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Garry Fleming
Associate Professor, Dental Science

Publications and Further Research Outputs

Peer-Reviewed Publications

Cao X, Fleming GJP, Addison O, The impact of resin-coating on sub-critical crack extension in a porcelain laminate veneer material, Dental Materials, 33, (5), 2017, p498 - 504 Journal Article, 2017

McHugh LEJ, Politi I, Al-Fodeh RS, Fleming GJP, Implications of resin-based composite (RBC) restoration on cuspal deflection and microleakage score in molar teeth: Placement protocol and restorative material, Dental Materials, 33, (e), 2017, p329 - 335 Journal Article, 2017

Duncan HF, Smith AJ, Fleming GJP, Reid C, Smith G, Cooper PR, Release of bio-active dentine extracellular matrix components by histone deacetylase inhibitors (HDACi) , International Endoodntic Journal, 50, (1), 2017, p24 - 38 Journal Article, 2017 DOI

Altaie A, Bubb NL, Franklin P, Dowling AH, Fleming GJP, Wood DJ, An approach to understanding tribological behaviour of dental composites through volumetric wear loss and wear mechanism determination; beyond material ranking., Journal of Dentistry, 59, (2), 2017, p41 - 47 Journal Article, 2017

Fleming GJP, Cao X, Romanyk DL, Addison O, Favorable residual stress induction by resin-cementation on dental porcelain, Dental Materials, 33, (11), 2017, p1258 - 1265 Journal Article, 2017

Benetti AR, Larsen L, Dowling AH, Fleming GJP, Assessment of wear facets produced by the ACTA wear machine, Journal of Dentistry, 45, (2), 2016, p19 - 25 Journal Article, 2016 DOI URL

Fleming GJP, Reilly E, Dowling AH, Addison O, Data acquisition variability using profilometry to produce accurate mean total volumetric wear and mean maximum wear depth measurements for the OHSU oral wear simulator, Dental Materials, 32, (8), 2016, pe176 - e184 Journal Article, 2016 DOI URL

Duncan HF, Smith AJ, Fleming GJP, Partridge NC, Shimizu E, Moran GP, Cooper PR, The Histone-Deacetylase-Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase-13 Activity., Journal of Cellular Physiology, 231, (4), 2016, p798 - 816 Journal Article, 2016 DOI

Costa AK, Kelly RD, Fleming GJP, Borges AL, Addison O, Laminated ceramics with elastic interfaces: a mechanical advantage?, Journal of Dentistry, 43, (3), 2015, p335 - 341 Journal Article, 2015

Duncan HF, Smith AJ, Fleming GJP , Moran GP, Cooper PR., Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points , Genomic Data, 5, 2015, p391 - 393 Journal Article, 2015 TARA - Full Text

Baig MS, Dowling AH, Cao X, Fleming GJP, A discriminatory mechanical testing performance indicator protocol for hand-mixed glass-ionomer restoratives, Dental Materials, 31, (3), 2015, p273 - 283 Journal Article, 2015 DOI URL

Baig MS, Fleming GJP, Conventional glass-ionomer materials: A review of the developments in glass powder, polyacid liquid and the strategies of reinforcement, Journal of Dentistry, 43, (8), 2015, p897 - 912 Review Article, 2015

Duncan HF, Smith AJ, Fleming GJP, Partridge NC, Shimizu E, Moran GP, Cooper PR, The histone-deacetylase-inhibitor suberoylanilide hydroxamic acid promotes dental pulp repair mechanisms through modulation of matrix metalloproteinase-13 activity, Journal of Cellular Physiology, 231, (4), 2015, p798-816 Journal Article, 2015 DOI

Ilie N, Fleming GJP, In vitro comparison of polymerisation kinetics and the micro-mechanical properties of low and high viscosity giomers and RBC materials, Journal of Dentistry, 43, (7), 2015, p814 - 822 Journal Article, 2015

Baig MS, Dowling AH, Cao X, Fleming GJP, A discriminatory performance indicator for hand-mixed glass-ionomer restoratives, Dental Materials, 31, (3), 2015, p273 - 283 Journal Article, 2015

Baig MS, Lloyd CH, Fleming GJP, Fracture toughness testing: A discriminatory mechanical testing performance indicator for glass-ionomer restoratives?, Dental Materials, 31, (8), 2015, p877 - 886 Journal Article, 2015

Tomaszewska IM, Kearns JO, Ilie N Fleming GJP, Bulk fill restoratives: To cap or not to cap - That is the question?, Journal of Dentistry, 43, (3), 2015, p309 - 315 Journal Article, 2015

Rehola J, Lassila LVJ, Nganga S, Yla-Soininmaki A, Fleming GJP, Grenman R, Aho AJ, Vallittu PK, Effect of heat treatment of wood on the morphology, surface roughness and penetration of simulated and human blood., Bio-Medical Materials and Engineering, 24, (3), 2014, p1595 - 1607 Journal Article, 2014

Hooi P, Addison O, Fleming GJP, Strength determination of brittle materials as curved momotlthic structures, Journal of Dental Research, 93, (4), 2014, p412 - 416 Journal Article, 2014 DOI

Costa AK, Borges AL, Fleming GJP, Addison O, The strength of sintered and adhesively bonded zirconia/veneer-ceramic bilayers, Journal of Dentistry, 42, (10), 2014, p1269 - 1276 Journal Article, 2014

