Course GE3095 Genetics Logo
Homepage
Cytogenetics
Pedigrees
DNA
Protein

Protein Tools

Sequence Alignment

2Structure

Prion Protein

3D Structure

Metabolic

Protein Sequence Lab

At the end of these exercises you should be able -:
  1. To appreciate the usefulness of sequence  alignment programs (the theory behind these is not our object here so we should be cautions with our conclusions). For this you will use the facilities available at SWISSPROT.
  2. To find and view 3D structures of proteins using public databases and resources.
  3. To relate protein structure to protein function. Our study is centered of rhodopsin but you could use, under supervision, any protein of your choice. Rhodopsin is the photoreceptor in the vertebrate retinal rods, and there is a similar protein found in photosensitive bacteria.
  4. To speculate on how mutations can alter protein function, and to put this information in the context of human pathology and evolution.
  5. To appreciate the contribution of human pathology and genetics databases in the study of protein function.

    Explore the tools available from the 'Tools' button on the left (green band). The other buttons will take you to different exercises.