TCIN PI Publications 2007-2009

Prof. Roger Anwyl

Wang Q.W., Rowan M.J. & Anwyl R. (2009) Inhibition of LTP by beta-amyloid is prevented by activation of beta2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway. Neurobiol Aging, 30, 1608-13.

Klyubin I., Wang Q., Reed M. N., Irving E. A., Upton N., Hofmeister J., Cleary J. P., Anwyl R. & Rowan M. J. (2009) Protection against Abeta-mediated rapid disruption of synaptic plasticity and memory by memantine. Neurobiol Aging.

Welsby P. J., Rowan M. J. & Anwyl R. (2009) Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus. Eur J Neurosci, 29, 65-75.

Harney S. C., Jane D. E. & Anwyl R. (2008) Extrasynaptic NR2D-containing NMDARs are recruited to the synapse during LTP of NMDAR-EPSCs. J Neurosci, 28, 11685-94.

Ryan B., Musazzi L., Mallei A., Tardito D., Gruber S. H., El Khoury A., Anwyl R., Racagni G., Mathe A. A., Rowan M. J. & Popoli M. (2009) Remodelling by early-life stress of NMDA receptor-dependent synaptic plasticity in a gene-environment rat model of depression. Int J Neuropsychopharmacol, 12, 553-9.

Ryan B. K., Anwyl R. and Rowan M. J. (2008) 5-HT2 receptor-mediated reversal of the inhibition of hippocampal long-term potentiation by acute inescapable stress. Neuropharmacology 55, 175-182.

Hayes J., Li S., Anwyl R. and Rowan M. J. (2008) A role for protein kinase A and protein kinase M zeta in muscarinic acetylcholine receptor-initiated persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 151, 604-612.

Klyubin I., Betts V., Welzel A. T., Blennow K., Zetterberg H., Wallin A., Lemere C. A., Cullen W. K., Peng Y., Wisniewski T., Selkoe D. J., Anwyl R., Walsh D. M. and Rowan M. J. (2008) Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization. J Neurosci 28, 4231-4237.

Kotilinek L. A., Westerman M. A., Wang Q., Panizzon K., Lim G. P., Simonyi A., Lesne S., Falinska A., Younkin L. H., Younkin S. G., Rowan M., Cleary J., Wallis R. A., Sun G. Y., Cole G., Frautschy S., Anwyl R. and Ashe K. H. (2008) Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity. Brain 131, 651-664.

Wang Q. W., Rowan M. J. and Anwyl R. (2008) Inhibition of LTP by beta-amyloid is prevented by activation of beta2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway. Neurobiol Aging.

Wu J., Harney S., Rowan M. J. and Anwyl R. (2008) Involvement of group I mGluRs in LTP induced by strong high frequency stimulation in the dentate gyrus in vitro. Neurosci Lett 436, 235-238.

Amico F., Spowart-Manning L., Anwyl R. and Rowan M. J. (2007) Performance- and task-dependent effects of the dopamine D1/D5 receptor agonist SKF 38393 on learning and memory in the rat. Eur J Pharmacol 577, 71-77.

Rowan M. J., Klyubin I., Wang Q., Hu N. W. and Anwyl R. (2007) Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction. Biochem Soc Trans 35, 1219-1223.

Wang Q., Klyubin I., Wright S., Griswold-Prenner I., Rowan M. J. and Anwyl R. (2007) alphav integrins mediate beta-amyloid induced inhibition of long-term potentiation. Neurobiol Aging.

Welsby P. J., Rowan M. J. and Anwyl R. (2007) Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP. Neuropharmacology 53, 188-195.

Li S., Cullen W. K., Anwyl R. and Rowan M. J. (2007) Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 144, 754-761.

Wang Q., Chang L., Rowan M. J. and Anwyl R. (2007) Developmental dependence, the role of the kinases p38 MAPK and PKC, and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus. Neuroscience 144, 110-118.

Dr. Arun Bokde

Frodl T, Bokde AL, Scheuerecker J, Lisiecka D, Schoepf V, Hampel H, Moller HJ, Bruckmann H, Wiesmann M & Meisenzahl E (2009) Functional Connectivity Bias of the Orbitofrontal Cortex in Drug-Free Patients with Major Depression. Biol Psychiatry.

Bokde A.L., Ewers M. & Hampel H. (2009) Assessing neuronal networks: understanding Alzheimer's disease. Prog Neurobiol, 89, 125-33.

Bokde A.L., Karmann M., Teipel S.J., Born C., Lieb M., Reiser M.F., Moller H.J. & Hampel H. (2009) Decreased activation along the dorsal visual pathway after a 3-month treatment with galantamine in mild Alzheimer disease: a functional magnetic resonance imaging study. J Clin Psychopharmacol, 29, 147-56.

Hampel H., Burger K., Teipel S. J., Bokde A. L., Zetterberg H. and Blennow K. (2008) Core candidate neurochemical and imaging biomarkers of Alzheimer's disease. Alzheimers Dement 4, 38-48.

Teipel S. J., Born C., Ewers M., Bokde A. L., Reiser M. F., Moller H. J. and Hampel H. (2007) Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment. Neuroimage 38, 13-24.

Teipel S. J., Bokde A. L., Born C., Meindl T., Reiser M., Moller H. J. and Hampel H. (2007) Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study. Brain 130, 1745-1758.

Teipel S. J., Stahl R., Dietrich O., Schoenberg S. O., Perneczky R., Bokde A. L., Reiser M. F., Moller H. J. and Hampel H. (2007) Multivariate network analysis of fiber tract integrity in Alzheimer's disease. Neuroimage 34, 985-995.

Prof. Ruth Byrne

Byrne, R. M., and Johnson-Laird, P. N. (2009) 'If' and the problems of conditional reasoning, Trends Cogn Sci 13, 282-287.

McCloy R., Byrne R.M. & Johnson-Laird P.N. (2009) Understanding cumulative risk. Q J Exp Psychol (Colchester), 1-17.

Espino O., Santamaria C. & Byrne R.M. (2009) People think about what is true for conditionals, not what is false: only true possibilities prime the comprehension of "if". Q J Exp Psychol (Colchester), 62, 1072-8.

Byrne, R. M. J., Girotto, V.,Markman, K. & Klein. “Cognitive processes in counterfactual thinking” Handbook of the human imagination, Hove, Psychology Press.

Byrne, R. M. J. & Johnson-Laird, P. N. “Conditionals and Possibilities” in, editor(s)Oaksford, M. , Conditionals, Oxford, Oxford University Press.

Moreno-Rios, S., Garcia-Madruga, J. & Byrne, R. M. J. (2008) Semifactual “even if” reasoning, Acta Psychologica.

Byrne, R. M. J.(2007) Precis of The Rational Imagination: How People Create Alternatives to Reality (MIT Press). Behavioral and Brain Sciences, 30, p439 – 453.

Walsh, C. R. and Byrne, R. M. J., (2007) The effects of reasons for acting on counterfactual thinking., Thinking and Reasoning, 13, p461 – 483.

W. Schaeken, Vandierendonck, A., Schroyens, W., and d'Ydewalle, G. Byrne, R. M. J. (2007) The Mental Models Theory of Reasoning: Refinements and Extensions, Mahwah: New Jersey, Lawrence Erlbaum Associates, pp53 – 62.

Byrne, R. M. J. (2007)The rational imagination and other possibilities: Author's response, Behavioral and Brain Sciences, 30, p470 – 480.

McEleney A. and Byrne, R. M. J. (2006) Spontaneous causal and counterfactual thoughts. Thinking and Reasoning., 12, (2), 2006, p235 – 255.

Dr.Veronica Campbell

Gowran, A., Murphy, C. E., and Campbell, V. A. (2009) Delta(9)-tetrahydrocannabinol regulates the p53 post-translational modifiers Murine double minute 2 and the Small Ubiquitin MOdifier protein in the rat brain, FEBS Lett 583, 3412-3418.

Fogarty M. P., McCormack R. M., Noonan J., Murphy D., Gowran A. & Campbell V. A. (2008) A role for p53 in the beta-amyloid-mediated regulation of the lysosomal system. Neurobiol Aging.

Byrne E. M., Farrell E., McMahon L. A., Haugh M. G., O'Brien F. J., Campbell V. A., Prendergast P. J. and O'Connell B. C. (2008) Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation. J Mater Sci Mater Med.

McMahon L. A., Campbell V. A. and Prendergast P. J. (2008) Involvement of stretch-activated ion channels in strain-regulated glycosaminoglycan synthesis in mesenchymal stem cell-seeded 3D scaffolds. J Biomech 41, 2055-2059.

Gowran A. and Campbell V. A. (2008) A role for p53 in the regulation of lysosomal permeability by delta 9-tetrahydrocannabinol in rat cortical neurones: implications for neurodegeneration. J Neurochem 105, 1513-1524.

McMahon, L.A., Reid, A.J., Campbell, V.A., Prendergast, P.J.(2008) Regulatory effects of mechanical strain on the chondrogenic differentiation of MSCs in a collagen-GAG scaffold: experimental and computational analysis., Ann Biomed Eng, 36, p185 – 194.

Campbell, V. A., Downer, E. (2008) Cannabinoids and Neuroprotection in, editor(s)Attila Kofalvi , Cannabinoids and the Brain, Springer, pp317 – 330.

McMahon, L. A. , Prendergast, P. J. , Campbell, V. A.(2008) A comparison of the involvement of p38, ERK1/2 and PI3K in growth factor-induced chondrogenic differentiation of mesenchymal stem cells, Biochemical and Biophysical Research Communications , 368, (4), p990 – 995.

Kanichai, M., Ferguson, D., Prendergast, P. J., Campbell, V. A.(2008) Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia-inducible factor (HIF)-1, Journal of Cellular Physiology, online publication.

McMahon, L. A., Reid, A. J., Campbell, V.A., Prendergast, P. J. (2008) Regulatory effects of mechanical strain on the chondrogenic differentiation of MSCs in a collagen-GAG scaffold: experimental and computational analysis, Annals of Biomedical Engineering, 36, p185 – 194.

Campbell V. A. and Gowran A. (2007) Alzheimer's disease; taking the edge off with cannabinoids? Br J Pharmacol 152, 655-662.

Downer E. J., Gowran A. and Campbell V. A. (2007a) A comparison of the apoptotic effect of Delta(9)-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex. Brain Res 1175, 39-47.

Downer E. J., Gowran A., Murphy A. C. and Campbell V. A. (2007b) The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Delta9-tetrahydrocannabinol in cultured cortical neurons. Eur J Pharmacol 564, 57-65.

Farrell E., Byrne E. M., Fischer J., O'Brien F. J., O'Connell B. C., Prendergast P. J. and Campbell V. A. (2007) A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds. Technol Health Care 15, 19-31.

McGarry J. G., Maguire P., Campbell V. A., O'Connell B. C., Prendergast P. J. and Jarvis S. P. (2007) Stimulation of nitric oxide mechanotransduction in single osteoblasts using atomic force microscopy. J Orthop Res.

Dr.Thomas Connor

O'Sullivan, J. B., Ryan, K. M., Curtin, N. M., Harkin, A., and Connor, T. J. (2009) Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration, Int J Neuropsychopharmacol 12, 687-699.

McNamee, E. N., Ryan, K. M., Kilroy, D., and Connor, T. J. (2010) Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity, Eur J Pharmacol 626, 219-228.

Curtin N. M., Boyle N. T., Mills K. H. & Connor T. J. (2009) Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide. Brain Behav Immun, 23, 535-547.

Curtin N. M., Mills K. H. & Connor T. J. (2009) Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide. Brain Behav Immun, 23, 371-9.

O'Sullivan J. B., Ryan K. M., Curtin N. M., Harkin A. & Connor T. J. (2009) Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration. Int J Neuropsychopharmacol, 12, 687-99.

Connor T. J. (2008) Don't stress out your immune system - Just relax. Brain Behav Immun.

Connor T. J., Starr N., O'Sullivan J. B. and Harkin A. (2008) Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma? Neurosci Lett 441, 29-34.

Johnson K. A., Kelly S. P., Robertson I. H. Barry E., Mulligan A., Daly, M., Lambert D., McDonnell C., Connor T. J., Hawi Z., Gill M., Bellgrove M. A..(2008) Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

Boyle N. T. and Connor T. J. (2007) MDMA ("Ecstasy") suppresses the innate IFN-gamma response in vivo: a critical role for the anti-inflammatory cytokine IL-10. Eur J Pharmacol 572, 228-238.

Diamond M., Kelly J. P. and Connor T. J. (2006) Antidepressants suppress production of the Th1 cytokine interferon-gamma, independent of monoamine transporter blockade. Eur Neuropsychopharmacol 16, 481-490.

Horrigan L. A., Kelly J. P. and Connor T. J. (2006) Immunomodulatory effects of caffeine: friend or foe? Pharmacol Ther 111, 877-892.

Prof. Aiden Corvin

Merikangas, A. K., Corvin, A. P., and Gallagher, L. (2009) Copy-number variants in neurodevelopmental disorders: promises and challenges, Trends Genet 25, 536-544.

Donohoe, G., Frodl, T., Morris, D., Spoletini, I., Cannon, D. M., Cherubini, A., Caltagirone, C., Bossu, P., McDonald, C., Gill, M., Corvin, A. P., and Spalletta, G. (2010) Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia, Neuropsychopharmacology 35, 368-373.

Donohoe G., Hayden J., McGlade N., O'Grada C., Burke T., Barry S., Behan C., Dinan T. G., O'Callaghan E., Gill M. & Corvin A. P. (2009) Is "clinical" insight the same as "cognitive" insight in schizophrenia? J Int Neuropsychol Soc, 15, 471-5.

Donohoe G., Spoletini I., McGlade N., Behan C., Hayden J., O'Donoghue T., Peel R., Haq F., Walker C., O'Callaghan E., Spalletta G., Gill M. and Corvin A. (2009) Are relational style and neuropsychological performance predictors of social attributions in chronic schizophrenia? Psychiatry Res.

O'Grada C., Barry S., McGlade N., Behan C., Haq F., Hayden J., O'Donoghue T., Peel R., Morris D. W., O'Callaghan E., Gill M., Corvin A. P., Dinan T. G. and Donohoe G. (2009) Does the ability to sustain attention underlie symptom severity in schizophrenia? Schizophr Res.

Ferreira M. A., O'Donovan M. C., Meng Y. A., Jones I. R., Ruderfer D. M., Jones L., Fan J., Kirov G., Perlis R. H., Green E. K., Smoller J. W., Grozeva D., Stone J., Nikolov I., Chambert K., Hamshere M. L., Nimgaonkar V. L., Moskvina V., Thase M. E., Caesar S., Sachs G. S., Franklin J., Gordon-Smith K., Ardlie K. G., Gabriel S. B., Fraser C., Blumenstiel B., Defelice M., Breen G., Gill M., Morris D. W., Elkin A., Muir W. J., McGhee K. A., Williamson R., Macintyre D. J., Maclean A. W., St Clair D., Robinson M., Van Beck M., Pereira A. C., Kandaswamy R., McQuillin A., Collier D. A., Bass N. J., Young A. H., Lawrence J., Nicol Ferrier I., Anjorin A., Farmer A., Curtis D., Scolnick E. M., McGuffin P., Daly M. J., Corvin A. P., Holmans P. A., Blackwood D. H., Gurling H. M., Owen M. J., Purcell S. M., Sklar P. and Craddock N. (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet.

McGlade N., Behan C., Hayden J., O'Donoghue T., Peel R., Haq F., Gill M., Corvin A., O'Callaghan E. and Donohoe G. (2008) Mental state decoding v. mental state reasoning as a mediator between cognitive and social function in psychosis. Br J Psychiatry 193, 77-78.

O'Donovan M. C., Craddock N., Norton N., Williams H., Peirce T., Moskvina V., Nikolov I., Hamshere M., Carroll L., Georgieva L., Dwyer S., Holmans P., Marchini J. L., Spencer C. C., Howie B., Leung H. T., Hartmann A. M., Moller H. J., Morris D. W., Shi Y., Feng G., Hoffmann P., Propping P., Vasilescu C., Maier W., Rietschel M., Zammit S., Schumacher J., Quinn E. M., Schulze T. G., Williams N. M., Giegling I., Iwata N., Ikeda M., Darvasi A., Shifman S., He L., Duan J., Sanders A. R., Levinson D. F., Gejman P. V., Gejman P. V., Sanders A. R., Duan J., Levinson D. F., Buccola N. G., Mowry B. J., Freedman R., Amin F., Black D. W., Silverman J. M., Byerley W. F., Cloninger C. R., Cichon S., Nothen M. M., Gill M., Corvin A., Rujescu D., Kirov G. and Owen M. J. (2008) Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet.

Yang M. S., Morris D. W., Donohoe G., Kenny E., O'Dushalaine C. T., Schwaiger S., Nangle J. M., Clarke S., Scully P., Quinn J., Meagher D., Baldwin P., Crumlish N., O'Callaghan E., Waddington J. L., Gill M. and Corvin A. (2008) Chitinase-3-like 1 (CHI3L1) gene and schizophrenia: genetic association and a potential functional mechanism. Biol Psychiatry 64, 98-103.

Corvin A., Donohoe G., Nangle J. M., Schwaiger S., Morris D. and Gill M. (2008) A dysbindin risk haplotype associated with less severe manic-type symptoms in psychosis. Neurosci Lett 431, 146-149.

Donohoe G., Morris D. W., De Sanctis P., Magno E., Montesi J. L., Garavan H. P., Robertson I. H., Javitt D. C., Gill M., Corvin A. P. and Foxe J. J. (2008) Early visual processing deficits in dysbindin-associated schizophrenia. Biol Psychiatry 63, 484-489.

Donohoe G., Morris D. W., Clarke S., McGhee K. A., Schwaiger S., Nangle J. M., Garavan H., Robertson I. H., Gill M. and Corvin A. (2007) Variance in neurocognitive performance is associated with dysbindin-1 in schizophrenia: a preliminary study. Neuropsychologia 45, 454-458.

Donohoe G., Morris D. W., Robertson I. H., Clarke S., McGhee K. A., Schwaiger S., Nangle J. M., Gill M. and Corvin A. (2007) Variance in facial recognition performance associated with BDNF in schizophrenia. Am J Med Genet B Neuropsychiatr Genet 144, 578-579.

Barnett K. J., Finucane C., Asher J. E., Bargary G., Corvin A. P., Newell F. N. and Mitchell K. J. (2008) Familial patterns and the origins of individual differences in synaesthesia. Cognition 106, 871-893.

O'Dushlaine C. T., Dolan C., Weale M. E., Stanton A., Croke D. T., Kalviainen R., Eriksson K., Kantanen A. M., Gibson R. A., Hosford D., Sisodiya S. M., Gill M., Corvin A. P., Morris D. W., Delanty N. and Cavalleri G. L. (2008) An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy and other complex diseases. Eur J Hum Genet 16, 176-183.

Jones I., Hamshere M., Nangle J. M., Bennett P., Green E., Heron J., Segurado R., Lambert D., Holmans P., Corvin A., Owen M., Jones L., Gill M. and Craddock N. (2007) Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16. Am J Psychiatry 164, 1099-1104.

Morris D. W., Murphy K., Kenny N., Purcell S. M., McGhee K. A., Schwaiger S., Nangle J. M., Donohoe G., Clarke S., Scully P., Quinn J., Meagher D., Baldwin P., Crumlish N., O'Callaghan E., Waddington J. L., Gill M. and Corvin A. P. (2008) Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility. Biol Psychiatry 63, 24-31.

Waddington J. L., Corvin A. P., Donohoe G., O'Tuathaigh C. M., Mitchell K. J. and Gill M. (2007) Functional genomics and schizophrenia: endophenotypes and mutant models. Psychiatr Clin North Am 30, 365-399.

Corvin A., Donohoe G., McGhee K., Murphy K., Kenny N., Schwaiger S., Nangle J. M., Morris D. and Gill M. (2007) D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia. Neurosci Lett 426, 97-100.

Dr Colm Cunningham

Cunningham O., Campion S., Perry V. H., Murray C., Sidenius N., Docagne F. & Cunningham C. (2009) Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation. Glia.

Clive Holmes, Colm Cunningham, Elina Zotova, Jan Woolford, Christine Dean, Sara Kerr, David Culliford, and Hugh Perry (2009) Systemic inflammation and disease progression in Alzheimer’s disease Neurology 73(10):768-74.

Sanderson D. J., Cunningham C., Deacon R. M., Bannerman D. M., Perry V. H. & Rawlins J. N. (2009) A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning. Behav Brain Res, 201, 103-11.