Kearns JO, Barry JB, Fleming GJP, Cuspal deflection and cervical microleakage scores to determine the adhesive potential of universal bonding systems., Journal of Dentistry, 42, (8), 2014, p970 - 976 Journal Article, 2014

Burns A, Dowling AH, Garvey TM, Fleming GJP, The reliability of Little's Irregularity Index for the upper dental arch using three dimensional (3D) digital models, Journal of Dentistry, 42, (10), 2014, p1320 - 1326 Journal Article, 2014

Fleming GJP, Advances in Dental Materials, Primary Dental Journal, 3, (2), 2014, p54 - 61 Journal Article, 2014

Palin WM, Hadis MA, Leprince JG, Leloup G, Boland L, Fleming GJP, Krastl G, Watts DC, Reduced polymerization stress of MAPO-containing resin composites with increased curing speed, degree of conversion and mechanical properties., Dental Materials, 30, (5), 2014, p507 - 516 Journal Article, 2014 DOI

Sultan A, Moorthy A, Fleming GJP, The adhesive potential of dentine bonding systems using cuspal deflection measurements combined with cervical microleakage scores, Dental Materials, 30, (10), 2014, p1154 - 1160 Journal Article, 2014

Kelly RD, Fleming GJP, Hooi P, Palin WM, Addison O, Biaxial flexure strength determination of endodontically accessed ceramic restorations, Dental Materials, 30, (7), 2014, p902 - 909 Journal Article, 2014

Hooi P, Addison O, Fleming GJP, Atmospheric moisture and cementation seating load effects on resin-strengthening of a dental porcelain analogue, Journal of Dentistry, 41, (12), 2013, p1208 - 1213 Journal Article, 2013 DOI

McGinley E, Moran GP, Dowling AH, Fleming GJP, S Mutans exacerbates base-metal dental casting alloy toxicity. , Journal of Dental Research, 92, (1), 2013, p92 - 97 Journal Article, 2013 DOI

Finlay N, Hahnel S, Dowling AH, Fleming GJP, The in-vitro wear behaviour of experimental resin-based composites derived from a commercial formulation , Dental Materials, 29, (4), 2013, p365 - 374 Journal Article, 2013 DOI

Hooi P, Addison O, Fleming GJP , Testing rate and cementation seating load effects on resin-strengthening of a dental porcelain analogue, Journal of Dentistry, 41, (6), 2013, p514 - 520 Journal Article, 2013 DOI

Hooi P, Addison O, Fleming GJP, Can a soda-lime glass be used to demonstrate how patterns of strength dependence are influenced by pre-cementation and resin-cementation variables?, Journal of Dentistry, 41, (1), 2013, p24 - 30 Journal Article, 2013 DOI

Finan L, Palin WM, Moskwa N, McGinley EL, Fleming GJP, The influence of irradiation potential on the degree of conversion and mechanical properties of two bulk-fill flowable RBC base materials., Dental Materials, 29, (8), 2013, p906 - 912 Journal Article, 2013 DOI

Dowling AH, Burns A, McCauley D, Garvey T, Fleming GJP, Can the intra-examiner variability of Little's Irregularity Index be improved using 3D digital models of study casts?, Journal of Dentistry, 41, (12), 2013, p1271 - 1280 Journal Article, 2013 DOI

Baig MS, Dowling AH, Fleming GJP, Hertzian indentation testing of glass-ionomer restorative: A reliable and clinically relevant testing approach, Journal of Dentistry, 41, (11), 2013, p968 - 973 Journal Article, 2013 DOI

El-Helali R, Dowling AH, McGinley EL, Duncan HF, Fleming GJP, Influence of resin-based composite restoration technique and endodontic access on cuspal deflection and cervical microleakage scores, Journal of Dentistry, 41, (3), 2013, p216 - 222 Journal Article, 2013 DOI

McGinley E, Moran GP, Fleming GJP, Biocompatibility effects of indirect exposure of base-metal dental casting alloys to a human-derived three-dimensional oral mucosal model, Journal of Dentistry, 41, (11), 2013, p1091 - 1100 Journal Article, 2013 DOI

Duncan HF, Smith AJ, Fleming GJP, Cooper PR, HDACi epigenetically promote reparative events in primary dental pulp cells, Experimental Cell Research, 319, (10), 2013, p1534 - 1543 Journal Article, 2013 DOI

Fleming GJP, Dowling AH, Addison O, The crushing truth about glass ionomer restoratives: exposing the standard of the standard, Journal of Dentistry, 40, (3), 2012, p181 - 188 Journal Article, 2012 TARA - Full Text

Dowling AH, Fleming GJP, McGinley EL, Addison O, Improving the standard of the standard for glass ionomers: an alternative to the compressive fracture strength test for consideration?, Journal of Dentistry, 40, (3), 2012, p189 - 201 Journal Article, 2012 TARA - Full Text

Hahnel S, Dowling AH, El-Safty S, Fleming GJP, The influence of monomeric resin and filler characteristics on the performance of experimental resin-based composites (RBCs) derived from a commercial formulation., Dental Materials, 28, (4), 2012, p416 - 423 Journal Article, 2012

Fleming GJP, Hooi P, Addison O, The influence of resin flexural modulus on the magnitude of ceramic strengthening, Dental Materials, 28, (7), 2012, p769 - 776 Journal Article, 2012

Addison O, Cao X, Sunnar P, Fleming GJP, Machining variability impacts on the strength of a chairside CAD-CAM ceramic, Dental Materials, 28, (8), 2012, p880 - 887 Journal Article, 2012

