Principal Investigators
Click a heading to see Principal Investigators within each school.
School of Biochemistry & Immunology +
Prof. Luke O'Neill
Chair Of Biochemistry, School of Biochemistry and Immunology, School of Biochemistry and Immunology
Research areas: Innate immunity and inflammatory diseases.
e: laoneill@tcd.ie | t: +353-1-896 2439
w: Prof. Luke O'Neill's homepage
Dr Gavin Davey
Senior Lecturer, School of Biochemistry and Immunology
Research areas: Molecular and cellular mechanisms that underlie neurodegeneration in the brain
e: gdavey@tcd.ie | t: +353-1-896 1853/896 8408
w: Dr Gavin Davey's homepage
Prof. Kingston Mills
Professor, School of Biochemistry and Immunology
Research areas: T cells and immune regulation, relevant to infection, autoimmunity and cancer.
e: kingston.mills@tcd.ie | t: +353-1-896 3573
w: Prof. Kingston Mills's homepage
Prof Cliona O'Farrelly
Chair in Comparative Immunology, School of Biochemistry and Immunology
Research areas: Regional Immunity: Role in Liver, Gut &Uterine Pathology. Comparative Immunology
e: cliona.ofarrelly@tcd.ie | t: +353-1-896 3175
w: Prof Cliona O'Farrelly's homepage
Prof Clive Williams
Associate Professor , School of Biochemistry and Immunology
Research areas: Cancer Drug Discovery
e: clive.williams@tcd.ie | t: +353-1-896 3964
w: Prof Clive Williams's homepage
Prof Andrew Bowie
Associate Professor, School of Biochemistry and Immunology
Research areas: Viral Immune Evasion
e: agbowie@tcd.ie | t: +353-1-896 2435
w: Prof Andrew Bowie's homepage
Dr Emma Creagh
Lecturer, School of Biochemistry and Immunology
Research areas: Research interests in the link between Cancer and Inflammation. The role of inflammatory caspases and their target proteins in intestinal inflammation during Inflammatory Bowel Disease (IBD) and Colorectal Cancer.
e: ecreagh@tcd.ie | t: +353-1-896 2539
w: Dr Emma Creagh's homepage
Prof Martin Caffrey
Personal Chair, School of Biochemistry and Immunology
Research areas: Crystallizing membrane proteins
e: martin.caffrey@tcd.ie | t: +353-1-896 4253
w: Prof Martin Caffrey's homepage
Dr Colm Cunningham
Research lecturer, School of Biochemistry and Immunology
Research areas: Neurodegeneration and neuroinflammation and the role of microglia in these processes
e: colm.cunningham@tcd.ie | t: +353-1- 896 8528
w: Dr Colm Cunningham's homepage
Dr Aisling Dunne
Lecturer, School of Biochemistry and Immunology
Research areas: Elucidating the mechanisms involved in TLR/NLR activation as well as the identification of novel agonists from pathogens such as Bordetella pertussis
e: aidunne@tcd.ie | t: +353-1-896 2437
w: Dr Aisling Dunne's homepage
Dr. David Finlay
Lecturer, School of Biochemistry and Immunology
Research areas: Control of Cancer Metabolism.
e: finlayd@tcd.ie | t: +353-1-896 3564
w: Dr. David Finlay's homepage
Dr Jean Fletcher
Lecturer, School of Biochemistry and Immunology
Research areas: Immune regulation in human disease
e: jean.fletcher@tcd.ie | t: +353-1-896 4437
w: Dr Jean Fletcher's homepage
Dr Clair Gardiner
Senior Lecturer, School of Biochemistry and Immunology
Research areas: How human NK cells mediate their functions as part of the overall immune response
e: gardinec@tcd.ie | t: +353-1-896 1614
w: Dr Clair Gardiner's homepage
Dr Julie Kelly
Research Senior Lecturer, School of Biochemistry and Immunology
Research areas: Understanding the roles of neuropeptides in the central nervous system (CNS)
e: kellyja@tcd.ie | t: +353-1-8968409
w: Dr Julie Kelly's homepage
Dr Vincent Kelly
Lecturer, School of Biochemistry and Immunology
Research areas: The role of transfer RNA (tRNA) modifications and their role in eukaryotic development and cancer
e: kellyvp@tcd.ie | t: +353-1-896 3507
w: Dr Vincent Kelly's homepage
Dr Amir Khan
Lecturer, School of Biochemistry and Immunology
Research areas: X-Ray Crystallography .