Cunningham C., Campion S., Lunnon K., Murray C. L., Woods J. F., Deacon R. M., Rawlins J. N. & Perry V. H. (2009) Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease. Biol Psychiatry, 65, 304-12.

Maclullich A. M., Ferguson K. J., Miller T., de Rooij S. E. & Cunningham C. (2008) Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses. J Psychosom Res, 65, 229-38.

Asuni A. A., Cunningham C., Vigneswaran P., Perry V. H. & O'Connor V. (2008) Unaltered SNARE complex formation in an in vivo model of prion disease. Brain Res, 1233, 1-7.

Cunningham C. and Sanderson D. J. (2008) Malaise in the water maze: Untangling the effects of LPS and IL-1beta on learning and memory. Brain Behav Immun.

MacLullich, A., de Rooij, S., Miller, T., Ferguson, K., and Cunningham, C. (2008) Unravelling the pathophysiology of delirium: a focus on aberrant stress responses. Journal of Psychosomatic Research (In Press).

Palin, P., Cunningham, C., Forse, P.V., Perry, H. and Platt, N. (2008) Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration. Neurobiol. Dis.30, p.19-29.

Watkins, A.J., Wilkins, A., Cunningham, C., Perry, V.H., Seet, M.J., Osmond, C., Eckert, J.J., Torrens, C., Cagampang ,F.R., Cleal, J., Gray, W.P., Hanson, M.A., Fleming, T.P. (2008). Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring. J. Physiol; 586(8).p.2231-44.

Watkins A. J., Ursell E., Panton R., Papenbrock T., Hollis L., Cunningham C., Wilkins A., Perry V. H., Sheth B., Kwong W. Y., Eckert J. J., Wild A. E., Hanson M. A., Osmond C. and Fleming T. P. (2008) Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biol Reprod 78, 299-306.

Teeling, J.L., Felton, L.M., Deacon, R.M.J., Cunningham, C., Rawlins, J.N.P. and Perry, V.H. (2007) Subpyrogenic systemic inflammation impacts of brain and behaviour independent of cytokines. Brian, Behavior and Immunity, 21(6) 836-850.

Cunningham C., Campion S., Teeling J., Felton L. and Perry V. H. (2007) The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C). Brain Behav Immun 21, 490-502.

Perry V. H., Cunningham C. and Holmes C. (2007) Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immunol 7, 161-167.

Dr. Gavin Davey

Telford J. E., Kilbride S. M. & Davey G. P. (2009) Complex I is rate-limiting for oxygen consumption in the nerve terminal. J Biol Chem, 284, 9109-14.

Pathak R. U. and Davey G. P. (2008) Complex I and energy thresholds in the brain. Biochim Biophys Acta 1777, 777-782.

Kilbride S. M., Telford J. E. and Davey G. P. (2008) Age-related changes in H(2)O(2) production and bioenergetics in rat brain synaptosomes. Biochim Biophys Acta.

Kilbride S. M., Telford J. E., Tipton K. F. and Davey G. P. (2008) Partial inhibition of complex I activity increases Ca(2+)-independent glutamate release rates from depolarized synaptosomes. J Neurochem.

O'Sullivan J., Davey G., O'Sullivan M. and Tipton K. F. (2007) Hydrogen peroxide derived from amine oxidation mediates the interaction between aminosugars and semicarbazide-sensitive amine oxidase. J Neural Transm 114, 751-756.

Palmi M., Davey G., Tipton K. F. and Meini A. (2006) Taurine, taurine analogues, and mitochondrial function and dysfuntion. Adv Exp Med Biol 583, 469-479.

Dr. Paul Dockree

O'Connell RG, Dockree PM, Robertson IH, Bellgrove MA, Foxe JJ & Kelly SP (2009) Uncovering the neural signature of lapsing attention: electrophysiological signals predict errors up to 20 s before they occur. J Neurosci, 29, 8604-11.

O'Connell R. G., Bellgrove M. A., Dockree P. M., Lau A., Hester R., Garavan H., Fitzgerald M., Foxe J. J. & Robertson I. H. (2009) The neural correlates of deficient error awareness in attention-deficit hyperactivity disorder (ADHD). Neuropsychologia, 47, 1149-59.

O'Connell R. G., Dockree P. M., Bellgrove M. A., Turin A., Ward S., Foxe J. J. and Robertson I. H. (2008) Two Types of Action Error: Electrophysiological Evidence for Separable Inhibitory and Sustained Attention Neural Mechanisms Producing Error on Go/No-go Tasks. J Cogn Neurosci.

Hoerold D., Dockree P. M., O'Keeffe F. M., Bates H., Pertl M. and Robertson I. H. (2008) Neuropsychology of self-awareness in young adults. Exp Brain Res 186, 509-515.

O'Connell RG, Bellgrove MA, Dockree PM, Lau A, Fitzgerald M & Robertson IH (2008) Self-Alert Training: volitional modulation of autonomic arousal improves sustained attention. Neuropsychologia, 46, 1379-90.

O'Connell R. G., Dockree P. M., Bellgrove M. A., Kelly S. P., Hester R., Garavan H., Robertson I. H. and Foxe J. J. (2007) The role of cingulate cortex in the detection of errors with and without awareness: a high-density electrical mapping study. Eur J Neurosci 25, 2571-2579.

Dockree P. M., Kelly S. P., Foxe J. J., Reilly R. B. and Robertson I. H. (2007) Optimal sustained attention is linked to the spectral content of background EEG activity: greater ongoing tonic alpha (approximately 10 Hz) power supports successful phasic goal activation. Eur J Neurosci 25, 900-907.

O'Keeffe FM, Murray B, Coen RF, Dockree PM, Bellgrove MA, Garavan H, Lynch T & Robertson IH (2007) Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy. Brain, 130, 753-64.

O'Keeffe FM, Dockree PM, Moloney P, Carton S & Robertson IH (2007) Characterising error-awareness of attentional lapses and inhibitory control failures in patients with traumatic brain injury. Exp Brain Res, 180, 59-67.

O'Keeffe F, Dockree P, Moloney P, Carton S & Robertson IH (2007) Awareness of deficits in traumatic brain injury: a multidimensional approach to assessing metacognitive knowledge and online-awareness. J Int Neuropsychol Soc, 13, 38-49.

Dr. Jane Farrar

Campbell, M., Nguyen, A. T., Kiang, A. S., Tam, L. C., Gobbo, O. L., Kerskens, C., Ni Dhubhghaill, S., Humphries, M. M., Farrar, G. J., Kenna, P. F., and Humphries, P. (2009) An experimental platform for systemic drug delivery to the retina, Proc Natl Acad Sci U S A 106, 17817-17822.

Chadderton N., Millington-Ward S., Palfi A., O'Reilly M., Tuohy G., Humphries M. M., Li T., Humphries P., Kenna P. F. & Farrar G. J. (2009) Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy. Mol Ther, 17, 593-9.

Loscher C. J., Hokamp K., Wilson J. H., Li T., Humphries P., Farrar G. J. & Palfi A. (2008) A common microRNA signature in mouse models of retinal degeneration. Exp Eye Res, 87, 529-34.

Tam L. C., Kiang A. S., Kennan A., Kenna P. F., Chadderton N., Ader M., Palfi A., Aherne A., Ayuso C., Campbell M., Reynolds A., McKee A., Humphries M. M., Farrar G. J. and Humphries P. (2008) Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10). Hum Mol Genet 17, 2084-2100.

Reynolds A. L., Danciger M., Farrar G. J., Humphries P. and Kenna P. F. (2008) Influence of a quantitative trait locus on mouse chromosome 19 to the light-adapted electroretinogram. Invest Ophthalmol Vis Sci 49, 4058-4063.

Allen D., Winters E., Kenna P. F., Humphries P. and Farrar G. J. (2008) Reference gene selection for real-time rtPCR in human epidermal keratinocytes. J Dermatol Sci 49, 217-225.

Campbell M., Kiang A. S., Kenna P. F., Kerskens C., Blau C., O'Dwyer L., Tivnan A., Kelly J. A., Brankin B., Farrar G. J. and Humphries P. (2008) RNAi-mediated reversible opening of the blood-brain barrier. J Gene Med.

O'Reilly M., Millington-Ward S., Palfi A., Chadderton N., Cronin T., McNally N., Humphries M. M., Humphries P., Kenna P. F. and Farrar G. J. (2008) A transgenic mouse model for gene therapy of rhodopsin-linked Retinitis Pigmentosa. Vision Res 48, 386-391.

Reynolds A. L., Danciger M., Farrar G. J., Humphries P. and Kenna P. (2008) A quantitative trait locus on chromosome 19 controls variation in the murine light-adapted electroretinogram. Invest Ophthalmol Vis Sci.

Reynolds A. L., Farrar G. J., Humphries P. and Kenna P. F. (2008) Variation in the electroretinogram of C57BL/6 substrains of mouse. Adv Exp Med Biol 613, 383-391.

Allen D., Kenna P. F., Palfi A., McMahon H. P., Millington-Ward S., O'Reilly M., Humphries P. and Farrar G. J. (2007) Development of strategies for conditional RNA interference. J Gene Med 9, 287-298.

Loscher C. J., Hokamp K., Kenna P. F., Ivens A. C., Humphries P., Palfi A. and Farrar G. J. (2007) Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa. Genome Biol 8, R248.

O'Reilly M., Palfi A., Chadderton N., Millington-Ward S., Ader M., Cronin T., Tuohy T., Auricchio A., Hildinger M., Tivnan A., McNally N., Humphries M. M., Kiang A. S., Humphries P., Kenna P. F. and Farrar G. J. (2007) RNA interference-mediated suppression and replacement of human rhodopsin in vivo. Am J Hum Genet 81, 127-135.

Palfi A., Ader M., Kiang A. S., Millington-Ward S., Clark G., O'Reilly M., McMahon H. P., Kenna P. F., Humphries P. and Farrar G. J. (2006) RNAi-based suppression and replacement of rds-peripherin in retinal organotypic culture. Hum Mutat 27, 260-268.

Aherne A, Kennan A, Kenna PF, McNally N, Farrar GJ & Humphries P (2006) Molecular mechanisms of photoreceptor degeneration in RP caused by IMPDH1 mutations. Adv Exp Med Biol, 572, 81-7.

Prof. Thomas Frodl

Meisenzahl E. M., Seifert D., Bottlender R., Teipel S., Zetzsche T., Jager M., Koutsouleris N., Schmitt G., Scheuerecker J., Burgermeister B., Hampel H., Rupprecht T., Born C., Reiser M., Moller H. J. & Frodl T. (2009) Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. Eur Arch Psychiatry Clin Neurosci.

Frodl T. S., Koutsouleris N., Bottlender R., Born C., Jager M., Scupin I., Reiser M., Moller H. J. & Meisenzahl E. M. (2008) Depression-related variation in brain morphology over 3 years: effects of stress? Arch Gen Psychiatry, 65, 1156-65.

Frodl T., Jager M., Smajstrlova I., Born C., Bottlender R., Palladino T., Reiser M., Moller H. J. and Meisenzahl E. M. (2008) Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study. J Psychiatry Neurosci 33, 423-430.

Hennig-Fast K., Meister F., Frodl T., Beraldi A., Padberg F., Engel R. R., Reiser M., Moller H. J. and Meindl T. (2008) A case of persistent retrograde amnesia following a dissociative fugue: neuropsychological and neurofunctional underpinnings of loss of autobiographical memory and self-awareness. Neuropsychologia 46, 2993-3005.

Juckel G., Clotz F., Frodl T., Kawohl W., Hampel H., Pogarell O. and Hegerl U. (2008) Diagnostic usefulness of cognitive auditory event-related p300 subcomponents in patients with Alzheimers disease? J Clin Neurophysiol 25, 147-152.

Zetzsche T., Preuss U. W., Frodl T., Leinsinger G., Born C., Reiser M., Hegerl U., Moller H. J. and Meisenzahl E. M. (2008) White matter alterations in schizophrenic patients with pronounced negative symptomatology and with positive family history for schizophrenia. Eur Arch Psychiatry Clin Neurosci 258, 278-284.

Frodl T., Jager M., Born C., Ritter S., Kraft E., Zetzsche T., Bottlender R., Leinsinger G., Reiser M., Moller H. J. and Meisenzahl E. (2008) Anterior cingulate cortex does not differ between patients with major depression and healthy controls, but relatively large anterior cingulate cortex predicts a good clinical course. Psychiatry Res 163, 76-83.

Frodl T., Zill P., Baghai T., Schule C., Rupprecht R., Zetzsche T., Bondy B., Reiser M., Moller H. J. and Meisenzahl E. M. (2008) Reduced hippocampal volumes associated with the long variant of the tri- and diallelic serotonin transporter polymorphism in major depression. Am J Med Genet B Neuropsychiatr Genet 147B, 1003-1007.

Juckel G., Gudlowski Y., Muller D., Ozgurdal S., Brune M., Gallinat J., Frodl T., Witthaus H., Uhl I., Wutzler A., Pogarell O., Mulert C., Hegerl U. and Meisenzahl E. M. (2008) Loudness dependence of the auditory evoked N1/P2 component as an indicator of serotonergic dysfunction in patients with schizophrenia--a replication study. Psychiatry Res 158, 79-82.

Koutsouleris N., Gaser C., Jager M., Bottlender R., Frodl T., Holzinger S., Schmitt G. J., Zetzsche T., Burgermeister B., Scheuerecker J., Born C., Reiser M., Moller H. J. and Meisenzahl E. M. (2008) Structural correlates of psychopathological symptom dimensions in schizophrenia: a voxel-based morphometric study. Neuroimage 39, 1600-1612.

Frodl T., Scheuerecker J., Albrecht J., Kleemann A. M., Muller-Schunk S., Koutsouleris N., Moller H. J., Bruckmann H., Wiesmann M. and Meisenzahl E. (2007) Neuronal correlates of emotional processing in patients with major depression. World J Biol Psychiatry, 1-7.

Zetzsche T., Preuss U., Frodl T., Watz D., Schmitt G., Koutsouleris N., Born C., Reiser M., Moller H. J. and Meisenzahl E. M. (2007) In-vivo topography of structural alterations of the anterior cingulate in patients with schizophrenia: new findings and comparison with the literature. Schizophr Res 96, 34-45.
Mergl R., Pogarell O., Juckel G., Rihl J., Henkel V., Frodl T., Muller-Siecheneder F., Karner M., Tigges P., Schroter A. and Hegerl U. (2007) Hand-motor dysfunction in depression: characteristics and pharmacological effects. Clin EEG Neurosci 38, 82-88.

Frodl T., Schule C., Schmitt G., Born C., Baghai T., Zill P., Bottlender R., Rupprecht R., Bondy B., Reiser M., Moller H. J. and Meisenzahl E. M. (2007) Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Arch Gen Psychiatry 64, 410-416.

Zetzsche T., Preuss U. W., Frodl T., Schmitt G., Seifert D., Munchhausen E., Tabrizi S., Leinsinger G., Born C., Reiser M., Moller H. J. and Meisenzahl E. M. (2007) Hippocampal volume reduction and history of aggressive behaviour in patients with borderline personality disorder. Psychiatry Res 154, 157-170.

Prof. Hugh Garavan

Chambers, C. D., Garavan, H., and Bellgrove, M. A. (2009) Insights into the neural basis of response inhibition from cognitive and clinical neuroscience, Neurosci Biobehav Rev 33, 631-646.

Richardson, T. & Garavan, H. (2009). Self Reported Hypomanic and Psychotic Symptoms are Positively Correlated in an International Sample of Undergraduate Students. Asian Journal of Epidemiology, 2(3), 59-65.

Richardson, T. & Garavan, H. (2009). Hypomanic symptoms in female undergraduate students diagnosed with unipolar depression based on scores on the Hypomania Checklist. Clinical Practice and Epidemiology in Mental Health, 5, 22-5.

Braet, W., Johnson, K.A., Tobin, C.T., Acheson, R., Bellgrove, M.A., Robertson, I.H., & Garavan, H. (2009). Functional developmental changes underlying response inhibition and error-detection processes. NeuroPsychologia 47,
3143-3151

Magno, E., Simoes-Franklin, C., Robertson, I.H., & Garavan, H. (2009). The role of the dorsal anterior cingulate in evaluating behavior for achieving gains and avoiding losses. Journal of Cognitive Neuroscience 21, 2328-2342.

Hester, R., Nestor, L., & Garavan, H. (2009). Impaired error awareness and anterior cingulate cortex hypoactivity in chronic cannabis users.
Neuropsychopharmacology, 34(11), 2450-8.

Goldstein, R.Z., Craig, A.D., Bechara, A., Garavan, H., Childress, A.R., Paulus, M.P., & Volkow, N.D. (2009). The Neurocircuitry of Impaired Insight in Drug Addiction. Trends in Cognitive Sciences, 13, 372-380.

Chambers, C. D., Garavan, H., & Bellgrove, M.A. (2009). Insights into the neural basis of response inhibition from cognitive and clinical neuroscience.
Neuroscience and BioBehavioral Reviews, 33, 631-646.

Hester, R & Garavan, H. (2009). Neural mechanisms underlying drug-related cue distraction in active cocaine users. Pharmacology, Biochemistry and Behavior, 93, 270-277

Roberts, G.M.P., Nestor, L., & Garavan, H. (2009). Learning and memory deficits in ecstasy users and their neural correlates during a face-learning task. Brain Research 1292, 71-81.

O'Connell, R.G., Bellgrove, M.A., Dockree, P.M., Lau, A., Hester, R, Garavan, H.
Fitzgerald, M., Foxe, J.J., & Robertson, I.H. (2009). The Neural Correlates of Deficient Error Awareness in Attention-Deficit Hyperactivity Disorder (ADHD). Neuropsychologia 47, 1149-1159.

Fassbender, C., Murphy, K., Hester, R., Foxe, J. J., Foxe, D. M., Javitt, D. C., & Garavan, H. (2009). Prefrontal and midline interactions mediating behavioural control. European Journal of Neuroscience 29, 181-187.

Garavan, H, Kaufman, J.N., & Hester, R. (2008). Acute Effects of Cocaine on the Neurobiology of Cognitive Control. Philosophical Transactions of the Royal Society B Biol Sci., 363, 3267-76.

Roberts, G.M.P., Newell, F., Simões-Franklin, C. & Garavan, H. (2008).
Menstrual cycle phase modulates cognitive control over male but not female stimuli. Brain Research, 1224, 79-87. [Corrigendum 1251, 298].

Yeap, S., Kelly, S.P., Sehatpour, P., Magno, E., Garavan, H., Thakore, J.H., & Foxe, J.J. (2008). Visual sensory processing deficits in Schizophrenia and their relationship to disease state. European Archives of Psychiatry and Clinical Neuroscience 258, 305-316.

Magno, E., Yeap, S., Thakore, J.H., Garavan, H., De Sanctis, P., Javitt, D.C., & Foxe, J.J. (2008). Are Auditory-Evoked Frequency and Duration Mismatch Negativity (MMN) Deficits Endophenotypic for Schizophrenia? High-Density Electrical Mapping in Clinically Unaffected First-Degree Relatives, Recent-Onset and Chronic Schizophrenia. Biological Psychiatry 64, 385-391.

Donohoe, G., Morris, D.W., De Sanctis, P., Magno, E., Montesi, J.L., Garavan, H., Robertson, I.H., Javitt, D.C., Gill, M., Corvin, A.P., & Foxe, J.J. (2008).
Early Visual processing deficits in dysbindin-associated schizophrenia. Biological Psychiatry 63, 484-489.

Sanders, J, Johnson, K., Garavan, H., Gill, M., & Gallagher, L. (2008). A review of neuropsychological and neuroimaging research in autistic spectrum
disorders: Attention, inhibition and cognitive flexibility. Research in Autism Spectrum Disorders 2, 1-16.

Nestor, L., Roberts, G., Garavan, H., & Hester, R. (2008). Deficits in learning and memory: parahippocampal hyperactivity and frontocortical hypoactivity in cannabis users. NeuroImage 40, 1328-1339.

Chambers, C.D., Bellgrove, M.A., Gould, I.C., English, T., Garavan, H., McNaught, E., Kamke, M., & Mattingley, J.B. (2007). Dissociable mechanisms of cognitive control in human prefrontal cortex. Journal of Neurophysiology 98, 3638-47.

Landau, S. M., Garavan, H., Schumacher, E.H., & D'Esposito, M. (2007). Regional specificity and practice: Dynamic changes in object and spatial working memory. Brain Research 1180, 78-89.

Hester, R., Barre, N., Mattingley, J.B., Foxe, J.J., & Garavan, H. (2007).
Avoiding another mistake: Error and post-error neural activity associated with adaptive post-error response changes. Cognitive, Affective and Behavioral Neuroscience 7, 317-326.