Duncan HF, Smith AJ, Fleming GJP, Cooper PR, Histone deacetylase inhibitors induced differentiation and accelerated mineralization of pulp-derived cells, Journal of Endodontics, 38, (3), 2012, p339 - 345 Journal Article, 2012

McGinley, E.L., Moran, G.P., Fleming, G.J.P., Base-metal dental casting alloy biocompatibility assessment using a human-derived 3D oral mucosal model, Acta Biomaterialia, 8, (1), 2012, p432 - 438 Journal Article, 2012 TARA - Full Text

Colombo JS, Carley A, Fleming GJP, Crean St.J, Sloan AJ, Waddington RJ, , Osteogenic potential of bone marrow stromal cells on smooth, roughened and tricalcium phosphate-modified Titanium alloy surfaces, The International Journal of Oral & Maxillofacial Implants , 27, (5), 2012, p1029 - 1042 Journal Article, 2012

Moorthy A, Hogg CH, Dowling AH, Grufferty BF, Benetti AR, Fleming GJP, Cuspal deflection and microleakage in premolar teeth restored with bulk-fill flowable resin-based composite base materials, Journal of Dentistry, 40, (6), 2012, p500 - 505 Journal Article, 2012 TARA - Full Text

McCauley D, Garvey T, Dowling AH, Fleming GJP , Using Little's Irregularity Index in orthodontics: Outdated and inaccurate?, Journal of Dentistry, 40, (12), 2012, p1127 - 1133 Journal Article, 2012 DOI

Dowling AH, Fleming GJP, The influence of poly(acrylic) acid number average molecular weight and concentration in solution on the compressive fracture strength and modulus of a glass-ionomer restorative, Dental Materials, 27, (6), 2011, p535 - 543 Journal Article, 2011

Duncan HF, Smith AJ, Fleming GJP, Cooper PR, HDACi: Cellular Effects, Opportunities for Restorative Dentistry, Journal of Dental Research, 90, (12), 2011, p1377 - 1388 Journal Article, 2011

McGinley E, Moran GP, Coleman DC, Fleming GJP, Effects of surface finishing condition on the biocompatibility of a nickel-chromium dental casting alloy, Dental Materials, 27, (7), 2011, p637 - 650 Journal Article, 2011

McGinley EL, Fleming GJP, Moran GP, Development of a discriminatory biocompatibility testing model for non-precious dental casting alloys, Dental Materials, 27, (12), 2011, p1295 - 1306 Journal Article, 2011

Isgró G, Addison O, Fleming GJP, Transient and residual stresses in a pressable glass-ceramic before and after resin-cement coating determined using profilometry, Journal of Dentistry, 39, (5), 2011, p368 - 375 Journal Article, 2011

Isgró G, Addison O, Fleming GJP, The deformation and strength of a dental ceramic following resin-cement coating, Journal of Dentistry, 39, (2), 2011, p122 - 127 Journal Article, 2011 TARA - Full Text

Dowling AH, Fleming GJP, Can poly(acrylic) acid molecular weight mixtures improve the compressive fracture strength and elastic modulus of a glass-ionomer restorative? , Dental Materials, 27, (11), 2011, p1170 - 1179 Journal Article, 2011

Isgró G, Addison O, Fleming GJP, Transient and residual stresses induced during the sintering of two dentin ceramics., Dental Materials, 27, (4), 2011, p379 - 285 Journal Article, 2011 TARA - Full Text

Addison O, Sodhi A, Fleming GJP , Seating load parameters impact on dental ceramic reinforcement conferred by cementation with resin-cements., Dental Materials , 26, (9), 2010, p915 - 921 Journal Article, 2010

McMahon C, Kinsella D, Fleming GJP, Extrusion-mixing compared with hand-mixing of polyether impression materials?, The European Journal of Prosthodontic and Restorative Dentistry, 18, (4), 2010, p150 - 154 Journal Article, 2010

Bhamra GS, Fleming GJP, Darvell BW , Influence of LED irradiance on flexural properties and Vickers Hardness of resin-based composite materials, Dental Materials , 26, (2), 2010, p145 - 152 Journal Article, 2010

Isgró G, Addison O, Fleming GJP, Stress induced deformation of a dental ceramic following adhesive cementation, Journal of Dental Research , 89, (1), 2010, p87 - 90 Journal Article, 2010

Fleming GJP, Addison O , Adhesive cementation and the strengthening of all-ceramic dental restorations. , Journal of Adhesion Science and Technology, 23, (7-8), 2009, p945 - 959 Journal Article, 2009

Bhamra GS, Fleming GJP , Influence of halogen light irradiance on short- and long-term wear resistance of resin-based composite materials, Dental Materials, 25, (2), 2009, p214 - 220 Journal Article, 2009

Dowling AH, Fleming GJP , Are encapsulated anterior glass-ionomer restoratives better than their hand-mixed equivalents?, Journal of Dentistry, 37, (2), 2009, p133 - 140 Journal Article, 2009

Curtis AR, Palin WM, Fleming GJP, Shortall ACC, Marquis PM, The mechanical properties of nanofilled resin-based composites: Characterising discrete filler particles and agglomerates using a micromanipulation technique, Dental Materials , 25, (2), 2009, p180 - 187 Journal Article, 2009

Curtis AR, Palin WM, Fleming GJP, Shortall ACC, Marquis PM, The mechanical properties of nanofilled resin-based composites: The impact of dry and wet cyclic pre-loading n bi-axial flexure strength, Dental Materials, 25, (2), 2009, p188 - 197 Journal Article, 2009