e: amirrafk@tcd.ie | t: +353-1-896 3868
w: Dr Amir Khan's homepage
Dr Ed Lavelle
Lecturer, School of Biochemistry and Immunology
Research areas: Vaccine adjuvants and mucosal vaccine development
e: lavellee@tcd.ie | t: +353-1-896 2488
w: Dr Ed Lavelle's homepage
Dr. David Lloyd
Hitachi Senior Lecturer, School of Biochemistry and Immunology
Research areas: The application of computational modelling to augment the drug design process
e: lloyddg@tcd.ie | t: +353-1-896 2904
w: Dr. David Lloyd's homepage
Dr Tim Mantle
Lecturer, School of Biochemistry and Immunology
Research areas: Fundamental aspects of enzyme action
e: tmantle@tcd.ie | t: +353-1-896 1612
w: Dr Tim Mantle's homepage
Dr Rachel McLoughlin
Lecturer, School of Biochemistry and Immunology
Research areas: Understanding the interaction of bacteria and the molecules they express, with the host's immune system
e: rachel.mcloughlin@tcd.ie | t: +353-1-896 2526
w: Dr Rachel McLoughlin's homepage
Dr Ken Hun Mok
Lecturer, School of Biochemistry and Immunology
Research areas: Probing the attainment of natively- or alternatively- folded three-dimensional molecular structures
e: mok1@tcd.ie | t: +353-1-896 3190
w: Dr Ken Hun Mok 's homepage
Dr Anne Molloy
Research Senior Lecturer, School of Biochemistry and Immunology
Research areas: Vitamins in one-carbon metabolism
e: amolloy@tcd.ie | t: +353-1-896 1616
w: Dr Anne Molloy's homepage
Dr Derek Nolan
Lecturer, School of Biochemistry and Immunology
Research areas: Molecular Parasitology
e: denolan@tcd.ie | t: +353-1-896 2455
w: Dr Derek Nolan's homepage
Dr Richard Porter
Senior Lecturer, School of Biochemistry and Immunology
Research areas: The molecular basis of basal metabolic rate and how metabolism is controlled in mammals
e: rkporter@tcd.ie | t: +353-1-896 1617
w: Dr Richard Porter's homepage
Dr Daniela Zisterer
Senior Lecturer , School of Biochemistry and Immunology
Research areas: Molecular and cellular mechanisms that underlie apoptotic cell death and in understanding how deregulated apoptosis leads to cancer
e: dzistrer@tcd.ie | t: +353-1-896 1628
w: Dr Daniela Zisterer's homepage
Jeff O'Sullivan
School of Biochemistry and Immunology/School of Dental Science
Research areas: Oral/mucosal dysplasia. ROS generation/cell metabolism in (pre)cancerous cells. Role of inflammation in (oral/mucosal) cancer progression. Amine Oxidase function in cancer/inflammation. Novel Amine Oxidase inhibitors
Prof. Richard Reilly
Professor of Neural Engineering and Ageing, School of Bioengineering
Research areas:
Dr Daniel Kelly
Assistant Professor, School of Bioengineering
Research areas: Computational and experimental mechanobiology
e: kellyd9@tcd.ie | t: +353 1 8963947
w: Dr Daniel Kelly's homepage
Dr Conor Buckley
Assistant Professor (Tissue Engineering), School of Bioengineering
Research areas: Development of strategies to regenerate the intervertebral disc (IVD) and articular cartilage. Other research areas include design and development of bioreactor based systems, tissue engineering, nutrient micro-environments, biomaterial interactions and 3D scaffold construct technology
e: conor.buckley@tcd.ie | t: +353 1 6795554
w: Dr Conor Buckley's homepage
Dr Edmund Lalor
Assistant Professor, School of Bioengineering
Research areas:
e: edlalor@tcd.ie | t: +353-1-8961743
w: Dr Edmund Lalor's homepage
Dr Bruce Murphy
Assistant Professor in Biomechanical Engineering, School of Bioengineering
Research areas:
e: bruce.murphy@tcd.ie | t: +353 1 8968503
w: Dr Bruce Murphy's homepage
Dr. Ciaran Simms
Lecturer, School of Bioengineering
Research areas: Injury biomechanics, soft tissue mechanics and medical device design
e: csimms@tcd.ie | t: +353 1 8963768
w: Dr. Ciaran Simms's homepage
Dr Kevin O Kelly
Deputy Director Trinity Centre Bioengineering, Associate Professor, School of Bioengineering
Research areas:
e: okellyk@tcd.ie | t: +353 1 8961367
w: Dr Kevin O Kelly's homepage
Dr Alice Witney