Garavan, H., & Hester, R. (2007). The Role of Cognitive Control in Cocaine Dependence. Neuropsychology Review 17, 337-345.

Hester, R, Simões-Franklin, C., & Garavan, H. (2007). Post-error behaviour in active cocaine users: poor awareness of errors in the presence of intact performance adjustments. Neuropsychopharmacology 32 (9), 1974-1984

O'Connell, R.G., Dockree, P.M., Bellgrove, M.A., Kelly, S.P., Hester, R., Garavan, H., Robertson, I.H. & John J. Foxe (2007). The role of Cingulate Cortex in the detection of errors with and without awareness: A High-density electrical mapping and source-analysis study. European Journal of Neuroscience 25, 2571-2579.

O'Keeffe, F. , Murray, B., Coen, RF., Dockree, P., Bellgrove, M., Garavan, H., Lynch.T, & Robertson, I.H. (2007). Loss of Insight in Frontotemporal Dementia, Corticobasal Degeneration and Progressive Supranuclear Palsy. Brain 130,
753-764

Hester, R., D'Esposito, M., Cole, M. W. & Garavan, H. (2007). Neural mechanisms for response selection: comparing selection of items and responses from working memory. NeuroImage 34, 446-454.

Donohoe, G., Morris, D. W., Clarke, S., McGhee, K. A., Schwaiger, S., Nangle, J.-M., Garavan, H., Robertson, I. H., Gill, M., & Corvin, A. (2007). Variance In Neurocognitive Performance Is Associated With Dysbindin-1 In Schizophrenia:
A preliminary Study. Neuropsychologia 45, 454-8.

Prof. Michael Gill

McCarthy, S. E., Makarov, V., Kirov, G., Addington, A. M., McClellan, J., Yoon, S., Perkins, D. O., Dickel, D. E., Kusenda, M., Krastoshevsky, O., Krause, V., Kumar, R. A., Grozeva, D., Malhotra, D., Walsh, T., Zackai, E. H., Kaplan, P., Ganesh, J., Krantz, I. D., Spinner, N. B., Roccanova, P., Bhandari, A., Pavon, K., Lakshmi, B., Leotta, A., Kendall, J., Lee, Y. H., Vacic, V., Gary, S., Iakoucheva, L. M., Crow, T. J., Christian, S. L., Lieberman, J. A., Stroup, T. S., Lehtimaki, T., Puura, K., Haldeman-Englert, C., Pearl, J., Goodell, M., Willour, V. L., Derosse, P., Steele, J., Kassem, L., Wolff, J., Chitkara, N., McMahon, F. J., Malhotra, A. K., Potash, J. B., Schulze, T. G., Nothen, M. M., Cichon, S., Rietschel, M., Leibenluft, E., Kustanovich, V., Lajonchere, C. M., Sutcliffe, J. S., Skuse, D., Gill, M., Gallagher, L., Mendell, N. R., Craddock, N., Owen, M. J., O'Donovan, M. C., Shaikh, T. H., Susser, E., Delisi, L. E., Sullivan, P. F., Deutsch, C. K., Rapoport, J., Levy, D. L., King, M. C., and Sebat, J. (2009) Microduplications of 16p11.2 are associated with schizophrenia, Nat Genet 41, 1223-1227.

Bellgrove M.A., Johnson K.A., Barry E., Mulligan A., Hawi Z., Gill M., Robertson I. & Chambers C.D. (2009) Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry, 66, 1135-42.

Donohoe G., Walters J., Morris D.W., Quinn E.M., Judge R., Norton N., Giegling I., Hartmann A.M., Moller H.J., Muglia P., Williams H., Moskvina V., Peel R., O'Donoghue T., Owen M.J., O'Donovan M.C., Gill M., Rujescu D. & Corvin A. (2009) Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects. Arch Gen Psychiatry, 66, 1045-54.

Harold D., Abraham R., Hollingworth P., Sims R., Gerrish A., Hamshere M.L., Pahwa J.S., Moskvina V., Dowzell K., Williams A., Jones N., Thomas C., Stretton A., Morgan A.R., Lovestone S., Powell J., Proitsi P., Lupton M.K., Brayne C., Rubinsztein D.C., Gill M., Lawlor B., Lynch A., Morgan K., Brown K.S., Passmore P.A., Craig D., McGuinness B., Todd S., Holmes C., Mann D., Smith A.D., Love S., Kehoe P.G., Hardy J., Mead S., Fox N., Rossor M., Collinge J., Maier W., Jessen F., Schurmann B., van den Bussche H., Heuser I., Kornhuber J., Wiltfang J., Dichgans M., Frolich L., Hampel H., Hull M., Rujescu D., Goate A.M., Kauwe J.S., Cruchaga C., Nowotny P., Morris J.C., Mayo K., Sleegers K., Bettens K., Engelborghs S., De Deyn P.P., Van Broeckhoven C., Livingston G., Bass N.J., Gurling H., McQuillin A., Gwilliam R., Deloukas P., Al-Chalabi A., Shaw C.E., Tsolaki M., Singleton A.B., Guerreiro R., Muhleisen T.W., Nothen M.M., Moebus S., Jockel K.H., Klopp N., Wichmann H.E., Carrasquillo M.M., Pankratz V.S., Younkin S.G., Holmans P.A., O'Donovan M., Owen M.J. & Williams J. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet, 41, 1088-93.

Andreychik M.R. & Gill M.J. (2009) Ingroup Identity Moderates the Impact of Social Explanations on Intergroup Attitudes: External Explanations Are Not Inherently Prosocial. Pers Soc Psychol Bull.

Hamshere M.L., Schulze T.G., Schumacher J., Corvin A., Owen M.J., Jamra R.A., Propping P., Maier W., Orozco y Diaz G., Mayoral F., Rivas F., Jones I., Jones L., Kirov G., Gill M., Holmans P.A., Nothen M.M., Cichon S., Rietschel M. & Craddock N. (2009) Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31. Bipolar Disord, 11, 610-20.

O'Dushlaine C., Kenny E., Heron E.A., Segurado R., Gill M., Morris D.W. & Corvin A. (2009) The SNP ratio test: pathway analysis of genome-wide association datasets. Bioinformatics, 25, 2762-3.

Doyle C., Brookes K., Simpson J., Park J., Scott S., Coghill D.R., Hawi Z., Kirley A., Gill M. & Kent L. (2009) Replication of an association of a promoter polymorphism of the dopamine transporter gene and Attention Deficit Hyperactivity Disorder. Neurosci Lett, 462, 179-81.

Lupton M. K., Stahl D., Archer N., Foy C., Poppe M., Lovestone S., Hollingworth P., Williams J., Owen M. J., Dowzell K., Abraham R., Sims R., Brayne C., Rubinsztein D., Gill M., Lawlor B., Lynch A. & Powell J. F. (2009) Education, occupation and retirement age effects on the age of onset of Alzheimer's disease. Int J Geriatr Psychiatry.

Marco R., Miranda A., Schlotz W., Melia A., Mulligan A., Muller U., Andreou P., Butler L., Christiansen H., Gabriels I., Medad S., Albrecht B., Uebel H., Asherson P., Banaschewski T., Gill M., Kuntsi J., Mulas F., Oades R., Roeyers H., Steinhausen H. C., Rothenberger A., Faraone S. V. & Sonuga-Barke E. J. (2009) Delay and reward choice in ADHD: An experimental test of the role of delay aversion. Neuropsychology, 23, 367-80.

Correia C., Coutinho A. M., Almeida J., Lontro R., Lobo C., Miguel T.S., Martins M., Gallagher L., Conroy J., Gill M., Oliveira G. & Vicente A. M. (2009) Association of the alpha4 integrin subunit gene (ITGA4) with autism. Am J Med Genet B Neuropsychiatr Genet.

Johnson K. A., Robertson I. H., Barry E., Mulligan A., Daibhis A., Daly M., Watchorn A., Gill M. & Bellgrove M. A. (2008) Impaired conflict resolution and alerting in children with ADHD: evidence from the Attention Network Task (ANT). J Child Psychol Psychiatry, 49, 1339-47.

Altink M. E., Arias-Vasquez A., Franke B., Slaats-Willemse D. I., Buschgens C. J., Rommelse N. N., Fliers E. A., Anney R., Brookes K. J., Chen W., Gill M., Mulligan A., Sonuga-Barke E., Thompson M., Sergeant J. A., Faraone S. V., Asherson P. & Buitelaar J. K. (2008) The dopamine receptor D4 7-repeat allele and prenatal smoking in ADHD-affected children and their unaffected siblings: no gene-environment interaction. J Child Psychol Psychiatry, 49, 1053-60.

Zhou K. Dempfle A., Arcos-Burgos M., Bakker S. C., Banaschewski T., Biederman J., Buitelaar J., Castellanos F. X., Doyle A., Ebstein R. P., Ekholm J., Forabosco P., Franke B., Freitag C., Friedel S., Gill M., Hebebrand J., Hinney A., Jacob C., Lesch K. P., Loo S. K., Lopera F., McCracken J. T., McGough J. J., Meyer J., Mick E., Miranda A., Muenke M., Mulas F., Nelson S. F., Nguyen T. T., Oades R. D., Ogdie M. N., Palacio J. D., Pineda D., Reif A., Renner T. J., Roeyers H., Romanos M., Rothenberger A., Schafer H., Sergeant J., Sinke R. J., Smalley S. L., Sonuga-Barke E., Steinhausen H. C., van der Meulen E., Walitza S., Warnke A., Lewis C. M., Faraone S. V. & Asherson P. (2008) Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, 147B, 1392-8.

Neale B. M., Lasky-Su J., Anney R., Franke B., Zhou K., Maller J. B., Vasquez A. A., Asherson P., Chen W., Banaschewski T., Buitelaar J., Ebstein R., Gill M., Miranda A., Oades R. D., Roeyers H., Rothenberger A., Sergeant J., Steinhausen H. C., Sonuga-Barke E., Mulas F., Taylor E., Laird N., Lange C., Daly M. & Faraone S. V. (2008) Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, 147B, 1337-44.

Greene C. M., Bellgrove M. A., Gill M. & Robertson I. H. (2009) Noradrenergic genotype predicts lapses in sustained attention. Neuropsychologia, 47, 591-4.

Anney R. J., Lasky-Su J., O'Dushlaine C., Kenny E., Neale B. M., Mulligan A., Franke B., Zhou K., Chen W., Christiansen H., Arias-Vasquez A., Banaschewski T., Buitelaar J., Ebstein R., Miranda A., Mulas F., Oades R. D., Roeyers H., Rothenberger A., Sergeant J., Sonuga-Barke E., Steinhausen H., Asherson P., Faraone S. V. & Gill M. (2008) Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Am J Med Genet B Neuropsychiatr Genet, 147B, 1369-78.

Lasky-Su J., Anney R. J., Neale B. M., Franke B., Zhou K., Maller J. B., Vasquez A. A., Chen W., Asherson P., Buitelaar J., Banaschewski T., Ebstein R., Gill M., Miranda A., Mulas F., Oades R. D., Roeyers H., Rothenberger A., Sergeant J., Sonuga-Barke E., Steinhausen H. C., Taylor E., Daly M., Laird N., Lange C. & Faraone S. V.(2008) Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, 147B, 1355-8.

Sonuga-Barke E. J., Lasky-Su J., Neale B. M., Oades R., Chen W., Franke B., Buitelaar J., Banaschewski T., Ebstein R., Gill M., Anney R., Miranda A., Mulas F., Roeyers H., Rothenberger A., Sergeant J., Steinhausen H. C., Thompson M., Asherson P. & Faraone S. V. (2008) Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan. Am J Med Genet B Neuropsychiatr Genet, 147B, 1359-68.

Conroy J., Cochrane L., Anney R. J., Sutcliffe J. S., Carthy P., Dunlop A., Mullarkey M., O'Hici B., Green A. J., Ennis S., Gill M. & Gallagher L. (2009) Fine mapping and association studies in a candidate region for autism on chromosome 2q31-q32. Am J Med Genet B Neuropsychiatr Genet, 150B, 535-44.

Lasky-Su J., Neale B. M., Franke B., Anney R. J., Zhou K., Maller J. B., Vasquez A. A., Chen W., Asherson P., Buitelaar J., Banaschewski T., Ebstein R., Gill M., Miranda A., Mulas F., Oades R. D., Roeyers H., Rothenberger A., Sergeant J., Sonuga-Barke E., Steinhausen H. C., Taylor E., Daly M., Laird N., Lange C. & Faraone S. V. (2008) Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet, 147B, 1345-54.
Donohoe G., Spoletini I., McGlade N., Behan C., Hayden J., O'Donoghue T., Peel R., Haq F., Walker C., O'Callaghan E., Spalletta G., Gill M. & Corvin A. (2008) Are relational style and neuropsychological performance predictors of social attributions in chronic schizophrenia? Psychiatry Res, 161, 19-27.

Mefford H. C., Sharp A. J., Baker C., Itsara A., Jiang Z., Buysse K., Huang S., Maloney V. K., Crolla J. A., Baralle D., Collins A., Mercer C., Norga K., de Ravel T., Devriendt K., Bongers E. M., de Leeuw N., Reardon W., Gimelli S., Bena F., Hennekam R. C,. Male A., Gaunt L., Clayton-Smith J., Simonic I., Park S.M., Mehta S. G., Nik-Zainal S., Woods C. G., Firth H. V., Parkin G., Fichera M., Reitano S., Lo Giudice M., Li K. E., Casuga I., Broomer A., Conrad B., Schwerzmann M., Raber L., Gallati S., Striano P., Coppola A., Tolmie J. L., Tobias E. S., Lilley C., Armengol L., Spysschaert Y., Verloo P., De Coene A., Goossens L., Mortier G., Speleman F., van Binsbergen E., Nelen M. R., Hochstenbach R., Poot M., Gallagher L., Gill M., McClellan J., King M.C., Regan R., Skinner C., Stevenson R. E., Antonarakis S. E., Chen C., Estivill X., Menten B., Gimelli G., Gribble S., Schwartz S., Sutcliffe J. S., Walsh T., Knight S. J., Sebat J., Romano C., Schwartz C. E., Veltman J. A., de Vries B. B., Vermeesch J. R., Barber J. C., Willatt L., Tassabehji M. & Eichler E. E. (2008) Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes. N Engl J Med, 359, 1685-99.

O'Grada C., Barry S., McGlade N., Behan C., Haq F., Hayden J., O'Donoghue T., Peel R., Morris D. W., O'Callaghan E., Gill M., Corvin A. P., Dinan T. G. & Donohoe G. (2009) Does the ability to sustain attention underlie symptom severity in schizophrenia? Schizophr Res, 107, 319-23.

Ferreira M. A., O'Donovan M. C., Meng Y. A., Jones I. R., Ruderfer D. M., Jones L., Fan J., Kirov G., Perlis R. H., Green E. K., Smoller J. W., Grozeva D., Stone J., Nikolov I., Chambert K., Hamshere M. L., Nimgaonkar V. L., Moskvina V., Thase M. E., Caesar S., Sachs G. S., Franklin J., Gordon-Smith K., Ardlie K. G., Gabriel S. B., Fraser C., Blumenstiel B., Defelice M., Breen G., Gill M., Morris D. W., Elkin A., Muir W. J., McGhee K. A., Williamson R., MacIntyre D. J., MacLean A. W., St C. D., Robinson M., Van Beck M., Pereira A. C., Kandaswamy R., McQuillin A., Collier D. A., Bass N. J., Young A. H., Lawrence J., Ferrier I. N., Anjorin A., Farmer A., Curtis D., Scolnick E. M., McGuffin P., Daly M. J., Corvin A. P., Holmans P. A., Blackwood D. H., Gurling H. M., Owen M. J., Purcell S. M., Sklar P. & Craddock N. (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet, 40, 1056-8.

McGlade N., Behan C., Hayden J., O'Donoghue T., Peel R., Haq F., Gill M., Corvin A., O'Callaghan E. & Donohoe G. (2008) Mental state decoding v. mental state reasoning as a mediator between cognitive and social function in psychosis. Br J Psychiatry, 193, 77-8.

O'Donovan M. C., Craddock N., Norton N., Williams H., Peirce T., Moskvina V., Nikolov I., Hamshere M., Carroll L., Georgieva L., Dwyer S., Holmans P., Marchini J. L., Spencer C. C., Howie B., Leung H. T., Hartmann A. M., Moller H. J., Morris D. W., Shi Y., Feng G., Hoffmann P., Propping P., Vasilescu C., Maier W., Rietschel M., Zammit S., Schumacher J., Quinn E. M., Schulze T. G., Williams N. M., Giegling I., Iwata N., Ikeda M., Darvasi A., Shifman S., He L., Duan J., Sanders A. R., Levinson D. F., Gejman P. V., Cichon S., Nothen M. M., Gill M., Corvin A., Rujescu D., Kirov G., Owen M. J., Buccola N. G., Mowry B. J., Freedman R., Amin F., Black D. W., Silverman J. M., Byerley W. F. & Cloninger C. R. (2008) Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet, 40, 1053-5.

Anney R. J., Kenny E., O'Dushlaine C. T., Lasky-Su J., Franke B., Morris D. W., Neale B. M., Asherson P., Faraone S. V. & Gill M. (2008) Non-random error in genotype calling procedures: implications for family-based and case-control genome-wide association studies. Am J Med Genet B Neuropsychiatr Genet, 147B, 1379-86.

Mulligan A., Anney R. J., O'Regan M., Chen W., Butler L., Fitzgerald M., Buitelaar J., Steinhausen H. C., Rothenberger A., Minderaa R., Nijmeijer J., Hoekstra P. J., Oades R. D., Roeyers H., Buschgens C., Christiansen H., Franke B., Gabriels I., Hartman C., Kuntsi J., Marco R., Meidad S., Mueller U., Psychogiou L., Rommelse N., Thompson M., Uebel H., Banaschewski T., Ebstein R., Eisenberg J., Manor I., Miranda A., Mulas F., Sergeant J., Sonuga-Barke E., Asherson P., Faraone S. V. and Gill M. (2008) Autism symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders. J Autism Dev Disord.

Khan, A., Kelly, R., Gill, M.. (2008) Survey of symptoms associated with antidepressant discontinuation., Psychological Medicine, 16, (3), p89 – 92.

Donohoe, G., Morris, D. W., De Sanctis, P., Magno, E., Montesi, J., Garavan, H., Robertson, I., Javitt, D., Gill, M., Corvin, A., Fox, J.. (2008) Early Visual Processing Deficits in Dysbindin-Associated Schizophrenia, Biological Psychiatry, 63, (5), p484 – 489.

Asherson, P., Zhou, K., Anney, R. J., Franke, B., Buitelaar, J., Ebstein, R., Gill, M., Altink, M., Arnold, R., Boer, F., Brookes, K., Buschgens, C., Butler, L., Cambell, D., Chen, W., Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Johansson, L., Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Neale, B., Rijsdijk, F., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Xu, X., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Manor, I., Miranda, A., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H. C., Taylor, E., Thompson, M., Faraone, S. V..(2008) A High Density SNP Linkage Scan with 142 combined subtype ADHD Sib Pairs Identifies Replicated Linkage Regions on chromosomes 9 and 16., Mol Psychiatry, Epub ahead of print, p1 – 8.

Morris, D. W., Murphy, K., Kenny, N., Purcell, S. M., McGhee, K. A., Schwaiger, S., Nangle, J. M., Donohoe, G., Clarke, S., Scully, P., Quinn, J., Meagher, D., Baldwin, P., Crumlish, N., O’Callaghan, E., Waddington, J.L., Gill, M., Corvin, A.P.. (2008) Dysbindin (DTNBP1) and the BLOC-1 protein complex: main and epistatic gene effects are potential contributors to schizophrenia susceptibility, Biological Psychiatry, 63, (1), p24 – 31.

Johnson, K.A., Barry, E., Bellgrove, M.A., Cox, M., Kelly, S.P., Daibhis, A., Daly, M., Keavey, M., Watchorn, M., Fitzgerald, M., McNicholas, F., Kirley, A., Robertson, I.H., Gill, M.. (2008) Dissociation in response to methylphenidate on response variability in a group of medication naïve children with ADHD , Neuropsychologia, 46, (5), p1532 – 1541.

Sanders, J., Johnson, K., Garavan, H., Gill, M., Gallagher, L.. (2008) A review of neuropsychological and neuroimaging research in autistic spectrum disorders: Attention, inhibition and cognitive flexibility., Research in Autism Spectrum Disorders, 2, (1), p1 – 16.

