Skip to main content

Trinity College Dublin, The University of Dublin

Menu Search



Brendan Grufferty
Lecturer/Consultant in Restorative Denti, Dental Science

Biography

- D.O.B. 10/10/1966 - Nationality: Irish -Undergraduate: - Dec '90: Graduated from TCD with BA B.Dent.Sc. - Post-graduation employment: - Jan '91 - Apr '95 General Dental Practice in London, UK. - Graduate training: - Aug '95 - Jun '99 Graduate training in Prosthodontics in Buffalo,NY. M.S.(Biomaterials) Uni. of Buffalo, NY. Residency in Maxillofacial Prosthetics, Buffalo - Employment following graduate training: - Nov '99 - Feb '05 Part-time private dental practice in London, UK. Part-time NHS based hospital practice in UK. - Academic appointment: - Mar '05 - Lecturer in Restorative Dentistry, Dublin Dental Hospital. Research in Biomedical and Bioengineering fields.

Research Expertise

Description

-Clinical restorative dentistry, dental and biomaterials. -Dental implant surfaces: Physical and chemical manipulation of metallic implant surfaces to enhance protein and bone cell interaction with the aim of enhancing speed and extent of bone formation at the bone-implant interface. -Bone and cell biology, and biochemistry: as it relates to healing following surgical placement of endosseous implants.

Projects

  • Title
    • Load-displacement evalutaion of fiber-reinforced resin composite fixed partial dentuire materials.
  • Summary
    • Specimens of commercially available, fiber-reinforced resin composite materials were fabricated (dimensions were that of the connector for an anterior adhesive bridge, replacing a central incisor). Specimens were bonded to bovine enamel and loaded to the average interincisal force. Average stiffness values were calculated, and SEM images of loaded specimens were obtained. Results demonstrated that glass fiber-reinforced specimens were stiffer than polyethylene fibre-reinforced specimens. All specimens demonstrated microscopic evidence of fibre delamination and matrix/fibre fracture. Brittle glass-fibre specimens fractured more readily and polyethylene-fibre specimens stretched. Results revealed that these materials are not suitable for clinical use intended because of widespread evidence of microscopic failure, which would presumably lead to eventual macroscopic or clinical failure.
  • Funding Agency
    • Dept of Restorative Dentistry, University at Buffalo, NY
  • Date From
    • Aug '95
  • Date To
    • Apr '99
  • Title
    • Clinical and microscopic evaluation of periabutment soft tissue surrounding intraoral percutaneous commercially pure titanium implants, a pilot study.
  • Summary
    • Skin grafts are commonly used intraorally to repair defects caused following ablative surgery for oral cancer. Dental implants abutments that penetrate these skin grafts demonstrated a clinical picture of chronic inflammation and hyperplasia. Even with meticulous oral hygiene practices, the clinical appearance of these tissues do not resolve completely. Soft tissue biopsies were taken and histomorphometric analysis was carried out. Specimens were also prepared for X-ray diffraction analysis. Histomorphometrically the picture was one of non-specific chronic inflammation, with enlargement of rete pegs of the cutaneous eptihelium. X-ray diffraction analysis did not reveal any significant deposits of foreign matter (eg Titanium) in the soft tissue. Reccomendations were that periabutment skin should be as thin as possible and excellent oral hygiene should be maintained.
  • Funding Agency
    • Roswell Park Cancer Institute, Buffalo, NY
  • Date From
    • Jul. '98
  • Date To
    • Jun. '99

Keywords

Bioengineering and radiologic imaging; Biology; Biomaterials; Biomedical Engineering; Biomedical sciences; Caries; Dentistry; Oral Health