Addison O, Marquis PM, Fleming GJP, Quantifying the strength of a resin-coated ceramic, Journal of Dental Research, 87, (6), 2008, p542 - 547 Journal Article, 2008

Bhamra GS, Fleming GJP , Effects of halogen light irradiation variables (tip diameter, irradiance, irradiation protocol) on flexural strength properties of resin-based composites. , Journal of Dentistry , 36, (8), 2008, p643 - 650 Journal Article, 2008

Fleming GJP, Awan M, Cooper PR, Sloan AJ, The potential of a resin-based composite to be cured to a 4 mm depth, Dental Materials, 24, (4), 2008, p522 - 529 Journal Article, 2008

Dowling AH, Fleming GJP, Is encapsulation of posterior glass-ionomer restoratives the solution to clinically induced variability introduced on mixing?, Dental Materials, 24, (7), 2008, p957 - 966 Journal Article, 2008

Burke FJT, Hussain A, Nolan L, Fleming GJP, Methods used in dentine bonding tests: An analysis of 102 investigations on bond strength, European Journal of Prosthodontics and Restorative Dentistry, 16, (4), 2008, p158 - 165 Journal Article, 2008

Addison O, Fleming GJP , Application of analytical stress solutions to bi-axially loaded dental ceramic-dental cement bilayers., Dental Materials, 24, (9), 2008, p1336 - 1342 Journal Article, 2008

Addison O, Marquis PM, Fleming GJP, Adhesive luting of all-ceramic restorations -the impact of cementation variables and short term water storage on the strength of a feldspathic dental ceramic, Journal of Adhesive Dentistry , 10, (4), 2008, p285 - 293 Journal Article, 2008

Addison O, Marquis PM, Fleming GJP , The impact of hydrofluoric acid surface treatments on the performance of a porcelain laminate restorative material., Dental Materials, 23, (4), 2007, p461 - 468 Journal Article, 2007

Addison O, Marquis PM, Fleming GJP, The impact of modifying alumina air abrasion parameters on the performance of a porcelain laminate restorative material, Dental Materials, 23, (11), 2007, p1332 - 1341 Journal Article, 2007

Addison O, Marquis PM, Fleming GJP, Resin strengthening of dental ceramics -the impact of surface texture and silane, Journal of Dentistry, 35, (5), 2007, p416 - 424 Journal Article, 2007

Wylie CM, Davenport AJ, Fleming GJP, Shelton RM, Corrosion of Ni-based dental casting alloys, Dental Materials , 23, (6), 2007, p714 - 723 Journal Article, 2007

Dowling AH, Fleming GJP, The impact of montmorillonite clay addition on the in-vitro wear resistance of a glass-ionomer restorative, Journal of Dentistry , 35, (4), 2007, p309 - 317 Journal Article, 2007

Fleming GJP, Khan S, Afzal O, Palin WM, Burke FJT, The influence of a light emitting diode light curing unit on cuspal movement and microleakage in premolar teeth restored with resin-based filling. , Journal of Dentistry , 35, (2), 2007, p97 - 103 Journal Article, 2007

Fleming GJP, Cara RR, Palin WM, Burke FJT, Cuspal movement and microleakage in premolar teeth restored with resin-based filling materials cured using a 'soft-start' polymerisation protocol., Dental Materials, 23, (5), 2007, p637 - 643 Journal Article, 2007

Addison O, Marquis PM, Fleming GJP, Resin elasticity and the strengthening of all-ceramic restorations, Journal of Dental Research, 86, (6), 2007, p519 - 523 Journal Article, 2007

Cara RR, Fleming GJP, Palin WM, Walmsley AD, Burke FJT, Cuspal deflection and microleakage in premolar teeth restored with resin-based composites with and without an intermediary flowable layer, Journal of Dentistry, 35, (6), 2007, p482 - 489 Journal Article, 2007

Burke FJT, Fleming GJP, Abbas G, Richter B, Effectiveness of a self-adhesive resin luting system on fracture resistance of teeth restored with dentin-bonded crowns. , The European Journal of Prosthodontic and Restorative Dentistry , 14, (4), 2006, p185 - 189 Journal Article, 2006

Fleming GJP, Maguire FR, Bhamra G, Burke FM, Marquis PM., The influence of dental cements on controlled porcelain surface preparations. , Journal of Dental Research, 85, (3), 2006, p272 - 276 Journal Article, 2006

Shaini FJ, Wahab FK, Shortall ACC, Fleming GJP, Marquis PM., Marginal adaptation and micro-porosity of class II restorations of a high copper amalgam and a palladium-free gallium-based alloy. , Journal of Oral Rehabilitation , 33, (12), 2006, p924 - 933 Journal Article, 2006

Dental materials science in, editor(s)Mossey PA, Holsgrove GJ, Stirrups DR, Davenport ES , Essential skills for dentists, Oxford , Oxford University Press, 2006, pp219 - 231, [Fleming GJP] Book Chapter, 2006

Fleming GJP, Dickens M, Thomas LJ, Harris JJ., In-vitro clinical failure of an all-ceramic crown and connector area of a fixed partial denture using bilayered ceramic specimens: the influence of core to dentine thickness ratio. , Dental Materials, 22, (8), 2006, p771 - 777 Journal Article, 2006

Curtis AR, Wright AJ, Fleming GJP. , The influence of surface modification techniques on the performance of a Y-TZP dental ceramic. , Journal of Dentistry, 34, (3), 2006, p195 - 206 Journal Article, 2006