Yang, M. S., Morris, D. W., Kenny, E., O’Dushalaine, C. T., Schwaiger, S., Nangle, J. M., Clarke, S., Scully, P., Quinn, J., Meagher, D., Baldwin, P., Crumlish, N., O’Callaghan, E., Waddington, J. L., Gill, M., Corvin, A.. (2008) Chitinase-3-Like1 (CHI3L1) Gene and Schizophrenia: Genetic Association and a Potential functional Mechanism. , Biological Psychiatry.

Corvin, A., Donohoe, G., Nangle, J. M., Schwaiger, S., Morris, D., Gill, M.. (2008) A dysbindin risk haplotype associated with less severe manic-type symptoms in psychosis., Neuroscience Letters, 431, (2), p146 – 149.

O'Dushlaine, C. T., Dolan, C., Weale, M. E., Stanton, A., Croke, D. T., Kalviainen, R., Eriksson, K., Kantanen, A. M., Gibson, R. A., Hosford, D., Sisodiya, S. M., Gill, M., Corvin, A. P., Morris, D. W., Delanty, N., Cavalleri, G.L.. (2008) An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy and other complex diseases, Eur J Hum Genet, 16, (2), p176 - 183

Sanders, J., Gill, M.. (2007) Unravelling the genome - A review of molecular gentic research in schizophrenia, Irish Journal of Medical Science , 176, (1), p5 – 9.

Jones, I., Hanshere, M.L., Nangle, J.M., Bennett, P., Middle, F., Heron, J., Segurado, R., Lambert, D., Williams, H., Corvin, A., Owen, J.J., Jones, L., Gill, M., Craddock, N.. (2007) Bipolar affective puerperal psychosis- genome-wide significant evidence for linkage to chromosome 16., American Journal of Psychiatry , 164, (7), p1 – 6.

Thapar, A., Langley, K., Asherson, P., Gill, M.. (2007) Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a develomental perspective, British Journal of Psychiatry, 190, p1 – 3.

Lasky-Su, J., Banaschewski, T., Buitelaar, J., Branke, B., Brookes, K., Sonuga-Barke, E., Ebstein, R., Eisenberg, J., Gill, M., Manor, I., Miranda, A., Mulas, F., Oades, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H,, Taylor, E., Zhou, K., Thompson, M., Asherson, P., Faraone, S.. (2007) Partial Replication of a DRD4 association in ADHD individuals using a statistically derived quantitative trait for ADHD in a family-based association test. , Biological Psychaitry, 62, (9), p985 – 990.

Bellgrove, M.A., Chambers, C.D., Johnson, K.A., Dáibhis, A., Daly, M., Hawi, Z., Lambert, D., Gill, M., Robertson, I.H.. (2007) Dopaminergic genotype biases spatial attention in healthy children, Molecular Psychiatry, 12, (8), p786 – 792.

Johnson, K., Robertson, I., Kelly, S., Silk, T., Barry, E., Daibhis, A., Watchorn, A., Keavey, M., Fitzgerald, M., Gallagher, L., Gill, M., Bellgrove, M.. (2007) Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention. Neuropsychologia, 45, p2234 – 2245.

Johnson, K.A., Kelly, S.P., Belgrove, M.A., Barry, E., Cox, M., Gill, M., Robertson, I.H.. (2007) Response variability in attention deficit hyperactivity disorder: evidence for neuropsychological heterogeneity., Neuropsychologia, 45, (4), p630 – 638.

Fitzmaurice, B., Armstrong, K., Carroll, V., Dagger, D., Gill, M.. (2007) Virtual Interviews for Students Interaction Online for Psychiatry (VISIOn): a novel resource for learning clinical interview skills., Psychiatric Bulletin, 31, p218 – 220.

Moskvina, V., Farmer, A., Jones, I., Brewster, S., Ferrero, F., Gill, M., Jones, L., Maier, W., Mors, O., Owen, M., Perry, J., Preisig, M., Rietschel, M., McGuffin, P., Craddock, N., Korszun, A.. (2007) Sex Differences in Symptom Patterns of Recurrent Major Depression in Siblings. Depress Anxiety, Oct 12.

Johnson, K., Robertson, I., Barry, E., Mulligan, A., Gill, M., Bellgrove, M.. (2007) Impaired conflict resolution and alerting in children with ADHD: Evidence from the Attention Network Task (ANT), Biological Psychiatry.

Waddington, J. L., Corvin, A., Donohoe, G., O’Tuathaigh, C., Mitchell, K., Gill, M.. (2007) Functional genomics and schizophrenia; endophenotypes and mutant models., Psychaitr Clin North Am., 30, p365 – 399.

Donohoe, G., Morris, D.W., Robertson, I. H., McGhee, K. A., Murphy, K., Kenny, N., Clarke, S., Gill, M., Corvin, A. P.. (2007) DAOA ARG30LYS and verbal memory function in schizophrenia., Molecular Psychiatry, 12, (9), p795 – 796.

Corvin, A., Donohoe, G., McGhee, K., Murphy, K., Kenny, N., Schwaiger, S., Nangle, J. M., Morris, D., Gill, M.. (2007) D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia., Neuroscience Letters, 426, (2), p97 – 100.

Grupe, A., Abraham, R., Li, Y., Rowland, C., Hollingworth, P., Morgan, A., Jehu, L., Segurado, R., Stone, D., Schadt. E., Karnoub, M., Nowotny, P., Tacey, K., Catanese, J., Sninsky, J., Brayne, C., Rubinsztein, D., Gill, M., Lawlor, B., Lovestone, S., Holmans, P., O'Donovan, M., Morris, J. C., Thal, L., Goate, A., Owen, M.J., Williams, J.. (2007) Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants., Human Molecular Genetics, 16, (8), p865 – 873.

Corvin, A., McGhee, K. A., Murphy, K., Donohoe, G., Nangle, J. M., Schwaiger, S., Kenny, N., Clarke, S., Meagher, D., Quinn, J., Scully, P., Baldwin, P., Browne, D., Walsh, C., Waddington, J. L., Morris, D. W., Gill, M.. (2007) Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 144, (7), p949 – 953

Bellgrove M. A., Chambers C. D., Johnson K. A., Daibhis A., Daly M., Hawi Z., Lambert D., Gill M. and Robertson I. H. (2007) Dopaminergic genotype biases spatial attention in healthy children. Mol Psychiatry.

Grupe A., Abraham R., Li Y., Rowland C., Hollingworth P., Morgan A., Jehu L., Segurado R., Stone D., Schadt E., Karnoub M., Nowotny P., Tacey K., Catanese J., Sninsky J., Brayne C., Rubinsztein D., Gill M., Lawlor B., Lovestone S., Holmans P., O'Donovan M., Morris J. C., Thal L., Goate A., Owen M. J. and Williams J. (2007) Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet 16, 865-873.

Johnson K. A., Kelly S. P., Bellgrove M. A., Barry E., Cox M., Gill M. and Robertson I. H. (2007) Response variability in attention deficit hyperactivity disorder: evidence for neuropsychological heterogeneity. Neuropsychologia 45, 630-638.

Johnson K. A., Robertson I. H., Kelly S. P., Silk T. J., Barry E., Daibhis A., Watchorn A., Keavey M., Fitzgerald M., Gallagher L., Gill M. and Bellgrove M. A. (2007) Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention. Neuropsychologia 45, 2234-2245.

Morgan A. R., Turic D., Jehu L., Hamilton G., Hollingworth P., Moskvina V., Jones L., Lovestone S., Brayne C., Rubinsztein D. C., Lawlor B., Gill M., O'Donovan M C., Owen M. J. and Williams J. (2007) Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet.

Sheehan K., Hawi Z., Gill M. and Kent L. (2007) No association between TPH2 gene polymorphisms and ADHD in a UK sample. Neurosci Lett 412, 105-107.

Yang M. S. and Gill M. (2007) A review of gene linkage, association and expression studies in autism and an assessment of convergent evidence. Int J Dev Neurosci 25, 69-85.

Yang M. S., Cochrane L., Conroy J., Hawi Z., Fitzgerald M., Gallagher L. and Gill M. (2007) Protein kinase C-beta 1 gene variants are not associated with autism in the Irish population. Psychiatr Genet 17, 39-41.

Prof. Harald Hampel

Schneider, P., Hampel, H., and Buerger, K. (2009) Biological marker candidates of Alzheimer's disease in blood, plasma, and serum, CNS Neurosci Ther 15, 358-374.

Hampel, H., Shen, Y., Walsh, D. M., Aisen, P., Shaw, L. M., Zetterberg, H., Trojanowski, J. Q., and Blennow, K. (2009) Biological markers of amyloid beta-related mechanisms in Alzheimer's disease, Exp Neurol.

Teipel S. J., Meindl T., Wagner M., Kohl T., Burger K., Reiser M. F., Herpertz S., Moller H. J. & Hampel H. (2009) White Matter Microstructure in Relation to Education in Aging and Alzheimer's Disease. J Alzheimers Dis.

Buerger K., Ernst A., Ewers M., Uspenskaya O., Omerovic M., Morgenthaler N. G., Knauer K., Bergmann A. & Hampel H. (2009) Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio. Biol Psychiatry, 65, 979-84.

Kornhuber J., Schmidtke K., Frolich L., Perneczky R., Wolf S., Hampel H., Jessen F., Heuser I., Peters O., Weih M., Jahn H., Luckhaus C., Hull M., Gertz H. J., Schroder J., Pantel J., Rienhoff O., Seuchter S. A., Ruther E., Henn F., Maier W. & Wiltfang J. (2009) Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network. Dement Geriatr Cogn Disord, 27, 404-17.

Carrillo M. C., Blackwell A., Hampel H., Lindborg J., Sperling R., Schenk D., Sevigny J. J., Ferris S., Bennett D. A., Craft S., Hsu T. & Klunk W. (2009) Early risk assessment for Alzheimer's disease. Alzheimers Dement, 5, 182-96.

Wei X., Du Z., Zhao L., Feng D., Wei G., He Y., Tan J., Lee W.H., Hampel H., Dodel R., Johnstone B.H., March K.L., Farlow M.R. & Du Y. (2009) IFATS collection: The conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats. Stem Cells, 27, 478-88.

Teipel S. J., Pogarell O., Meindl T., Dietrich O., Sydykova D., Hunklinger U., Georgii B., Mulert C., Reiser M. F., Moller H. J. and Hampel H. (2008) Regional networks underlying interhemispheric connectivity: An EEG and DTI study in healthy ageing and amnestic mild cognitive impairment. Hum Brain Mapp.

Bokde A. L., Lopez-Bayo P., Born C., Dong W., Meindl T., Leinsinger G., Teipel S. J., Faltraco F., Reiser M., Moller H. J. and Hampel H. (2008) Functional abnormalities of the visual processing system in subjects with mild cognitive impairment: An fMRI study. Psychiatry Res 163, 248-259.

Frisoni G. B., Henneman W. J., Weiner M. W., Scheltens P., Vellas B., Reynish E., Hudecova J., Hampel H., Burger K., Blennow K., Waldemar G., Johannsen P., Wahlund L. O., Zito G., Rossini P. M., Winblad B. and Barkhof F. (2008) The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium. Alzheimers Dement 4, 255-264.

Hampel H., Burger K., Teipel S. J., Bokde A. L., Zetterberg H. and Blennow K. (2008) Core candidate neurochemical and imaging biomarkers of Alzheimer's disease. Alzheimers Dement 4, 38-48.

Hampel H. and Shen Y. (2008) Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease. Scand J Clin Lab Invest, 1-5.

Clendenning M., Senter L., Hampel H., Lagerstedt Robinson K., Sun S., Buchanan D., Walsh M. D., Nilbert M., Green J. S., Potter J., Lindblom A. and de la Chapelle A. (2008) A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome. J Med Genet.

Clendenning M., Baze M. E., Sun S., Walsh K., Liyanarachchi S., Fix D., Schunemann V., Comeras I., Deacon M., Lynch J. F., Gong G., Thomas B. C., Thibodeau S. N., Lynch H. T., Hampel H. and de la Chapelle A. (2008) Origins and prevalence of the American Founder Mutation of MSH2. Cancer Res 68, 2145-2153.

Cohn D. E., Pavelka J. C., Frankel W. L., Morrison C. D., Hampel H., Copeland L. J. and Fowler J. M. (2008) Correlation between patient weight and defects in DNA mismatch repair: is this the link between an increased risk of previous cancer in thinner women with endometrial cancer? Int J Gynecol Cancer 18, 136-140.

Ewers M., Zhong Z., Burger K., Wallin A., Blennow K., Teipel S. J., Shen Y. and Hampel H. (2008) Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease. Brain 131, 1252-1258.

Juckel G., Clotz F., Frodl T., Kawohl W., Hampel H., Pogarell O. and Hegerl U. (2008) Diagnostic Usefulness of Cognitive Auditory Event-Related P300 Subcomponents in Patients With Alzheimers Disease? J Clin Neurophysiol.

Lerch J. P., Pruessner J., Zijdenbos A. P., Collins D. L., Teipel S. J., Hampel H. and Evans A. C. (2008) Automated cortical thickness measurements from MRI can accurately separate Alzheimer's patients from normal elderly controls. Neurobiol Aging 29, 23-30.

Lewczuk P., Kornhuber J., Vanderstichele H., Vanmechelen E., Esselmann H., Bibl M., Wolf S., Otto M., Reulbach U., Kolsch H., Jessen F., Schroder J., Schonknecht P., Hampel H., Peters O., Weimer E., Perneczky R., Jahn H., Luckhaus C., Lamla U., Supprian T., Maler J. M. and Wiltfang J. (2008) Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiol Aging 29, 812-818.

Lorenzl S., Buerger K., Hampel H. and Beal M. F. (2008) Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia. Int Psychogeriatr 20, 67-76.

McClain M. R., Palomaki G. E., Hampel H., Westman J. A. and Haddow J. E. (2008) Screen positive rates among six family history screening protocols for breast/ovarian cancer in four cohorts of women. Fam Cancer.

Omerovic M., Hampel H., Teipel S. J. and Buerger K. (2008) Pharmacological treatment of Alzheimer's dementia: state of the art and current dilemmas. World J Biol Psychiatry 9, 69-75.

South C. D., Hampel H., Comeras I., Westman J. A., Frankel W. L. and de la Chapelle A. (2008) The frequency of Muir-Torre syndrome among Lynch syndrome families. J Natl Cancer Inst 100, 277-281.

Teipel S. J., Meindl T., Grinberg L., Heinsen H. and Hampel H. (2008) Novel MRI techniques in the assessment of dementia. Eur J Nucl Med Mol Imaging 35 Suppl 1, S58-69.

Tran T., Hampel H., Qureshi W. A. and Shaib Y. (2007) Successful endoscopic management of bronchobiliary fistula due to radiofrequency ablation. Dig Dis Sci 52, 3178-3180.

Sydykova D., Stahl R., Dietrich O., Ewers M., Reiser M. F., Schoenberg S. O., Moller H. J., Hampel H. and Teipel S. J. (2007) Fiber connections between the cerebral cortex and the corpus callosum in Alzheimer's disease: a diffusion tensor imaging and voxel-based morphometry study. Cereb Cortex 17, 2276-2282.

Ewers M., Buerger K., Teipel S. J., Scheltens P., Schroder J., Zinkowski R. P., Bouwman F. H., Schonknecht P., Schoonenboom N. S., Andreasen N., Wallin A., DeBernardis J. F., Kerkman D. J., Heindl B., Blennow K. and Hampel H. (2007) Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI. Neurology 69, 2205-2212.
Bokde ALW, Lopez-Bajo P, Born C, Dong W, Meindl T, Leinsinger G, Teipel SJ, Faltraco F, Reiser M, Möller HJ, Hampel H. (2007) Functional abnormalities of the visual processing system in mild cognitive impaired subjects. Psychiatry Research – Neuroimaging.

Buerger K., Alafuzoff I., Ewers M., Pirttila T., Zinkowski R. and Hampel H. (2007) No correlation between CSF tau protein phosphorylated at threonine 181 with neocortical neurofibrillary pathology in Alzheimer's disease. Brain 130, e82.

Ernst A., Morgenthaler N. G., Buerger K., Dodel R., Noelker C., Sommer N., Schwarz M., Koehrle J., Bergmann A. and Hampel H. (2007) Procalcitonin is elevated in the cerebrospinal fluid of patients with dementia and acute neuroinflammation. J Neuroimmunol 189, 169-174.

Ewers M, Buerger K, Teipel SJ, Scheltens P, Schroeder J, Zinkowsky R, Bouwman FH, Schoenknecht P, Schoonenboom NSM, Andreasen N, DeBernardis JF, Kerkman DJ, Heindl B, Blennow K, Hampel H. (2007) Multicentre assessment of phosphorylated Tau in CSF for the prediction of conversion of MCI. Neurology.

Hampel H. (2007) Biochemical and neuroimaging markers in MCI and early Alzheimer’s disease. Silver Congress of the International Psychogeriatric Association. Osaka, Japan International Psychogeriatrics: The Official Journal of the International Psychogeriatric Association, Abstractband, 19(Suppl 1).

Shen Y; Zhong Z; Ewers M; Teipel S; Burger K; Wallin A; Blennow K; Hampel H. (2007)The levels of Beta-Secretase (BACE1) in cerebrospinal fluid of mild cognitive impairment. Silver Congress of the International Psychogeriatric Association, Osaka, Japan. International Psychogeriatrics: The Official Journal of the International Psychogeriatric Association, Abstractband. 19(Suppl 1).

Shen Y; Ewers M; Teipel S; Burger K; Wallin A; Blennow K; Zhong Z; He P; Mcallister C; Hampel H. (2007) Levels of Beta-Secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Silver Congress of the International Psychogeriatric Association, Osaka, Japan. International Psychogeriatrics: The Official Journal of the International Psychogeriatric Association, Abstractband, 19(Suppl 1).

Teipel S. J., Mitchell A. J., Moller H. J. and Hampel H. (2007a) Improving linear modeling of cognitive decline in patients with mild cognitive impairment: comparison of two methods. J Neural Transm Suppl, 241-247.

Teipel S. J., Bokde A. L., Born C., Meindl T., Reiser M., Moller H. J. and Hampel H. (2007b) Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study. Brain 130, 1745-1758.

Teipel S. J., Born C., Ewers M., Bokde A. L., Reiser M. F., Moller H. J. and Hampel H. (2007c) Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment. Neuroimage 38, 13-24.

Teipel S. J., Stahl R., Dietrich O., Schoenberg S. O., Perneczky R., Bokde A. L., Reiser M. F., Moller H. J. and Hampel H. (2007d) Multivariate network analysis of fiber tract integrity in Alzheimer's disease. Neuroimage 34, 985-995.

Dr. Orla Hardiman

Van Es, M. A., Van Vught, P. W., Veldink, J. H., Andersen, P. M., Birve, A., Lemmens, R., Cronin, S., Van Der Kooi, A. J., Visser, M. D., Schelhaas, H. J., Hardiman, O., Ragoussis, I., Lambrechts, D., Robberecht, W., Wokke, J. H., Ophoff, R. A., and Van Den Berg, L. H. (2009) Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis, Amyotroph Lateral Scler, 1-7.

Hardiman, O. (2009) Ten years of the ALS journal, Amyotroph Lateral Scler 10, 257.

Chio, A., Logroscino, G., Hardiman, O., Swingler, R., Mitchell, D., Beghi, E., and Traynor, B. G. (2009) Prognostic factors in ALS: A critical review, Amyotroph Lateral Scler 10, 310-323

Mohammad, A. F., Khan, K. A., Galvin, L., Hardiman, O., and O'Connell, P. G. (2009) High incidence of osteoporosis and fractures in an aging post-polio population, Eur Neurol 62, 369-374.

van Es, M. A., Veldink, J. H., Saris, C. G., Blauw, H. M., van Vught, P. W., Birve, A., Lemmens, R., Schelhaas, H. J., Groen, E. J., Huisman, M. H., van der Kooi, A. J., de Visser, M., Dahlberg, C., Estrada, K., Rivadeneira, F., Hofman, A., Zwarts, M. J., van Doormaal, P. T., Rujescu, D., Strengman, E., Giegling, I., Muglia, P., Tomik, B., Slowik, A., Uitterlinden, A. G., Hendrich, C., Waibel, S., Meyer, T., Ludolph, A. C., Glass, J. D., Purcell, S., Cichon, S., Nothen, M. M., Wichmann, H. E., Schreiber, S., Vermeulen, S. H., Kiemeney, L. A., Wokke, J. H., Cronin, S., McLaughlin, R. L., Hardiman, O., Fumoto, K., Pasterkamp, R. J., Meininger, V., Melki, J., Leigh, P. N., Shaw, C. E., Landers, J. E., Al-Chalabi, A., Brown, R. H., Jr., Robberecht, W., Andersen, P. M., Ophoff, R. A., and van den Berg, L. H. (2009) Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis, Nat Genet 41, 1083-1087.