Assistant Professor, School of Bioengineering
Research areas:
e: awitney@tcd.ie | t: +353 1 8961019
w: Dr Alice Witney's homepage
Prof. Veronica Campbell
Associate Professor, School of Bioengineering
Research areas:
e: vacmpbll@tcd.ie | t: +353 1 8961192
w: Prof. Veronica Campbell's homepage
Prof. Mathias O. Senge
Professor, Chair of Organic Chemistry, School of Chemistry
Research areas: Cancer Research
e: sengem@tcd.ie | t: +353 1 896 8537
w: Prof. Mathias O. Senge's homepage
Prof. Thorfinnur Gunnlaugsson
Senior Sophister Coordinator, School of Chemistry
Research areas: Cancer Research
e: thorri.g@tcd.ie | t: +353 1 896 3459
w: Prof. Thorfinnur Gunnlaugsson's homepage
Prof. Stephen Connon
Professor in Synthetic Chemistry, School of Chemistry
Research areas: Cancer Chemotherapy, Catalysis, Cyclin, Kinase Complex, Organic-Synthesis, Organometallics, Tetracycline
e: connons@tcd.ie | t: +353 1 896 1306
w: Prof. Stephen Connon's homepage
Prof. David Grayson
Associate Professor &Head of School, School of Chemistry
Research areas: Development of new methods for organic synthesis; synthesis of complex natural products, especially medium-ring and macrocyclic lactones; cycloaddition chemistry of vinylic sulfones; chemistry of sulfonyl-stabilised anions; chiral auxiliaries and reagents derived from monoterpenoids; heterocyclic chemistry, especially the chemistry of 4-dimethylaminopyridine N-oxide and some homochiral derivatives
e: dgrayson@tcd.ie | t: +353 1 896 1423
w: Prof. David Grayson's homepage
Prof. Isabel Rozas
Associate Professor , Director of Teaching and Learning (Postgraduate), School of Chemistry
Research areas: Cancer Research
e: rozasi@tcd.ie | t: +353 1 896 3731
w: Prof. Isabel Rozas's homepage
Dr Michael Southern
Lecturer in Chemistry (Medicinal/Organic) Course Director of the B.A. (Mod) in Chemistr, School of Chemistry
Research areas: Drug discovery and development, neurochemistry, the interface of chemistry and biology and synthetic organic chemistry
e: southerj@tcd.ie | t: +353 1 896 3411
w: Dr Michael Southern's homepage
Dr Eoin Scanlan
Lecturer, International Coordinator, School of Chemistry
Research areas: Development of novel synthetic methodology for the construction of oligosaccharides and glycoconjugates, the synthesis of carbohydrate-based therapeutics for treatment of diseases, the synthesis of immunogenic carbohydrates and the synthesis of glycoconjugates for bio-imaging
e: eoin.scanlan@tcd.ie | t: +353 1 896 2514
w: Dr Eoin Scanlan's homepage
Dr. Enda Bergin
Lecturer, School of Chemistry
Research areas: Catalysis, Environmental Chemistry, Medicinal Chemistry, Organic chemistry
e: ebergin@tcd.ie | t: +353 1 896 2514
w: Dr. Enda Bergin's homepage
Dr Silvia Giordani
Research Lecturer-SFI PIYRA, School of Chemistry
Research areas: Design, synthesis, and characterization of a range of molecular switches and nanomaterials that are intended for applications in smart and responsive bio-related nanotechnologies
e: giordans@tcd.ie | t: +353 1 896 1422
w: Dr Silvia Giordani's homepage
Prof. Padraic Fallon
Stokes Professor, School of Medicine
Research areas: My research involves two overlapping translational immunology themes. i. The use of mouse models to study pathogen modulation of human inflammatory diseases. ii. Immune phenotyping of patients, in particular children, with inflammatory diseases such as atopic dermatitis and pulmonary fibrosis. Research aims to elucidate new mechanism of modulation of immunity that can alter inflammation and have therapeutic potential. Collaborative activity involves the phenotyping of new transgenic mice. The main diseases addressed are allergic lung and skin inflammation and inflammatory bowel disease. A growing emphasis is applying extensive expertise in animal models of human inflammatory diseases and general pathophysiology of inflammation to functional analysis of new therapeutic molecules/strategies with clinical collaborators and Pharma.