Fleming GJP, Kenny SM, Barralet JE. , The optimisation of the initial viscosity of an encapsulated glass-ionomer filling material following different mechanical mixing regimes. , Journal of Dentistry, 33, (2), 2006, p155 - 163 Journal Article, 2006

Dowling AH, Stamboulis A, Fleming GJP, The influence of montmorillonite clay reinforcement on the performance of a glass ionomer restorative., Journal of Dentistry , 34, (10), 2006, p802 - 810 Journal Article, 2006

Curtis AR, Wright AJ, Fleming GJP. , The influence of simulated masticatory loading regimes on the bi-axial flexure strength and reliability of a Y-TZP dental ceramic. , Journal of Dentistry, 34, (5), 2006, p317 - 325 Journal Article, 2006

Palin WM, Fleming GJP, Nathwani H, Burke FJT, Randall RC. , In-vitro cuspal deflection and microleakage of maxillary premolars restored with novel low-shrink dental composites., Dental Materials , 21, (4), 2005, p324 - 335 Journal Article, 2005

Palin WM, Fleming GJP, Burke FTJ, Marquis PM, Randall RC. , The influence of short and medium-term water immersion on the hydrolytic stability of novel low-shrink dental composites following medium-term immersion., Dental Materials, 21, (9), 2005, p852 - 863 Journal Article, 2005

Palin WM, Fleming GJP, MR Pintado, Burke FJT, Randall RC, Douglas WH, Marquis PM. , The frictional coefficients and associated wear resistance of a novel low-shrink resin-based composites., Dental Materials, 21, (12), 2005, p1111 - 1118 Journal Article, 2005

Palin WM, Fleming GJP, Marquis PM. , The reliability of standardised flexure strength testing procedures for a light-activated resin-based composite. , Dental Materials, 21, (10), 2005, p911 - 919 Journal Article, 2005

Fleming GJP, El-lakwah SFA, Harris JJ, Marquis PM. , The effect of layer height variation on the bi-axial flexure strength and mode of failure of bilayered dental ceramics. , Dental Materials, 21, (2), 2005, p164 - 171 Journal Article, 2005

Fleming GJP, Nolan L, Harris JJ., The in-vitro clinical failure of all-ceramic crowns and the connector area of fixed partial dentures: the influence of interfacial surface roughness. , Journal of Dentistry, 33, (5), 2005, p405 - 412 Journal Article, 2005

Dobinson M, Fleming GJP, Landini G, Harris JJ. , An in-vitro evaluation of the accuracy of fit of Procera and Empress crowns., The European Journal of Prosthodontic and Restorative Dentistry, 13, (3), 2005, p109 - 114 Journal Article, 2005

Fleming GJP, Hall D, Shortall ACC, Burke FJT. , Cuspal movement and microleakage in premolar teeth restored with posterior filling materials of varying reported volumetric shrinkage values. , Journal of Dentistry , 33, (2), 2005, p139 - 146 Journal Article, 2005

Fleming GJP, Jandu HS, L Nolan, Shaini FJ., The influence of alumina abrasion and cement lute on the strength of a porcelain laminate veneering material. , Journal of Dentistry , 32, (1), 2004, p67 - 74 Journal Article, 2004

Fleming GJP, El-lakwah SFA, Harris JJ, Marquis PM. , The influence of interfacial surface roughness on bilayered ceramic specimen performance. , Dental Materials , 20, (2), 2004, p142 - 149 Journal Article, 2004

Patel HB, Fleming GJP, Burke FJT. , An investigation into the puncture resistance and stiffness in nitrile and latex dental gloves. , British Dental Journal , 196, (11), 2004, p695 - 700 Journal Article, 2004

Addison O, Fleming GJP., The influence of cement lute and thermocycling on the strength of porcelain laminate veneer (PLV) surface preparations. , Dental Materials , 20, (3), 2004, p286 - 292 Journal Article, 2004

Palin WM, Fleming GJP, Burke FJT, Marquis PM, Randall RC., The reliability in flexural strength testing of a novel dental composite. , Journal of Dentistry , 31, (8), 2003, p549 - 557 Journal Article, 2003

Fleming GJP, Farooq AA, Barralett JE., The influence of powder/liquid mixing ratio on the performance of a range of glass-ionomer cements., Biomaterials, 24, (23), 2003, p4173 - 4179 Journal Article, 2003

Addison O, Fleming GJP, Marquis PM. , The influence of thermocycling on the longevity of porcelain laminate veneer (PLV) restorations., Dental Materials , 19, (4), 2003, p292 - 298 Journal Article, 2003

Patel HB, Fleming GJP, Burke FJT. , An initial report on the incidence of pre-existing pinhole defects in nitrile dental gloves., British Dental Journal , 195, (9), 2003, p509 - 512 Journal Article, 2003

Fleming GJP, Narayan O. , The effect of cement type and mixing on the bi-axial fracture strength of cemented aluminous core porcelain discs., Dental Materials , 19, (1), 2003, p69 - 76 Journal Article, 2003

Fleming GJP, Zala D. , An assessment of the properties of encapsulated versus hand-mixed dental restoratives., Operative Dentistry , 28, (2), 2003, p166 - 175 Journal Article, 2003

Palin WM, Fleming GJP, Burke FJT, Marquis PM, Randall RC., Monomer conversion versus flexure strength of a novel dental composite. , Journal of Dentistry , 31, (5), 2003, p341 - 351 Journal Article, 2003