Phukan, J., Ali, E., Pender, N. P., Molloy, F., Hennessy, M., Walsh, R. J., and Hardiman, O. (2009) Huntington's disease presenting as amyotrophic lateral sclerosis, Amyotroph Lateral Scler, 1-3.

Bedlack R. & Hardiman O. (2009) ALSUntangled (ALSU): a scientific approach to off-label treatment options for people with ALS using tweets and twitters. Amyotroph Lateral Scler, 10, 129-30.

Landers J. E., Melki J., Meininger V., Glass J. D., van den Berg L. H., van Es M. A., Sapp P. C., van Vught P. W., McKenna-Yasek D. M., Blauw H. M., Cho T. J., Polak M., Shi L., Wills A. M., Broom W. J., Ticozzi N., Silani V., Ozoguz A., Rodriguez-Leyva I., Veldink J.H., Ivinson A.J., Saris C.G., Hosler B.A., Barnes-Nessa A., Couture N., Wokke J. H., Kwiatkowski T. J., Jr., Ophoff R. A., Cronin S., Hardiman O., Diekstra F. P., Leigh P. N., Shaw C. E., Simpson C. L., Hansen V. K., Powell J. F., Corcia P., Salachas F., Heath S., Galan P., Georges F., Horvitz H. R., Lathrop M., Purcell S., Al-Chalabi A. & Brown R. H., Jr. (2009) Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A.

Donaghy C., Pinnock R., Abrahams S., Cardwell C., Hardiman O., Patterson V., McGivern R. C. & Gibson J. M. (2009) Ocular fixation instabilities in motor neurone disease. A marker of frontal lobe dysfunction? J Neurol, 256, 420-6.

McEvoy B. P., Montgomery G. W., McRae A. F., Ripatti S., Perola M., Spector T. D., Cherkas L., Ahmadi K. R., Boomsma D., Willemsen G., Hottenga J. J., Pedersen N. L., Magnusson P. K., Kyvik K. O., Christensen K., Kaprio J., Heikkila K., Palotie A., Widen E., Muilu J., Syvanen A. C., Liljedahl U., Hardiman O., Cronin S., Peltonen L., Martin N. G.& Visscher P. M. (2009) Geographical structure and differential natural selection among North European populations. Genome Res, 19, 804-14.
Phukan J. & Hardiman O. (2009) The management of amyotrophic lateral sclerosis. J Neurol, 256, 176-86.

Van Es M. A., Van Vught P. W., Veldink J. H., Andersen P. M., Birve A., Lemmens R., Cronin S., Van Der Kooi A. J., Visser M. D., Schelhaas H. J., Hardiman O., Ragoussis I., Lambrechts D., Robberecht W., Wokke J. H., Ophoff R. A. & Van Den Berg L. H. (2009) Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler, 1-7.

Cronin S., Tomik B., Bradley D. G., Slowik A. & Hardiman O. (2009) Screening for replication of genome-wide SNP associations in sporadic ALS. Eur J Hum Genet, 17, 213-8.

O'Sullivan E. P., Behan L. A., King T. F., Hardiman O. & Smith D. (2009) A case of stiff-person syndrome, type 1 diabetes, celiac disease and dermatitis herpetiformis. Clin Neurol Neurosurg, 111, 384-6.

Kieran D., Sebastia J., Greenway M. J., King M. A., Connaughton D., Concannon C. G., Fenner B., Hardiman O. & Prehn J. H. (2008) Control of motoneuron survival by angiogenin. J Neurosci, 28, 14056-61.

Chio A., Logroscino G., Hardiman O., Swingler R., Mitchell D., Beghi E. & Traynor B. G. (2008) Prognostic factors in ALS: A critical review. Amyotroph Lateral Scler, 1-14.

Cronin S., Blauw H. M., Veldink J. H., van Es M. A., Ophoff R. A., Bradley D. G., van den Berg L. H. and Hardiman O. (2008) Analysis of genome-wide copy number variation in Irish and Dutch ALS populations. Hum Mol Genet.

Cronin S., Greenway M. J., Andersen P. M. and Hardiman O. (2008) Screening of hypoxia-inducible genes in sporadic ALS. Amyotroph Lateral Scler, 1-7.

Fallis B. A. and Hardiman O. (2008) Aggregation of neurodegenerative disease in ALS kindreds. Amyotroph Lateral Scler, 1-4.

Cronin S., Berger S., Ding J., Schymick J. C., Washecka N., Hernandez D. G., Greenway M. J., Bradley D. G., Traynor B. J. and Hardiman O. (2008) A genome-wide association study of sporadic ALS in a homogenous Irish population. Hum Mol Genet 17, 768-774.

del Barco D. G., Berlanga J., Penton E., Hardiman O. and Montero E. (2008) Boosting controlled autoimmunity: a new therapeutic target for CNS disorders. Expert Rev Neurother 8, 819-825

Donaghy C., Dick A., Hardiman O. and Patterson V. (2008) Timeliness of diagnosis in motor neurone disease: a population-based study. Ulster Med J 77, 18-21.

Logroscino G., Traynor B. J., Hardiman O., Chio A., Couratier P., Mitchell J. D., Swingler R. J. and Beghi E. (2008) Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues. J Neurol Neurosurg Psychiatry 79, 6-11.
O'Toole O., Traynor B. J., Brennan P., Sheehan C., Frost E., Corr B. and Hardiman O. (2008) Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004. J Neurol Neurosurg Psychiatry.

Phukan J., Pender N. P. and Hardiman O. (2007) Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurol 6, 994-1003.

Longroscino G, Traynor BJ, Hardiman O, Mitchell D, Swingler R, Beghi E (on behalf of EURALS) (2007)Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues. J Neurol Neurosurg Psychiatry.

Andersen P. M., Borasio G. D., Dengler R., Hardiman O., Kollewe K., Leigh P. N., Pradat P. F., Silani V. and Tomik B. (2007) Good practice in the management of amyotrophic lateral sclerosis: clinical guidelines. An evidence-based review with good practice points. EALSC Working Group. Amyotroph Lateral Scler 8, 195-213.

Cronin S., Hardiman O. and Traynor B. J. (2007a) Ethnic variation in the incidence of ALS: a systematic review. Neurology 68, 1002-1007.

Cronin S., Greenway M. J., Prehn J. H. and Hardiman O. (2007b) Paraoxonase
promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 78, 984-986.

Foley G., O'Mahony P. and Hardiman O. (2007) Perceptions of quality of life in people with ALS: effects of coping and health care. Amyotroph Lateral Scler 8, 164-169.

Hardiman O. and Greenway M. (2007) The complex genetics of amyotrophic lateral sclerosis. Lancet Neurol 6, 291-292.

Hosback S., Hardiman O., Nolan C. M., Doyle M. A., Gorman G., Lynch C., O'Toole O. and Jakeman P. (2007) Circulating insulin-like growth factors and related binding proteins are selectively altered in amyotrophic lateral sclerosis and multiple sclerosis. Growth Horm IGF Res.

Logroscino G., Beghi E., Hardiman O., Chio A., Mitchell J. D., Swingler R. J. and Traynor B. (2007) Effect of referral bias on assessing survival in als. Neurology 69, 939; author reply 939-940.

McKeon A., Ozelius L. J., Hardiman O., Greenway M. J. and Pittock S. J. (2007) Heterogeneity of presentation and outcome in the Irish rapid-onset dystonia-Parkinsonism kindred. Mov Disord 22, 1325-1327.

Meldrum D., Cahalane E., Conroy R., Fitzgerald D. and Hardiman O. (2007) Maximum voluntary isometric contraction: reference values and clinical application. Amyotroph Lateral Scler 8, 47-55.

Meldrum D., Cahalane E., Conroy R., Guthrie R. and Hardiman O. (2007) Quantitative assessment of motor fatigue: normative values and comparison with prior-polio patients. Amyotroph Lateral Scler 8, 170-176.
Ryan A. M., Ryan J., Wan-Ahmed M., Hardiman O., Farrell M. A., McNamara B. and Sweeney B. J. (2007) Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease. J Neurol Neurosurg Psychiatry 78, 98-99.

Schymick J. C., Yang Y., Andersen P. M., Vonsattel J. P., Greenway M., Momeni P., Elder J., Chio A., Restagno G., Robberecht W., Dahlberg C., Mukherjee O., Goate A., Graff-Radford N., Caselli R. J., Hutton M., Gass J., Cannon A., Rademakers R., Singleton A. B., Hardiman O., Rothstein J., Hardy J. and Traynor B. J. (2007) Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes. J Neurol Neurosurg Psychiatry 78, 754-756.

Dr. Andrew Harkin

Durkin S., Prendergast A. & Harkin A. (2008) Reduced efficacy of fluoxetine following MDMA ("Ecstasy")-induced serotonin loss in rats. Prog Neuropsychopharmacol Biol Psychiatry, 32, 1894-901.

Roche M., Shanahan E., Harkin A. and Kelly J. P. (2008) Trans-species assessment of antidepressant activity in a rodent model of depression. Pharmacol Rep 60, 404-408.

Garland M. R., Hallahan B., McNamara M., Carney P. A., Grimes H., Hibbeln J. R., Harkin A. and Conroy R. M. (2007) Lipids and essential fatty acids in patients presenting with self-harm. Br J Psychiatry 190, 112-117.

McNamara R., Maginn M. and Harkin A. (2007) Caffeine induces a profound and persistent tachycardia in response to MDMA ("Ecstasy") administration. Eur J Pharmacol 555, 194-198.

Roche M., Harkin A. and Kelly J. P. (2007) Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat. Neuropsychopharmacology 32, 1312-1320.

Prof. Pete Humphries

Bartsch U., Oriyakhel W., Kenna P. F., Linke S., Richard G., Petrowitz B., Humphries P., Farrar G. J. and Ader M. (2008) Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice. Exp Eye Res 86, 691-700.
Tam L. C., Kiang A. S., Kennan A., Kenna P. F., Chadderton N., Ader M., Palfi A., Aherne A., Campbell M., Reynolds A., McKee A., Humphries M. M., Farrar J. and Humphries P. (2008) Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10). Hum Mol Genet.

Reynolds A. L., Farrar G. J., Humphries P. and Kenna P. F. (2008) Variation in the electroretinogram of C57BL/6 substrains of mouse. Adv Exp Med Biol 613, 383-391.

Allen D., Winters E., Kenna P. F., Humphries P. and Farrar G. J. (2008) Reference gene selection for real-time rtPCR in human epidermal keratinocytes. J Dermatol Sci 49, p.217-225.

Campbell M., Humphries M., Kenna P., Humphries P. and Brankin B. (2007) Altered expression and interaction of adherens junction proteins in the developing OLM of the Rho(-/-) mouse. Exp Eye Res 85, p.714-720.

Loscher, C.J., Hokamp, K., Kenna, P.F., Ivens, A.C., Humphries P., Palfi A, Farrar GJ. (2007) Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa.

Aherne A., Kennan A., Kenna P. F., McNally N., Farrar G. J. and Humphries P. (2006) Molecular mechanisms of photoreceptor degeneration in RP caused by IMPDH1 mutations. Adv Exp Med Biol 572, 81-87.

Allen, D., Kenna, P. F., Palfi, A., McMahon, H. P., Millington-Ward, S., O'Reilly, M., Humphries, P. and Farrar, G. J. (2007) Development of strategies for conditional RNA interference. J Gene Med 9, 287-298.

Dr. Aine Kelly

Griffin E. W., Bechara R. G., Birch A. M. & Kelly A. M. (2009) Exercise enhances hippocampal-dependent learning in the rat: Evidence for a BDNF-related mechanism. Hippocampus, 19(10):973-80

O'Callaghan R. M., Griffin E. W. & Kelly A. M. (2009) Long-term treadmill exposure protects against age-related neurodegenerative change in the rat hippocampus. Hippocampus, 19(10):1019-29

Hennigan A., Callaghan C. K., Kealy J., Rouine J. & Kelly A. M. (2009) Deficits in LTP and recognition memory in the genetically hypertensive rat are associated with decreased expression of neurotrophic factors and their receptors in the dentate gyrus. Behav Brain Res, 197, 371-7.

Larkin, A. E., Fahey, B., Gobbo, O., Callaghan, C. K., Cahill, E., O'Mara, S. M., Kelly, Á. M., (2008) Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat, Brain Res 1199: 126 – 132.

Hennigan A., O’Callaghan R. M., Kelly Á. M. (2007) Neurotrophins and their receptors: roles in plasticity, neurodegeneration and neuroprotection, Biochem Soc Trans 35: 424-427.

Hennigan A., Trotter C., KellyÁ. M. (2007) Lipopolysaccharide impairs long-term potentiation and recognition memory and increases p75NTR expression in the rat dentate gyrus, Brain Res 1130:158-166.

O'Callaghan R. M., Ohle R., Kelly Á. M. (2007) The effects of forced exercise on hippocampal plasticity in the rat: a comparison of LTP, spatial- and non-spatial learning, Behavioral Brain Res 176: 362-366.

Dr Paul Kenna

Bujakowska, K., Maubaret, C., Chakarova, C. F., Tanimoto, N., Beck, S. C., Fahl, E., Humphries, M. M., Kenna, P. F., Makarov, E., Makarova, O., Paquet-Durand, F., Ekstrom, P. A., van Veen, T., Leveillard, T., Humphries, P., Seeliger, M. W., and Bhattacharya, S. S. (2009) Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP), Invest Ophthalmol Vis Sci 50, 5927-5933.

Tam L. C., Kiang A. S., Kennan A., Kenna P. F., Chadderton N., Ader M., Palfi A., Aherne A., Campbell M., Reynolds A., McKee A., Humphries M. M., Farrar J. and Humphries P. (2008) Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10). Hum Mol Genet. 17(14):2084-2100

Reynolds A. L., Farrar G. J., Humphries P. and Kenna P. F. (2008) Variation in the electroretinogram of C57BL/6 substrains of mouse. Adv Exp Med Biol 613, 383-391.

Allen D., Winters E., Kenna P. F., Humphries P. and Farrar G. J. (2008) Reference gene selection for real-time rtPCR in human epidermal keratinocytes. J Dermatol Sci 49, 217-225.

Dr. Christian Kerskens

Cooke, J. M., Kalmykov, Y. P., Coffey, W. T., and Kerskens, C. M. (2009) Langevin equation approach to diffusion magnetic resonance imaging, Phys Rev E Stat Nonlin Soft Matter Phys 80, 061102.

Brunecker P., Endres M., Nolte C. H., Schultze J., Wegener S., Jungehulsing G. J., Muller B., Kerskens C. M., Fiebach J. B., Villringer A. and Steinbrink J. (2008) Evaluation of an AIF correction algorithm for dynamic susceptibility contrast-enhanced perfusion MRI. Magn Reson Med 60, 102-110.

Corr S. A., Byrne S. J., Tekoriute R., Meledandri C. J., Brougham D. F., Lynch M., Kerskens C., O'Dwyer L. and Gun'ko Y. K. (2008) Linear assemblies of magnetic nanoparticles as MRI contrast agents. J Am Chem Soc 130, 4214-4215.

Dr. Julie Kelly

Kelly, J. A., Lucia, M. S., and Lambert, J. R. (2009) p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms, Cancer Lett 277, 38-47.

Hogan N., O'Boyle K. M., Hinkle P. M. & Kelly J. A. (2008) A novel TRH analog, Glp-Asn-Pro-D-Tyr-D-TrpNH2, binds to [3H][3-Me-His2]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expressing TRHR1 or TRHR2. Neurosci Lett, 431, 26-30.

Scalabrino G. A., Hogan N., O'Boyle K. M., Slator G. R., Gregg D. J., Fitchett C. M., Draper S. M., Bennett G. W., Hinkle P. M., Bauer K., Williams C. H., Tipton K. F. and Kelly J. A. (2007) Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone. Neuropharmacology 52, 1472-1481.

Prof. Rose Anne Kenny

Richardson, J., Kerr, S. R., Shaw, F., Kenny, R. A., O'Brien, J. T., and Thomas, A. J. (2009) A study of orthostatic hypotension in late-life depression, Am J Geriatr Psychiatry 17, 996-999.

Finucane, C., Boyle, G., Fan, C. W., Hade, D., Byrne, L., and Kenny, R. A. (2010) Mayer wave activity in vasodepressor carotid sinus hypersensitivity, Europace 12, 247-253.

Romero-Ortuno, R., Cogan, L., Foran, T., Fan, C. W., and Kenny, R. A. (2010) Using the Finometer to examine sex differences in hemodynamic responses to orthostasis in older people, Blood Press Monit 15, 8-17.

Romero-Ortuno, R., Cogan, L., Cunningham, C. U., and Kenny, R. A. (2010) Do older pedestrians have enough time to cross roads in Dublin? A critique of the Traffic Management Guidelines based on clinical research findings, Age Ageing 39, 80-86.

Romero-Ortuno, R., Cogan, L., Fan, C. W., and Kenny, R. A. (2010) Intolerance to initial orthostasis relates to systolic BP changes in elders, Clin Auton Res 20, 39-45.

Moya, A., Sutton, R., Ammirati, F., Blanc, J. J., Brignole, M., Dahm, J. B., Deharo, J. C., Gajek, J., Gjesdal, K., Krahn, A., Massin, M., Pepi, M., Pezawas, T., Granell, R. R., Sarasin, F., Ungar, A., van Dijk, J. G., Walma, E. P., Wieling, W., Abe, H., Benditt, D. G., Decker, W. W., Grubb, B. P., Kaufmann, H., Morillo, C., Olshansky, B., Parry, S. W., Sheldon, R., Shen, W. K., Vahanian, A., Auricchio, A., Bax, J., Ceconi, C., Dean, V., Filippatos, G., Funck-Brentano, C., Hobbs, R., Kearney, P., McDonagh, T., McGregor, K., Popescu, B. A., Reiner, Z., Sechtem, U., Sirnes, P. A., Tendera, M., Vardas, P., Widimsky, P., Acarturk, E., Andreotti, F., Asteggiano, R., Bauersfeld, U., Bellou, A., Benetos, A., Brandt, J., Chung, M. K., Cortelli, P., Da Costa, A., Extramiana, F., Ferro, J., Gorenek, B., Hedman, A., Hirsch, R., Kaliska, G., Kenny, R. A., Kjeldsen, K. P., Lampert, R., Molgard, H., Paju, R., Puodziukynas, A., Raviele, A., Roman, P., Scherer, M., Schondorf, R., Sicari, R., Vanbrabant, P., Wolpert, C., and Zamorano, J. L. (2009) Guidelines for the diagnosis and management of syncope (version 2009): the Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC), Eur Heart J 30, 2631-2671.

Miller, V. M., Kenny, R. A., Oakley, A. E., Hall, R., Kalaria, R. N., and Allan, L. M. (2009) Dorsal motor nucleus of vagus protein aggregates in Lewy body disease with autonomic dysfunction, Brain Res 1286, 165-173.

Allan, L. M., Ballard, C. G., Rowan, E. N., and Kenny, R. A. (2009) Incidence and prediction of falls in dementia: a prospective study in older people, PLoS One 4, e5521.

McAuley, M. T., Kenny, R. A., Kirkwood, T. B., Wilkinson, D. J., Jones, J. J., and Miller, V. M. (2009) A mathematical model of aging-related and cortisol induced hippocampal dysfunction, BMC Neurosci 10, 26.

McCarthy, F., McMahon, C. G., Geary, U., Plunkett, P. K., Kenny, R. A., and Cunningham, C. J. (2009) Management of syncope in the Emergency Department: a single hospital observational case series based on the application of European Society of Cardiology Guidelines, Europace 11, 216-224.

Moya A., Sutton R., Ammirati F., Blanc J.J., Brignole M., Dahm J.B., Deharo J.C., Gajek J., Gjesdal K., Krahn A., Massin M., Pepi M., Pezawas T., Granell R.R., Sarasin F., Ungar A., van Dijk J.G., Walma E.P., Wieling W., Abe H., Benditt D.G., Decker W.W., Grubb B.P., Kaufmann H., Morillo C., Olshansky B., Parry S.W., Sheldon R., Shen W.K., Vahanian A., Auricchio A., Bax J., Ceconi C., Dean V., Filippatos G., Funck-Brentano C., Hobbs R., Kearney P., McDonagh T., McGregor K., Popescu B.A., Reiner Z., Sechtem U., Sirnes P.A., Tendera M., Vardas P., Widimsky P., Acarturk E., Andreotti F., Asteggiano R., Bauersfeld U., Bellou A., Benetos A., Brandt J., Chung M.K., Cortelli P., Da Costa A., Extramiana F., Ferro J., Gorenek B., Hedman A., Hirsch R., Kaliska G., Kenny R.A., Kjeldsen K.P., Lampert R., Molgard H., Paju R., Puodziukynas A., Raviele A., Roman P., Scherer M., Schondorf R., Sicari R., Vanbrabant P., Wolpert C. & Zamorano J.L. (2009) Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC). Eur Heart J.

