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Dr Gary Donohoe

  • Position: Adjunct Professor in Clinical Psychology
  • Contact details: NUIG, Galway
  • Email: GARY.DONOHOE@nuigalway.ie
  • Telephone:


Research Interests

My interest is in the genetic, cognitive, and clinical aspects of schizophrenia and the related psychosis.Within the Neuropsychiatric Genetics Research Group at TCD, my work focuses on understanding cognitive measures and how they inter-relate, and using these to elucidate the role of candidate risk genes for schizophrenia. By combining clinical, behavioural, neurophysiological, and neuroimaging techniques, we can explore in vivo the impact of these variants on brain structure and function.

Recent Publications

Donohoe, G., Rose, E., Frodl, T., Morris, D., Spoletini, I., Adriano, F., Bernardini, S., Caltagirone, C., Bossu, P., Gill, M., Corvin, A. P., and Spalletta, G. (2011) ZNF804A risk allele is associated with relatively intact gray matter volume in patients with schizophrenia, NeuroImage 54, 2132-2137.

Donohoe, G., Walters, J., Morris, D. W., Da Costa, A., Rose, E., Hargreaves, A., Maher, K., Hayes, E., Giegling, I., Hartmann, A. M., Moller, H. J., Muglia, P., Moskvina, V., Owen, M. J., O'Donovan, M. C., Gill, M., Corvin, A., and Rujescu, D. (2011) A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809, Schizophrenia research 125, 304-306.

Riley, B. P., Ruggeri, M., Schall, U., Schulze, T. G., Schwab, S. G., Scott, R. J., Shi, J., Sigurdsson, E., Silverman, J. M., Spencer, C. C., Stefansson, K., Strange, A., Strengman, E., Stroup, T. S., Suvisaari, J., Terenius, L., Thirumalai, S., Thygesen, J. H., Timm, S., Toncheva, D., van den Oord, E., van Os, J., van Winkel, R., Veldink, J., Walsh, D., Wang, A. G., Wiersma, D., Wildenauer, D. B., Williams, H. J., Williams, N. M., Wormley, B., Zammit, S., Sullivan, P. F., O'Donovan, M. C., Daly, M. J., Gejman, P. V., and Schizophrenia Psychiatric Genome-Wide Association Study, C. (2011) Genome-wide association study identifies five new schizophrenia loci, Nature genetics 43, 969-976.

Donohoe, G., Walters, J., Morris, D. W., Da Costa, A., Rose, E., Hargreaves, A., Maher, K., Hayes, E., Giegling, I., Hartmann, A. M., Moller, H. J., Muglia, P., Moskvina, V., Owen, M. J., O'Donovan, M. C., Gill, M., Corvin, A., and Rujescu, D. A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809, Schizophr Res. 2011 Feb;125(2-3):304-6.

Donohoe, G., Morris, D. W., and Corvin, A. (2010) The psychosis susceptibility gene ZNF804A: associations, functions, and phenotypes, Schizophrenia bulletin 36, 904-909.

Walters, J. T., Corvin, A., Owen, M. J., Williams, H., Dragovic, M., Quinn, E. M., Judge, R., Smith, D. J., Norton, N., Giegling, I., Hartmann, A. M., Moller, H. J., Muglia, P., Moskvina, V., Dwyer, S., O'Donoghue, T., Morar, B., Cooper, M., Chandler, D., Jablensky, A., Gill, M., Kaladjieva, L., Morris, D. W., O'Donovan, M. C., Rujescu, D., and Donohoe, G. (2010) Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia, Archives of general psychiatry 67, 692-700.

Donohoe, G., Frodl, T., Morris, D., Spoletini, I., Cannon, D. M., Cherubini, A., Caltagirone, C., Bossu, P., McDonald, C., Gill, M., Corvin, A. P., and Spalletta, G. (2010) Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 35, 368-373.

Frodl, T., Reinhold, E., Koutsouleris, N., Donohoe, G., Bondy, B., Reiser, M., Moller, H. J., and Meisenzahl, E. M. (2010) Childhood stress, serotonin transporter gene and brain structures in major depression, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 35, 1383-1390.

Gilks, W. P., Allott, E. H., Donohoe, G., Cummings, E., Gill, M., Corvin, A. P., and Morris, D. W. (2010) Replicated genetic evidence supports a role for HOMER2 in schizophrenia, Neuroscience letters 468, 229-233.

Gilks, W. P., Allott, E. H., Donohoe, G., Cummings, E., International Schizophrenia, C., Gill, M., Corvin, A. P., and Morris, D. W. (2010) Replicated genetic evidence supports a role for HOMER2 in schizophrenia, Neuroscience letters 468, 229-233.

Donohoe, G., Hayden, J., McGlade, N., O'Grada, C., Burke, T., Barry, S., Behan, C., Dinan, T. G., O'Callaghan, E., Gill, M., and Corvin, A. P. (2009) Is "clinical" insight the same as "cognitive" insight in schizophrenia?, Journal of the International Neuropsychological Society : JINS 15, 471-475.

Donohoe, G., Walters, J., Morris, D. W., Quinn, E. M., Judge, R., Norton, N., Giegling, I., Hartmann, A. M., Moller, H. J., Muglia, P., Williams, H., Moskvina, V., Peel, R., O'Donoghue, T., Owen, M. J., O'Donovan, M. C., Gill, M., Rujescu, D., and Corvin, A. (2009) Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects, Archives of general psychiatry 66, 1045-1054.

O'Grada, C., Barry, S., McGlade, N., Behan, C., Haq, F., Hayden, J., O'Donoghue, T., Peel, R., Morris, D. W., O'Callaghan, E., Gill, M., Corvin, A. P., Dinan, T. G., and Donohoe, G. (2009) Does the ability to sustain attention underlie symptom severity in schizophrenia?, Schizophrenia research 107, 319-323.

TCIN publications

Research Funding

National Alliance for Research on Schizophrenia and Depression, Science Foundation Ireland, Higher Education Authority, Wellcome Trust.


Email: neuroscience@tcd.ie
Last updated 30 September 2015

Associations

In association with:
Ireland's EU Structural Funds Programmes 2007-2013, NDP, European Union Structural Funds and HEA