Abbas G, Fleming GJP, Harrington E, Shortall ACC, Burke FJT., Cuspal movement and microleakage in premolar teeth restored with a packable composite cured in bulk or incrementally. , Journal of Dentistry , 31, (6), 2003, p437 - 444 Journal Article, 2003

Grover LM, Knowles JC, Fleming GJP, Barralet JE. , In-vitro ageing of Brushite calcium phosphate cement., Biomaterials, 24, (23), 2003, p4133 - 4141 Journal Article, 2003

Palin WM, Fleming GJP., Low shrink monomers for dental restorations. , Dental Update , 30, (3), 2003, p118 - 122 Journal Article, 2003

Barralet JE, Fleming GJP, Campion C, Harris JJ, Wright AJ., Formation of translucent hydroxyapatite ceramics by sintering in carbon dioxide atmospheres. , Journal of Materials Science , 38, (19), 2003, p3979 - 3993 Journal Article, 2003

Shaini FJ, Fleming GJP, Marquis PM, Shortall ACC., A palladium-free gallium-based alloy: Analysis of composition and microstructure., Dental Materials , 19, (7), 2003, p654 - 662 Journal Article, 2003

Palin WM, Fleming GJP, Marquis PM. , An evaluation of the mechanical properties of 'hydrothermal' dental glass after water immersion and surface polishing., Dental Materials , 19, (2), 2003, p92 - 100 Journal Article, 2003

Skelly AM, Fleming GJP. , Perceptions of a dental career amongst successful applicants for dentistry compared with those of fifth year dental students. , Primary Dental Care , 9, (2), 2002, p41 - 46 Journal Article, 2002

Fleming GJP, Landini G, Marquis PM., Properties of encapsulated and hand-mixed zinc phosphate dental cement. , American Journal of Dentistry , 15, (2), 2002, p91 - 96 Journal Article, 2002

Burke FJT, Fleming GJP, Nathansan D, Marquis PM. , Are adhesive technologies needed to support ceramics? An assessment of the current evidence., Journal of Adhesive Dentistry , 4, (1), 2002, p7 - 22 Journal Article, 2002

Bhamra G, Palin WM, Fleming GJP., The effect of surface roughness on the flexure strength of an alumina reinforced all-ceramic crown material., Journal of Dentistry , 30, (4), 2002, p153 - 160 Journal Article, 2002

Burke FJT, Fleming GJP, Owen FJ, Watson DJ. , Materials for the restoration of primary teeth 2: Glass Ionomer derivatives and compomers. , Dental Update , 29, (1), 2002, p10 - 17 Journal Article, 2002

Golding MA, Palmer GD, Fleming GJP. , Preference for venepuncture site: should the patient be consulted?, Dental Update , 29, (5), 2002, p239 - 243 Journal Article, 2002

Fleming GJP, Burke FJT, Watson DJ, Owen FJ. , Materials for restoration of primary teeth 1: Conventional materials and early glass ionomers. , Dental Update , 28, (10), 2001, p486 - 491 Journal Article, 2001

Fleming GJP, Shelton RM, Landini G, Marquis PM., The influence of mixing ratio on the toughening mechanisms of a hand-mixed zinc phosphate dental cement., Dental Materials , 17, (1), 2001, p14 - 20 Journal Article, 2001

Shaini FJ, Fleming GJP, Marquis PM, Shortall ACC., A comparison of the mechanical properties of a gallium-based alloy with a spherical high-copper amalgam., Dental Materials , 17, (2), 2001, p142 - 148 Journal Article, 2001

Tippuni AR, Fleming GJP., The effect of antiretroviral therapy on the prevalence of oral manifestations in HIV-infected patients: A UK study., Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics , 92, (6), 2001, p623 - 628 Journal Article, 2001

Palin WM, Fleming GJP, Marquis PM., An evaluation of the technique sensitivity of a hydrothermal low-fusing dental ceramic., Journal of Dentistry , 29, (6), 2001, p443 - 449 Journal Article, 2001

Boyle CA, Horner K, Coulthard P, Fleming GJP., Multiple Stafne bone concavities: a diagnostic dilema. , Dental Update , 27, (10), 2000, p494 - 497 Journal Article, 2000

Boyle CA, Manley MCG, Fleming GJP., Oral midazolam for adults with learning disabilities., Dental Update , 27, (4), 2000, p190 - 192 Journal Article, 2000

Fleming GJP, Shaini FJ, Marquis PM. , An assessment of the influence of mixing induced variability on the bi-axial flexure strength of dentine porcelain discs and the implications for laboratory testing of porcelain specimens., Dental Materials , 16, (2), 2000, p114 - 119 Journal Article, 2000

Craig DC, Boyle CA, Fleming GJP, Palmer P. , A sedation technique for implant and periodontal surgery., Journal of Clinical Periodontology , 27, (12), 2000, p955 - 959 Journal Article, 2000

Palmer GD, Fleming GJP. , The management of occupational exposures to blood and saliva in dental practice., Dental Update , 27, (7), 2000, p318 - 324 Journal Article, 2000

Fleming GJP, Marquis PM, Shortall ACC., The influence of clinically induced variability on the distribution of compressive fracture strengths of a hand-mixed zinc phosphate dental cement., Dental Materials , 15, (2), 1999, p87 - 97 Journal Article, 1999