Miller V.M., Kenny R.A., Oakley A.E., Hall R., Kalaria R.N. & Allan L.M. (2009) Dorsal motor nucleus of vagus protein aggregates in Lewy body disease with autonomic dysfunction. Brain Res, 1286, 165-73.

Allan L. M., Ballard C. G., Rowan E. N. & Kenny R. A. (2009) Incidence and prediction of falls in dementia: a prospective study in older people. PLoS ONE, 4, e5521.

McAuley M. T., Kenny R. A., Kirkwood T. B., Wilkinson D. J., Jones J. J. & Miller V. M. (2009) A mathematical model of aging-related and cortisol induced hippocampal dysfunction. BMC Neurosci, 10, 26.

McCarthy F., McMahon C. G., Geary U., Plunkett P. K., Kenny R. A. & Cunningham C. J. (2009) Management of syncope in the Emergency Department: a single hospital observational case series based on the application of European Society of Cardiology Guidelines. Europace, 11, 216-24.

Romero-Ortuno R. and Kenny R. A. (2008) Is it cardiac? Assessment of syncope with a scoring system. Heart.

Parry S. W., Gray J. C., Newton J. L., Reeve P., O'Shea D. and Kenny R. A. (2008) 'Front-loaded' head-up tilt table testing: validation of a rapid first line nitrate-provoked tilt protocol for the diagnosis of vasovagal syncope. Age Ageing 37, 411-415.

Kenny R. A. (2008) Remote technology used to monitor signs of ageing. Interview by Thelma Agnew. Nurs Older People 20, 6-7.

Allcock L. M., Rowan E. N., Steen I. N., Wesnes K., Kenny R. A. and Burn D. J. (2008) Impaired attention predicts falling in Parkinson's disease. Parkinsonism Relat Disord.

McMahon C. G., Kenny R., Bennett K. and Kirkman E. (2008) Modification of acute cardiovascular homeostatic responses to hemorrhage following mild to moderate traumatic brain injury. Crit Care Med 36, 216-224.

Parry S. W., Frearson R., Steen N., Newton J. L., Tryambake P. and Kenny R. A. (2008) Evidence-based algorithms and the management of falls and syncope presenting to acute medical services. Clin Med 8, 157-162.

Miller V. M., Kenny R. A., Slade J. Y., Oakley A. E. and Kalaria R. N. (2008) Medullary autonomic pathology in carotid sinus hypersensitivity. Neuropathol Appl Neurobiol 34, 403-411.

Rowan E. N., Dickinson H. O., Stephens S., Ballard C., Kalaria R. and Kenny R. A. (2007) Homocysteine and post-stroke cognitive decline. Age Ageing 36, 339-343.

Allan L. M., Ballard C. G., Allen J., Murray A., Davidson A. W., McKeith I. G. and Kenny R. A. (2007) Autonomic dysfunction in dementia. J Neurol Neurosurg Psychiatry 78, 671-677.

Firbank M. J., Burton E. J., Barber R., Stephens S., Kenny R. A., Ballard C., Kalaria R. N. and O'Brien J. T. (2007) Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors. Neurobiol Aging 28, 1664-1669.

Li S., Cullen W. K., Anwyl R. and Rowan M. J. (2007) Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 144, 754-761.

Miller V. M., Kalaria R. N., Hall R., Oakley A. E. and Kenny R. A. (2007) Medullary microvessel degeneration in multiple system atrophy. Neurobiol Dis 26, 615-622.

Rowan E. N., Dickinson H. O., Stephens S., Ballard C., Kalaria R. and Kenny R. A. (2007) Homocysteine and post-stroke cognitive decline. Age Ageing 36, 339-343.

Prof. Brian Lawlor

Gallagher, D., Mhaolain, A. N., Greene, E., Walsh, C., Denihan, A., Bruce, I., Golden, J., Conroy, R. M., Kirby, M., and Lawlor, B. A. (2009) Late life depression: a comparison of risk factors and symptoms according to age of onset in community dwelling older adults, Int J Geriatr Psychiatry.

Golden J., Conroy R. M. & Lawlor B. A. (2009) Social support network structure in older people: underlying dimensions and association with psychological and physical health. Psychol Health Med, 14, 280-90.

Golden J., Conroy R. M., Bruce I., Denihan A., Greene E., Kirby M. & Lawlor B. A. (2009) Loneliness, social support networks, mood and wellbeing in community-dwelling elderly. Int J Geriatr Psychiatry.

Blanco-Campal A., Coen R. F., Lawlor B. A., Walsh J. B. & Burke T. E. (2009) Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task. J Int Neuropsychol Soc, 15, 154-9.

Chin A. V., Robinson D. J., O'Connell H., Hamilton F., Bruce I., Coen R., Walsh B., Coakley D., Molloy A., Scott J., Lawlor B. A. and Cunningham C. J. (2008) Vascular biomarkers of cognitive performance in a community-based elderly population: the Dublin Healthy Ageing study. Age Ageing 37, 559-564.

Luanaigh C. O. and Lawlor B. A. (2008) Loneliness and the health of older people. Int J Geriatr Psychiatry.

Irish M., Lawlor B.A., O'Mara S. M. and Coen R. F. (2008) Assessment of behavioural markers of autonoetic consciousness during episodic autobiographical memory retrieval: A preliminary analysis. Behav Neurol 19, 3-6.

Cahill S., Clark M., O'Connell H., Lawlor B., Coen R. F. and Walsh C. (2008) The attitudes and practices of general practitioners regarding dementia diagnosis in Ireland. Int J Geriatr Psychiatry 23, 663-669.

Lynch C. A., Moran M. and Lawlor B. A. (2008) Firearms and dementia: a smoking gun? Int J Geriatr Psychiatry 23, 1-6.
Lynch C. A., Brazil J., Cullen B., Coakley D., Gill M., Lawlor B. A. and Hawi Z. (2008) Apolipoprotein E promoter polymorphisms (-491A/T and -427T/C) and Alzheimer's disease: no evidence of association in the Irish population. Ir J Med Sci 177, 29-33.

Cullen B., O'Neill B., Evans J. J., Coen R. F. and Lawlor B. A. (2007) A review of screening tests for cognitive impairment. J Neurol Neurosurg Psychiatry 78, 790-799.
Golden J. and Lawlor B. (2006) Treatment of dementia in the community. Bmj 333, 1184-1185.

Professor Marina Lynch

Prof. Marina Lynch Lynch M.A. (2009) The multifaceted profile of activated microglia. Mol Neurobiol, 40, 139-56.

Lyons A., Lynch A.M., Downer E.J., Hanley R., O'Sullivan J.B., Smith A. & Lynch M.A. (2009) Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro. J Neurochem, 110, 1547-56.

Martin D.S., Walsh M., Miller A.M., Skerrett H.E., Byrne P., Mandel A., Bolton A.E. & Lynch M.A. (2009) A novel phospholipid-based drug formulation, VP025, modulates age- and LPS-induced microglial activity in the rat. Neuroimmunomodulation, 16, 400-10.

Lyons A., McQuillan K., Deighan B.F., O'Reilly J.A., Downer E.J., Murphy A.C., Watson M., Piazza A., O'Connell F., Griffin R., Mills K.H. & Lynch M.A. (2009) Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide. Brain Behav Immun, 23, 1020- 7.

Downer E. J., Cowley T. R., Cox F., Maher F. O., Berezin V., Bock E. & Lynch M. A. (2009) A synthetic NCAM-derived mimetic peptide, FGL, exerts antiinflammatory properties via IGF-1 and interferon-gamma modulation. J Neurochem, 109, 1516-25.

Piazza A. & Lynch M. A. (2009) Neuroinflammatory changes increase the impact of stressors on neuronal function. Biochem Soc Trans, 37, 303-7.

Miller A. M., Piazza A., Martin D. S., Walsh M., Mandel A., Bolton A. E. & Lynch M. A. (2009) The deficit in long-term potentiation induced by chronic administration of amyloid-beta is attenuated by treatment of rats with a novel phospholipid-based drug formulation, VP025. Exp Gerontol, 44, 300-4.

Schmid A. W., Lynch M. A. & Herron C. E. (2008) The effects of IL-1 receptor antagonist on beta amyloid mediated depression of LTP in the rat CA1 in vivo. Hippocampus. Lynch M. A. (2008) The risky business of ageing. Brain Behav Immun 22, 299-300.

Downer E. J., Cowley T. R., Lyons A., Mills K. H., Berezin V., Bock E. and Lynch M. A. (2008) A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL. Neurobiol Aging.

Clarke R. M., O'Connell F., Lyons A. and Lynch M. A. (2007a) The HMG-CoA reductase inhibitor, atorvastatin, attenuates the effects of acute administration of amyloid-beta1-42 in the rat hippocampus in vivo. Neuropharmacology 52, 136-145.

Clarke R. M., Lyons A., O'Connell F., Deighan B. F., Barry C. E., Anyakoha N. G., Nicolaou A. and Lynch M. A. (2008) A pivotal role for IL-4 in atorvastatin-associated neuroprotection in rat brain.

J Biol Chem. Loane D. J., Deighan B. F., Clarke R. M., Griffin R. J., Lynch A. M. and Lynch M. A. (2007) Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol Aging.

Lynch A. M., Loane D. J., Minogue A. M., Clarke R. M., Kilroy D., Nally R. E., Roche O. J., O'Connell F. and Lynch M. A. (2007) Eicosapentaenoic acid confers neuroprotection in the amyloid-beta challenged aged hippocampus. Neurobiol Aging 28, 845-855.

Lyons A., Griffin R. J., Costelloe C. E., Clarke R. M. and Lynch M. A. (2007) IL-4 attenuates the neuroinflammation induced by amyloid-beta in vivo and in vitro. J Neurochem 101, 771-781.

Lyons A., Downer E. J., Crotty S., Nolan Y. M., Mills K. H. and Lynch M. A. (2007) CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4. J Neurosci 27, 8309-8313.

Minogue A. M., Lynch A. M., Loane D. J., Herron C. E. and Lynch M. A. (2007) Modulation of amyloid-beta-induced and age-associated changes in rat hippocampus by eicosapentaenoic acid. J Neurochem 103, 914-926.

Moore M., Piazza A., Nolan Y. and Lynch M. A. (2007) Treatment with dexamethasone and vitamin D3 attenuates neuroinflammatory age-related changes in rat hippocampus. Synapse 61, 851-861.

Dr. Aileen Maria Lynch

Lyons, A., Lynch, A. M., Downer, E. J., Hanley, R., O'Sullivan, J. B., Smith, A., and Lynch, M. A. (2009) Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro, J Neurochem 110, 1547-1556.

Loane, D. J., Deighan, B. F., Clarke, R. M., Griffin, R. J., Lynch, A. M., and Lynch, M. A. (2009) Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain, Neurobiol Aging 30, 920-931.

Loane D. J., Deighan B. F., Clarke R. M., Griffin R. J., Lynch A. M. & Lynch M. A. (2009) Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol Aging, 30, 920-31.

Loane D. J., Deighan B. F., Clarke R. M., Griffin R. J., Lynch A. M. and Lynch M. A. (2007) Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol Aging.

Lynch M.A. (2009) The multifaceted profile of activated microglia. Mol Neurobiol, 40, 139-56.

Downer E. J., Cowley T. R., Cox F., Maher F. O., Berezin V., Bock E. & Lynch M. A. (2009) A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-gamma modulation. J Neurochem, 109, 1516-25.

Piazza A. & Lynch M. A. (2009) Neuroinflammatory changes increase the impact of stressors on neuronal function. Biochem Soc Trans, 37, 303-7.

Schmid A. W., Lynch M. A. & Herron C. E. (2008) The effects of IL-1 receptor antagonist on beta amyloid mediated depression of LTP in the rat CA1 in vivo. Hippocampus.

Lynch M. A. (2008) The risky business of ageing. Brain Behav Immun 22, 299-300.

Downer E. J., Cowley T. R., Lyons A., Mills K. H., Berezin V., Bock E. and Lynch M. A. (2008) A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL. Neurobiol Aging.

Costelloe C., Watson M., Murphy A., McQuillan K., Loscher C., Armstrong M. E., Garlanda C., Mantovani A., O'Neill L. A., Mills K. H. and Lynch M. A. (2008) IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J Neurochem 105, 1960-1969.
Clarke R. M., O'Connell F., Lyons A. and Lynch M. A. (2007a) The HMG-CoA reductase inhibitor, atorvastatin, attenuates the effects of acute administration of amyloid-beta1-42 in the rat hippocampus in vivo. Neuropharmacology 52, 136-145.

Clarke R. M., Lyons A., O'Connell F., Deighan B. F., Barry C. E., Anyakoha N. G., Nicolaou A. and Lynch M. A. (2008) A pivotal role for IL-4 in atorvastatin-associated neuroprotection in rat brain. J Biol Chem.

Loane D. J., Deighan B. F., Clarke R. M., Griffin R. J., Lynch A. M. and Lynch M. A. (2007) Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol Aging.

Lyons A., Griffin R. J., Costelloe C. E., Clarke R. M. and Lynch M. A. (2007) IL-4 attenuates the neuroinflammation induced by amyloid-beta in vivo and in vitro. J Neurochem 101, 771-781.

Moore M., Piazza A., Nolan Y. and Lynch M. A. (2007) Treatment with dexamethasone and vitamin D3 attenuates neuroinflammatory age-related changes in rat hippocampus. Synapse 61, 851-861.

Prof. Declan McLoughlin

Kavanagh, A., and McLoughlin, D. M. (2009) Electroconvulsive therapy and nursing care, Br J Nurs 18, 1370, 1372, 1374-1377.

Mitchell J.C., Ariff B.B., Yates D.M., Lau K.F., Perkinton M.S., Rogelj B., Stephenson J.D., Miller C.C. & McLoughlin D.M. (2009) X11{beta} rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice. Hum Mol Genet.

McLoughlin D.M. (2009) Review: high frequency repetitive transcranial magnetic stimulation improves symptoms of major depression. Evid Based Ment Health, 12, 80-1.

Stevenson A., Yates D. M., Manser C., De Vos K. J., Vagnoni A., Leigh P. N., McLoughlin D. M. & Miller C. C. (2009) Riluzole protects against glutamate-induced slowing of neurofilament axonal transport. Neurosci Lett, 454, 161-4.

Yates D. M., Manser C., De Vos K. J., Shaw C. E., McLoughlin D. M. & Miller C. C. (2009) Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments. Eur J Cell Biol, 88, 193-202.

Lau K. F., Chan W. M., Perkinton M. S., Tudor E. L., Chang R. C., Chan H. Y., McLoughlin D. M. & Miller C. C. (2008) Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription. J Biol Chem, 283, 34728-37.

Manser C., Stevenson A., Banner S., Davies J., Tudor E. L., Ono Y., Leigh P. N., McLoughlin D. M., Shaw C. E. and Miller C. C. (2008) Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport. FEBS Lett 582, 2303-2308.

McLoughlin D. M. (2008) Vagus rules still apply. Psychol Med 38, 625-627.

Eranti S. V., Mogg A. J., Pluck G. C., Landau S. and McLoughlin D. M. (2008) Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: A naturalistic comparison study. J Affect Disord. 113(1-2):165-71

Knapp M., Romeo R., Mogg A., Eranti S., Pluck G., Purvis R., Brown R. G., Howard R., Philpot M., Rothwell J., Edwards D. and McLoughlin D. M. (2008) Cost-effectiveness of transcranial magnetic stimulation vs. electroconvulsive therapy for severe depression: A multi-centre randomised controlled trial. J Affect Disord. 109(3):273-85

McLoughlin D. M. and Miller C. C. (2008) The FE65 proteins and Alzheimer's disease. J Neurosci Res 86, 744-754.

Mogg A., Pluck G., Eranti S. V., Landau S., Purvis R., Brown R. G., Curtis V., Howard R., Philpot M. and McLoughlin D. M. (2008) A randomized controlled trial with 4-month follow-up of adjunctive repetitive transcranial magnetic stimulation of the left prefrontal cortex for depression. Psychol Med 38, 323-333.

De Vos K. J., Chapman A. L., Tennant M. E., Manser C., Tudor E. L., Lau K. F., Brownlees J., Ackerley S., Shaw P. J., McLoughlin D. M., Shaw C. E., Leigh P. N., Miller C. C. and Grierson A. J. (2007) Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum Mol Genet 16, 2720-2728.

Eranti S., Mogg A., Pluck G., Landau S., Purvis R., Brown R. G., Howard R., Knapp M., Philpot M., Rabe-Hesketh S., Romeo R., Rothwell J., Edwards D. and McLoughlin D. M. (2007) A randomized, controlled trial with 6-month follow-up of repetitive transcranial magnetic stimulation and electroconvulsive therapy for severe depression. Am J Psychiatry 164, 73-81.

McLoughlin D. M. and Miller C. C. (2007) The FE65 proteins and Alzheimer's disease. J Neurosci Res.

McLoughlin D. M., Mogg A., Eranti S., Pluck G., Purvis R., Edwards D., Landau S., Brown R., Rabe-Heskith S., Howard R., Philpot M., Rothwell J., Romeo R. and Knapp M. (2007) The clinical effectiveness and cost of repetitive transcranial magnetic stimulation versus electroconvulsive therapy in severe depression: a multicentre pragmatic randomised controlled trial and economic analysis. Health Technol Assess 11, 1-54.

Mogg A., Purvis R., Eranti S., Contell F., Taylor J. P., Nicholson T., Brown R. G. and McLoughlin D. M. (2007) Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: a randomized controlled pilot study. Schizophr Res 93, 221-228.

Mogg A., Pluck G., Eranti S. V., Landau S., Purvis R., Brown R. G., Curtis V., Howard R., Philpot M. and McLoughlin D. M. (2007) A randomized controlled trial with 4-month follow-up of adjunctive repetitive transcranial magnetic stimulation of the left prefrontal cortex for depression. Psychol Med, 1-11.

Prof. Kingston Mills

Mills, K. H., and Dunne, A. (2009) Immune modulation: IL-1, master mediator or initiator of inflammation, Nat Med 15, 1363-1364.

Fletcher, J. M., Lonergan, R., Costelloe, L., Kinsella, K., Moran, B., O'Farrelly, C., Tubridy, N., and Mills, K. H. (2009) CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis, J Immunol 183, 7602-7610.

Reynolds, C. M., Draper, E., Keogh, B., Rahman, A., Moloney, A. P., Mills, K. H., Loscher, C. E., and Roche, H. M. (2009) A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4, J Nutr 139, 2351-2357.

Sutton C.E., Lalor S.J., Sweeney C.M., Brereton C.F., Lavelle E.C. & Mills K.H. (2009) Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity, 31, 331-41.

Walsh K.P., Brady M.T., Finlay C.M., Boon L. & Mills K.H. (2009) Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J Immunol, 183, 1577-86.

Brereton C.F., Sutton C.E., Lalor S.J., Lavelle E.C. & Mills K.H. (2009) Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease. J Immunol, 183, 1715-23.

de Roos B., Rungapamestry V., Ross K., Rucklidge G., Reid M., Duncan G., Horgan G., Toomey S., Browne J., Loscher C.E., Mills K.H. & Roche H.M. (2009) Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet. Proteomics, 9, 3244-56.

Dunne P.J., Moran B., Cummins R.C. & Mills K.H. (2009) CD11c+CD8alpha+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis. J Immunol, 183, 400-10.

Mills K. H. (2009) Designer adjuvants for enhancing the efficacy of infectious disease and cancer vaccines based on suppression of regulatory T cell induction. Immunol Lett, 122, 108-11.

Mills K. H. 2008) Induction, function and regulation of IL-17-producing T cells. Eur J Immunol, 38, 2636-49.

Mills K. H. (2008) TLR9 turns the tide on Treg cells. Immunity, 29, 518-20.

Rowan A. G., Fletcher J. M., Ryan E. J., Moran B., Hegarty J. E., O'Farrelly C. & Mills K. H. (2008) Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. J Immunol, 181, 4485-94.

Toomey D., Conroy H., Jarnicki A. G., Higgins S. C., Sutton C. & Mills K. H. (2008) Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma. Vaccine, 26, 3540-9.