e: pfallon@tcd.ie | t: +353 1 896 3267
w: Prof. Padraic Fallon's homepage
Prof. Orla Hardiman
Clinical Professor, School of Medicine
Research areas: Chronic Disease, Chronic Illness, Dementia, Disability, Neurodegeneration, Neuroimaging
e: hardimao@tcd.ie | t: +353 1 896 4496
w: Prof. Orla Hardiman's homepage
Prof. Mark Little
Professor/Consultant of Nephrology, School of Medicine
Research areas:
e: mlittle@tcd.ie | t: +353 1 896 3844
w: Prof. Mark Little's homepage
Prof. Kumlesh Dev
Professor of Neuroscience, School of Medicine
Research areas: Drug Targets, Glutamate Receptors, Multiple Sclerosis, Neuroscience, Parkinson's Disease, Protein-Protein Interactions, Receptor Trafficking, Sphingosine 1-phosphate receptors
e: devk@tcd.ie | t: +353 1 896 4180
w: Prof. Kumlesh Dev's homepage
Dr. Neil G. Docherty
Lecturer, School of Medicine (Physiology)
Research Areas: Pathophysiology and treatment of chronic inflammatory and fibrotic diseases of the kidney and gastrointestinal tract.
e: dochertn@tcd.ie | t: +353 1 896 2076
w: Dr. Neil Docherty's homepage
Prof Marek Radomski
Head of School & Chair of Pharmacology (1979), School of Pharmacy and Pharmaceutical Sciences
Research areas: Interaction of cancer cells with microenvironment Blood-born mechanisms of carcinogenesis Mechanisms of anticancer drug resistance Nanopharmacology of blood cell-cancer interactions
e: marek.radomski@tcd.ie | t: +353 1 896 2819
w: Prof Marek Radomski's homepage
Dr Astrid Sasse
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Development of small ligands for G-Protein coupled receptors (e.g., histamine H3/H4 receptor) as well as the genetic linkage of those receptors to psychiatric disorders
e: sassea@tcd.ie | t: +353 1 896 2797
w: Dr Astrid Sasse's homepage
Dr Andrew Harkin
Senior Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Drug development for psychiatric disorders and safety evaluation of drugs affecting the central nervous system
e: aharkin@tcd.ie | t: +353 1 896 2807
w: Dr Andrew Harkin's homepage
Dr Neil Frankish
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Novel drug development in the areas of allergy and inflammation, with a particular interest in inflammatory bowel disease
e: nfrnkish@tcd.ie | t: +353 1 896 2825
w: Dr Neil Frankish's homepage
Dr Lorraine O'Driscoll
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Translational cancer research
e: lodrisc@tcd.ie | t: +353 1 896 2822
w: Dr Lorraine O'Driscoll's homepage
Dr Carsten Ehrhardt
Senior Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Transport mechanisms and cell physiology of alveolar and bronchial epithelial barriers and the development of advanced drug delivery systems for pulmonary targeting.
e: carsten.ehrhardt@tcd.ie | t: +353 1 896 2441
w: Dr Carsten Ehrhardt's homepage
Dr Fabio Boylan
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Ethnopharmacological information of medicinal plants from South America, Europe and Asia. Pharmacological targets are mainly related to inflammation, pain, cancer and central nervous system.