Fleming GJP, Shelton RM, Marquis PM., The influence of clinically induced variability on the bi-axial fracture strength of cemented aluminous core porcelain discs. , Dental Materials , 15, (1), 1999, p62 - 70 Journal Article, 1999

Fleming GJP, Shelton RM, Marquis PM., The influence of clinically induced variability on the bi-axial fracture strength of aluminous core porcelain discs., Journal of Dentistry , 27, (8), 1999, p587 - 594 Journal Article, 1999

Fleming GJP, Shortall ACC, Shelton RM, Marquis PM., Encapsulated verses hand-mixed zinc phosphate dental cement., Biomaterials , 20, (22), 1999, p2147 - 2153 Journal Article, 1999

Non-Peer-Reviewed Publications

Cao X, Fleming GJP, Addison O, The impact of resin-coating on sub-critical crack extension in a porcelain laminate veneer material, Dental Materials, 33, (5), 2017, p498 - 504 Journal Article, 2017

Research Expertise

Projects

  • Title
    • DENTAL glass-ionomer restoratives: Development of an Enhanced Novel Tailored Aesthetic Ligand-based glass-ionomer restorative.
  • Summary
    • Recent research suggests that single surface amalgam restorations produce a survival probability of 58% after ten years compared with 43 and 38%, respectively for resin-based composites (RBCs) (placed in Class III, IV and V cavities) and glass-ionomers (GIs) (placed in Class III and V cavities). Dental amalgam relies on mechanical interlocking for adhesion and the destruction of sound tooth structure is necessary with re-intervention in one in three cases being extraction or crowning. In addition, patient demand for the aesthetic treatment combined with the fear of mercury toxicity limit the appeal of amalgam. RBCs are aesthetic but time consuming, technique sensitive and require a series of preconditioning treatments of the tooth structure to ensure adhesion. The development of simplified bonding systems have not been as successful as expected despite the enormous research interest, with RBC performance reduced year on year since 1996. This proposed project aims to deliver a cost effective and predictable novel aesthetic posterior filling material to be placed in minimal intervention cavities with no associated loss of sound tooth structure. It is suggested that in principle re-intervention of like with like (GI with GI) could allow a tooth to survive indefinitely and eliminate the expense of crowing providing a major cost saving for the patient or the relevant health service provider namely the Health Services Executive. In short, the immediate beneficiaries are likely to be general dental practitioners (GDPs) and their patients who could take advantage of an enhanced GI restorative, thereby promoting minimal intervention techniques which would result in the preservation of sound tooth structure. The preservation of sound tooth structure would significantly impact on the quality of life of the general population as the extensive loss of natural dentition would result in extended patient visits to GDPs an in cases of extreme tooth loss would result in the patient requiring unsightly dentures which would significantly impact upon their quality of life. From a commercial viewpoint the ideal posterior filling material should be aesthetic and adhesive, qualities that only GIs possess and therefore an enhanced GI restorative would be an attractive commercial alternative to dental amalgam and RBCs. The development of advanced synthetic approaches and modern characterization methods for clinically applicable novel dental restorative glass-ionomer materials will result in a unique expertise of skilled researchers and is extremely valuable for the success in future research or academic careers. Conventional technical preparation methods often suffer not just from high costs but also from a reduced ability to produce multifunctional organic/inorganic composite structures and materials with hierarchical order; features that attribute unique mechanical and physiochemical properties to biomaterials including dental restorative materials. This project offers the opportunity for the Research Team at the Materials Science Unit to cement its place as one of the leading developers of dental materials worldwide. In short this collaboration between a Lecturer in Inorganic and Synthetic Materials Chemistry with a Senior Lecturer in Dental Materials Science offers the first step in a collaborative process that would see closer integration between two distinct scientific disciplines not noted for collaborations.
  • Funding Agency
    • Science Foundation Ireland
  • Date From
    • 01/04/2013
  • Date To
    • 31/03/2017
  • Title
    • Implications for patient therapy of dental resin restoratives: Does simplifying the curing protocol increase patient risk?
  • Summary
    • While patient demand for aesthetic restorative treatment of posterior teeth combined with the enhanced public awareness of mercury toxicity from silver/grey dental amalgam restorations have resulted in the increased use of tooth-coloured resin-based composite (RBC) materials over the past two decades. Recent support for legislation from the European Commission to restrict the manufacture, use and disposal of mercury-containing materials has uncovered new challenges for dental practitioners and patients alike. Despite developments in light curing technology and RBC materials, the clinical performances of RBCs has not improved over a decade. Poor polymerisation protocols manifest as RBC restorations with inadequate mechanical and biological properties have resulted in significantly increased restoration failure rates and systemic health concerns, respectively even when compared with mercury-containing dental amalgams. Recommendations for the determination of a dental materials' biocompatibility status using ISO 7405 is wanting at best and perilous to patient health at worst. Our patient-focused multi-disciplinary research proposal offers an exceptional opportunity to strategically target and correct concerns with RBC eluents, ubiquitous throughout modern restorative dentistry. We have produced a primary human cell-based oral-mucosal-model, defined by distinct epithelial and connective tissue layers, metabolically viable and histologically resembling native human oral-mucosa. Our published data has highlighted significant cytotoxicity of nickel-containing base-metal alloys routinely used in dentistry and we believe that critically the activation of the innate immune response by RBC eluents can be demonstrated by initiation of proinflammatory responses in methacrylate and non-methacrylate-sensitised patients. It is anticipated that the multi-disciplinary patient-orientated research will provide a meaningful evidence-based questionnaire and clinical protocol for the Dublin Dental University Hospital (DDUH) which could be introduced across Dental Schools, Health Service Executive Institutions and Primary Care Dental Practices within Ireland and beyond. This would result in a research-driven modification to routine restorative dental treatment provision in methacrylate and non-methacrylate-sensitised patients. The patient-orientated approach involves an appropriate risk appraisal of the onset of inflammatory tissue responses by combining expertise in Materials Science and Cellular and Molecular Biology will be undertaken in a clinical environment. The main objective is to optimise clinical treatment protocols which will significantly reduce clinical re-intervention with an obvious cost saving to the patient and ultimately improve the patients' dental experience.
