Publications

NATURAL KILLER CELLS GROUP

Dr Clair M Gardiner

Dunphy S, Gardiner CM (2011). NK cells and psoriasis. J Biomed Biotechnol. 2011;2011:248317. Epub 2011 May 26.

Fadda L, O'Connor GM, Kumar S, Piechocka-Trocha A, Gardiner CM, Carrington M, McVicar DW, Altfeld M (2011). Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules. J Virol. 85(12):5970-4. Epub 2011 Apr 6.

Dring M, Morrison M, McSharry B, Guinan K, Hagan R, Irish HCV Research Consortium, O'Farrelly C and Gardiner CM (2011). Innate immune genes synergise to predict increased risk of chronic HCV infection. Proceedings of the National Academy of Sciences 108(14):5736-41.

Guinan KJ, Cunningham RT, Meenagh A, Gonzales A, Dring MM, McGuinness BW, Middleton D and Gardiner CM (2010). Signatures of natural selection and co-evolution between Killer cell immunoglobulin-like receptors (KIR) and HLA class I genes. Genes and Immunity 11(6):467-78.

McSharry B and Gardiner CM (2009). The Role of NK cells in Bacterial Infections. In "Natural Killer Cells - at the forefront of modern Immunology" Ed. Zimmer J, Publisher Springer.

Guinan KJ, Cunningham RT, Meenagh A, Dring MM, Middleton D and Gardiner CM (2009). Receptor systems controlling Natural Killer cell function are genetically stratified in Europe. Genes and Immunity 11(1):67-78. Epub 2009 Aug 20.

Athié-Morales V, O'Connor GM and Gardiner CM (2008). Activation of Human Natural Killer Cells by the Bacterial Pathogen Associated Molecular Pattern Muramyl Dipeptide. Journal of Immunology 180:4082-9.

Gardiner CM Killer cell immunoglobulin-like receptors on NK cells: the how, where and why? (2008) International Journal of Immunogenetics 35:1-8.

O'Connor GM, Holmes A, Mulcahy F, Gardiner CM. Natural Killer cells from long-term non-progressor HIV patients are characterized by altered phenotype and function. Clin Immunol. 2007 Sep;124(3):277-83

O'Connor GM, Guinan K, Cunningham RT, Middleton D, Parham P and Gardiner CM (2007). Functional Polymorphism of the KIR3DL1/S1 Receptor on Human NK Cells. J. Immunol 178: 235-41

O’Connor GM, Hart OM and Gardiner CM (2006). Putting the NK cell in its Place. Immunology 117:1-10.

Hart OM, Athie-Morales V, O’Connor, GM and Gardiner CM (2005). TLR7/8 mediated activation of human NK cells results in accessory cell dependent IFN- g production. J Immunol. 175: 1636-42.

Pando MJ, Gardiner CM, Gleimer M, McQueen KL, Parham P (2003). The protein made from a common allele of KIR3DL1 (3DL1*004) is poorly expressed at cell surfaces due to substitution at positions 86 in Ig domain 0 and 182 in Ig domain 1. J Immunol. 171:6640-9.

Gomez-Lozano N, Gardiner CM, Parham P, Vilches C (2002). Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B. Immunogenetics. 54:314-9.

HG Shilling, LA Guethlein, NW Cheng, CM Gardiner, D Tyan and P Parham (2002). Genetic Control of Human NK Cell Repertoires J Immunol . 169:239-47.

HG Shilling, LA Guethlein, NW Cheng, CM Gardiner, R Rodriguez, D Tyan and P Parham (2002). KIR Allelic Polymorphism is a Major Component of KIR Haplotype Diversity J Immunol.168:2307-15.

CM Gardiner, LA Guethlein, HG Shilling, M Pando, WH Carr, R Rajalingam, C Vilches and P Parham (2001). Different NK Cell Surface Phenotypes Defined by the DX9 Antibody are Due to KIR3DL1 Gene Polymorphism J. Immunol.166:2992-3001.

R. Rajalingam, CM Gardiner, F Canavez, C Vilchez and P Parham (2001). Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors. Tissue Antigens 57:22-31.

C Vilches, CM Gardiner and P Parham (2000). Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene. J Immunol 165:6416-21.

C Vilches, M Pando,R Rajalingam, CM Gardiner and P Parham (2000). Discovery of two novel variants of KIR2DS5 reveals this gene to be a common component of the human KIR ‘B’ haplotypes. Tissue Antignes 56:453-6.

C Vilches, R Rajalingam, M Uhrberg, CM Gardiner, N Young and P Parham (2000). KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of immunogobulin-like domains J Immunol 164:5797-804.

CM Gardiner (1999). Quick Guide: Natural Killer Cells. Current Biology 9:716.

CM Gardiner, A O’Meara and DJ Reen (1998). Differential Cytotoxicity of Cord Blood and Bone marrow Derived NK Cells. Blood 91:207-213.

CM Gardiner and DJ Reen (1998). Differential Cytokine Regulation of NK Cell-Mediated Cytotoxicity. Immunology 93:511-517.

CM Gardiner, DJ Reen and A O’Meara (1995). Recognition of Unusual Presentation of Natural Killer Cell Leukemia. Am J Hematol 50: 133-139.

Further information on the Natural Killer Cells Research Group

[Top of Page]

Trinity College Dublin

Publications

NATURAL KILLER CELLS GROUP

Dr Clair M Gardiner