e: fabio.boylan@tcd.ie | t: +353 1 896 4154
w: Dr Fabio Boylan's homepage
Dr Helen Sheridan
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Identifying problems and proposing solutions by applying functional genomic approaches; establishing guidelines and priority areas for the future
e: hsheridn@tcd.ie | t: +353 1 896 2828
w: Dr Helen Sheridan's homepage
Dr John Walsh
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Allergy, cancer, malaria and educational research
e: jjwalsh@tcd.ie | t: +353 1 896 2806
w: Dr John Walsh's homepage
Dr Maria Jose Santos-Martinez
Ussher Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas:
e: mariajose.santos@tcd.ie | t: +353 1 896 4281
w: Dr Maria Jose Santos-Martinez's homepage
Dr Lidia Tajber
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Cancer Research
e: lidia.tajber@tcd.ie | t: +353 1 896 2787
w: Dr Lidia Tajber's homepage
Dr Anne Marie Healy
Director of Teaching &Learning (Undergraduate) , School of Pharmacy and Pharmaceutical Sciences
Research areas: Cancer Research
e: healyam@tcd.ie | t: +353 1 896 1444
w: Dr Anne Marie Healy's homepage
Dr. Deirdre D'Arcy
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Clinical Pharmacokinetics - patient and disease related effects on distribution and elimination, and PKPD metrics, pharmacokinetic clinical trials Dissolution and drug release - dissolution modelling, assessment of dissolution/release properties of preformulated and formulated API
e: ddarcy@tcd.ie | t: +353 1 896 2785
w: Dr. Deirdre D'Arcy's homepage
Prof. Mary Meegan
Associate Professor, School of Pharmacy and Pharmaceutical Sciences
Research areas: Cancer Research
e: mmeegan@tcd.ie | t: +353 1 896 2798
w: Prof. Mary Meegan's homepage
Dr John Gilmer
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Study of chemico-biological interactions of bile acids and effects on cell viability and proliferation; mechanisms of bile acid uptake in esophageal cells; design of bile acid-based chemo-preventative and therapeutic agents; bile acid activation of GR Inhibition of tumour cell - platelet interactions by aspirin analogs and prodrugs Design of selective MMP inhibitors and hybrid inhibitors of MMP secretion Chemical approaches to targeting of COX-2 inhibitors for chemoprevention
e: gilmerjf@tcd.ie | t: +353 1 896 2795
w: Dr John Gilmer's homepage
Dr Carlos Medina
Lecturer, School of Pharmacy and Pharmaceutical Sciences
Research areas: Research interests: cancer, inflammatory bowel disease, nanoparticle-based therapeutics Involvement of matrix metalloproteinases in cancer and inflammatory bowel disease
e: carlos.medina@tcd.ie | t: +353 1 896 2823
w: Dr Carlos Medina's homepage
Dermot Kelleher
School of Medicine
Research areas:
Paul Tierney
School of Medicine
Research areas:
Veronica Campbell
School of Medicine
Research areas: Apoptosis, Biology, Biomedical sciences, Intra and intercellular signalling, Neurochemistry and neuropharmacology, Neurodegeneration, Neuropharmacology, Physiology
Aine Kelly
School of Medicine
Research areas: Ageing, memory and other cognitive processes, Neurochemistry and neuropharmacology, Neurodegeneration, Neurophysiology, Neuroscience, Physiology
Mikel Egana
School of Medicine
Research areas: AGE-RELATED IMPAIRMENT, CARDIOVASCULAR RISK-FACTORS, Clinical Trial, DIABETES-MELLITUS, EXERCISE TOLERANCE, Exercise physiology, Insulin, Musculoskeletal System, Obesity POSTURE, Sports Medicine
Alice Witney
School of Medicine
Research areas: Sensory-Motor Integration; Neuromodulation
Roger Anwyl
School of Medicine
Research areas: Neurophysiology, electrophysiology and neurological disease models. Our group studies the effects of natural and synthetic agents on neurological conditions with a particular focus on Alzheimer's disease. We study long-term potentiation effects and synaptic transmission for various receptor sites, including Glutamate Metabotropic receptors. Our group also examines the effects of pharmacological therapeutic agents and neurotoxins and their effects on synaptic plasticity and neuronal repair
Marina Lynch
School of Medicine
Research areas: Age related diseases, Aging/Gerontology, Antiinflammatory Cytokines, Brain, HIPPOCAMPUS, Inflammation, POLYUNSATURATED FATTY ACIDS, PROINFLAMMATORY CYTOKINES, SYNAPTIC PLASTICITY
Thomas Connor
School of Medicine
Research areas: Adenosine, Alzheimer's Disease, Antidepressants, Anxiety, Astrocyte, Behaviour, CREB, Caffeine, Catecholamine, Cytokine, Depression, Drug Abuse, Ecstasy, Glucocorticoid, Growth factor, IL-10, IL-1ra, Immune System, Immunity, Inflammation, MDMA (Ecstasy), Microglia, Multiple Sclerosis, Neurodegeneration, Neuroimmunology, Neurotoxicity, Noradrenaline, Serotonin, Stress, cAMP
