
    • Sept '13
  • Date To
    • Dec '15
  • Title
    • Use of a three-dimensional scaffold to study bone cell growth and differentiation on commercially pure titanium
  • Summary
    • Mesenchymal stem cell behaviour and differentiation in 3D scaffold on titanium substrate.
  • Funding Agency
    • Dublin Dental University Hospital
  • Date From
    • Apr '05
  • Date To
    • Nov '11
  • Title
    • Load-displacement evalutaion of fiber-reinforced resin composite fixed partial denture materials.
  • Summary
    • Adhesive bridge framework models designed with commercially available fibre-reinforced resin materials and bonded to bovine enamel were subjected to simulated occlusal loading. Stiffness values were compared and SEM images obtained to assess behaviour of the specimens under loading and determine the suitability of the materials for clinical use. Results revealed that these materials are not suitable for clinical use intended because of widespread evidence of microscopic failure, which would presumably lead to eventual macroscopic or clinical failure.
  • Funding Agency
    • Dept of Restorative Dentistry, University at Buffalo, NY
  • Date From
    • Aug '95
  • Date To
    • Apr '99
  • Title
    • Clinical and microscopic evaluation of periabutment soft tissue surrounding intraoral percutaneous commercially pure titanium implants, a pilot study.
  • Summary
    • Intraoral skin grafts used to repair defects following ablative surgery for oral cancer which were used in association with dental implant abutments. The response of the peri-implant abutment tissue appeared as hyperplastic and inflamed. Biopsies of the intraoral skin grafts were prepared for histopathological analysis. X-ray diffraction analysis also completed to assess the presence of titanium particles in the tissue.
  • Funding Agency
    • Roswell Park Cancer Institute, Buffalo, NY
  • Date From
    • Jul. '98
  • Date To
    • Jun. '99

Keywords

ADHESION; Biology; Biomaterials; Biomedical Engineering; Biomedical sciences; CANCER PATIENTS; Caries; Dentistry; digital technology; Oral Health

Recognition

Representations

Member of examination appeals subcommittee for Dental Council Statutory Examinations April 2018

Memberships

International Society of Maxillofacial Rehabilitation 2023 – present

British Society of Prosthodontics 2023 – present

International Association of Dental Research 2023 – present

American Dental Society of London 1999 – 2005

British Dental Association 1999 – 2005