  • Funding Agency
    • Health Research Board
  • Date From
    • 01/10/2013
  • Date To
    • 30/09/2016
  • Title
    • The strengthening mechanism of resin-based luting cements to dental ceramics
  • Summary
    • The dental literature is replete with fracture resistance studies of all-ceramic materials with the 'crunch-the-crown' load-to-failure test routinely used despite the failure mode which involves indenter contact surface damage failing to replicate clinically relevant sub-surface radial fracture. Additionally, load-to-failure data provides no information on stress patterns within complex crown geometries and comparisons between studies are impossible owing to variable testing protocols. Testing geometric planar specimens allows for the calculation of failure stresses using bending theory. By employing standardised planar geometries, sample preparation and loading protocols, comparisons between materials and investigators are possible. However, planar data provides a conservative measure of fracture behaviour and fails to account for geometric factors which may modify the stressing patterns, or defect populations within a complex body such as a loaded restoration. Finite element analysis (FEA) methodologies have been widely used in dentistry as virtual case studies employing the adaptive capabilities of parametric simulations to assess sensitivities to discrete changes in variables defining the model, including material, dimensional and/or geometric parameters. While virtual case studies are insightful, the usefulness of FEA simulations are governed by the limitations of specific features of the model investigated. By implication features unspecified in the simulation cannot be manifest as determinants of the factors investigated. The idealisations employed in an FEA simulation may be detrimental by inaccurately representing material behaviour. Measured dental-ceramic strength depends upon the statistical distribution and configuration of defects thereby requiring a probabilistic approach. Whilst FEA methods can incorporate statistical elements, empirical measurements are essential to determine how geometric variability influences a statistical defect population in the fabricated complex shape. May et al. (2012) compared an FEA model derived with the probabilistic determination of boundary conditions, which included predicted failure criteria from experimental data, to investigate representative 'crunch-the-crown' load-to-failure testing. The assumed failure criteria was established experimentally but was associated with an 'uncertainty' in the FEA results, thereby limiting the authors confidence in the approach. Simplified non-planar geometries (curved-discs), with a single radius-of-curvature, have been proposed to examine the impact of geometric factors on radial fracture. However, in the absence of analytical solutions to describe the stress distribution in curved-discs tested in biaxial flexure, we aimed to investigate the influence of non-planar geometries on the maximum-principal-stress. Radii-of-curvature analogous to elements of complex dental geometries were investigated and the FEA simulation was integrated with load-to-failure testing as a surrogate solution to calculate the maximum-principal-stress at failure.
  • Funding Agency
    • Trinity College Dublin
  • Date From
    • 01/04/2010
  • Date To
    • 30/09/2013
  • Title
    • The development of improved glass-ionomer restoratives
  • Summary
    • Glass Ionomer Cements (GICs) are restorative dental materials consisting of two separate components - a glass powder and a polymeric liquid element. GICs are routinely employed in dental applications as cavity linings and bases, luting cements and as anterior filling materials especially in paediatric dentistry due to their minimally invasive nature. More recently, there is an increased interest in the use of glass-ionomer restoratives as posterior filling materials due to aesthetic demands of patients and the potential fear of mercury toxicity from dental amalgams. Unfortunately, conventional GIC cement formulations are not advocated for large messio-occlusal-distal (MOD) cavities due to their reduced mechanical properties (compressive fracture strength, fracture tougness and wear resistance) when compared with dental amalgam. The purpose of the study will be to validate the hypothesis that the mechanical properties of conventional GI restoratives can be improved to produce increased performance compared with conventional GI restoratives when placed in the posterior region of the mouth. The experimental GI restoratives will also be trailed for clinical performance, namely compressive fracture strength, fracture toughness and wear resistance. Consequently by targeting and eliminating the key failure mechanisms of posterior GI restorative and filling materials it is proposed that an experimental, commercially viable reinforced experimental GI restorative may improve conventional GI restorative performance in the mouth.
  • Funding Agency
    • Science Foundation Ireland
  • Date From
    • 01/04/2007
  • Date To
    • 31/03/2011

Keywords

Biomaterials; CARPROFEN; CELL CYTO-TOXICITY; CEMENT; Ceramic materials and powders; CERAMICS; Composite materials; Corrosion; DENTAL RESTORATIVE MATERIALS; Dentistry; Metallurgy; Polymers

Recognition

Awards and Honours

Young Investigator Distinguished Scientist Award for the International Association of Dental Research 2004

Fellow of the Academy of Dental Materials (FADM) 2004

Fellow of Trinity College Dublin (FTCD) 2010

Memberships

Member of the International Association of Dental Research (IADR)

Member of the IADR (Irish Division)

Member of the British Society for Dental Research (BSDR)

Member of the Academy of Dental Materials

Member of the Dental Materials Panel of the UK

Member of the International Dental Materials Group (DMG) and British DMG