Conroy H., Marshall N. A. and Mills K. H. (2008) TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours. Oncogene 27, 168-180.

Downer E. J., Cowley T. R., Lyons A., Mills K. H., Berezin V., Bock E. and Lynch M. A. (2008) A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL. Neurobiol Aging.

Fennelly N. K., Sisti F., Higgins S. C., Ross P. J., van der Heide H., Mooi F. R., Boyd A. and Mills K. H. (2008) Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses. Infect Immun 76, 1257-1266.

Hickey F. B., Brereton C. F. and Mills K. H. (2008) Adenylate cycalse toxin from Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells. J Leukoc Biol.

Jarnicki A. G., Conroy H., Brereton C., Donnelly G., Toomey D., Walsh K., Sweeney C., Leavy O., Fletcher J., Lavelle E. C., Dunne P. and Mills K. H. (2008) Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics. J Immunol 180, 3797-3806.

Toomey D., Conroy H., Jarnicki A. G., Higgins S. C., Sutton C. and Mills K. H. (2008) Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma. Vaccine.

Braat H., McGuirk P., Ten Kate F. J., Huibregtse I., Dunne P. J., Hommes D. W., Van Deventer S. J. and Mills K. H. (2007) Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule. Gut 56, 351-357.

Higgins S. C., Jarnicki A. G., Lavelle E. C. and Mills K. H. (2006) TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells. J Immunol 177, 7980-7989.

Jarnicki A. G., Lysaght J., Todryk S. and Mills K. H. (2006) Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells. J Immunol 177, 896-904.

Lipinski K. S., Pelech S., Mountain A., Irvine A. S., Kraaij R., Bangma C. H., Mills K. H. and Todryk S. M. (2006) Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity. Cancer Immunol Immunother 55, 347-354.

Lysaght J., Jarnicki A. G. and Mills K. H. (2007) Reciprocal effects of Th1 and Treg cell inducing pathogen-associated immunomodulatory molecules on anti-tumor immunity. Cancer Immunol Immunother 56, 1367-1379.

Dr. Kevin Mitchell

Bargary G., Barnett K. J., Mitchell K. J. & Newell F. N. (2009) Colored-speech synaesthesia is triggered by multisensory, not unisensory, perception. Psychol Sci, 20, 529-33.

Little G. E., Lopez-Bendito G., Runker A. E., Garcia N., Pinon M. C., Chedotal A., Molnar Z. & Mitchell K. J. (2009) Specificity and plasticity of thalamocortical connections in Sema6A mutant mice. PLoS Biol, 7, e98.

Runker A. E., Little G. E., Suto F., Fujisawa H. & Mitchell K. J. (2008) Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. Neural Dev, 3, 34.

Barnett K. J., Foxe J. J., Molholm S., Kelly S. P., Shalgi S., Mitchell K. J. and Newell F. N. (2008) Differences in early sensory-perceptual processing in synesthesia: A visual evoked potential study. Neuroimage.

Bargary G. and Mitchell K. J. (2008) Synaesthesia and cortical connectivity. Trends Neurosci 31, 335-342.

Renaud J., Kerjan G., Sumita I., Zagar Y., Georget V., Kim D., Fouquet C., Suda K., Sanbo M., Suto F., Ackerman S. L., Mitchell K. J., Fujisawa H. and Chedotal A. (2008) Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells. Nat Neurosci 11, 440-449.

Raye C. L., Mitchell K. J., Reeder J. A., Greene E. J. and Johnson M. K. (2008) Refreshing one of several active representations: behavioral and functional magnetic resonance imaging differences between young and older adults. J Cogn Neurosci 20, 852-862.

Barnett K. J., Finucane C., Asher J. E., Bargary G., Corvin A. P., Newell F. N. and Mitchell K. J. (2008) Familial patterns and the origins of individual differences in synaesthesia. Cognition.

Bron R., Vermeren M., Kokot N., Little G. E., Mitchell K. J., Andrews W. and Cohen J. (2007) Boundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin - plexin mechanism. Neural Develop 2, 21.

Dolan J., Walshe K., Alsbury S., Hokamp K., O'Keeffe S., Okafuji T., Miller S. F., Tear G. and Mitchell K. J. (2007) The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genomics 8, 320.

Miller S. F., Summerhurst K., Runker A. E., Kerjan G., Friedel R. H., Chedotal A., Murphy P. and Mitchell K. J. (2007) Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Gene Expr Patterns 7, 635-644.

Mitchell K. J. (2007) The genetics of brain wiring: from molecule to mind. PLoS Biol 5, e113.

Suto F., Tsuboi M., Kamiya H., Mizuno H., Kiyama Y., Komai S., Shimizu M., Sanbo M., Yagi T., Hiromi Y., Chedotal A., Mitchell K. J., Manabe T. and Fujisawa H. (2007) Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A Control Lamina-Restricted Projection of Hippocampal Mossy Fibers. Neuron 53, 535-547.

Dr. Fiona Newell

McHugh, J. E., McDonnell, R., O'Sullivan, C., and Newell, F. N. (2009) Perceiving emotion in crowds: the role of dynamic body postures on the perception of emotion in crowded scenes, Exp Brain Res.

Bargary G., Barnett K. J., Mitchell K. J. & Newell F. N. (2009) Colored-speech synaesthesia is triggered by multisensory, not unisensory, perception. Psychol Sci, 20, 529-33.

Casey S. J., Mernagh M. & Newell F. N. (2009) Are attractive facial characteristics peculiar to the sex of a face? Q J Exp Psychol (Colchester), 62, 833-43.

Barnett K. J., Feeney J., Gormley M. & Newell F. N. (2009) An exploratory study of linguistic-colour associations across languages in multilingual synaesthetes. Q J Exp Psychol (Colchester), 62, 1343-54; quiz 1354-5.

Woods A. T., Moore A. & Newell F. N. (2008) Canonical views in haptic object perception. Perception, 37, 1867-78.

Whitaker T. A., Simoes-Franklin C. and Newell F. N. (2008) Vision and touch: Independent or integrated systems for the perception of texture? Brain Res.

Chan, J.S. & Newell, F.N., (2008).Behavioural evidence for task-dependent, 'what' versus 'where' processing within and across modalities, Perception & Psychophysics.

Barnett K. J., Finucane C., Asher J. E., Bargary G., Corvin A. P., Newell F. N. and Mitchell K. J. (2008) Familial patterns and the origins of individual differences in synaesthesia. Cognition.

Barnett K. J. and Newell F. N. (2007) Synaesthesia is associated with enhanced, self-rated visual imagery. Conscious Cogn.

Casey S. J. and Newell F. N. (2007) Are representations of unfamiliar faces independent of encoding modality? Neuropsychologia 45, 506-513.

Ernst M. O. and Newell F. N. (2007) Multisensory recognition of actively explored objects. Can J Exp Psychol 61, 242-253.

Pasqualotto A. and Newell F. N. (2007) The role of visual experience on the representation and updating of novel haptic scenes. Brain Cogn 65, 184-194.

Setti, A. & Newell FN, (2007).The effect of body and part-based motion on the recognition of unfamiliar objects, Memory & Cognition.

McDonnell R., Newell F., Carol O'Sullivan C. (2007). Smooth Movers: Perceptually Guided Human Motion Simulation, Eurographics/ ACM SIGGRAPH Symposium on Computer Animation, San Diego, U.S., August, 2007, edited by D. Metaxas and J. Popovic , ACM Press.

McDonnell R., Joerg, S., Hodgins, J., Newell, F., O'Sullivan C. (2007). Virtual Shapers & Movers: Form and Motion affect Sex Perception, APGV'07: ACM SIGGRAPH Symposium on Applied Perception in Graphics and Visualization, Tuebingen, Germany, July 2007.

Newell, F.N. & Shams, L., (2007). Special Issue of Perception: New insights into multisensory perception. Vol. 36, pp. 1415-1418

Newell, F.N., Finucane, C., Pasqualotto, A. & Vendrell, I. (2007) Active perception allows for spatial updating of object locations across modalities, Behavior Research Methods, 39, (4)

Chan J.S., Maucher T., Schemmel J., Newell F.N., Meier K.H., (2007). The Virtual Haptic Display: A device for exploring 2-D virtual shapes in the tactile modality, Behavior Research Methods, Instruments, & Computers. 39, (4), pp 802 - 810

Prof. John O’Doherty

Wunderlich, K., Rangel, A., and O'Doherty, J. P. (2009) Neural computations underlying action-based decision making in the human brain, Proc Natl Acad Sci U S A 106, 17199-17204.

Chib, V. S., Rangel, A., Shimojo, S., and O'Doherty, J. P. (2009) Evidence for a common representation of decision values for dissimilar goods in human ventromedial prefrontal cortex, J Neurosci 29, 12315-12320.

Valentin, V. V., and O'Doherty, J. P. (2009) Overlapping prediction errors in dorsal striatum during instrumental learning with juice and money reward in the human brain, J Neurophysiol 102, 3384-3391.

Tricomi E. , Balleine B. W. & O'Doherty J. P. (2009) A specific role for posterior dorsolateral striatum in human habit learning. Eur J Neurosci.

Tobler P. N., Christopoulos G. I., O'Doherty J. P., Dolan R. J. & Schultz W. (2009) Risk-dependent reward value signal in human prefrontal cortex. Proc Natl Acad Sci U S A, 106, 7185-90.

Spezio M. L., Rangel A., Alvarez R. M., O'Doherty J. P., Mattes K., Todorov A., Kim H. & Adolphs R. (2008) A neural basis for the effect of candidate appearance on election outcomes. Soc Cogn Affect Neurosci, 3, 344-52.

Tobler P. N., Christopoulos G. I., O'Doherty J. P., Dolan R. J. & Schultz W. (2008) Neuronal distortions of reward probability without choice. J Neurosci, 28, 11703-11.

Tanaka S. C., Balleine B. W. and O'Doherty J. P. (2008) Calculating consequences: brain systems that encode the causal effects of actions. J Neurosci 28, 6750-6755.

Glascher J., Hampton A. N. and O'Doherty J. P. (2008) Determining a Role for Ventromedial Prefrontal Cortex in Encoding Action-Based Value Signals During Reward-Related Decision Making. Cereb Cortex.

Bray S., Rangel A., Shimojo S., Balleine B. and O'Doherty J. P. (2008) The neural mechanisms underlying the influence of pavlovian cues on human decision making. J Neurosci 28, 5861-5866.

Hampton A. N., Bossaerts P. and O'Doherty J. P. (2008) Neural correlates of mentalizing-related computations during strategic interactions in humans. Proc Natl Acad Sci U S A 105, 6741-6746.

Schonberg T., Daw N. D., Joel D. and O'Doherty J. P. (2007) Reinforcement learning signals in the human striatum distinguish learners from nonlearners during reward-based decision making. J Neurosci 27, 12860-12867.

Kim H., Adolphs R., O'Doherty J. P. and Shimojo S. (2007) Temporal isolation of neural processes underlying face preference decisions. Proc Natl Acad Sci U S A 104, 18253-18258.

O'Doherty J. P. (2007) Lights, camembert, action! The role of human orbitofrontal cortex in encoding stimuli, rewards, and choices. Ann N Y Acad Sci 1121, 254-272.

Hampton A. N., Adolphs R., Tyszka M. J. and O'Doherty J. P. (2007) Contributions of the amygdala to reward expectancy and choice signals in human prefrontal cortex. Neuron 55, 545-555.

Murray E. A., O'Doherty J. P. and Schoenbaum G. (2007) What we know and do not know about the functions of the orbitofrontal cortex after 20 years of cross-species studies. J Neurosci 27, 8166-8169.

Bray S., Shimojo S. and O'Doherty J. P. (2007) Direct instrumental conditioning of neural activity using functional magnetic resonance imaging-derived reward feedback. J Neurosci 27, 7498-7507.

Valentin V. V., Dickinson A. and O'Doherty J. P. (2007) Determining the neural substrates of goal-directed learning in the human brain. J Neurosci 27, 4019-4026.

O'Doherty J. P., Hampton A. and Kim H. (2007) Model-based fMRI and its application to reward learning and decision making. Ann N Y Acad Sci 1104, 35-53.

Tobler P. N., O'Doherty J. P., Dolan R. J. and Schultz W. (2007) Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems. J Neurophysiol 97, 1621-1632.

Prof. Shane O’Mara

Roche, R. A., Mullally, S. L., McNulty, J. P., Hayden, J., Brennan, P., Doherty, C. P., Fitzsimons, M., McMackin, D., Prendergast, J., Sukumaran, S., Mangaoang, M. A., Robertson, I. H., and O'Mara, S. M. (2009) Prolonged rote learning produces delayed memory facilitation and metabolic changes in the hippocampus of the ageing human brain, BMC Neurosci 10, 136.

O'Mara S. M., Sanchez-Vives M. V., Brotons-Mas J. R. & O'Hare E. (2009) Roles for the subiculum in spatial information processing, memory, motivation and the temporal control of behaviour. Prog Neuropsychopharmacol Biol Psychiatry, 33(5):782-90

Cowley T. R., Fahey B. and O'Mara S. M. (2008) COX-2, but not COX-1, activity is necessary for the induction of perforant path long-term potentiation and spatial learning in vivo. Eur J Neurosci 27, 2999-3008.

Fahey B., Barlow S., Day J. S. and O'Mara S. M. (2008) Interferon-alpha-induced deficits in novel object recognition are rescued by chronic exercise. Physiol Behav 95, 125-129.

Irish M., Lawlor B. A., O'Mara S. M. and Coen R. F. (2008) Assessment of behavioural markers of autonoetic consciousness during episodic autobiographical memory retrieval: A preliminary analysis. Behav Neurol 19, 3-6.

Larkin A. E., Fahey B., Gobbo O., Callaghan C. K., Cahill E., O'Mara S. M. and Kelly A. M. (2008) Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat. Brain Res 1199, 126-132.

Fahey B., Hickey B., Kelleher D., O'Dwyer A. M. and O'Mara S. M. (2007) The widely-used anti-viral drug interferon-alpha induces depressive- and anxiogenic-like effects in healthy rats. Behav Brain Res 182, 80-87.

Reid R. E., Kim E. M., Page D., O'Mara S. M. and O'Hare E. (2007) Thyroxine replacement in an animal model of congenital hypothyroidism. Physiol Behav 91, 299-303.

Roche R. A., Commins S., Agnew F., Cassidy S., Corapi K., Leibbrand S., Lipson Z., Rickard J., Sorohan J., Wynne C. and O'Mara S. M. (2007) Concurrent task performance enhances low-level visuomotor learning. Percept Psychophys 69, 513-522.

Correia N., Mullally S., Kyaw Tun, T., Phelan, N.A., O’Mara S., Boran G., Gibney J. , (2007) Effects of 3 months Eltroxin Replacement on Neuropsychological Abnormalities in Overt and Sub-clinical Hypothyroidism, Endocrine Society 89th Annual Meeting, Toronto, Canada.

Desmond O’Neill

Martin, R., Williams, C., and O'Neill, D. (2009) Retrospective analysis of attitudes to ageing in the Economist: apocalyptic demography for opinion formers, BMJ 339, b4914.

Kearney, L., and O'Neill, D. (2009) Pay for performance and quality of care in England, N Engl J Med 361, 1709.

Hickey A., O'Hanlon A., McGee H., Donnellan C., Shelley E., Horgan F. & O'Neill D. (2009) Stroke awareness in the general population: knowledge of stroke risk factors and warning signs in older adults. BMC Geriatr, 9, 35.

Bartley M., Tobin W.O., Collins R. & O'Neill D. (2009) Stroke and newspapers: inattention or neglect? J Stroke Cerebrovasc Dis, 18, 259-61.

Whitford D. L., Hickey A., Horgan F., O'Sullivan B., McGee H. & O'Neill D. (2009) Is primary care a neglected piece of the jigsaw in ensuring optimal stroke care? Results of a national study. BMC Fam Pract, 10, 27.

Fealy G., McCarron M., O'Neill D., McCallion P., Clarke M., Small V., O'Driscoll A. & Cullen A. (2009) Effectiveness of gerontologically informed nursing assessment and referral interventions for older persons attending the emergency department: systematic review. J Adv Nurs, 65, 934-5.

Garavan R., McGee H. M., Winder R. & O'Neill D. (2009) When and how older people discuss preferences for long-term care options. J Am Geriatr Soc, 57, 750-1.

Lonergan M. T., Broderick J., Coughlan T., Collins D. R. & O'Neill D. (2009) Prescribing and enteral tubes in the general hospital. J Am Geriatr Soc, 57, 736-7.

Crawford V. L., Dinsmore J. G., Stout R. W., Donnellan C., O'Neill D. & McGee H. (2009) Stroke presentation and hospital management: comparison of neighboring healthcare systems with differing health policies. Stroke, 40, 2143-8.

Martin R. & O'Neill D. (2009) Taxing your memory. Lancet.

O'Neill D. & Collins R. (2009) Medical ethics and prisoners. Lancet, 373, 896.

Murray A. & O'Neill D. (2009) Health-care equity--for all generations? Lancet, 373, 299.

Martin A. J., Marottoli R. & O'Neill D. (2009) Driving assessment for maintaining mobility and safety in drivers with dementia. Cochrane Database Syst Rev, CD006222.

Martin R. & O'Neill D. (2009) What determines the ability to stop smoking in old age? Age Ageing, 38, 248.

Palacio A., Tamburro G., O'Neill D. & Simms C.K. (2009) Non-collision injuries in urban buses--strategies for prevention. Accid Anal Prev, 41, 1-9.

Quinlan N. & O'Neill D. (2008) "Older" or "elderly"--are medical journals sensitive to the wishes of older people? J Am Geriatr Soc, 56, 1983-4.

Sare G. M., Bath P. M., Gray L. J., Moulin T., Woimant F., England T., Geeganage C., Christensen H., De Deyn P.P., Leys D., O'Neill D. & Ringelstein E.B. (2009) The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the tinzaparin in acute ischaemic stroke trial (TAIST). Stroke, 40, 41-6.

Quinlan N. & O'Neill D. (2008) Weight loss cannot wait. Arch Intern Med, 168, 2171-2; author reply 2172.

O'Neill D., Collins R. & Coughlan T. (2008) Transient ischaemic attack: TIA or stroke with transient overt signs? BMJ, 337, a2158.

O'Dwyer C. & O'Neill D. (2008) Developing strategies for the prevention, detection and management of elder abuse: the Irish experience. J Elder Abuse Negl, 20, 169-80.

O'Brien J. G. & O'Neill D. (2008) International mosaic on the status of elder abuse and neglect from five continents. Introduction. J Elder Abuse Negl, 20, 87-90.

O'Neill D. (2008) Our demographic bounty. Lancet 372, 806.

O'Neill D., O'Dwyer C. and McGee H. (2008) Violence between intimate partners knows no age limit. Bmj 337, a1327.

Langford J., Braitman K., Charlton J., Eberhard J., O'Neill D., Staplin L. and Stutts J. (2008) TRB Workshop 2007: Licensing authorities' options for managing older driver safety--practical advice from the researchers. Traffic Inj Prev 9, 278-281.

O'Neill D., Horgan F., Hickey A. and McGee H. (2008) Long term outcome of stroke: Stroke is a chronic disease with acute events. Bmj 336, 461.

McGee H. M., O'Hanlon A., Barker M., Hickey A., Montgomery A., Conroy R. and O'Neill D. (2008) Vulnerable older people in the community: relationship between the Vulnerable Elders Survey and health service use. J Am Geriatr Soc 56, 8-15.

Caffrey N. and O'Neill D. (2007) Sexuality and health among older adults in the United States. N Engl J Med 357, 2732; author reply 2732-2733.

Gray L. J., Sprigg N., Bath P. M., Boysen G., De Deyn P. P., Leys D., O'Neill D. and Ringelstein E. B. (2007) Sex differences in quality of life in stroke survivors: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST). Stroke 38, 2960-2964.

O'Neill D. (2007) Prevention in elderly people: Later life's complexity needs a scalpel rather than an axe. Bmj 335, 361-362.

Sprigg N., Gray L. J., Bath P. M., Lindenstrom E., Boysen G., De Deyn P. P., Friis P., Leys D., Marttila R., Olsson J. E., O'Neill D., Ringelstein E. B., van der Sande J. J. and Turpie A. G. (2007) Early recovery and functional outcome are related with causal stroke subtype: data from the tinzaparin in acute ischemic stroke trial. J Stroke Cerebrovasc Dis 16, 180-184.

Breen D. A., Breen D. P., Moore J. W., Breen P. A. and O'Neill D. (2007) Driving and dementia. Bmj 334, 1365-1369.

