TCBE postgraduate student, Tariq Mesallati, awarded the 2014 Engineers Ireland Biomedical Research Medal
6th February 2014
Mr Tariq Mesallati (left) receiving his medal which was sponsored by Depuy
Trinity Centre for BioEngineering postgraduate student, Tariq Mesallati, was recently awarded the 2014 Engineers Ireland Biomedical Research Medal for his significant contribution to the field of biomedical engineering research. Tariq was selected as the winner from a shortlist of finalists after presenting his research paper at the 20th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland. TCBE researchers received numerous awards at this years 20th Annual Conference of the Bioengineering Section of the Royal Academy of Medicine in Ireland (RAMI), which was held on the 24th and 25th of January in Limerick.
Tariq’s research paper, entitled ”Tissue engineering scaled-up, anatomically accurate osteochondral constructs for joint resurfacing”, focuses on treating osteoarthritis. The global objective of this study was to tissue engineer a scaled-up, anatomically shaped, osteochondral construct suitable for partial or total joint resurfacing, with the long term aim of providing a tissue engineered treatment option for the millions of people suffering from osteoarthritis worldwide. The osseous layer of osteochondral constructs was generated by promoting endochondral ossification within an MSC seeded alginate hydrogel. Co-culture of CCs and MSCs was found to lead to the development of thick, phenotypically stable cartilage in the chondral layer. Importantly for cartilage tissue engineering, this is the first study demonstrating that co-culture can suppress hypertrophy and endochondral bone formation in vivo. The final phase of the study demonstrated that it is possible to scale-up tissue engineering approaches to generate anatomically shaped, biological implants of a clinically relevant size.
At the conference Tariq was presented with a commemorative Engineers Ireland medal and a cheque for €1000 sponsored by Depuy.