O'Neill D. and McGee H. (2007) Oldest old are not just passive recipients of care. Bmj 334, 651.

Falconer M. and O'Neill D. (2007) Age-proofing hospital surge capacity. Lancet 369, 822-823; author reply 823.

Robinson D. J. and O'Neill D. (2007) Access to health care records after death: balancing confidentiality with appropriate disclosure. Jama 297, 634-636.

Falconer M. and O'Neill D. (2007) Profiling disability within nursing homes: a census-based approach. Age Ageing 36, 209-213.

O'Neill D. (2007) Driving and dementia. Cmaj 176, 351.

Sprigg N., Gray L. J., Bath P. M., Lindenstrom E., Boysen G., De Deyn P. P., Friis P., Leys D., Marttila R., Olsson J. E., O'Neill D., Ringelstein E. B., van der Sande J. J. and Turpie A. G. (2007) Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial' (TAIST). J Neurol Sci 254, 54-59.

Prof. Richard Reilly

Kimmich O., Bradley D., Whelan R., Mulrooney N., Reilly R.B., Hutchinson S., O’Riordan S., Hutchinson M., “Sporadic adult onset primary torsion dystonia is a genetic disorder by the temporal discrimination test”, Brain, March 2011. Manuscript ID BRAIN-2011-00377.R1

Bradley, D., Whelan R., Kimmich O., O’Riordan S., Mulrooney N., Brady P., Walsh, R., Reilly, R.B., Hutchinson, S., Molloy, F., & Hutchinson, M. Temporal discrimination thresholds in adult-onset primary torsion dystonia: an analysis by task type and by dystonia phenotype. Journal of Neurology, in press DOI 10.1007/ s00415-011-6125-7

Tsanov M., Chah E, Vann S.D., Reilly R.B, Erichsen J.T., Aggleton J.P., O’Mara S.M., Crossover between Theta Rhythm and Head Directional Processing in Anterior Thalamus, Journal of Neuroscience. JN-RM-0353-11R3

Setti A, Finnigan S., Sobolewski R., McLaren L., Robertson I.H., Reilly R.B., Kenny R.A., Newell F.N., “Audiovisual temporal discrimination is less efficient with ageing: An ERP study”, NeuroReport, in press.

McHugh J, Reilly R.B., Connolly S, “Examining the effects of age, sex, and BMI on normative median motor nerve excitability measurements”, Clinical Neurophysiology, Apr 2011

Kiiski, H., Reilly, R.B., Lonergan, R., Kelly, S., O'Brien, M., Kinsella, K., Bramham, J., Burke, E.T., O’Donnchadha, S., Nolan, H., Hutchinson, M., Tubridy, N, & Whelan, R. Change in PASAT performance correlates with change in P3 ERP amplitude over a 12-month period in multiple sclerosis patients. Journal of the Neurological Sciences, 305, 45-52, 2011

Kiiski, H., Whelan, R., Lonergan, R., Nolan, H., Kinsella, K., Hutchinson, M., Tubridy, N., Reilly, R.B. Preliminary Evidence for Correlation Between PASAT Performance and P3a and P3b amplitudes in progressive multiple sclerosis. European Journal of Neurology, 18, 792-795, 2011

Chah E, Hok V, Della-Chiesa A., Miller J.J.H, O’Mara S.M, Reilly R.B., “Automated spike sorting algorithm based on laplacian eigenmaps and k-means clustering” Journal of Neural Engineering, 8 016006 doi: 10.1088/1741-2560/8/1/016006

Tsanov M., Chah E, Vann S.D., Reilly R.B, Erichsen J.T., Aggleton J.P., O’Mara S.M., “Oscillatory Entrainment of Thalamic Neurons By Theta Rhythm In Freely-Moving Rats”, Journal of Neurophysiology, 2011 105:4-17

Moran RJ, Campo P, Maestú F, Reilly RB, Dolan RJ and Strange BA. “Peak frequency in the theta and alpha bands correlates with human working memory capacity”, Front. Hum. Neurosci. 4:200. doi: 10.3389/fnhum.2010.00200, 2010.

Power A., Lalor E, Reilly R.B., “Endogexnous Auditory Spatial Attention Modulates Obligatory Sensory Activity in Auditory Cortex” Cerebral Cortex, Vol. 21(6), pp1223-30, 2011.

Nolan H, Whelan R, Reilly R.B “FASTER: Fully Automated Statistical Thresholding for EEG artifact Rejection”, Journal of Neuroscience Methods, Volume 192, Issue 1, 30 September 2010, Pages 152-162

Rapcan V., D’Arcy S., Yeap S., N, Thakore J., Reilly R.B, “Acoustic and Temporal Analysis of Speech: A Potential Biomarker for Schizophrenia” Medical Engineering & Physics, 2010 Nov;32(9):1074-9.

Cervigon R., Reilly R.B., Castells F., Moreno J., Millet J., “Entropy Measurements in Paroxysmal and Persistent Atrial Fibrillation”, Physiological Measurement, 31 1011. doi: 10.1088/0967-3334/31/7/010

Whelan R, Lonergan R, Kiiski H, Nolan H, Kinsella K, Hutchinson M, Tubridy N, Reilly RB. “Impaired information processing speed and attention allocation in multiple sclerosis patients versus controls: A high-density EEG study”. J Neurol Sci. Volume 293, Issues 1-2, 15 June 2010, Pages 45-50

Whelan R, Lonergan R, Kiiski H, Nolan H, Kinsella K, Bramham J, O'Brien MC, Reilly RB, Hutchinson M, Tubridy N. “A high-density ERP study reveals latency, amplitude, and topographical differences in multiple sclerosis patients versus controls”. Clin Neurophysiol. 2010. doi:10.1016/j.clinph.2010.03.019

Bradley, D., Whelan, R., Walsh, R., O'Dwyer, J., Reilly, R.B., Hutchinson, S., Molloy, F., Hutchinson M., “Comparing endophenotypes in Adult-onset Primary Torsion Dystonia”, Movement Disorders, Vol. 25, No. 1, pp. 84–90, 2010.

Yeap, S., Kelly, S. P., Reilly, R. B., Thakore, J. H., and Foxe, J. J. (2009) Visual sensory processing deficits in patients with bipolar disorder revealed through high-density electrical mapping, J Psychiatry Neurosci 34, 459-464.

Lalor E. C., Power A. J., Reilly R. B. & Foxe J. J. (2009) Resolving Precise Temporal Processing Properties of the Auditory System Using Continuous Stimuli. J Neurophysiol. 102(1):349-59.

Cervigon R., Moreno J., Sanchez C., Reilly R. B., Villacastin J., Millet J. & Castells F. (2009) Atrial fibrillation organization: quantification of propofol effects. Med Biol Eng Comput, 47, 333-41.

Wormald R. N., Moran R. J., Reilly R. B. & Lacy P. D. (2008) Performance of an automated, remote system to detect vocal fold paralysis. Ann Otol Rhinol Laryngol, 117, 834-8.

Lalor E. C., Yeap S., Reilly R. B., Pearlmutter B. A. and Foxe J. J. (2008) Dissecting the cellular contributions to early visual sensory processing deficits in schizophrenia using the VESPA evoked response. Schizophr Res 98, 256-264.

Greene B. R., Boylan G. B., Reilly R. B., de Chazal P. and Connolly S. (2007) Combination of EEG and ECG for improved automatic neonatal seizure detection. Clin Neurophysiol 118, 1348-1359.

Greene B. R., de Chazal P., Boylan G. B., Connolly S. and Reilly R. B. (2007) Electrocardiogram based neonatal seizure detection. IEEE Trans Biomed Eng 54, 673-682.

Minogue C. M., Caulfield B. M. and Reilly R. B. (2007) What are the electrical stimulation design parameters for maximum VO2 aimed at cardio-pulmonary rehabilitation? Conf Proc IEEE Eng Med Biol Soc 2007, 2428-2431.

Sobolewski R., O'Mullane B., Knapp R. B. and Reilly R. B. (2007) A portable neurological monitor for use in cognitive function studies. Conf Proc IEEE Eng Med Biol Soc 2007, 2940-2943.

Power A. J., Lalor E. C. and Reilly R. B. (2007) Eliciting audio evoked potentials using continuous stimuli. Conf Proc IEEE Eng Med Biol Soc 2007, 4264-4267.

Lalor E. C., Kelly S. P., Pearlmutter B. A., Reilly R. B. and Foxe J. J. (2007) Isolating endogenous visuo-spatial attentional effects using the novel visual-evoked spread spectrum analysis (VESPA) technique. Eur J Neurosci 26, 3536-3542.

Prof. Mani Ramaswami

Cziko A. M., McCann C. T., Howlett I. C., Barbee S. A., Duncan R. P., Luedemann R., Zarnescu D., Zinsmaier K. E., Parker R. R. & Ramaswami M. (2009) Genetic Modifiers of DFMR1 Encode RNA-Granule Components in Drosophila. Genetics. 182(4):1051-60

Chiang A., Priya R., Ramaswami M., Vijayraghavan K. & Rodrigues V. (2009) Neuronal activity and Wnt signaling act through Gsk3-beta to regulate axonal integrity in mature Drosophila olfactory sensory neurons. Development, 136, 1273-82.

Kumar V., Fricke R., Bhar D., Reddy-Alla S., Krishnan K. S., Bogdan S. & Ramaswami M. (2009) Syndapin promotes formation of a postsynaptic membrane system in Drosophila. Mol Biol Cell, 20, 2254-64.

Kim S. M., Kumar V., Lin Y. Q., Karunanithi S. & Ramaswami M. (2009) Fos and Jun potentiate individual release sites and mobilize the reserve synaptic vesicle pool at the Drosophila larval motor synapse. Proc Natl Acad Sci U S A, 106, 4000-5.

Pollock JD & Ramaswami M (2009) The Genetics and Epigenetics of Addiction. J Neurogenet, 23(3):251

Kumar V., Alla S. R., Krishnan K. S. & Ramaswami M. (2009) Syndapin is dispensable for synaptic vesicle endocytosis at the Drosophila larval neuromuscular junction. Mol Cell Neurosci, 40, 234-41.

Kwak J. E., Drier E., Barbee S. A., Ramaswami M., Yin J. C. and Wickens M. (2008) GLD2 poly(A) polymerase is required for long-term memory. Proc Natl Acad Sci U S A. 105(38):14644-9

Hartwig C. L., Worrell J., Levine R. B., Ramaswami M. and Sanyal S. (2008) Normal dendrite growth in Drosophila motor neurons requires the AP-1 transcription factor. Dev Neurobiol 68, 1225-1242.

Beckham C., Hilliker A., Cziko A. M., Noueiry A., Ramaswami M. and Parker R. (2008) The DEAD-Box RNA Helicase Ded1p Affects and Accumulates in Saccharomyces cerevisiae P-Bodies. Mol Biol Cell 19, 984-993.

Wu C. F. and Ramaswami M. (2007) The origins of neurogenetics. J Neurogenet 21, 165-167.

Santos M. C., Hart P. S., Ramaswami M., Kanno C. M., Hart T. C. and Line S. R. (2007) Exclusion of known gene for enamel development in two Brazilian families with amelogenesis imperfecta. Head Face Med 3, 8.

Jang S. I., Lee E. J., Hart P. S., Ramaswami M., Pallos D. and Hart T. C. (2007) Germ line gain of function with SOS1 mutation in hereditary gingival fibromatosis. J Biol Chem 282, 20245-20255.

Hillebrand J., Barbee S. A. and Ramaswami M. (2007) P-body components, microRNA regulation, and synaptic plasticity. ScientificWorldJournal 7, 178-190.

Prof. Ian Robertson

Roche RA, Mullally SL, McNulty JP, Hayden J, Brennan P, Doherty CP, Fitzsimons M, McMackin D, Prendergast J, Sukumaran S, Mangaoang MA, Robertson IH & O'Mara SM (2009) Prolonged rote learning produces delayed memory facilitation and metabolic changes in the hippocampus of the ageing human brain. BMC Neurosci, 10, 136.

Hogan M. J., Kelly C. A., Verrier D., Newell J., Hasher L. & Robertson I. H. (2009) Optimal time-of-day and consolidation of learning in younger and older adults. Exp Aging Res, 35, 107-28.

Robertson I. H. (2008) Traumatic brain injury: recovery, prediction, and the clinician. Arch Phys Med Rehabil, 89, S1-2.

Greene C. M., Bellgrove M. A., Gill M. & Robertson I. H. (2009) Noradrenergic genotype predicts lapses in sustained attention. Neuropsychologia, 47, 591-4.

O'Connell R. G., Dockree P. M., Bellgrove M. A., Turin A., Ward S., Foxe J. J. & Robertson I. H. (2009) Two types of action error: electrophysiological evidence for separable inhibitory and sustained attention neural mechanisms producing error on go/no-go tasks. J Cogn Neurosci, 21, 93-104.

Magno E., Simoes-Franklin C., Robertson I. H. & Garavan H. (2008) The Role of the Dorsal Anterior Cingulate in Evaluating Behavior for Achieving Gains and Avoiding Losses. J Cogn Neurosci, 21, 2328-42.

Schweizer T. A., Levine B., Rewilak D., O'Connor C., Turner G., Alexander M. P., Cusimano M., Manly T., Robertson I. H. and Stuss D. T. (2008) Rehabilitation of executive functioning after focal damage to the cerebellum. Neurorehabil Neural Repair 22, 72-77.

O'Connell R. G., Bellgrove M. A., Dockree P. M., Lau A., Fitzgerald M. and Robertson I. H. (2008) Self-Alert Training: Volitional modulation of autonomic arousal improves sustained attention. Neuropsychologia 46, 1379-1390.

Johnson K. A., Kelly S. P., Robertson I. H., Barry E., Mulligan A., Daly M., Lambert D., McDonnell C., Connor T. J., Hawi Z., Gill M. and Bellgrove M. A. (2008) Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls. Am J Med Genet B Neuropsychiatr Genet. 147B(6), 927-937

Johnson K. A., Barry E., Bellgrove M. A., Cox M., Kelly S. P., Daibhis A., Daly M., Keavey M., Watchorn A., Fitzgerald M., McNicholas F., Kirley A., Robertson I. H. and Gill M. (2008) Dissociation in response to methylphenidate on response variability in a group of medication naive children with ADHD. Neuropsychologia 46, 1532-1541.

Hoerold D., Dockree P. M., O'Keeffe F. M., Bates H., Pertl M. and Robertson I. H. (2008) Neuropsychology of self-awareness in young adults. Exp Brain Res 186, 509-515.

Bellgrove M. A., Barry E., Johnson K. A., Cox M., Daibhis A., Daly M., Hawi Z., Lambert D., Fitzgerald M., McNicholas F., Robertson I. H., Gill M. and Kirley A. (2007) Spatial Attentional Bias as a Marker of Genetic Risk, Symptom Severity, and Stimulant Response in ADHD. Neuropsychopharmacology 33(10), 2536-2545.

Chambers C. D., Bellgrove M. A., Stokes M. G., Henderson T. R., Garavan H., Robertson I. H., Morris A. P. and Mattingley J. B. (2006) Executive "brake failure" following deactivation of human frontal lobe. J Cogn Neurosci 18, 444-455.

Johnson K. A., Kelly S. P., Bellgrove M. A., Barry E., Cox M., Gill M. and Robertson I. H. (2007a) Response variability in attention deficit hyperactivity disorder: evidence for neuropsychological heterogeneity. Neuropsychologia 45, 630-638.

Levine B., Stuss D. T., Winocur G., Binns M. A., Fahy L., Mandic M., Bridges K. and Robertson I. H. (2007) Cognitive rehabilitation in the elderly: effects on strategic behavior in relation to goal management. J Int Neuropsychol Soc 13, 143-152.

McAvinue L. P. and Robertson I. H. (2007) Relationship between visual and motor imagery. Percept Mot Skills 104, 823-843.

O'Keeffe F., Dockree P., Moloney P., Carton S. and Robertson I. H. (2007) Awareness of deficits in traumatic brain injury: a multidimensional approach to assessing metacognitive knowledge and online-awareness. J Int Neuropsychol Soc 13, 38-49.

O'Keeffe F M., Dockree P. M., Moloney P., Carton S. and Robertson I. H. (2007) Characterising error-awareness of attentional lapses and inhibitory control failures in patients with traumatic brain injury. Exp Brain Res 180, 59-67.

O'Keeffe F. M., Murray B., Coen R. F., Dockree P. M., Bellgrove M. A., Garavan H., Lynch T. and Robertson I. H. (2007) Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy. Brain 130, 753-764.

Stuss D. T., Robertson I. H., Craik F. I., Levine B., Alexander M. P., Black S., Dawson D., Binns M. A., Palmer H., Downey-Lamb M. and Winocur G. (2007) Cognitive rehabilitation in the elderly: a randomized trial to evaluate a new protocol. J Int Neuropsychol Soc 13, 120-131.

Winocur G., Craik F. I., Levine B., Robertson I. H., Binns M. A., Alexander M., Black S., Dawson D., Palmer H., McHugh T. and Stuss D. T. (2007) Cognitive rehabilitation in the elderly: overview and future directions. J Int Neuropsychol Soc 13, 166-171.

Prof. Michael Rowan

Hu, N. W., Klyubin, I., Anwy, R., and Rowan, M. J. (2009) GluN2B subunit-containing NMDA receptor antagonists prevent Abeta-mediated synaptic plasticity disruption in vivo, Proc Natl Acad Sci U S A 106, 20504-20509.

Ondrejcak T., Klyubin I., Hu N.W., Barry A.E., Cullen W.K. & Rowan M.J. (2009) Alzheimer's Disease Amyloid beta-Protein and Synaptic Function. Neuromolecular Med. 12(1):13-26

Ryan B.K., Vollmayr B., Klyubin I., Gass P. & Rowan M.J. (2009) Persistent inhibition of hippocampal long-term potentiation in vivo by learned helplessness stress. Hippocampus.

Welsby P. J., Rowan M. J. & Anwyl R. (2009) Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus. Eur J Neurosci, 29, 65-75.

Ryan B., Musazzi L., Mallei A., Tardito D., Gruber S. H., El Khoury A., Anwyl R., Racagni G. Mathe A. A., Rowan M. J. & Popoli M. (2009) Remodelling by early-life stress of NMDA receptor-dependent synaptic plasticity in a gene-environment rat model of depression. Int J Neuropsychopharmacol, 12, 553-9.

Hu N. W., Smith I. M., Walsh D. M. and Rowan M. J. (2008) Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo. Brain 131, 2414-2424.

Shankar G. M., Li S., Mehta T. H., Garcia-Munoz A., Shepardson N. E., Smith I., Brett F. M., Farrell M. A., Rowan M. J., Lemere C. A., Regan C. M., Walsh D. M., Sabatini B. L. and Selkoe D. J. (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14, 837-842.

Ryan B. K., Anwyl R. and Rowan M. J. (2008) 5-HT2 receptor-mediated reversal of the inhibition of hippocampal long-term potentiation by acute inescapable stress. Neuropharmacology 55, 175-182.

Wu J., Harney S., Rowan M. J. and Anwyl R. (2008) Involvement of group I mGluRs in LTP induced by strong high frequency stimulation in the dentate gyrus in vitro. Neurosci Lett 436, 235-238.

Wang Q. W., Rowan M. J. and Anwyl R. (2008) Inhibition of LTP by beta-amyloid is prevented by activation of beta2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway. Neurobiol Aging.

Welsby P. J., Rowan M. J. and Anwyl R. (2007) Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP. Neuropharmacology 53, 188-195.

Wang Q., Klyubin I., Wright S., Griswold-Prenner I., Rowan M. J. and Anwyl R. (2007) Alphav integrins mediate beta-amyloid induced inhibition of long-term potentiation. Neurobiol Aging.

Rowan M. J., Klyubin I., Wang Q., Hu N. W. and Anwyl R. (2007) Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction. Biochem Soc Trans 35, 1219-1223.

Li S., Cullen W. K., Anwyl R. and Rowan M. J. (2007) Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 144, 754-761.

Dr. Daniel Ulrich

Czarnecki A., Birtoli B. and Ulrich D. (2007) Cellular mechanisms of burst firing-mediated long-term depression in rat neocortical pyramidal cells. J Physiol 578, 471-479.

Ulrich D. and Bettler B. (2007) GABA(B) receptors: synaptic functions and mechanisms of diversity. Curr Opin Neurobiol 17, 298-303.
Ulrich D., Besseyrias V. and Bettler B. (2007) Functional mapping of GABA(B)-receptor subtypes in the thalamus. J Neurophysiol 98, 3791-3795.

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TCIN PI Publications 2007-2009

Prof. Roger Anwyl

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